Product Information
Name:Zosuquidar Trihydrochloride
Controlled Product
Synonyms:
- (αR)-4-[(1aα,6α,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-1-piperazineethanol Hydrochloride
- Zosuquidar Hydrochloride
- LY 335979
- RS 33295-198
Brand:TRC
Description:Applications Multi-drug resistance (MDR) modulator; selective inhibitor of P-glycoprotein (P-gp). Antineoplastic adjunct (chemosensitizer).References Green, L.J., et al.: Biochem. Pharmacol., 61, 1393 (2001), Shepard, R.L., et al.: Int. J. Cancer, 103, 121 (2003),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:636.99
Formula:C32H31F2N3O2·3ClH
Color/Form:Neat
InChI:InChI=1S/C32H31F2N3O2.3ClH/c33-32(34)29-22-7-1-3-9-24(22)31(25-10-4-2-8-23(25)30(29)32)37-17-15-36(16-18-37)19-21(38)20-39-28-13-5-12-27-26(28)11-6-14-35-27;;;/h1-14,21,29-31,38H,15-20H2;3*1H/t21-,29-,30+,31-;;;/m1.../s1
InChI key:InChIKey=VQJFFWJUYDGTQZ-FCNWNIDBSA-N
SMILES:Cl.O[C@@H](COc1cccc2ncccc12)CN1CCN([C@@H]2c3ccccc3[C@@H]3[C@H](c4ccccc42)C3(F)F)CC1
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