Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(94 produtos)
- CDK(500 produtos)
- Ciclo celular/Parada(4 produtos)
- Chk(42 produtos)
- DYRK(48 produtos)
- Dinamina(23 produtos)
- Ferroptose(215 produtos)
- HSP(169 produtos)
- Integrinas(224 produtos)
- Cinesina(66 produtos)
- LIM Quinase(19 produtos)
- Microtúbulo associado(261 produtos)
- PKC(102 produtos)
- PLK(28 produtos)
- ROCK(70 produtos)
- Rho(2 produtos)
- Wee1(15 produtos)
- c-Myc(69 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"
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PD 407824
CAS:<p>PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).</p>Fórmula:C20H12N2O3Pureza:98.02%Cor e Forma:SolidPeso molecular:328.322'-O-Methyl-5-iodouridine
CAS:<p>2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a</p>Fórmula:C10H13IN2O6Pureza:99.89%Cor e Forma:SolidPeso molecular:384.12TG003
CAS:<p>TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.</p>Fórmula:C13H15NO2SPureza:99.46%Cor e Forma:SolidPeso molecular:249.33Talotrexin
CAS:<p>Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.</p>Fórmula:C27H27N9O6Cor e Forma:SolidPeso molecular:573.56kb-NB77-78
CAS:<p>kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).</p>Fórmula:C18H25NO3SiPureza:99.54%Cor e Forma:SolidPeso molecular:331.48Rabusertib
CAS:<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Fórmula:C18H22BrN5O3Pureza:98.86% - 99.87%Cor e Forma:SolidPeso molecular:436.3Trilaciclib
CAS:<p>Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.</p>Fórmula:C24H30N8OPureza:99.624%Cor e Forma:SolidPeso molecular:446.55Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Cor e Forma:SolidPeso molecular:516.65Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Fórmula:C26H32ClN7O4SCor e Forma:SolidPeso molecular:574.09NSC 617145
CAS:<p>NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent</p>Fórmula:C13H10Cl4N2O4Pureza:99.72%Cor e Forma:SolidPeso molecular:400.04GDC0575 monohydrochloride
CAS:<p>GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.</p>Fórmula:C16H21BrClN5OPureza:97.85%Cor e Forma:SolidPeso molecular:414.73AT-9283 HCl
CAS:<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Fórmula:C19H24ClN7O2Cor e Forma:SolidPeso molecular:417.89Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Fórmula:C26H26N3NaO5SCor e Forma:SolidPeso molecular:515.56Phosphonoformic acid trisodium salt hexa
CAS:<p>Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.</p>Fórmula:CH12Na3O11PPureza:98%Cor e Forma:SolidPeso molecular:300.03E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Cor e Forma:SolidPeso molecular:336.37EN4
CAS:<p>EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.</p>Fórmula:C25H24N2O4Pureza:98.51%Cor e Forma:SolidPeso molecular:416.47CKI-7 free base
CAS:<p>CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Fórmula:C11H12ClN3O2SCor e Forma:SolidPeso molecular:285.75MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Fórmula:C15H9NO3Pureza:98.6%Cor e Forma:SolidPeso molecular:251.24TH-263
CAS:<p>TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.</p>Fórmula:C21H20N2O3SPureza:99.54%Cor e Forma:SolidPeso molecular:380.46iRGD peptide
CAS:<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Fórmula:C35H57N13O14S2Pureza:98.77%Cor e Forma:SolidPeso molecular:948.04Orbofiban
CAS:<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Fórmula:C17H23N5O4Cor e Forma:SolidPeso molecular:361.4APTO-253 HCl
CAS:<p>APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.</p>Fórmula:C22H15ClFN5Cor e Forma:SolidPeso molecular:403.84HA-100 hydrochloride
CAS:<p>HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.</p>Fórmula:C13H16ClN3O2SCor e Forma:SolidPeso molecular:313.8BMH-21
CAS:<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Cor e Forma:SolidPeso molecular:360.41S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Fórmula:C22H21NO2SPureza:97.02%Cor e Forma:Almost White To Light Yellow Granular PowderPeso molecular:363.47Apcin
CAS:<p>Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.</p>Fórmula:C13H14Cl3N7O4Pureza:96.74%Cor e Forma:SolidPeso molecular:438.65CHR-6494
CAS:<p>CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).</p>Fórmula:C16H16N6Pureza:98.78%Cor e Forma:SolidPeso molecular:292.34Palmatine chloride
CAS:<p>Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.</p>Fórmula:C21H22ClNO4Pureza:97.9% - 99.47%Cor e Forma:SolidPeso molecular:387.857Datelliptium chloride hydrochloride
CAS:<p>Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.</p>Fórmula:C23H29Cl2N3OPureza:99.46%Cor e Forma:SolidPeso molecular:434.4CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Cor e Forma:SolidPeso molecular:551.48AZD-7762
CAS:<p>AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.</p>Fórmula:C17H19FN4O2SPureza:98.96% - 99.19%Cor e Forma:SolidPeso molecular:362.42Netarsudil free base
CAS:<p>Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.</p>Fórmula:C28H27N3O3Cor e Forma:SolidPeso molecular:453.53NG 52
CAS:<p>NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.</p>Fórmula:C16H19ClN6OPureza:98% - 99.34%Cor e Forma:SolidPeso molecular:346.81LY3143921
CAS:<p>LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].</p>Fórmula:C16H12FN5OCor e Forma:SolidPeso molecular:309.3RCM-1
CAS:<p>RCM-1 is an inhibitor of FOXM1.</p>Fórmula:C20H12N2OS4Pureza:98.08%Cor e Forma:SolidPeso molecular:424.58IRE1α kinase-IN-1
CAS:<p>IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.</p>Fórmula:C26H26ClFN8Pureza:99.18%Cor e Forma:SolidPeso molecular:504.99Levomefolate calcium
CAS:<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Fórmula:C20H23CaN7O6Pureza:97.35%Cor e Forma:Off-White To Pale Yellow SolidPeso molecular:497.52Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Fórmula:C28H26Cl2N4O5Pureza:99.26% - 99.72%Cor e Forma:SolidPeso molecular:569.44Brr2-IN-3
CAS:<p>Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.</p>Fórmula:C24H20N4O3SPureza:99.26%Cor e Forma:SolidPeso molecular:444.51Avotaciclib trihydrochloride
CAS:<p>Avotaciclib trihydrochloride (BEY1107) is an oral CDK1 inhibitor targeting advanced pancreatic cancer.</p>Fórmula:C13H14Cl3N7OPureza:99%Cor e Forma:SolidPeso molecular:390.653'-Deoxyguanosine
CAS:<p>3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.</p>Fórmula:C10H13N5O4Pureza:98.85% - 98.96%Cor e Forma:SolidPeso molecular:267.24Tempo
CAS:<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Fórmula:C9H18NOPureza:98.35%Cor e Forma:Orange Crystals Or PowderPeso molecular:156.25AI-10-49
CAS:<p>AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.</p>Fórmula:C30H22F6N6O5Pureza:97.14%Cor e Forma:SolidPeso molecular:660.526-Thioinosine
CAS:<p>6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.</p>Fórmula:C10H12N4O4SPureza:97.74%Cor e Forma:SolidPeso molecular:284.29Deoxythymidine triphosphate
CAS:<p>Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.</p>Fórmula:C10H14N2Na3O14P3Pureza:99.78%Cor e Forma:White Amorphous PowderPeso molecular:548.11PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Fórmula:C18H21Cl3N4OPureza:99.5%Cor e Forma:SolidPeso molecular:415.75Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Cor e Forma:SolidPeso molecular:375.37Pyridostatin hydrochloride
CAS:<p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>Fórmula:C31H37Cl5N8O5Cor e Forma:SolidPeso molecular:778.94BMS-8
CAS:<p>BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.</p>Fórmula:C27H28BrNO3Pureza:98.88%Cor e Forma:SolidPeso molecular:494.42Mps1-IN-1 dihydrochloride
CAS:<p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>Fórmula:C28H35Cl2N5O4SCor e Forma:SolidPeso molecular:608.58UNC10217938A
CAS:<p>UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects.</p>Fórmula:C26H28N6O2Pureza:98%Cor e Forma:SolidPeso molecular:456.54LY3405105
CAS:<p>LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-</p>Fórmula:C26H39N7O3Pureza:99.66%Cor e Forma:SolidPeso molecular:497.63Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Fórmula:C26H30FN7O3Pureza:98.43% - 99.29%Cor e Forma:SolidPeso molecular:507.56N6,N6-Dimethyladenosine
CAS:<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Fórmula:C12H17N5O4Pureza:98.79%Cor e Forma:White PowderPeso molecular:295.29Proguanil
CAS:<p>Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .</p>Fórmula:C11H16ClN5Pureza:99.6%Cor e Forma:SolidPeso molecular:253.73FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Fórmula:C17H18FN3SPureza:98.61%Cor e Forma:SolidPeso molecular:315.41NVP-LCQ195
CAS:<p>NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).</p>Fórmula:C17H19Cl2N5O4SPureza:99.56% - 99.85%Cor e Forma:SolidPeso molecular:460.33JSH-150
CAS:<p>JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).</p>Fórmula:C24H33ClN6O2SPureza:99.96% - 99.96%Cor e Forma:SolidPeso molecular:505.08Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Fórmula:C27H40N8O7Pureza:98% - 99.8%Cor e Forma:SolidPeso molecular:588.66Atuveciclib
CAS:<p>Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.</p>Fórmula:C18H18FN5O2SPureza:98.8%Cor e Forma:SolidPeso molecular:387.432-Chloroadenosine
CAS:<p>2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively</p>Fórmula:C10H12ClN5O4Pureza:99.23%Cor e Forma:White PowderPeso molecular:301.69Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Fórmula:C29H29FN3O9PPureza:95.87%Cor e Forma:SolidPeso molecular:613.53GSK461364
CAS:<p>GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.</p>Fórmula:C27H28F3N5O2SPureza:99% - 99.73%Cor e Forma:SolidPeso molecular:543.6ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Cor e Forma:SolidPeso molecular:533.593-AP
CAS:<p>3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).</p>Fórmula:C7H9N5SPureza:97.33% - 99.87%Cor e Forma:SolidPeso molecular:195.24CW-069
CAS:<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Cor e Forma:SolidPeso molecular:500.33CCG-203971
CAS:<p>CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.</p>Fórmula:C23H21ClN2O3Pureza:98.82% - 99.50%Cor e Forma:SolidPeso molecular:408.88SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Fórmula:C25H20FN7OPureza:97.82%Cor e Forma:SolidPeso molecular:453.47LY2880070
CAS:<p>LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.</p>Fórmula:C19H23N7O2Pureza:99.77%Cor e Forma:SolidPeso molecular:381.43BMS-1001
CAS:<p>BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).</p>Fórmula:C35H34N2O7Pureza:98.43%Cor e Forma:SolidPeso molecular:594.7WNK-IN-11
CAS:<p>WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)</p>Fórmula:C21H21Cl2N5OSPureza:98.32%Cor e Forma:SolidPeso molecular:462.4Bractoppin
CAS:<p>Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits</p>Fórmula:C25H23FN4OPureza:98.38%Cor e Forma:SolidPeso molecular:414.47DMT-2′Fluoro-dU Phosphoramidite
CAS:<p>DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.</p>Fórmula:C39H46FN4O8PPureza:99.5%Cor e Forma:SolidPeso molecular:748.78BMS-5
CAS:<p>BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.</p>Fórmula:C17H14Cl2F2N4OSPureza:98.01% - 99.88%Cor e Forma:SolidPeso molecular:431.292′-Deoxy-2′-fluoroguanosine
CAS:<p>2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).</p>Fórmula:C10H12FN5O4Pureza:99.89%Cor e Forma:SolidPeso molecular:285.23AZD-5597
CAS:<p>AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent</p>Fórmula:C23H28FN7OPureza:98.01%Cor e Forma:SolidPeso molecular:437.51WR99210 hydrochloride(47326-86-3 free base)
CAS:<p>WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.</p>Fórmula:C14H19Cl4N5O2Pureza:97.77% - 99.8%Cor e Forma:SolidPeso molecular:431.14Saccharin 1-methylimidazole
CAS:<p>Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.</p>Fórmula:C7H5NO3S·C4H6N2Pureza:98.21%Cor e Forma:SolidPeso molecular:265.29LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Fórmula:C23H29ClN8OPureza:100%Cor e Forma:SolidPeso molecular:469.02Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Cor e Forma:SolidPeso molecular:517.06Bonafton
CAS:<p>Bonafton (Bonaphthone) is an antiviral agent.</p>Fórmula:C10H5BrO2Pureza:97.16%Cor e Forma:SolidPeso molecular:237.053-Deazauridine
CAS:<p>3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.</p>Fórmula:C10H13NO6Pureza:99.86%Cor e Forma:SolidPeso molecular:243.21Calcium N5-methyltetrahydrofolate
CAS:<p>Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and</p>Fórmula:C20H23CaN7O6Pureza:99.41%Cor e Forma:SolidPeso molecular:497.51CC-671
CAS:<p>CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.</p>Fórmula:C28H28N6O4Pureza:98.66% - 98.8%Cor e Forma:SolidPeso molecular:512.56Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Fórmula:C14H23F3N6O8Pureza:99.2% - ≥98%Cor e Forma:SolidPeso molecular:460.36Trifluridine/tipiracil hydrochloride mixture
CAS:<p>Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a</p>Fórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Cor e Forma:SolidPeso molecular:871.53Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Cor e Forma:SolidPeso molecular:355.36EHT 1864 2HCl
CAS:<p>EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.</p>Fórmula:C25H29Cl2F3N2O4SPureza:98.39% - 99.42%Cor e Forma:SolidPeso molecular:581.47Danofloxacin
CAS:<p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>Fórmula:C19H20FN3O3Pureza:99.77% - 99.8%Cor e Forma:SolidPeso molecular:357.38GPRP acetate (67869-62-9 free base)
CAS:<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Fórmula:C20H35N7O7Pureza:>99.99%Cor e Forma:SolidPeso molecular:485.536-O-Methyl Guanosine
CAS:<p>6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.</p>Fórmula:C11H15N5O5Pureza:97.5%Cor e Forma:SolidPeso molecular:297.27MLN0905
CAS:<p>MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).</p>Fórmula:C24H25F3N6SPureza:97.17% - 98%Cor e Forma:SolidPeso molecular:486.56Levoleucovorin Calcium
CAS:<p>Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.</p>Fórmula:C20H21N7O7·CaPureza:99.07% - ≥98%Cor e Forma:White Crystalline PowderPeso molecular:511.5BMS-3
CAS:<p>BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.</p>Fórmula:C17H12Cl2F2N4OSPureza:99.31% - 99.81%Cor e Forma:SolidPeso molecular:429.27Fanotaprim
CAS:<p>Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.</p>Fórmula:C19H22N8OPureza:98.1%Cor e Forma:SolidPeso molecular:378.43TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Fórmula:C24H21Cl2NO5Pureza:98.98%Cor e Forma:SolidPeso molecular:474.33EOAI3402143
CAS:<p>EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.</p>Fórmula:C25H28Cl2N4O3Pureza:99.6%Cor e Forma:SolidPeso molecular:503.42LY3177833
CAS:<p>LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)</p>Fórmula:C16H12FN5OPureza:99.87%Cor e Forma:SolidPeso molecular:309.3LXW7
CAS:<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Fórmula:C29H48N12O12S2Pureza:>99.99%Cor e Forma:SolidPeso molecular:820.89AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Cor e Forma:SolidPeso molecular:381.43
