Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(94 produtos)
- CDK(500 produtos)
- Ciclo celular/Parada(4 produtos)
- Chk(42 produtos)
- DYRK(48 produtos)
- Dinamina(23 produtos)
- Ferroptose(215 produtos)
- HSP(169 produtos)
- Integrinas(224 produtos)
- Cinesina(66 produtos)
- LIM Quinase(19 produtos)
- Microtúbulo associado(261 produtos)
- PKC(102 produtos)
- PLK(28 produtos)
- ROCK(70 produtos)
- Rho(2 produtos)
- Wee1(15 produtos)
- c-Myc(69 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
SB-743921 hydrochloride
CAS:<p>SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).</p>Fórmula:C31H34Cl2N2O3Pureza:95.58% - 99.70%Cor e Forma:SolidPeso molecular:553.525-Chloro-2'-deoxyuridine
CAS:<p>5-Chloro-2'-deoxyuridine (5-Chlorodeoxyuridine) is a thymine analog.</p>Fórmula:C9H11ClN2O5Pureza:99.54%Cor e Forma:SolidPeso molecular:262.65SRI-29329
CAS:<p>SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).</p>Fórmula:C20H26ClN7Pureza:99.18%Cor e Forma:SolidPeso molecular:399.92Reversine
CAS:<p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>Fórmula:C21H27N7OPureza:98% - 98.42%Cor e Forma:SolidPeso molecular:393.49NSC23005
CAS:<p>NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).</p>Fórmula:C13H17NO4SPureza:>99.99%Cor e Forma:SolidPeso molecular:283.34CDK9-IN-30
CAS:<p>CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.</p>Fórmula:C16H20FNO3Pureza:99.75%Cor e Forma:SolidPeso molecular:293.33Lifitegrast
CAS:<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Fórmula:C29H24Cl2N2O7SPureza:99.39% - 99.66%Cor e Forma:SolidPeso molecular:615.48TH287 hydrochloride
CAS:<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Fórmula:C11H11Cl3N4Pureza:>99.99%Cor e Forma:SolidPeso molecular:305.59ILK-IN-3
CAS:<p>ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.</p>Fórmula:C10H12N6OPureza:99.69%Cor e Forma:SolidPeso molecular:232.24Peldesine dihydrochloride
CAS:<p>Peldesine (BCX 34) dihydrochloride is an inhibitor of PNP in humans, rats, and mice, also hindering T-cell proliferation, used in lymphoma and HIV research.</p>Fórmula:C12H13Cl2N5OCor e Forma:SolidPeso molecular:314.17THZ1 Hydrochloride
<p>THZ1 Hydrochloride: selective covalent CDK7 inhibitor, IC50 of 3.2 nM; affects CDK12/13 & lowers MYC expression.</p>Fórmula:C31H29Cl2N7O2Cor e Forma:SolidPeso molecular:602.51Temozolomide Acid
CAS:<p>TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.</p>Fórmula:C6H5N5O3Pureza:99.28%Cor e Forma:SolidPeso molecular:195.14ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Fórmula:C29H31N5O4Pureza:99.11% - 99.59%Cor e Forma:Pale Yellow SolidPeso molecular:513.596-Chloropurine riboside
CAS:<p>6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.</p>Fórmula:C10H11ClN4O4Pureza:96.84%Cor e Forma:SoildPeso molecular:286.6700Chroman 1 dihydrochloride
<p>Chroman 1 dihydrochloride: potent ROCK2 inhibitor (IC50: 1 pM), also affects ROCK1 (52 pM) and MRCK (150 nM).</p>Fórmula:C24H30Cl2N4O4Cor e Forma:SolidPeso molecular:509.43Cyclo(RADfK)
CAS:<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Fórmula:C28H43N9O7Pureza:>99.99%Cor e Forma:SolidPeso molecular:617.72'-Deoxy-N2-methylguanosine
CAS:<p>2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.</p>Fórmula:C11H15N5O4Pureza:99.79%Cor e Forma:SolidPeso molecular:281.27BC-1471
CAS:<p>BC-1471 is a STAMBP deubiquitinase inhibitor that blocks NALP7 inflammasome activity.</p>Fórmula:C27H32N4O4SPureza:99.98%Cor e Forma:SolidPeso molecular:508.635-Hydroxyuridine
CAS:<p>5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.</p>Fórmula:C9H12N2O7Pureza:98.76%Cor e Forma:SolidPeso molecular:260.22'-Deoxy-N4-methylcytidine
CAS:<p>2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.</p>Fórmula:C10H15N3O4Pureza:99.61%Cor e Forma:SolidPeso molecular:241.24Muromonab
CAS:<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Pureza:95% - 97.51% (SEC-HPLC)Cor e Forma:LiquidEtaracizumab
CAS:<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Pureza:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.3 (kDa)O6-Methyldeoxy guanosine
CAS:<p>O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.</p>Fórmula:C11H15N5O4Pureza:99.57%Cor e Forma:SolidPeso molecular:281.27Rabacfosadine
CAS:<p>Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.</p>Fórmula:C21H35N8O6PPureza:99.06% - 99.37%Cor e Forma:SolidPeso molecular:526.53N6-Methyl-2'-O-methyladenosine
CAS:<p>N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found</p>Fórmula:C12H17N5O4Pureza:99.97%Cor e Forma:SolidPeso molecular:295.29N6-(p-Methoxybenzyl)adenosine
CAS:<p>Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormone</p>Fórmula:C18H21N5O5Pureza:99.79%Cor e Forma:SolidPeso molecular:387.39DS44960156
CAS:<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Fórmula:C20H15NO5Pureza:99.13%Cor e Forma:SolidPeso molecular:349.349-(β-D-Xylofuranosyl)adenine
CAS:<p>9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has</p>Fórmula:C10H13N5O4Pureza:99.97%Cor e Forma:SolidPeso molecular:267.242'-O-(2-Methoxyethyl)adenosine
CAS:<p>2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.</p>Fórmula:C13H19N5O5Pureza:99.35%Cor e Forma:SolidPeso molecular:325.32P-2'-deoxyribose
CAS:<p>P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.</p>Fórmula:C11H15N3O5Pureza:99.71%Cor e Forma:SolidPeso molecular:269.25PolQi2
CAS:<p>PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.</p>Fórmula:C21H16ClN5O3SPureza:99.19%Cor e Forma:SolidPeso molecular:453.9LSN2839567
CAS:<p>LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.</p>Fórmula:C25H28F2N8Pureza:99.14%Cor e Forma:SolidPeso molecular:478.542'-C-β-Methylguanosine
CAS:<p>2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.</p>Fórmula:C11H15N5O5Pureza:99.37%Cor e Forma:SolidPeso molecular:297.275'-O-DMT-N4-Bz-5-Me-dC
CAS:<p>5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.</p>Fórmula:C38H37N3O7Pureza:98.88%Cor e Forma:SolidPeso molecular:647.725-Bromouridine
CAS:<p>5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.</p>Fórmula:C9H11BrN2O6Pureza:99.89%Cor e Forma:White PowderPeso molecular:323.1CDK12-IN-5
CAS:<p>CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.</p>Fórmula:C18H15F5N8OPureza:99.37%Cor e Forma:SolidPeso molecular:454.36Braco-19
CAS:<p>Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.</p>Fórmula:C35H43N7O2Pureza:97.01%Cor e Forma:SolidPeso molecular:593.763'-Deoxy-3'-fluoroadenosine
CAS:<p>3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne</p>Fórmula:C10H12FN5O3Pureza:99.84%Cor e Forma:SolidPeso molecular:269.23ARB-272572
CAS:<p>ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.</p>Fórmula:C32H36N6O4Pureza:97.36% - 98.07%Cor e Forma:SolidPeso molecular:568.675-Bromo-2',3',5'-tri-O-acetyluridine
CAS:<p>5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.</p>Fórmula:C15H17BrN2O9Pureza:99%Cor e Forma:SolidPeso molecular:449.212'-O-Methyl-2-thiouridine
CAS:<p>2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.</p>Fórmula:C10H14N2O5SPureza:99.89%Cor e Forma:SolidPeso molecular:274.292'-Deoxy-2-iodoadenosine
CAS:<p>2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.</p>Fórmula:C10H12IN5O3Pureza:99.37%Cor e Forma:SolidPeso molecular:377.14RO0270608
CAS:<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Fórmula:C24H19Cl3N2O4Pureza:98.26%Cor e Forma:SolidPeso molecular:505.78Bexotegrast
CAS:<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Fórmula:C27H36N6O3Pureza:99.53%Cor e Forma:SolidPeso molecular:492.61AZ5576
CAS:<p>AZ5576 is a potent and highly selective CDK9 inhibitor. AZ5576 can be used for the research of Hematological Malignancy [1].</p>Fórmula:C21H24FN3O3Pureza:99.88%Cor e Forma:SoildPeso molecular:385.43Z62954982
CAS:<p>Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteries</p>Fórmula:C20H21N3O5SPureza:98.28%Cor e Forma:SolidPeso molecular:415.46N6-(2-Hydroxyethyl)adenosine
CAS:<p>N6-(2-Hydroxyethyl)adenosine is a sedative, Ca2+ antagonist, and anti-inflammatory, affecting brain and heart blood flow.</p>Fórmula:C12H17N5O5Pureza:99.4%Cor e Forma:SolidPeso molecular:311.29PDD00017273
CAS:<p>PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.</p>Fórmula:C23H26N6O4S2Pureza:99.14% - 99.21%Cor e Forma:SolidPeso molecular:514.622',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS:<p>2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.</p>Fórmula:C21H40N2O6Si2Pureza:99.88%Cor e Forma:SolidPeso molecular:472.72SCH-1473759 hydrochloride
CAS:<p>SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).</p>Fórmula:C20H27ClN8OSPureza:98.29%Cor e Forma:SolidPeso molecular:463MK-5108
CAS:<p>MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.</p>Fórmula:C22H21ClFN3O3SPureza:99.22%Cor e Forma:SolidPeso molecular:461.94Mps1-IN-2
CAS:<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Cor e Forma:SolidPeso molecular:480.65-Methyl-5,6-dihydrouridine
CAS:<p>5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. It can be used for nucleic acid modification.</p>Fórmula:C10H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:260.24Vatelizumab
CAS:<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Pureza:95%Cor e Forma:LiquidLinvoseltamab
CAS:<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Cor e Forma:LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Pureza:98%Cor e Forma:Odour LiquidDHX9-IN-8
CAS:<p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>Fórmula:C18H16N2O3S2Cor e Forma:SolidPeso molecular:372.46Obrindatamab
CAS:<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Cor e Forma:LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Pureza:95%Cor e Forma:Odour LiquidRinatabart
CAS:<p>Rinatabart is a humanised monoclonal antibody targeting FRα/FOLR1, suitable for investigating ovarian and endometrial cancers expressing FRα.</p>Pureza:95% - 95%Cor e Forma:Odour LiquidVVD-214
CAS:<p>VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.</p>Fórmula:C20H21F2N3O4SPureza:99.24%Cor e Forma:SoildPeso molecular:437.46Vepsitamab
CAS:<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Cor e Forma:LiquidRovelizumab
CAS:<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Cor e Forma:LiquidUbamatamab
CAS:<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Cor e Forma:LiquidPacanalotamab
CAS:<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Cor e Forma:LiquidPasotuxizumab
CAS:<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Cor e Forma:LiquidFlotetuzumab
CAS:<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Cor e Forma:LiquidEnlimomab
CAS:<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Cor e Forma:LiquidVoxalatamab
CAS:<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Cor e Forma:LiquidLocked nucleic acid 1
CAS:<p>Locked nucleic acid 1 is an LNA-type nucleoside derivative.</p>Fórmula:C32H32N2O8Pureza:98%Cor e Forma:SolidPeso molecular:572.61Cevostamab
CAS:<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Cor e Forma:LiquidAnti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Pureza:99%Cor e Forma:Odour LiquidMetribuzin
CAS:<p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>Fórmula:C8H14N4OSPureza:99.07%Cor e Forma:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Peso molecular:214.29N6-Etheno 2'-deoxyadenosine
CAS:<p>N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.</p>Fórmula:C12H13N5O3Pureza:98%Cor e Forma:SolidPeso molecular:275.26Vibecotamab
CAS:<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Cor e Forma:LiquidPOSH-IN-1
CAS:<p>POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.</p>Fórmula:C14H8FNO3SPureza:99.29%Cor e Forma:SolidPeso molecular:289.28Tepoditamab
CAS:<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Cor e Forma:LiquidVonsetamig
CAS:<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Cor e Forma:LiquidPavurutamab
CAS:<p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>Cor e Forma:LiquidGresonitamab
CAS:<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Cor e Forma:LiquidGSK4418959
CAS:<p>GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.</p>Fórmula:C31H30F4N4O5SPureza:99.141%Cor e Forma:SoildPeso molecular:646.65D-F07
CAS:<p>D-F07 is a novel fluorescent IRE-1 RNase inhibitor and a tricyclic chromone with potential anticancer activity.</p>Fórmula:C18H21NO6Pureza:98.31% - 99.31%Cor e Forma:SoildPeso molecular:347.36Mirvetuximab soravtansine
CAS:<p>Mirvetuximab soravtansine (IMGN853) is an antibody-drug coupling that targets FRα, inhibits cell growth, and can be used to study drug-resistant ovarian cancer</p>Pureza:6mg/ml - 6mg/mlCor e Forma:LiquidPeso molecular:150000 (average)2'-Azido-2'-deoxyuridine
CAS:<p>2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.</p>Fórmula:C9H11N5O5Pureza:98%Cor e Forma:SolidPeso molecular:269.21L-Threonolactone
CAS:<p>L-Threonolactone is a Carbohydrate Derivative.</p>Fórmula:C4H6O4Cor e Forma:SolidPeso molecular:118.09Adenosine 2'-PEG-Biotin
CAS:<p>Adenosine 2'-PEG-Biotin, a bioreagent derived from adenosine, modulates cellular signaling pathways by mimicking the action of endogenous adenosine and binding to its receptors. This compound is used in research related to bioprobes, biosensors, and diagnostic agents.</p>Fórmula:C26H40N8O8SCor e Forma:SolidPeso molecular:624.71E-982
CAS:<p>E-982 is derived from the reference compound.</p>Fórmula:C25H31NO6SPureza:98%Cor e Forma:SolidPeso molecular:473.58RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Fórmula:C19H17N3Cor e Forma:SolidPeso molecular:287.36hDHODH-IN-2
CAS:<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Fórmula:C19H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:304.349SB273005
CAS:<p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>Fórmula:C22H24F3N3O4Pureza:99.58%Cor e Forma:SolidPeso molecular:451.44(R)-(+)-O-Demethylbuchenavianine
CAS:<p>(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, >10 μM, >10 μM, and >10 μM, respectively.</p>Fórmula:C21H21NO4Cor e Forma:SolidPeso molecular:351.40XL413
CAS:<p>XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.</p>Fórmula:C14H12ClN3O2Pureza:98.40% - >99.99%Cor e Forma:SolidPeso molecular:289.72Mps1-IN-1
CAS:<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Fórmula:C28H33N5O4SPureza:98.33%Cor e Forma:SolidPeso molecular:535.66BAY1217389
CAS:<p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).</p>Fórmula:C27H24F5N5O3Pureza:98.14% - 99.42%Cor e Forma:SolidPeso molecular:561.53,4-Dihydroxybenzylamine hydrobromide
CAS:<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Fórmula:C7H10BrNO2Pureza:98.49%Cor e Forma:Light Beige Crystalline PowderPeso molecular:220.06Tirofiban
CAS:<p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>Fórmula:C22H36N2O5SPureza:99.83%Cor e Forma:SolidPeso molecular:440.6LIMK1 inhibitor BMS-4
CAS:<p>BMS-4 is a LIMK inhibitor targeting LIMK1/2, reduces cofilin phosphorylation, noncytotoxic to A549 cells.</p>Fórmula:C23H23N7O2SCor e Forma:SolidPeso molecular:461.54DENV-IN-7
CAS:<p>DENV-IN-7, a flavone analog, inhibits dengue virus at 70 nM EC50 with low toxicity to normal cells.</p>Fórmula:C24H22O8Cor e Forma:SolidPeso molecular:438.43BSJ-01-175
CAS:<p>BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.</p>Fórmula:C30H33ClN6O2Cor e Forma:SolidPeso molecular:545.08Digeranyl bisphosphonate
CAS:<p>Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl</p>Fórmula:C21H34Na4O6P2Pureza:98.5%Cor e Forma:SolidPeso molecular:536.4
