
Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(94 produtos)
- CDK(500 produtos)
- Ciclo celular/Parada(4 produtos)
- Chk(42 produtos)
- DYRK(48 produtos)
- Dinamina(23 produtos)
- Ferroptose(215 produtos)
- HSP(169 produtos)
- Integrinas(224 produtos)
- Cinesina(66 produtos)
- LIM Quinase(19 produtos)
- Microtúbulo associado(261 produtos)
- PKC(102 produtos)
- PLK(28 produtos)
- ROCK(70 produtos)
- Rho(2 produtos)
- Wee1(15 produtos)
- c-Myc(69 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"
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Abemaciclib methanesulfonate
CAS:<p>Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).</p>Fórmula:C27H32F2N8·CH4O3SPureza:98.69% - 99.44%Cor e Forma:SolidPeso molecular:602.7BUR1
CAS:<p>BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.</p>Fórmula:C16H17N5Pureza:90%Cor e Forma:SolidPeso molecular:279.34NSC23005 Sodium
CAS:<p>NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.</p>Fórmula:C13H16NNaO4SPureza:99.64%Cor e Forma:SolidPeso molecular:305.32Monastrol
CAS:<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Cor e Forma:SolidPeso molecular:292.35AUZ 454
CAS:<p>AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.</p>Fórmula:C24H26F3N7O2Pureza:99.59%Cor e Forma:SolidPeso molecular:501.5CX-5461
CAS:<p>CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C27H27N7O2SPureza:95.44% - 99.25%Cor e Forma:SolidPeso molecular:513.61Pipobroman
CAS:<p>Pipobroman (Vercyte) is an alkylating anti-cancer drug effective in PV and ET with low toxicity and thrombosis risk.</p>Fórmula:C10H16Br2N2O2Pureza:97.08%Cor e Forma:SolidPeso molecular:356.05BVDV-IN-1
CAS:<p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>Fórmula:C20H22N4OPureza:98.43%Cor e Forma:SolidPeso molecular:334.41PND-1186
CAS:<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Fórmula:C25H26F3N5O3Pureza:99.14% - 99.75%Cor e Forma:SolidPeso molecular:501.52-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi
CAS:<p>2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate.</p>Fórmula:C6H6N4OPureza:99.21% - 99.42%Cor e Forma:SolidPeso molecular:150.14Myoseverin
CAS:<p>Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.</p>Fórmula:C24H28N6O2Pureza:99.25%Cor e Forma:SolidPeso molecular:432.52OSU-T315
CAS:<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Fórmula:C30H30F3N5OPureza:98.69%Cor e Forma:SolidPeso molecular:533.59HMN-176
CAS:<p>HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).</p>Fórmula:C20H18N2O4SPureza:98.92% - 98.99%Cor e Forma:SolidPeso molecular:382.43PTC-209
CAS:<p>PTC-209 is a potent and selective BMI-1 inhibitor.</p>Fórmula:C17H13Br2N5OSPureza:99.43% - 99.887%Cor e Forma:SolidPeso molecular:495.19Antitumor agent-152
CAS:<p>Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.</p>Fórmula:C17H19N5O2S2Pureza:95.00%Cor e Forma:SolidPeso molecular:389.5TC-E 5003
CAS:<p>TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.</p>Fórmula:C16H14Cl2N2O4SPureza:97.01%Cor e Forma:SolidPeso molecular:401.26PHA-680632
CAS:<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Fórmula:C28H35N7O2Pureza:98.2%Cor e Forma:SolidPeso molecular:501.62MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Fórmula:C20H19ClFN5OSPureza:99.09% - 99.79%Cor e Forma:SolidPeso molecular:431.91Purvalanol B
CAS:<p>Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)</p>Fórmula:C20H25ClN6O3Pureza:98.95%Cor e Forma:SolidPeso molecular:432.9C/EBPα inducer 1
CAS:<p>C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via</p>Fórmula:C20H12FN3O4Pureza:98.99%Cor e Forma:SolidPeso molecular:377.33VPC-80051 racemate
CAS:<p>VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.</p>Fórmula:C16H13F2N3OPureza:97.36%Cor e Forma:SolidPeso molecular:301.29HALOFUGINONE LACTATE
CAS:<p>HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.</p>Fórmula:C19H23BrClN3O6Pureza:99.70% - 99.96%Cor e Forma:SolidPeso molecular:504.8WEE1-IN-3
CAS:<p>WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.</p>Fórmula:C28H31N7O2Pureza:98.33%Cor e Forma:SolidPeso molecular:497.59CB-6644
CAS:<p>CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.</p>Fórmula:C29H34ClFN4O5Pureza:96.33% - 99.85%Cor e Forma:SolidPeso molecular:573.062-Chloropyrazine
CAS:<p>2-Chloropyrazine is used in chemical industry.</p>Fórmula:C4H3ClN2Pureza:98.98% - 99.89%Cor e Forma:Clear Colorless To Yellowish LiquidPeso molecular:114.53ARQ 621
CAS:<p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>Fórmula:C28H24Cl2FN5O2Pureza:97.01% - 98.38%Cor e Forma:SolidPeso molecular:552.43Bredinin aglycone
CAS:<p>Bredinin aglycone (SM-108) is a purine nucleotide analog.</p>Fórmula:C4H5N3O2Pureza:99.06%Cor e Forma:SolidPeso molecular:127.1Palbociclib monohydrochloride
CAS:<p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>Fórmula:C24H29N7O2·HClPureza:99.73% - >99.99%Cor e Forma:SolidPeso molecular:483.99Nolatrexed
CAS:<p>Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.</p>Fórmula:C14H12N4OSPureza:97.53%Cor e Forma:SolidPeso molecular:284.34Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
<p>Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation</p>Fórmula:C76H121N19O25SPureza:98.96%Cor e Forma:SolidPeso molecular:1732.95Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Fórmula:C35H49N11O9S2·xC2H4O2Pureza:99.7% - 99.87%Cor e Forma:SolidPeso molecular:831.96 (free base)roxifiban
CAS:<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Fórmula:C21H29N5O6Pureza:98%Cor e Forma:SolidPeso molecular:447.48PTC-209 hydrobromide
CAS:<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Fórmula:C17H13Br2N5OS·HBrPureza:99.91%Cor e Forma:SolidPeso molecular:576.1CVT-313
CAS:<p>CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.</p>Fórmula:C20H28N6O3Pureza:97.46% - 97.97%Cor e Forma:SolidPeso molecular:400.47YKL-5-124
CAS:<p>YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays</p>Fórmula:C28H33N7O3Pureza:99.36%Cor e Forma:SolidPeso molecular:515.61GW779439X
CAS:<p>GW779439X is an inhibitor of CDK.</p>Fórmula:C22H21F3N8Pureza:97.87%Cor e Forma:SolidPeso molecular:454.45KB-0742 dihydrochloride
CAS:<p>KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.</p>Fórmula:C16H27Cl2N5Pureza:99.79%Cor e Forma:SolidPeso molecular:360.33Besifloxacin Hydrochloride
CAS:<p>Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.</p>Fórmula:C19H21ClFN3O3·HClPureza:99.20%Cor e Forma:Pale Yellow SolidPeso molecular:430.3TH588
CAS:<p>TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.</p>Fórmula:C13H12Cl2N4Pureza:96.05% - 99.82%Cor e Forma:SolidPeso molecular:295.17LP-935509
CAS:<p>LP-935509 is a selective, brain-permeable, small molecule competitive inhibitor of articulin-2-associated kinase 1 (AAK1).Cost-effective and quality-assured.</p>Fórmula:C20H24N6O3Pureza:98.78% - 99.64%Cor e Forma:SolidPeso molecular:396.44Raltitrexed
CAS:<p>Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.</p>Fórmula:C21H22N4O6SPureza:98.99% - 99.29%Cor e Forma:Yellow Crystalline PowderPeso molecular:458.49AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Fórmula:C28H21N7OSPureza:98.4% - 99.51%Cor e Forma:SolidPeso molecular:503.58MKC3946
CAS:<p>MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.</p>Fórmula:C21H20N2O3SPureza:99.65%Cor e Forma:SolidPeso molecular:380.462′-O-Methylcytidine
CAS:<p>2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.</p>Fórmula:C10H15N3O5Pureza:99.72%Cor e Forma:SolidPeso molecular:257.24Palbociclib Isethionate
CAS:<p>Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂,IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。</p>Fórmula:C24H29N7O2·C2H6O4SPureza:99.01% - 99.27%Cor e Forma:SolidPeso molecular:573.66Arginine-glycine-aspartic acid
CAS:<p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>Fórmula:C12H22N6O6Pureza:99.11%Cor e Forma:SolidPeso molecular:346.34Natalizumab
CAS:<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Pureza:98.00%Cor e Forma:LiquidPeso molecular:N/AFUBP1-IN-1
CAS:<p>FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.</p>Fórmula:C19H14F3N3O2SPureza:99.7%Cor e Forma:SolidPeso molecular:405.39BMS-265246
CAS:<p>BMS-265246 is a potent and selective CDK1/2 inhibitor.</p>Fórmula:C18H17F2N3O2Pureza:99.25% - 99.57%Cor e Forma:SolidPeso molecular:345.34ML264
CAS:<p>ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.</p>Fórmula:C17H21ClN2O4SPureza:99.33% - 99.45%Cor e Forma:SolidPeso molecular:384.88XMD8-92
CAS:<p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>Fórmula:C26H30N6O3Pureza:98.21%Cor e Forma:SolidPeso molecular:474.55Verosudil hydrochloride
CAS:<p>Verosudil (AR-12286) is a selective Rho kinase inhibitor, reducing IOP in XFS & OHT/XFG, offering a new treatment option.</p>Fórmula:C17H18ClN3O2SCor e Forma:SolidPeso molecular:363.86CCT241736
CAS:<p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>Fórmula:C22H23Cl2N7Pureza:96.2% - 99.81%Cor e Forma:SolidPeso molecular:456.37NY2267
CAS:<p>NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl</p>Fórmula:C38H43N3O6Pureza:99.16% - 99.27%Cor e Forma:SolidPeso molecular:637.7610058-F4
CAS:<p>10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.</p>Fórmula:C12H11NOS2Pureza:98% - 99.87%Cor e Forma:SolidPeso molecular:249.35BTB-1
CAS:<p>BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.</p>Fórmula:C12H8ClNO4SPureza:99.71%Cor e Forma:SolidPeso molecular:297.71Alisertib
CAS:<p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.</p>Fórmula:C27H20ClFN4O4Pureza:98.31% - >99.99%Cor e Forma:SolidPeso molecular:518.92SNS-314
CAS:<p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>Fórmula:C18H15ClN6OS2Pureza:98%Cor e Forma:SolidPeso molecular:430.93LDN-192960 hydrochloride
CAS:<p>LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.</p>Fórmula:C18H22Cl2N2O2SPureza:98%Cor e Forma:SolidPeso molecular:401.35Abemaciclib
CAS:<p>Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.</p>Fórmula:C27H32F2N8Pureza:99.43% - 99.87%Cor e Forma:SolidPeso molecular:506.59Silver sulfadiazine
CAS:<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Fórmula:C10H9AgN4O2SPureza:99.04% - 99.58%Cor e Forma:SolidPeso molecular:357.14Camostat mesylate
CAS:<p>Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.</p>Fórmula:C21H26N4O8SPureza:99.31% - 99.85%Cor e Forma:Crystalline SolidPeso molecular:494.52Tipiracil
CAS:<p>Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.</p>Fórmula:C9H11ClN4O2Pureza:99.815%Cor e Forma:SolidPeso molecular:242.66H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Fórmula:C23H38N10O10Pureza:>99.99%Cor e Forma:SolidPeso molecular:614.61Adefovir dipivoxil
CAS:<p>Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against</p>Fórmula:C20H32N5O8PPureza:98% - 99.80%Cor e Forma:It Has Broad-Spectrum Antiviral ActivityPeso molecular:501.47Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Fórmula:C25H21FN6O2SPureza:96.17% - 97.49%Cor e Forma:SolidPeso molecular:488.545-Fluorocytidine
CAS:<p>5-Fluorocytidine with antiviral activity</p>Fórmula:C9H12FN3O5Pureza:99.23%Cor e Forma:White PowderPeso molecular:261.21JNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Fórmula:C15H12F2N6O3SPureza:99.1% - 99.85%Cor e Forma:SolidPeso molecular:394.36KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Fórmula:C20H20N4OPureza:98.43% - 99.69%Cor e Forma:SolidPeso molecular:332.46-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS:<p>6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).</p>Fórmula:C8H7BrO3Pureza:99.82%Cor e Forma:SolidPeso molecular:231.04Ara-G
CAS:<p>Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.</p>Fórmula:C10H13N5O5Pureza:98.74%Cor e Forma:Slightly Off White To White PowderPeso molecular:283.24Empesertib
CAS:<p>Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.</p>Fórmula:C29H26FN5O4SPureza:97.45% - 99.4%Cor e Forma:SolidPeso molecular:559.61Longdaysin
CAS:<p>Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).</p>Fórmula:C16H16F3N5Pureza:99.97%Cor e Forma:SolidPeso molecular:335.33Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Fórmula:C26H30N6O3Pureza:97.88% - 98.79%Cor e Forma:White PowderPeso molecular:474.55CCG-100602
CAS:<p>CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).</p>Fórmula:C21H17ClF6N2O2Pureza:99.58%Cor e Forma:SolidPeso molecular:478.824μ8C
CAS:<p>4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.</p>Fórmula:C11H8O4Pureza:97.48% - 98.45%Cor e Forma:SolidPeso molecular:204.18Didox
CAS:<p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>Fórmula:C7H7NO4Pureza:99.83%Cor e Forma:SolidPeso molecular:169.13T56-LIMKi
CAS:<p>T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.</p>Fórmula:C19H14F3N3O3Pureza:98.39% - 99.57%Cor e Forma:SolidPeso molecular:389.33BAY-1816032
CAS:<p>BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor.Cost-effective and quality-assured.</p>Fórmula:C27H24F2N6O4Pureza:98.02% - 99.81%Cor e Forma:SolidPeso molecular:534.51Mycro 3
CAS:<p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>Fórmula:C24H17ClF2N6O4Pureza:99.51% - 99.61%Cor e Forma:SolidPeso molecular:526.88ZCL278
CAS:<p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>Fórmula:C21H19BrClN5O4S2Pureza:96.29% - 99.72%Cor e Forma:SolidPeso molecular:584.89BRD32048
CAS:<p>BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.</p>Fórmula:C16H22N6OPureza:99.87%Cor e Forma:SolidPeso molecular:314.39Tirapazamine
CAS:<p>Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.</p>Fórmula:C7H6N4O2Pureza:96.65% - 99.87%Cor e Forma:Orange-Red Crystalline PowderPeso molecular:178.15GAK inhibitor 49 hydrochloride
<p>Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.</p>Fórmula:C20H23ClN2O5Cor e Forma:SolidPeso molecular:406.86PfDHODH-IN-1
CAS:<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Fórmula:C14H11F3N2O2Pureza:99.87%Cor e Forma:SolidPeso molecular:296.24TP-353
CAS:<p>TP-353 (EOS-61973) is a CDK7 inhibitor.</p>Fórmula:C35H30FNO3Pureza:99.12%Cor e Forma:SolidPeso molecular:531.62ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Fórmula:C21H25N7Pureza:97.63% - ≥95%Cor e Forma:SolidPeso molecular:375.47Isoindigotin
CAS:<p>Isoindigotin is used in the therapy of Y.</p>Fórmula:C16H10N2O2Pureza:98.14% - ≥95%Cor e Forma:SolidPeso molecular:262.26Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Fórmula:C31H43F6N9O12Pureza:95.28% - ≥95%Cor e Forma:SolidPeso molecular:847.72IXA4
CAS:<p>IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.</p>Fórmula:C24H28N4O4Pureza:99.8% - 99.85%Cor e Forma:SolidPeso molecular:436.5Alovudine
CAS:<p>3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.</p>Fórmula:C10H13FN2O4Pureza:99.41%Cor e Forma:Less Solid Colourless SolidPeso molecular:244.22STF-083010
CAS:<p>STF-083010 is a selective inhibitor of the IRE1α endonuclease.</p>Fórmula:C15H11NO3S2Pureza:98.09% - 99.45%Cor e Forma:SolidPeso molecular:317.381,4-Anthraquinone
CAS:<p>1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.</p>Fórmula:C14H8O2Pureza:95.96% - 97.01%Cor e Forma:Orange Brown SolidPeso molecular:208.21BI-1347
CAS:<p>BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.</p>Fórmula:C22H20N4OPureza:96.7% - 99.63%Cor e Forma:SolidPeso molecular:356.42COH29
CAS:<p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>Fórmula:C22H16N2O5SPureza:97.04% - 98.92%Cor e Forma:SolidPeso molecular:420.44Pyridostatin Trihydrochloride
CAS:<p>Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.</p>Fórmula:C31H35Cl3N8O5Pureza:99.69%Cor e Forma:SolidPeso molecular:706.02Fialuridine
CAS:<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Fórmula:C9H10FIN2O5Pureza:99.71% - 99.88%Cor e Forma:Less Crystals Colourless CrystalsPeso molecular:372.09Simeprevir sodium
CAS:<p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>Fórmula:C38H46N5NaO7S2Pureza:98%Cor e Forma:SolidPeso molecular:771.92Dasabuvir
CAS:<p>Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.</p>Fórmula:C26H27N3O5SPureza:99.54% - 99.62%Cor e Forma:SolidPeso molecular:493.57EG1
CAS:<p>EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.</p>Fórmula:C22H18N2O5Pureza:97.48%Cor e Forma:SolidPeso molecular:390.39

