Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(116 produtos)
- CDK(547 produtos)
- Ciclo celular/Parada(5 produtos)
- Chk(48 produtos)
- DYRK(46 produtos)
- Dinamina(27 produtos)
- Ferroptose(227 produtos)
- HSP(180 produtos)
- Integrinas(276 produtos)
- Cinesina(87 produtos)
- LIM Quinase(21 produtos)
- Microtúbulo associado(273 produtos)
- PKC(127 produtos)
- PLK(25 produtos)
- ROCK(61 produtos)
- Rho(6 produtos)
- Wee1(14 produtos)
- c-Myc(77 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3923 produtos de "Ciclo celular/Ponto de verificação"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
4-Amino-5-cyano-1-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine
CAS:Nucleoside Derivatives - 7-Deaza-purine nucleosides; Scaffolds and TemplatesFórmula:C12H13N5O4Cor e Forma:SolidPeso molecular:291.26Ref: TM-TNU0271
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar4-Deoxy-xylo-uridine
CAS:Nucleoside Derivatives - Xylo-nucleosides; 4-Deoxy pyrimidine nucleosidesFórmula:C9H12N2O5Cor e Forma:SolidPeso molecular:228.2Ref: TM-TNU1366
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-2'-fluoro-3',5'-bis-O-TBDMS-uridine
CAS:Nucleoside Derivatives –Fluoro-modified nucleosides；Fórmula:C21H39FN2O5Si2Cor e Forma:SolidPeso molecular:474.71Ref: TM-TNU1512
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS:4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - Halo-nucleoside, 7-Deaza-purine nucleoside.Fórmula:C11H11ClIN3O3Cor e Forma:SolidPeso molecular:395.58Ref: TM-TNU1025
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN4-Desmethyl-N5-Methyl wyosine
CAS:N4-Desmethyl-N5-Methyl wyosine is a Nucleoside Derivative - Bi-/Tri-cyclic nucleoside; naturally modified ribo-nucleoside.Fórmula:C14H17N5O5Cor e Forma:SolidPeso molecular:335.32Ref: TM-TNU0179
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-[6-(Diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hexofuranosyl]uracil
Nucleoside Derivatives - Phosphorus-containing nucleosides; 2’-Modified nucleosides; 5’-Modified nucleosidesCor e Forma:SoildRef: TM-TNU1286
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1,2'-O-Dimethyl guanosine
CAS:1,2'-O-Dimethyl guanosine is a Nucleoside Derivative - 3'-Modified nucleoside, N-Methylated/ alkylated nucleoside.Fórmula:C12H17N5O5Cor e Forma:SolidPeso molecular:311.29Ref: TM-TNU0572
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarIsocytidine
CAS:Nucleosides - isocytidine derivativeFórmula:C9H13N3O5Cor e Forma:SolidPeso molecular:243.22Ref: TM-TNU0049
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2',3',5'-Tri-O-benzoyl-5-methoxyuridine
CAS:2',3',5'-Tri-O-benzoyl-5-methoxyuridine is a 5-Modified Pyrimidine Nucleoside.Fórmula:C31H26N2O10Cor e Forma:SolidPeso molecular:586.55Ref: TM-TNU0806
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2-Methoxy-9-(β-D-ribofuranosyl)purine
CAS:Nucleoside Derivatives - 6-De-aminopurine nucleosides, 2-Modified purine nucleosidesFórmula:C11H14N4O5Cor e Forma:SolidPeso molecular:282.25Ref: TM-TNU1109
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-2'-fluoro-N1-methyl inosine
CAS:Nucleoside Derivatives - 2’-Modified nucleosides, Fluoro-modified nucleosides, N-Methylated /alkylated nucleosidesFórmula:C11H13FN4O4Cor e Forma:SolidPeso molecular:284.24Ref: TM-TNU0548
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Chloro-2'-deoxyuridine
CAS:2'-Chloro-2'-deoxyuridine is a Halo-nucleoside.Fórmula:C9H11ClN2O5Cor e Forma:SolidPeso molecular:262.65Ref: TM-TNU0073
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-N6,N6-dimethyladenosine
CAS:2'-Deoxy-N6,N6-dimethyladenosine is a Nucleoside Derivative - 6-Modified purine nucleoside.Fórmula:C12H17N5O3Cor e Forma:SolidPeso molecular:279.3Ref: TM-TNU1369
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-(b-D-Xylofuranosyl)-5-methylcytosine
CAS:Nucleoside Derivatives –5-Modified pyrimidine nucleosides；Xylo-nucleosidesFórmula:C10H15N3O5Cor e Forma:SolidPeso molecular:257.24Ref: TM-TNU0521
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3'-O-Methyl-5-methyluridine
CAS:3'-O-Methyl-5-methyluridine is a Nucleoside Derivative - 3'-Modified nucleoside.Fórmula:C11H16N2O6Cor e Forma:SolidPeso molecular:272.25Ref: TM-TNU1393
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine
CAS:Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosidesFórmula:C14H20N6O6Cor e Forma:SolidPeso molecular:368.35Ref: TM-TNU0387
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine
CAS:6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine is a 2'-C-Methyl nucleoside; Halo-nucleoside.Fórmula:C32H25ClN4O7Cor e Forma:SolidPeso molecular:613.02Ref: TM-TNU0772
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-(b-D-Xylofuranosyl)-5-trifluoromethyluracil
1-(b-D-Xylofuranosyl)-5-trifluoromethyluracil is a Nucleoside Derivative - Xylo-nucleoside, Fluoro-modified nucleoside, 5-Modified pyrimidine nucleoside.Cor e Forma:SoildRef: TM-TNU1483
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2-Cyanoadenosine
CAS:Nucleoside Derivatives - 2’-Modified purine nucleosidesFórmula:C11H12N6O4Cor e Forma:SolidPeso molecular:292.25Ref: TM-TNU0296
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar5-Iodoarabinouridine
CAS:5-Iodoarabinouridine is a Halo-nucleoside; Arabino-nucleoside.Fórmula:C9H11IN2O6Cor e Forma:SolidPeso molecular:370.1Ref: TM-TNU0784
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN1-Ethylpseudouridine
CAS:N1-Ethylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Methylated nucleoside.Fórmula:C11H16N2O6Cor e Forma:SolidPeso molecular:272.25Ref: TM-TNU0062
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine
CAS:2'-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a Nucleoside Derivative - 6-Modified purine nucleoside.Fórmula:C18H20N6O6Cor e Forma:SolidPeso molecular:416.39Ref: TM-TNU1005
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarKS15
CAS:KS15 is a cryptochrome (CRY) inhibitor that promotes G1 cell cycle arrest, enhances drug sensitivity in MCF-7 cells, antitumour against human breast cancer.Fórmula:C20H22BrNO4Cor e Forma:SolidPeso molecular:420.33'-O-DMTr-thymidine 5'-CE phosphoramidite
CAS:3'-O-DMTr-thymidine 5'-CE phosphoramidite (2'-OMe-U Phosphoramidite) is a purine nucleoside analog and phosphoramidite derivative .Fórmula:C40H49N4O8PPureza:99.42%Cor e Forma:SolidPeso molecular:744.81Lifitegrast sodium
CAS:Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Fórmula:C29H23Cl2N2NaO7SPureza:99.33%Cor e Forma:SolidPeso molecular:637.46GP-82996
CAS:GP-82996 (CINK4) inhibits CDK4/6; IC50s: 1.5 μM (CDK4/D1), 5.6 μM (CDK6/D1), 25 μM (Cdk5/p35); triggers U2OS cancer cell apoptosis.Fórmula:C27H32N6OPureza:99.94%Cor e Forma:SolidPeso molecular:456.58HDGFRP2/PSIP1-IN-1
CAS:Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual inhibitor targeting the PWWP domains of Hepatoma-derived Growth Factor Related Protein 2 (HDGFRP2) and its homologue PSIP1. This compound effectively hinders the occurrence and progression of Diffuse Intrinsic Pontine Glioma (DIPG). It demonstrates binding affinity with a Kd value of 7 μM for HDGFRP2, indicative of its efficient ligand efficacy at 0.47. Additionally, Compound BPP exhibits a Kd value of 27 μM when binding to the PSIP1 PWWP domain, and a Kd value of 14 μM against HDGFRP3, confirming its potency as an inhibitor within the HDGFRP2 PWWP subfamily.Fórmula:C8H6BrN3Cor e Forma:SolidPeso molecular:224.06Napropamide
CAS:Napropamide is an acetamide herbicide that inhibits root growth to control annual grasses and broadleaf weeds.Fórmula:C17H21NO2Pureza:99.14%Cor e Forma:Colorless Crystals; (Tech Brown Solid) White-Like CrystalPeso molecular:271.35N-6-Furfurylguanosine
CAS:N-6-Furfurylguanosine (kinetin riboside) is a purine nucleoside analog with cytotoxicity, inhibiting the growth of cancer cells.Fórmula:C15H18N6O5Pureza:99.58%Cor e Forma:SolidPeso molecular:362.345,6-Dihydrothymidine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Fórmula:C10H16N2O5Pureza:99.90%Cor e Forma:SolidPeso molecular:244.24(S)-GNA-T-phosphoramidite
CAS:(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.Fórmula:C38H47N4O7PPureza:97.08%Cor e Forma:SolidPeso molecular:702.782'-O-Methyl-5-methyl uridine
CAS:2'-O-Methyl-5-methyl uridine is a 2'-O-Methyl nucleoside.Fórmula:C11H16N2O6Cor e Forma:SolidPeso molecular:272.25Ref: TM-TNU0716
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar5-Aza-7-deazaguanine
CAS:5-Aza-7-deazaguanine is a non-natural substituted nucleobase with potential antiviral activity, used in cancer and bacterial infection research.Fórmula:C5H5N5OPureza:98.87%Cor e Forma:SolidPeso molecular:151.13Yuanhuacine
CAS:Gnidilatidin is a biochemical.Fórmula:C37H44O10Cor e Forma:SolidPeso molecular:648.7492'-O-Methyl isocytidine
CAS:Isocytidine derivative; 2’-O-Methyl nucleosideFórmula:C10H15N3O5Cor e Forma:SolidPeso molecular:257.24Ref: TM-TNU0050
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar6-Methylmercaptopurine riboside
CAS:6-Methylmercaptopurine riboside is a purine nucleoside analogue applicable to biochemical experiments and drug synthesis studies.Fórmula:C11H14N4O4SCor e Forma:SolidPeso molecular:298.32TCRS-417
CAS:TCRS-417 (T417) inhibits PBX1-DNA interaction in mammalian cells or cell clusters, used in autoimmune and neurodegenerative disease research.Fórmula:C25H19FN2O5Cor e Forma:SolidPeso molecular:446.43N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine
CAS:Nucleoside Derivatives - 2’-Modified nucleoside, Protected nucleosides with NH2/OH open; Ready for phosphorylationFórmula:C41H43N3O9Cor e Forma:SolidPeso molecular:721.79Ref: TM-TNU1115
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar(S)-GNA-G(iBu) phosphoramidite
CAS:(S)-GNA-G(iBu) phosphoramidite is a Nucleoside Derivative - Acyclic nucleoside;Nucleoside Phosphoramidite.Fórmula:C42H52N7O7PCor e Forma:SolidPeso molecular:797.88Ref: TM-TNU1440
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarX5050
CAS:X5050 is a REST inhibitor, with an EC 50 of 2.1 μM.Fórmula:C17H15N3O3Cor e Forma:SolidPeso molecular:309.325Cytidine (Standard)
CAS:Cytidine (Standard) is the standard substance of Cytidine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.Fórmula:C9H13N3O5Cor e Forma:Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:243.225-Bromocytidine
CAS:5-Bromocytidine is a nucleoside analog that is a key disinfection by-product of drinking water and may interfere with nucleic acid synthesis.Fórmula:C9H12BrN3O5Pureza:99.63%Cor e Forma:SolidPeso molecular:322.115'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine
CAS:5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine is a Nucleoside Derivative - 2'-Modified nucleoside; Protected nucleoside with NH2/OH open;Fórmula:C34H38N2O9Cor e Forma:SolidPeso molecular:618.67Ref: TM-TNU1094
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarCeftriaxone Sodium
CAS:Ceftriaxone Sodium is a sporotaxin antibiotic that inhibits GSK3β and Aurora B. It is used in the study of sepsis and infective endocarditis.Fórmula:C18H17N8NaO7S3Cor e Forma:SolidPeso molecular:576.5622'-Amino-2'-deoxy-b-D-arabino-5-methyl uridine
CAS:2'-Amino-2'-deoxy-b-D-arabino-5-methyl uridine is a purine nucleoside analog with potential antitumor activity.Fórmula:C10H15N3O5Pureza:96.76%Cor e Forma:SolidPeso molecular:257.24VP-U-6
CAS:VP-U-6 is a Nucleoside Phosphoramidite; Nucleoside Derivative - Phosphorus-containing nucleotide; 5'-Modified nucleoside.Fórmula:C24H40N4O9P2Cor e Forma:SolidPeso molecular:590.54Ref: TM-TNU1009
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarDOTA-cyclo(RGDfK)
CAS:DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.Fórmula:C43H67N13O14Cor e Forma:SoildPeso molecular:990.078-Hydroxyadenosine
CAS:8-Hydroxyadenosine (8-Oxoadenosine) is a purine nucleoside found in Torula yeast RNA.Fórmula:C10H13N5O5Pureza:99.71%Cor e Forma:SolidPeso molecular:283.24Verosudil
CAS:Verosudil (AR-12286), a ROCK1/2 inhibitor (Ki: 2 nM), lowers intraocular pressure in mice by enhancing aqueous outflow.Fórmula:C17H17N3O2SPureza:99.68%Cor e Forma:SolidPeso molecular:327.4Ref: TM-T60924
1mg55,00€5mg147,00€1mL*10mM (DMSO)161,00€10mg231,00€25mg370,00€50mg522,00€100mg692,00€A-674563
CAS:A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.Fórmula:C22H22N4OPureza:99.21%Cor e Forma:SolidPeso molecular:358.44GSK269962A hydrochloride
CAS:GSK269962A hydrochloride (GSK 269962 hydrochloride) is a ROCK inhibitor with anti-inflammatory and vasodilatory effects and inhibits ROCK1 and ROCK2.Fórmula:C29H31ClN8O5Cor e Forma:SolidPeso molecular:607.06TG-693
CAS:TG-693, Oral CLK1 inhibitor, promotes exon 31 skipping of dystrophin gene, inhibits CLK1 substrate phosphorylation, for Duchenne muscular dystrophy.Fórmula:C12H9N3Pureza:99.81%Cor e Forma:SolidPeso molecular:195.23GPRP
CAS:GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.Fórmula:C18H31N7O5Cor e Forma:White To Off-White PowderPeso molecular:425.48STD1T
CAS:STD1T is a USP2a inhibitor with anticancer activity that reduces levels of the cell cycle protein D1 protein in HCT116 colon cancer cells.Fórmula:C19H19N3O4S2Pureza:98.77%Cor e Forma:SolidPeso molecular:417.5PROTAC CDK9 Degrader-1
CAS:PROTAC CDK9 Degrader-1 is a selective PROTAC-based CDK9 degrader, composed of a Cereblon ligand and a CDK ligand.Fórmula:C33H35N5O7Pureza:95.1%Cor e Forma:SolidPeso molecular:613.66USP8-IN-1
CAS:USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 μM [1].Fórmula:C18H21N5O3SPureza:99.07%Cor e Forma:SoildPeso molecular:387.46Ref: TM-T60146
1mg84,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg250,00€25mg439,00€50mg620,00€100mg893,00€Belumosudil mesylate
CAS:Belumosudil mesylate (KD025 mesylate) is a ROCK2 inhibitor with antifibrotic activity, and can be used in chronic graft-versus-host disease research.Fórmula:C27H28N6O5SPureza:98.73%Cor e Forma:SolidPeso molecular:548.61Ref: TM-T39555
1mg34,00€2mg46,00€5mg71,00€1mL*10mM (DMSO)85,00€10mg96,00€25mg155,00€50mg230,00€100mg353,00€200mg517,00€Cotosudil
CAS:Cotosudil is a ROCK kinase inhibitor with antihypertensive activity used to treat or prevent neurodegenerative diseases.Fórmula:C16H21N3O2SPureza:98.41%Cor e Forma:SolidPeso molecular:319.42Maleic hydrazide
CAS:Maleic hydrazide is a plant germination inhibitor that participates in nucleic acid metabolism pathways ,inhibiting cell division in the apical meristem.Fórmula:C4H4N2O2Pureza:98.4%Cor e Forma:Crystals From Water Maleic Hydrazide Is An Odorless White Solid Sinks In Water (Uscg 1999)Peso molecular:112.09N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
CAS:N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity.Fórmula:C47H52N7O7PPureza:97.36%Cor e Forma:SolidPeso molecular:857.932'-O-Methylinosine
CAS:2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally bioavailable purine nucleoside analog with antihypertensive activity.Fórmula:C11H14N4O5Pureza:99.88%Cor e Forma:SolidPeso molecular:282.252',5-Difluoro-2'-deoxy-1-arabinosyluracil
CAS:2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepilepticFórmula:C9H10F2N2O5Pureza:99.99%Cor e Forma:SolidPeso molecular:264.18NU6102
CAS:NU6102 is a CDK2 inhibitor with antitumor activity against CDK1/cyclinB, CDK1/CDK2, CDK4, DYRK1A , PDK1, and ROCKII, and it can be used to study rectal cancer.Fórmula:C18H22N6O3SPureza:99.76%Cor e Forma:SolidPeso molecular:402.47LDC4297
CAS:LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.Fórmula:C23H28N8OPureza:98.25%Cor e Forma:SolidPeso molecular:432.52GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Fórmula:C20H11Cl2NO4Pureza:98%Cor e Forma:SolidPeso molecular:400.21IRES-C11
CAS:IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.Fórmula:C13H11Cl2NO4Pureza:99.89%Cor e Forma:SolidPeso molecular:316.14Ref: TM-T40419
1mg94,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.674,00€200mg2.242,00€Poloxime
CAS:Poloxime is a hydrolysis product of poloxin and is a non-ATP-competitive Plk1 inhibitor. It also has moderate Plk1 inhibitory activity.Fórmula:C10H13NO2Pureza:98%Cor e Forma:SolidPeso molecular:179.22TAME
CAS:Tosyl-L-Arginine Methyl Ester (TAME (N-4-Tosyl-L-arginine methyl ester)) is an APC inhibitor.Fórmula:C14H22N4O4SPureza:98%Cor e Forma:SolidPeso molecular:342.41Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Fórmula:C29H41F3N8O9Cor e Forma:SolidPeso molecular:702.68Nolatrexed dihydrochloride
CAS:Nolatrexed dihydrochloride (Thymitaq) is a soluble, lipophilic cancer drug that inhibits DNA replication, causing cell cycle arrest and apoptosis.Fórmula:C14H14Cl2N4OSPureza:97.02%Cor e Forma:Tan SolidPeso molecular:357.26CCT244747
CAS:CCT244747 is a potent and selective CHK1 inhibitor oral, ATP-competitive, and cytotoxic, abrogating drug-induced S and G2 blockade and inducing apoptosis .Fórmula:C20H24N8O2Pureza:99.17%Cor e Forma:SolidPeso molecular:408.46Ribociclib hydrochloride
CAS:Ribociclib hydrochloride (LEE011 HCl) is a selective, orally active cyclin-dependent kinase CDK4/6 inhibitor (IC50=10/39 nM) that inhibits proliferation.Fórmula:C23H31ClN8OPureza:99.87%Cor e Forma:SolidPeso molecular:471sAJM589
CAS:sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels and inhibiting the cellular proliferation.Fórmula:C16H10N2OPureza:98%Cor e Forma:SolidPeso molecular:246.26Synucleozid hydrochloride
CAS:Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.Fórmula:C22H21ClN6Pureza:98.13%Cor e Forma:SolidPeso molecular:404.9N,N-Dimethyl-2'-O-methylcytidine
CAS:N,N-Dimethyl-2'-O-methylcytidine (N4, N4, 2'-O-Trimethylcytidine) is a purine nucleoside analogue with anti-cancer activity.Fórmula:C12H19N3O5Pureza:99.62%Cor e Forma:SolidPeso molecular:285.38-Chloroinosine
CAS:8-Chloroinosine is a purine nucleoside analog and a metabolite of the anticancer compound 8-chloro-adenosine.Fórmula:C10H11ClN4O5Pureza:99.37% - 99.56%Cor e Forma:SolidPeso molecular:302.67Kinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Fórmula:C20H16Br2N4O4Pureza:97.24%Cor e Forma:SolidPeso molecular:536.17Ref: TM-T15663
2mg39,00€5mg58,00€1mL*10mM (DMSO)70,00€10mg93,00€25mg150,00€50mg219,00€100mg329,00€200mg494,00€5'-O-DMT-N2-ibu-dG
CAS:5'-O-DMT-N2-ibu-dG is a deoxynucleoside served as a building block in oligonucleotide synthesis, with protecting groups to prevent unwanted reactions.Fórmula:C35H37N5O7Pureza:98.71%Cor e Forma:SolidPeso molecular:639.78-Bromoadenosine
CAS:8-Bromoadenosine is an adenosine derivative. 8-Br-Adenosine inhibitis mitochondrial membrane potential, cytoplasmic Ca²⁺ levels, and RNA and protein synthesis.Fórmula:C10H12BrN5O4Pureza:99.11%Cor e Forma:SolidPeso molecular:346.14NSC 23766
CAS:NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.Fórmula:C24H35N7Pureza:99.49%Cor e Forma:SolidPeso molecular:421.58N2-Isobutyryl-2-deoxyguanosine
CAS:N2-Isobutyryl-2-deoxyguanosine（iBu-dG） is a nucleoside analog that can be used to synthesize oligonucleotides.Fórmula:C14H19N5O5Pureza:97.03%Cor e Forma:SolidPeso molecular:337.33APE1-IN-1
CAS:APE1-IN-1 is a purine/pyrimidine-free endonuclease 1 inhibitor with potential antitumor activity that enhances the toxicity of alkylating agents on cancer cellsFórmula:C19H21N3OS2Pureza:98.5%Cor e Forma:SolidPeso molecular:371.52PD 407824
CAS:PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).Fórmula:C20H12N2O3Pureza:98.02%Cor e Forma:SolidPeso molecular:328.322'-O-Methyl-5-iodouridine
CAS:2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a
Fórmula:C10H13IN2O6Pureza:99.89%Cor e Forma:SolidPeso molecular:384.12TG003
CAS:TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.Fórmula:C13H15NO2SPureza:99.46%Cor e Forma:SolidPeso molecular:249.33Ref: TM-T60367
1mg48,00€5mg92,00€10mg150,00€1mL*10mM (DMSO)167,00€25mg266,00€50mg440,00€100mg530,00€200mg767,00€3-Deazauridine
CAS:3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.Fórmula:C10H13NO6Pureza:99.86%Cor e Forma:SolidPeso molecular:243.21kb-NB77-78
CAS:kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).Fórmula:C18H25NO3SiPureza:99.54%Cor e Forma:SolidPeso molecular:331.48Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Cor e Forma:SolidPeso molecular:355.36Palbociclib Isethionate
CAS:Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。Fórmula:C24H29N7O2·C2H6O4SPureza:99.01% - 99.27%Cor e Forma:SolidPeso molecular:573.66EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Fórmula:C25H29Cl2F3N2O4SPureza:98.39% - 99.42%Cor e Forma:SolidPeso molecular:581.47Bractoppin
CAS:Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibitsFórmula:C25H23FN4OPureza:98.38%Cor e Forma:SolidPeso molecular:414.47Ref: TM-T8873
1mg50,00€5mg99,00€1mL*10mM (DMSO)109,00€10mg158,00€25mg309,00€50mg465,00€100mg697,00€500mg1.404,00€Metoprine
CAS:Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.Fórmula:C11H10Cl2N4Pureza:98.42%Cor e Forma:SolidPeso molecular:269.13AT13148
CAS:AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.Fórmula:C17H16ClN3OPureza:98.04% - ≥95%Cor e Forma:SolidPeso molecular:313.78TH-263
CAS:TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.Fórmula:C21H20N2O3SPureza:99.54%Cor e Forma:SolidPeso molecular:380.46Ref: TM-T19578
2mg34,00€5mg49,00€1mL*10mM (DMSO)54,00€10mg75,00€25mg137,00€50mg192,00€100mg281,00€200mg419,00€Activated Protein C (390-404), human acetate
Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.Fórmula:C93H134N22O25Pureza:99.92%Cor e Forma:SolidPeso molecular:1960.19PFM01
CAS:PFM01 inhibits MRE11 enzyme, steering DSBR towards NHEJ over HR.Fórmula:C14H15NO2S2Pureza:98.68%Cor e Forma:SolidPeso molecular:293.4ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Fórmula:C17H21ClN2O4SPureza:99.33% - 99.45%Cor e Forma:SolidPeso molecular:384.88R-IMPP
CAS:R-IMPP is an inhibitor of PCSK9 translation.Fórmula:C24H27N3O2Pureza:99.47% - 99.85%Cor e Forma:SolidPeso molecular:389.49Ref: TM-T4058
1mg46,00€2mg56,00€1mL*10mM (DMSO)75,00€5mg88,00€10mg140,00€25mg280,00€50mg500,00€100mg718,00€GNE-6640
CAS:GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).Fórmula:C20H18N4OPureza:98.64%Cor e Forma:SolidPeso molecular:330.38Ref: TM-T5461
1mg66,00€2mg96,00€5mg144,00€1mL*10mM (DMSO)158,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€6-Chloropurine riboside
CAS:6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.Fórmula:C10H11ClN4O4Pureza:96.84%Cor e Forma:SoildPeso molecular:286.6700
![4-Amino-5-cyano-1-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTNU0271.webp&w=3840&q=75)
![4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTNU1025.webp&w=3840&q=75)
![1-[6-(Diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hexofuranosyl]uracil](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTNU1286.webp&w=3840&q=75)
![2'-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTNU1005.webp&w=3840&q=75)
