TNF
Gli inibitori del fattore di necrosi tumorale (TNF) sono composti che bloccano l'attività del TNF, una citochina coinvolta nell'infiammazione e nella regolazione dell'apoptosi. Il TNF può indurre l'apoptosi in alcuni tipi di cellule mentre promuove la sopravvivenza e l'infiammazione in altri. L'inibizione del TNF è cruciale nel trattamento delle malattie autoimmuni, delle condizioni infiammatorie croniche e di alcuni tipi di cancro. Gli inibitori del TNF aiutano a modulare la risposta immunitaria e a ridurre i danni ai tessuti causati da un'infiammazione eccessiva. Presso CymitQuimica, offriamo una vasta gamma di inibitori del TNF di alta qualità per supportare la tua ricerca in immunologia, infiammazione e apoptosi.
Foram encontrados 49 produtos de "TNF"
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Conatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:145.44 kDaUtomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Fórmula:C17H24N8O3Pureza:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:142.77 kDaUCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Fórmula:C26H25N5OPureza:98.39% - 99.24%Cor e Forma:SolidPeso molecular:423.51Ref: TM-T13951
1mg92,00€2mg133,00€5mg219,00€10mg353,00€25mg602,00€50mg802,00€100mg1.108,00€200mg1.485,00€1mL*10mM (DMSO)245,00€(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Fórmula:C27H39N5O7Pureza:97.61% - 99.72%Cor e Forma:SolidPeso molecular:545.63Varlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Pureza:SDS-PAGE:95% SEC-HPLC:98.65%Cor e Forma:LiquidPeso molecular:146 kDaEJMC-1
CAS:EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.Fórmula:C17H11ClN2O4SPureza:98.38%Cor e Forma:SolidPeso molecular:374.8DSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.Fórmula:C66H108F3N15O28Cor e Forma:SolidPeso molecular:1616.64TNF-α Antagonist
CAS:TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFórmula:C58H71N11O15S2Cor e Forma:SolidPeso molecular:1226.39Dapirolizumab
Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.Pureza:>95%Cor e Forma:LiquidPeso molecular:150 kDaRO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Cor e Forma:Odour LiquidKGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Fórmula:C84H129N21O22SCor e Forma:SolidPeso molecular:1817.12TNF-α (46-65), human
CAS:Human TNF alpha (46-65) peptide.Fórmula:C110H172N24O30Pureza:98%Cor e Forma:SolidPeso molecular:2310.69Pamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Pureza:95%Cor e Forma:LiquidPeso molecular:145.20 kDaTengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Cor e Forma:LiquidAcetyl tetrapeptide-2
CAS:Acetyl tetrapeptide-2 is a skin conditioner, by soothing and nourishing the skin through similar mechanisms as other peptides.Fórmula:C26H39N5O9Pureza:98%Cor e Forma:SolidPeso molecular:565.62TNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Fórmula:C17H14O4Pureza:99.21%Cor e Forma:SoildPeso molecular:282.29Ragifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.
Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Cor e Forma:LiquidPeso molecular:146.46 kDaMK-4166
MK-4166 is a humanized IgG1 agonistic monoclonal antibody targeting GITR. It is capable of enhancing the proliferation of both naive T lymphocytes and tumor-infiltrating T lymphocytes.HS-243
CAS:HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
Fórmula:C17H16N4O3Pureza:98.62%Cor e Forma:SolidPeso molecular:324.33TNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.Pureza:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Cor e Forma:Lyophilized PowderPeso molecular:16 KDa (reducing condition)Ref: TM-TMPJ-00124
1mg1.017,00€5µg42,00€10µg59,00€20µg87,00€50µg130,00€100µg210,00€200µg354,00€500µg709,00€
