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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

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Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

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  • Abemaciclib methanesulfonate

    CAS:
    <p>Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).</p>
    Fórmula:C27H32F2N8·CH4O3S
    Pureza:98.69% - 99.44%
    Cor e Forma:Solid
    Peso molecular:602.7
  • BUR1

    CAS:
    <p>BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.</p>
    Fórmula:C16H17N5
    Pureza:90%
    Cor e Forma:Solid
    Peso molecular:279.34
  • NSC23005 Sodium

    CAS:
    <p>NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.</p>
    Fórmula:C13H16NNaO4S
    Pureza:99.64%
    Cor e Forma:Solid
    Peso molecular:305.32
  • Monastrol

    CAS:
    <p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>
    Fórmula:C14H16N2O3S
    Pureza:98.02% - 98.59%
    Cor e Forma:Solid
    Peso molecular:292.35
  • AUZ 454

    CAS:
    <p>AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.</p>
    Fórmula:C24H26F3N7O2
    Pureza:99.59%
    Cor e Forma:Solid
    Peso molecular:501.5
  • CX-5461

    CAS:
    <p>CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.</p>
    Fórmula:C27H27N7O2S
    Pureza:95.44% - 99.25%
    Cor e Forma:Solid
    Peso molecular:513.61
  • Pipobroman

    CAS:
    <p>Pipobroman (Vercyte) is an alkylating anti-cancer drug effective in PV and ET with low toxicity and thrombosis risk.</p>
    Fórmula:C10H16Br2N2O2
    Pureza:97.08%
    Cor e Forma:Solid
    Peso molecular:356.05
  • BVDV-IN-1

    CAS:
    <p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>
    Fórmula:C20H22N4O
    Pureza:98.43%
    Cor e Forma:Solid
    Peso molecular:334.41
  • PND-1186

    CAS:
    <p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>
    Fórmula:C25H26F3N5O3
    Pureza:99.14% - 99.75%
    Cor e Forma:Solid
    Peso molecular:501.5
  • 2-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi

    CAS:
    <p>2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate.</p>
    Fórmula:C6H6N4O
    Pureza:99.21% - 99.42%
    Cor e Forma:Solid
    Peso molecular:150.14
  • Myoseverin

    CAS:
    <p>Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.</p>
    Fórmula:C24H28N6O2
    Pureza:99.25%
    Cor e Forma:Solid
    Peso molecular:432.52
  • OSU-T315

    CAS:
    <p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>
    Fórmula:C30H30F3N5O
    Pureza:98.69%
    Cor e Forma:Solid
    Peso molecular:533.59
  • HMN-176

    CAS:
    <p>HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).</p>
    Fórmula:C20H18N2O4S
    Pureza:98.92% - 98.99%
    Cor e Forma:Solid
    Peso molecular:382.43
  • PTC-209

    CAS:
    <p>PTC-209 is a potent and selective BMI-1 inhibitor.</p>
    Fórmula:C17H13Br2N5OS
    Pureza:99.43% - 99.887%
    Cor e Forma:Solid
    Peso molecular:495.19
  • Antitumor agent-152

    CAS:
    <p>Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.</p>
    Fórmula:C17H19N5O2S2
    Pureza:95.00%
    Cor e Forma:Solid
    Peso molecular:389.5
  • TC-E 5003

    CAS:
    <p>TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.</p>
    Fórmula:C16H14Cl2N2O4S
    Pureza:97.01%
    Cor e Forma:Solid
    Peso molecular:401.26
  • PHA-680632

    CAS:
    <p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>
    Fórmula:C28H35N7O2
    Pureza:98.2%
    Cor e Forma:Solid
    Peso molecular:501.62
  • MK-8745

    CAS:
    <p>MK-8745 is a potent and selective Aurora A inhibitor.</p>
    Fórmula:C20H19ClFN5OS
    Pureza:99.09% - 99.79%
    Cor e Forma:Solid
    Peso molecular:431.91
  • Purvalanol B

    CAS:
    <p>Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)</p>
    Fórmula:C20H25ClN6O3
    Pureza:98.95%
    Cor e Forma:Solid
    Peso molecular:432.9
  • C/EBPα inducer 1

    CAS:
    <p>C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via</p>
    Fórmula:C20H12FN3O4
    Pureza:98.99%
    Cor e Forma:Solid
    Peso molecular:377.33
  • VPC-80051 racemate

    CAS:
    <p>VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.</p>
    Fórmula:C16H13F2N3O
    Pureza:97.36%
    Cor e Forma:Solid
    Peso molecular:301.29
  • HALOFUGINONE LACTATE

    CAS:
    <p>HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.</p>
    Fórmula:C19H23BrClN3O6
    Pureza:99.70% - 99.96%
    Cor e Forma:Solid
    Peso molecular:504.8
  • WEE1-IN-3

    CAS:
    <p>WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of &lt;10 nM. It treatment of cancer and other proliferative diseases.</p>
    Fórmula:C28H31N7O2
    Pureza:98.33%
    Cor e Forma:Solid
    Peso molecular:497.59
  • CB-6644

    CAS:
    <p>CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.</p>
    Fórmula:C29H34ClFN4O5
    Pureza:96.33% - 99.85%
    Cor e Forma:Solid
    Peso molecular:573.06
  • 2-Chloropyrazine

    CAS:
    <p>2-Chloropyrazine is used in chemical industry.</p>
    Fórmula:C4H3ClN2
    Pureza:98.98% - 99.89%
    Cor e Forma:Clear Colorless To Yellowish Liquid
    Peso molecular:114.53
  • ARQ 621

    CAS:
    <p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>
    Fórmula:C28H24Cl2FN5O2
    Pureza:97.01% - 98.38%
    Cor e Forma:Solid
    Peso molecular:552.43
  • Bredinin aglycone

    CAS:
    <p>Bredinin aglycone (SM-108) is a purine nucleotide analog.</p>
    Fórmula:C4H5N3O2
    Pureza:99.06%
    Cor e Forma:Solid
    Peso molecular:127.1
  • Palbociclib monohydrochloride

    CAS:
    <p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>
    Fórmula:C24H29N7O2·HCl
    Pureza:99.73% - >99.99%
    Cor e Forma:Solid
    Peso molecular:483.99
  • Nolatrexed

    CAS:
    <p>Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.</p>
    Fórmula:C14H12N4OS
    Pureza:97.53%
    Cor e Forma:Solid
    Peso molecular:284.34
  • Rac1 Inhibitor W56 acetate(1095179-01-3 free base)


    <p>Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation</p>
    Fórmula:C76H121N19O25S
    Pureza:98.96%
    Cor e Forma:Solid
    Peso molecular:1732.95
  • Eptifibatide acetate (148031-34-9 free base)

    CAS:
    <p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>
    Fórmula:C35H49N11O9S2·xC2H4O2
    Pureza:99.7% - 99.87%
    Cor e Forma:Solid
    Peso molecular:831.96 (free base)
  • roxifiban

    CAS:
    <p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>
    Fórmula:C21H29N5O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:447.48
  • PTC-209 hydrobromide

    CAS:
    <p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>
    Fórmula:C17H13Br2N5OS·HBr
    Pureza:99.91%
    Cor e Forma:Solid
    Peso molecular:576.1
  • CVT-313

    CAS:
    <p>CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.</p>
    Fórmula:C20H28N6O3
    Pureza:97.46% - 97.97%
    Cor e Forma:Solid
    Peso molecular:400.47
  • YKL-5-124

    CAS:
    <p>YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays</p>
    Fórmula:C28H33N7O3
    Pureza:99.36%
    Cor e Forma:Solid
    Peso molecular:515.61
  • GW779439X

    CAS:
    <p>GW779439X is an inhibitor of CDK.</p>
    Fórmula:C22H21F3N8
    Pureza:97.87%
    Cor e Forma:Solid
    Peso molecular:454.45
  • KB-0742 dihydrochloride

    CAS:
    <p>KB-0742 dihydrochloride is a potent, selective and orally inhibitor of  CDK9.</p>
    Fórmula:C16H27Cl2N5
    Pureza:99.79%
    Cor e Forma:Solid
    Peso molecular:360.33
  • Besifloxacin Hydrochloride

    CAS:
    <p>Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.</p>
    Fórmula:C19H21ClFN3O3·HCl
    Pureza:99.20%
    Cor e Forma:Pale Yellow Solid
    Peso molecular:430.3
  • TH588

    CAS:
    <p>TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.</p>
    Fórmula:C13H12Cl2N4
    Pureza:96.05% - 99.82%
    Cor e Forma:Solid
    Peso molecular:295.17
  • LP-935509

    CAS:
    <p>LP-935509 is a selective, brain-permeable, small molecule competitive inhibitor of articulin-2-associated kinase 1 (AAK1).Cost-effective and quality-assured.</p>
    Fórmula:C20H24N6O3
    Pureza:98.78% - 99.64%
    Cor e Forma:Solid
    Peso molecular:396.44
  • Raltitrexed

    CAS:
    <p>Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.</p>
    Fórmula:C21H22N4O6S
    Pureza:98.99% - 99.29%
    Cor e Forma:Yellow Crystalline Powder
    Peso molecular:458.49
  • AMG 900

    CAS:
    <p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>
    Fórmula:C28H21N7OS
    Pureza:98.4% - 99.51%
    Cor e Forma:Solid
    Peso molecular:503.58
  • MKC3946

    CAS:
    <p>MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.</p>
    Fórmula:C21H20N2O3S
    Pureza:99.65%
    Cor e Forma:Solid
    Peso molecular:380.46
  • 2′-O-Methylcytidine

    CAS:
    <p>2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.</p>
    Fórmula:C10H15N3O5
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:257.24
  • Palbociclib Isethionate

    CAS:
    <p>Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂,IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。</p>
    Fórmula:C24H29N7O2·C2H6O4S
    Pureza:99.01% - 99.27%
    Cor e Forma:Solid
    Peso molecular:573.66
  • Arginine-glycine-aspartic acid

    CAS:
    <p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>
    Fórmula:C12H22N6O6
    Pureza:99.11%
    Cor e Forma:Solid
    Peso molecular:346.34
  • Natalizumab

    CAS:
    <p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>
    Pureza:98.00%
    Cor e Forma:Liquid
    Peso molecular:N/A
  • FUBP1-IN-1

    CAS:
    <p>FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.</p>
    Fórmula:C19H14F3N3O2S
    Pureza:99.7%
    Cor e Forma:Solid
    Peso molecular:405.39
  • BMS-265246

    CAS:
    <p>BMS-265246 is a potent and selective CDK1/2 inhibitor.</p>
    Fórmula:C18H17F2N3O2
    Pureza:99.25% - 99.57%
    Cor e Forma:Solid
    Peso molecular:345.34
  • ML264

    CAS:
    <p>ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.</p>
    Fórmula:C17H21ClN2O4S
    Pureza:99.33% - 99.45%
    Cor e Forma:Solid
    Peso molecular:384.88
  • XMD8-92

    CAS:
    <p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>
    Fórmula:C26H30N6O3
    Pureza:98.21%
    Cor e Forma:Solid
    Peso molecular:474.55
  • Verosudil hydrochloride

    CAS:
    <p>Verosudil (AR-12286) is a selective Rho kinase inhibitor, reducing IOP in XFS &amp; OHT/XFG, offering a new treatment option.</p>
    Fórmula:C17H18ClN3O2S
    Cor e Forma:Solid
    Peso molecular:363.86
  • CCT241736

    CAS:
    <p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>
    Fórmula:C22H23Cl2N7
    Pureza:96.2% - 99.81%
    Cor e Forma:Solid
    Peso molecular:456.37
  • NY2267

    CAS:
    <p>NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl</p>
    Fórmula:C38H43N3O6
    Pureza:99.16% - 99.27%
    Cor e Forma:Solid
    Peso molecular:637.76
  • 10058-F4

    CAS:
    <p>10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest &amp; apoptosis.</p>
    Fórmula:C12H11NOS2
    Pureza:98% - 99.87%
    Cor e Forma:Solid
    Peso molecular:249.35
  • BTB-1

    CAS:
    <p>BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.</p>
    Fórmula:C12H8ClNO4S
    Pureza:99.71%
    Cor e Forma:Solid
    Peso molecular:297.71
  • Alisertib

    CAS:
    <p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is &gt;200-fold higher for Aurora A than Aurora B.</p>
    Fórmula:C27H20ClFN4O4
    Pureza:98.31% - >99.99%
    Cor e Forma:Solid
    Peso molecular:518.92
  • SNS-314

    CAS:
    <p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>
    Fórmula:C18H15ClN6OS2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:430.93
  • LDN-192960 hydrochloride

    CAS:
    <p>LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.</p>
    Fórmula:C18H22Cl2N2O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:401.35
  • Abemaciclib

    CAS:
    <p>Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.</p>
    Fórmula:C27H32F2N8
    Pureza:99.43% - 99.87%
    Cor e Forma:Solid
    Peso molecular:506.59
  • Silver sulfadiazine

    CAS:
    <p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>
    Fórmula:C10H9AgN4O2S
    Pureza:99.04% - 99.58%
    Cor e Forma:Solid
    Peso molecular:357.14
  • Camostat mesylate

    CAS:
    <p>Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.</p>
    Fórmula:C21H26N4O8S
    Pureza:99.31% - 99.85%
    Cor e Forma:Crystalline Solid
    Peso molecular:494.52
  • Tipiracil

    CAS:
    <p>Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.</p>
    Fórmula:C9H11ClN4O2
    Pureza:99.815%
    Cor e Forma:Solid
    Peso molecular:242.66
  • H-Gly-Arg-Gly-Asp-Asn-Pro-OH

    CAS:
    <p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>
    Fórmula:C23H38N10O10
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:614.61
  • Adefovir dipivoxil

    CAS:
    <p>Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against</p>
    Fórmula:C20H32N5O8P
    Pureza:98% - 99.80%
    Cor e Forma:It Has Broad-Spectrum Antiviral Activity
    Peso molecular:501.47
  • Ilorasertib

    CAS:
    <p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C &amp; RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>
    Fórmula:C25H21FN6O2S
    Pureza:96.17% - 97.49%
    Cor e Forma:Solid
    Peso molecular:488.54
  • 5-Fluorocytidine

    CAS:
    <p>5-Fluorocytidine with antiviral activity</p>
    Fórmula:C9H12FN3O5
    Pureza:99.23%
    Cor e Forma:White Powder
    Peso molecular:261.21
  • JNJ-7706621

    CAS:
    <p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>
    Fórmula:C15H12F2N6O3S
    Pureza:99.1% - 99.85%
    Cor e Forma:Solid
    Peso molecular:394.36
  • KW-2449

    CAS:
    <p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>
    Fórmula:C20H20N4O
    Pureza:98.43% - 99.69%
    Cor e Forma:Solid
    Peso molecular:332.4
  • 6-Bromo-2-hydroxy-3-methoxybenzaldehyde

    CAS:
    <p>6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).</p>
    Fórmula:C8H7BrO3
    Pureza:99.82%
    Cor e Forma:Solid
    Peso molecular:231.04
  • Ara-G

    CAS:
    <p>Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.</p>
    Fórmula:C10H13N5O5
    Pureza:98.74%
    Cor e Forma:Slightly Off White To White Powder
    Peso molecular:283.24
  • Empesertib

    CAS:
    <p>Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 &lt; 1 nM), with potential antineoplastic activity.</p>
    Fórmula:C29H26FN5O4S
    Pureza:97.45% - 99.4%
    Cor e Forma:Solid
    Peso molecular:559.61
  • Longdaysin

    CAS:
    <p>Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).</p>
    Fórmula:C16H16F3N5
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:335.33
  • Danusertib

    CAS:
    <p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>
    Fórmula:C26H30N6O3
    Pureza:97.88% - 98.79%
    Cor e Forma:White Powder
    Peso molecular:474.55
  • CCG-100602

    CAS:
    <p>CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).</p>
    Fórmula:C21H17ClF6N2O2
    Pureza:99.58%
    Cor e Forma:Solid
    Peso molecular:478.82
  • 4μ8C

    CAS:
    <p>4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.</p>
    Fórmula:C11H8O4
    Pureza:97.48% - 98.45%
    Cor e Forma:Solid
    Peso molecular:204.18
  • Didox

    CAS:
    <p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>
    Fórmula:C7H7NO4
    Pureza:99.83%
    Cor e Forma:Solid
    Peso molecular:169.13
  • T56-LIMKi

    CAS:
    <p>T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.</p>
    Fórmula:C19H14F3N3O3
    Pureza:98.39% - 99.57%
    Cor e Forma:Solid
    Peso molecular:389.33
  • BAY-1816032

    CAS:
    <p>BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor.Cost-effective and quality-assured.</p>
    Fórmula:C27H24F2N6O4
    Pureza:98.02% - 99.81%
    Cor e Forma:Solid
    Peso molecular:534.51
  • Mycro 3

    CAS:
    <p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>
    Fórmula:C24H17ClF2N6O4
    Pureza:99.51% - 99.61%
    Cor e Forma:Solid
    Peso molecular:526.88
  • ZCL278

    CAS:
    <p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>
    Fórmula:C21H19BrClN5O4S2
    Pureza:96.29% - 99.72%
    Cor e Forma:Solid
    Peso molecular:584.89
  • BRD32048

    CAS:
    <p>BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.</p>
    Fórmula:C16H22N6O
    Pureza:99.87%
    Cor e Forma:Solid
    Peso molecular:314.39
  • Tirapazamine

    CAS:
    <p>Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.</p>
    Fórmula:C7H6N4O2
    Pureza:96.65% - 99.87%
    Cor e Forma:Orange-Red Crystalline Powder
    Peso molecular:178.15
  • GAK inhibitor 49 hydrochloride


    <p>Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.</p>
    Fórmula:C20H23ClN2O5
    Cor e Forma:Solid
    Peso molecular:406.86
  • PfDHODH-IN-1

    CAS:
    <p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>
    Fórmula:C14H11F3N2O2
    Pureza:99.87%
    Cor e Forma:Solid
    Peso molecular:296.24
  • TP-353

    CAS:
    <p>TP-353 (EOS-61973) is a CDK7 inhibitor.</p>
    Fórmula:C35H30FNO3
    Pureza:99.12%
    Cor e Forma:Solid
    Peso molecular:531.62
  • ENMD-2076

    CAS:
    <p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>
    Fórmula:C21H25N7
    Pureza:97.63% - ≥95%
    Cor e Forma:Solid
    Peso molecular:375.47
  • Isoindigotin

    CAS:
    <p>Isoindigotin is used in the therapy of Y.</p>
    Fórmula:C16H10N2O2
    Pureza:98.14% - ≥95%
    Cor e Forma:Solid
    Peso molecular:262.26
  • Cyclo(RGDyK) trifluoroacetate

    CAS:
    <p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>
    Fórmula:C31H43F6N9O12
    Pureza:95.28% - ≥95%
    Cor e Forma:Solid
    Peso molecular:847.72
  • IXA4

    CAS:
    <p>IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.</p>
    Fórmula:C24H28N4O4
    Pureza:99.8% - 99.85%
    Cor e Forma:Solid
    Peso molecular:436.5
  • Alovudine

    CAS:
    <p>3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.</p>
    Fórmula:C10H13FN2O4
    Pureza:99.41%
    Cor e Forma:Less Solid Colourless Solid
    Peso molecular:244.22
  • STF-083010

    CAS:
    <p>STF-083010 is a selective inhibitor of the IRE1α endonuclease.</p>
    Fórmula:C15H11NO3S2
    Pureza:98.09% - 99.45%
    Cor e Forma:Solid
    Peso molecular:317.38
  • 1,4-Anthraquinone

    CAS:
    <p>1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.</p>
    Fórmula:C14H8O2
    Pureza:95.96% - 97.01%
    Cor e Forma:Orange Brown Solid
    Peso molecular:208.21
  • BI-1347

    CAS:
    <p>BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.</p>
    Fórmula:C22H20N4O
    Pureza:96.7% - 99.63%
    Cor e Forma:Solid
    Peso molecular:356.42
  • COH29

    CAS:
    <p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>
    Fórmula:C22H16N2O5S
    Pureza:97.04% - 98.92%
    Cor e Forma:Solid
    Peso molecular:420.44
  • Pyridostatin Trihydrochloride

    CAS:
    <p>Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.</p>
    Fórmula:C31H35Cl3N8O5
    Pureza:99.69%
    Cor e Forma:Solid
    Peso molecular:706.02
  • Fialuridine

    CAS:
    <p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>
    Fórmula:C9H10FIN2O5
    Pureza:99.71% - 99.88%
    Cor e Forma:Less Crystals Colourless Crystals
    Peso molecular:372.09
  • Simeprevir sodium

    CAS:
    <p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>
    Fórmula:C38H46N5NaO7S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:771.92
  • Dasabuvir

    CAS:
    <p>Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.</p>
    Fórmula:C26H27N3O5S
    Pureza:99.54% - 99.62%
    Cor e Forma:Solid
    Peso molecular:493.57
  • EG1

    CAS:
    <p>EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.</p>
    Fórmula:C22H18N2O5
    Pureza:97.48%
    Cor e Forma:Solid
    Peso molecular:390.39