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Lenalidomide-5-bromopentanamide
CAS:<p>Lenalidomide-5-bromopentanamide is a component of PROTACATR degrader-2, serving as an E3 ligase ligand-linker conjugate. It is composed of the CRBN ligand Lenalidomide and the linker 5-Bromopentanoyl chloride. This compound is utilized in the synthesis of PROTACs.</p>Formula:C18H20BrN3O4Molecular weight:422.27Navitoclax
CAS:<p>View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.</p>Formula:C47H55ClF3N5O6S3Purity:95.82% - >99.99%Color and Shape:Pale Yellow SolidMolecular weight:974.61Diacetolol
CAS:<p>Diacetolol is the major metabolite of acebutolol, a selective beta blockers used to treat hypertension, angina pectoris and arrhythmia.</p>Formula:C16H24N2O4Color and Shape:SolidMolecular weight:308.37E3 Ligase Ligand-linker Conjugate 110
<p>E3LigaseLigand-linker Conjugate 110 is an E3 ligase and linker conjugate designed for the synthesis of BcI-2/BcI-xPROTAC degraders.</p>Formula:C30H40N4O8SMolecular weight:616.25669Thalidomide-N-C3-O-C4-O-C3-OH
<p>Thalidomide-N-C3-O-C4-O-C3-OH is a conjugate of an E3 ligase ligand and a linker, used in the synthesis of the Aster-APROTAC degrader.</p>Formula:C23H31N3O7Molecular weight:461.2162(S,R,S)-AHPC-CO-C9-NH2
CAS:(S,R,S)-AHPC-CO-C9-NH2 is a Von Hippel-Lindau (VHL) amino building block utilized in the synthesis of E3 ligase ligands required for PROTACs development.Formula:C32H49N5O4SMolecular weight:599.83HER2-IN-20
<p>HER2-IN-20 (compound 32) is a potent and selective inhibitor of HER2WT and HER2YVMA, with IC50 values of 49 and 42 nM, respectively. It holds potential for research in non-small cell lung cancer (NSCLC).</p>Formula:C30H27ClFN7O2Molecular weight:571.18988Diflufenican
CAS:Diflufenican (M&B 38544) increases the production of phytoene in carrot cell cultures by inducing the inhibition of phytoene desaturase gene expression.Formula:C19H11F5N2O2Purity:99.62%Color and Shape:Odorlessness White SolidMolecular weight:394.297-Bromoheptanoyl chloride
CAS:7-Bromoheptanoyl chloride is the link (ligand) in the formation of PROTACEGFR degrader 9.Formula:C7H12BrClOMolecular weight:227.53Protein kinase inhibitor 7
CAS:Protein kinase inhibitor 7 functions as an inhibitor of protein kinase A (PKA) and protein kinase C (PKC). It impacts the autocrine motility factor (AMF) signaling pathway without affecting cell motility.Formula:C12H15N3O2SMolecular weight:265.33Clomipramine
CAS:<p>Clomipramine treats OCD, depression, chronic pain, and may lower suicide risk in seniors; works by hindering serotonin reuptake.</p>Formula:C19H23ClN2Purity:99.31% - 99.71%Color and Shape:SolidMolecular weight:314.85(S,R,S)-Me-AHPC-amide-C3-alkyne
CAS:<p>(S,R,S)-Me-AHPC-amide-C3-alkyne is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), utilized in the synthesis of JWZ-5-13.</p>Formula:C29H38N4O4SMolecular weight:538.70ORM-5029
ORM-5029 is the first antibody-drug conjugate (ADC) targeting the human epidermal growth factor receptor 2 (HER2), combining the highly potent GSPT1 degrader SMol006 with Pertuzumab. It is applicable in cancer research.Thonzylamine hydrochloride
CAS:Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.Formula:C16H23ClN4OPurity:99.67%Color and Shape:White Crystalline PowderMolecular weight:322.83SAE-IN-2
SAE-IN-2 (compound 6) is a potent inhibitor of sumoylation-activating enzyme (SAE) with an IC50 value of 27.8 nM.Formula:C27H30ClN5O5S2Molecular weight:603.13769MUS81-IN-1
<p>MUS81-IN-1 (compound 23) is an MUS81 inhibitor, utilized in cancer research.</p>Formula:C23H21N3O5Molecular weight:419.14812Platelet aggregation-IN-1
<p>Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.</p>Formula:C18H13N3O4Molecular weight:335.09061Antibacterial agent 226
Antibacterialagent 226 (Compound 7f) is an antibacterial agent effective against Staphylococcus aureus strains, including methicillin-resistant S. aureus, with a MIC of 2 μg/mL. It exhibits cytotoxicity towards HEK293 cells with an IC50 of 1.9 μM.Formula:C24H26F3N3O2Molecular weight:445.19771α-Amylase-IN-7
CAS:<p>α-Amylase-IN-7 (Compound 6e) is an inhibitor of α-Amylase, with an IC50 of 40 μM, indicating its potency. This compound shows potential as an anti-diabetic medication.</p>Formula:C18H15ClN6O2SMolecular weight:414.87Cyproterone
CAS:<p>Cyproterone, an anti-androgen, treats female hirsutism and acne, and is used palliatively in prostate cancer.</p>Formula:C22H27ClO3Color and Shape:SolidMolecular weight:374.9
