Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(94 produtos)
- CDK(500 produtos)
- Ciclo celular/Parada(4 produtos)
- Chk(42 produtos)
- DYRK(48 produtos)
- Dinamina(23 produtos)
- Ferroptose(215 produtos)
- HSP(169 produtos)
- Integrinas(224 produtos)
- Cinesina(66 produtos)
- LIM Quinase(19 produtos)
- Microtúbulo associado(261 produtos)
- PKC(102 produtos)
- PLK(28 produtos)
- ROCK(70 produtos)
- Rho(2 produtos)
- Wee1(15 produtos)
- c-Myc(69 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"
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D-Xylofuranose, 1,2,3,5-tetraacetate
CAS:<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>Fórmula:C13H18O9Cor e Forma:SolidPeso molecular:318.28Myt1-IN-1
CAS:<p>Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].</p>Fórmula:C16H15ClN4O2Cor e Forma:SolidPeso molecular:330.77AM-TS23
CAS:<p>AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.</p>Fórmula:C17H12N2O3S3Pureza:98%Cor e Forma:SolidPeso molecular:388.48ML366
CAS:<p>ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.</p>Fórmula:C17H19N3O4Pureza:98%Cor e Forma:SolidPeso molecular:329.35HBX28258
CAS:<p>HBX28258, a human USP7 inhibitor, binds covalently and selectively deactivates USP7 in colon cancer and kidney cells.</p>Fórmula:C26H30ClN3OPureza:98%Cor e Forma:SolidPeso molecular:435.99JNJ-9676
CAS:<p>JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.</p>Fórmula:C28H21F2N5O2Pureza:99.83%Cor e Forma:SoildPeso molecular:497.5DHODH-IN-3
CAS:<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Fórmula:C17H13ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:312.75OXA-06 Dihydrochloride
CAS:<p>OXA-06 Dihydrochloride is a PANC-1 cell migration and MYPT1 phosphorylation inhibitor.</p>Fórmula:C21H18FN3Pureza:98%Cor e Forma:SolidPeso molecular:331.39Lysine-methotrexate
CAS:<p>Lysine-methotrexate is an anticancer drug. It is an inhibitor of dihydrofolate reductase.</p>Fórmula:C21H27N9O3Pureza:98%Cor e Forma:SolidPeso molecular:453.5Type II topoisomerase inhibitor 1
CAS:<p>Potent E. coli DNA gyrase inhibitor (IC50: 1.7 nM), targets Asp73; weak topoisomerase IV inhibitor (IC50: 0.98 μM).</p>Fórmula:C18H15N3O4Cor e Forma:SolidPeso molecular:337.33Ulecaciclib
CAS:<p>Ulecaciclib: oral, BBB-permeable CDK inhibitor; favorable pharmacokinetics; ki: 0.62 μM (CDK2/A), 3 nM (CDK6/D3), 0.2 nM (CDK4/D1), 0.63 μM (CDK7/H).</p>Fórmula:C25H33FN8SCor e Forma:SolidPeso molecular:496.65LY 207702
CAS:<p>LY 207702, a difluorinated purine nucleoside, exhibits antitumor activity in preclinical models.</p>Fórmula:C10H12F2N6O3Pureza:98%Cor e Forma:SolidPeso molecular:302.24Codon readthrough inducer 1
CAS:<p>Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.</p>Fórmula:C15H11N3O5Pureza:98%Cor e Forma:SolidPeso molecular:313.26MS0017509
CAS:<p>MS0017509 is a DNA damage repair inhibitor.</p>Fórmula:C11H10N4Pureza:98%Cor e Forma:SolidPeso molecular:198.22Cdc7-IN-13
CAS:<p>Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].</p>Fórmula:C18H20N4O2SCor e Forma:SolidPeso molecular:356.44AZD7762 HCl
CAS:<p>AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.</p>Fórmula:C17H20ClFN4O2SPureza:98%Cor e Forma:SolidPeso molecular:398.882'-Fluorothymidine
CAS:<p>2'-Fluorothymidine is a selective substrate for TK2, related to thymidine and methyluridine.</p>Fórmula:C10H13FN2O5Pureza:99.67%Cor e Forma:SolidPeso molecular:260.22GR 144053 trihydrochloride
CAS:<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Fórmula:C18H30Cl3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:454.82VPC-70619
CAS:<p>VPC-70619: Oral, selective N-Myc inhibitor; blocks cancer growth by hindering N-Myc-Max/DNA binding; well-absorbed.</p>Fórmula:C16H8ClF3N4OCor e Forma:SolidPeso molecular:364.71Tetrahydrouridine
CAS:<p>Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.</p>Fórmula:C9H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:248.23Cdc7-IN-9
CAS:<p>Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].</p>Fórmula:C15H17N5OSCor e Forma:SolidPeso molecular:315.39CID 5951923
CAS:<p>CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.</p>Fórmula:C16H18N2O7SPureza:99.95%Cor e Forma:SolidPeso molecular:382.39DAP-81
CAS:<p>DAP-81, a diaminopyrimidine, inhibits Plk1 (IC50: 0.9 nM), disrupts microtubules, causes monopolar spindles; in preclinical studies.</p>Fórmula:C25H20N6O4Cor e Forma:SolidPeso molecular:468.46CDK4/6-IN-9
CAS:<p>CDK4/6-IN-9 selectively inhibits CDK4/6 (IC50: 905 nM); potential for MM research.</p>Fórmula:C22H23FN8Cor e Forma:SolidPeso molecular:418.47HBV-IN-16
CAS:<p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>Fórmula:C22H20ClNO4Cor e Forma:SolidPeso molecular:397.85CDK7-IN-12
CAS:<p>CDK7-IN-12 inhibits CDK7 to control transcription and cell cycle, halting tumor growth in vitro/vivo with cancer research potential.</p>Fórmula:C20H19F3N6Cor e Forma:SolidPeso molecular:400.4Phelorphan
CAS:<p>Phelorphan is an inhibitor of enkephalinase.</p>Fórmula:C20H22N2O4SPureza:98%Cor e Forma:SolidPeso molecular:386.46Crisnatol mesylate
CAS:<p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>Fórmula:C24H27NO5SCor e Forma:SolidPeso molecular:441.54BAY-958
CAS:<p>BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.</p>Fórmula:C17H16FN5O3SPureza:98%Cor e Forma:SolidPeso molecular:389.4Werner syndrome RecQ helicase-IN-3
CAS:<p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>Fórmula:C31H30ClF3N8O5Cor e Forma:SolidPeso molecular:687.07CFM-1
CAS:<p>CFM-1 is an antagonist of the anaphase-promoting complex (APC)-2. It also is a cell cycle and apoptosis regulatory protein (CARP)-1 interaction antagonist.</p>Fórmula:C12H7BrN2O2S2Pureza:98%Cor e Forma:SolidPeso molecular:355.23Mps-BAY2b
CAS:<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Fórmula:C20H23N5OCor e Forma:SolidPeso molecular:349.43Indirubin-5-sulfonate
CAS:<p>Indirubin-5-sulfonate inhibits GSK-3β & CDKs with IC50: 55/35/150/300/65 nM for CDK1/B, 2/A&E, 4/D1, 5/p35.</p>Fórmula:C16H10N2O5SPureza:98%Cor e Forma:SolidPeso molecular:342.33RUC-1
CAS:<p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>Fórmula:C11H15N5OSPureza:98%Cor e Forma:SolidPeso molecular:265.33Homocarbonyltopsentin
CAS:<p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>Fórmula:C21H14N4O3Pureza:98%Cor e Forma:SolidPeso molecular:370.36Guanoctine hydrochloride
CAS:<p>Guanoctine hydrochloride has antihypertensive activity.</p>Fórmula:C9H22ClN3Cor e Forma:SolidPeso molecular:207.74NSC 109555 ditosylate
CAS:<p>Chk2 inhibitor,ATP-competitive</p>Fórmula:C26H32N10O4SPureza:98%Cor e Forma:SolidPeso molecular:580.6614α-Demethylase/DNA Gyrase-IN-2
CAS:<p>14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.</p>Fórmula:C24H22N4O4Cor e Forma:SolidPeso molecular:430.46BDM44768
CAS:<p>BDM44768 is an insulin-degrading enzyme (IDE) inhibitor that acts by inducing glucose intolerance.</p>Fórmula:C24H22FN5O3Cor e Forma:SolidPeso molecular:447.46IRE1α kinase-IN-3
CAS:<p>IRE1α kinase-IN-3 is a potent, ATP-competitive inhibitor of IRE1α (Ki: 480 nM).</p>Fórmula:C29H32N6O3SCor e Forma:SolidPeso molecular:544.67Mps1-IN-4
CAS:<p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>Fórmula:C26H31F3N6O2Cor e Forma:SolidPeso molecular:516.56CDK7-IN-8
CAS:<p>CDK7-IN-8 is a potent inhibitor of CDK7 (IC50: 54.29 nM) and exhibits inhibitory activity against several cancer cells and in vivo tumor models.</p>Fórmula:C25H38N8O3Cor e Forma:SolidPeso molecular:498.62Nucleoside-Analog-2
CAS:<p>Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.</p>Fórmula:C9H11N5O6Pureza:98%Cor e Forma:SolidPeso molecular:285.212'-Deoxy-L-guanosine
CAS:<p>2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death.</p>Fórmula:C10H13N5O4Cor e Forma:SolidPeso molecular:267.24VE-465
CAS:<p>VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.</p>Fórmula:C22H28N8OSCor e Forma:SolidPeso molecular:452.58Antitumor agent-85
<p>Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.</p>Fórmula:C24H33N7Cor e Forma:SolidPeso molecular:419.57XU1
CAS:<p>XU1（Benzo[c][1,8]naphthyridin-6(5h)-One） is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition, regulation or</p>Fórmula:C12H8N2OPureza:98.58% - 99.59%Cor e Forma:SolidPeso molecular:196.2HBV-IN-15
CAS:<p>HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.</p>Fórmula:C24H23ClO6Cor e Forma:SolidPeso molecular:442.89PD-1-IN-22
CAS:<p>PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).</p>Fórmula:C25H25N5O4Pureza:99.51%Cor e Forma:SolidPeso molecular:459.5TC-Mps1-12
CAS:<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Fórmula:C17H20N6OPureza:98%Cor e Forma:SolidPeso molecular:324.38CB 3717
CAS:<p>CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.</p>Fórmula:C24H23N5O6Cor e Forma:SolidPeso molecular:477.47Pyrazofurin
CAS:<p>Pyrazofurin, a pyrimidine analogue, blocks cell growth and DNA synthesis by targeting UMP synthase & orotate-phosphoribosyltransferase (IC50: 0.06-0.37 μM).</p>Fórmula:C9H13N3O6Pureza:98%Cor e Forma:SolidPeso molecular:259.22IPR-803
CAS:<p>IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.</p>Fórmula:C27H23N3O4Pureza:95%Cor e Forma:SolidPeso molecular:453.49Datelliptium chloride
CAS:<p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>Fórmula:C23H28ClN3OPureza:98%Cor e Forma:SolidPeso molecular:397.94Sibrafiban
CAS:<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Fórmula:C20H28N4O6Cor e Forma:SolidPeso molecular:420.46CFI-400437
CAS:<p>CFI-400437 is an ATP-competitive PLK4 inhibitor (IC50: 0.6 nM) and is an indolequinone derivative.</p>Fórmula:C29H28N6O2Cor e Forma:SolidPeso molecular:492.57IACS-4759
CAS:<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Fórmula:C10H17N3O2Cor e Forma:SolidPeso molecular:211.26FINDY
CAS:<p>FINDY selectively inhibits DYRK1A at 35 μM IC50, blocking Ser97 autophosphorylation, useful for neurological disorder research.</p>Fórmula:C16H17NO2S2SiCor e Forma:SolidPeso molecular:347.53CDK-IN-10
CAS:<p>CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.</p>Fórmula:C18H18N4O2Pureza:97.07%Cor e Forma:SolidPeso molecular:322.36SR7826
CAS:<p>SR7826 is a selective LIMK inhibitor.</p>Fórmula:C22H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:387.43MtTMPK-IN-6
CAS:<p>MtTMPK-IN-6 inhibits M. tuberculosis thymidylate kinase with IC50 of 29 μM, promising for TB research.</p>Fórmula:C23H25N3O3Cor e Forma:SolidPeso molecular:391.46ERCC1-XPF-IN-1
CAS:<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Fórmula:C28H32ClN5O2Cor e Forma:SolidPeso molecular:506.04CLT-28643
CAS:<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Fórmula:C19H17N3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:351.36ML372
CAS:<p>ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.</p>Fórmula:C18H20N2O4SCor e Forma:SolidPeso molecular:360.43BMS-587101
CAS:<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Fórmula:C26H20Cl2N4O4SCor e Forma:SolidPeso molecular:555.43PFM03
CAS:<p>PFM03 is a endonuclease inhibitor that specifically blocks Mre11,reduce MRN endonuclease activity, blocking hMRN-mediated endonucleotomy and nuclear exocytosis.</p>Fórmula:C14H15NO2S2Pureza:99.81% - 99.98%Cor e Forma:SolidPeso molecular:293.4c-Myc inhibitor 9
CAS:<p>c-Myc inhibitor 9 (compound 332) with logEC50 ≥6, suppresses tumors in mice, useful for cancer research.</p>Fórmula:C27H31N5OSCor e Forma:SolidPeso molecular:473.63CDK7-IN-20
<p>CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.</p>Fórmula:C30H26N6O3Cor e Forma:SolidPeso molecular:518.57Integrin modulator 1
CAS:<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Fórmula:C13H14N2O4Pureza:99.61%Cor e Forma:SolidPeso molecular:262.26EMD534085
CAS:<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Fórmula:C25H31F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:476.53Chrysotobibenzyl
CAS:<p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>Fórmula:C19H24O5Cor e Forma:SolidPeso molecular:332.39XMD-17-51
CAS:<p>XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.</p>Fórmula:C21H24N8OPureza:99.04%Cor e Forma:SoildPeso molecular:404.478RK64
CAS:<p>8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .</p>Fórmula:C14H16N8O2SCor e Forma:SolidPeso molecular:360.45,10-Dideazafolic acid
CAS:<p>5,10-Dideazafolic acid is an antileukemic drug.</p>Fórmula:C21H21N5O6Cor e Forma:SolidPeso molecular:439.42CDK7-IN-13
CAS:<p>CDK7-IN-13: A potent pyrimidine-based CDK7 inhibitor, potential for various cancers. See CN114249712A.</p>Fórmula:C20H23F3N6OSPureza:99.22%Cor e Forma:SolidPeso molecular:452.5Indirubin-3'-monoxime-5-sulphonic acid
CAS:<p>Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.</p>Fórmula:C16H11N3O5SPureza:98%Cor e Forma:SolidPeso molecular:357.3410-Deazaaminopterin
CAS:<p>10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.</p>Fórmula:C20H21N7O5Cor e Forma:SolidPeso molecular:439.42Antibacterial agent 89
CAS:<p>Antibacterial agent 89 blocks bacterial transcription and clostridial cytotoxins, inhibiting β'CH-σ interactions.</p>Fórmula:C21H10Cl2F3NO5SCor e Forma:SolidPeso molecular:516.27P1788
CAS:<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Fórmula:C15H17NO3Cor e Forma:SolidPeso molecular:259.3Cdc7-IN-7c
CAS:<p>Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.</p>Fórmula:C15H17N5OSPureza:98.19% - 99.22%Cor e Forma:SolidPeso molecular:315.39AS-0141
CAS:<p>AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM)，具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶，在细胞周期中对 DNA 复制的启动至关重要。</p>Fórmula:C21H22F3N5O4Pureza:99.97%Cor e Forma:SolidPeso molecular:465.43Anticancer agent 73
CAS:<p>Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.</p>Fórmula:C14H15NO4Pureza:99.19%Cor e Forma:SolidPeso molecular:261.27AzddMeC
CAS:<p>AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infection</p>Fórmula:C10H14N6O3Pureza:97.14% - 99.62%Cor e Forma:SolidPeso molecular:266.26ITX3
CAS:<p>ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.</p>Fórmula:C22H17N3OSPureza:99.02%Cor e Forma:SolidPeso molecular:371.45Firategrast
CAS:<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Fórmula:C27H27F2NO6Pureza:99.16%Cor e Forma:SolidPeso molecular:499.5116-9e
CAS:<p>116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.</p>Fórmula:C31H32N2O5Pureza:99.55%Cor e Forma:SolidPeso molecular:512.6D-I03
CAS:<p>D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.</p>Fórmula:C23H36N6SPureza:99.65%Cor e Forma:SolidPeso molecular:428.64CF-1743
CAS:<p>CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication.</p>Fórmula:C22H26N2O5Pureza:99.6% - 99.79%Cor e Forma:SolidPeso molecular:398.45Abemaciclib metabolite M20
CAS:<p>Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂，可用于癌症治疗的相关研究。</p>Fórmula:C27H32F2N8OPureza:98.1% - 99.08%Cor e Forma:SolidPeso molecular:522.59hDHODH-IN-7
CAS:<p>hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.</p>Fórmula:C21H23FN4OPureza:99.87%Cor e Forma:SolidPeso molecular:366.43DS18561882
CAS:<p>DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.</p>Fórmula:C28H31F3N4O6SPureza:98.19% - >99.99%Cor e Forma:SolidPeso molecular:608.63CD532
CAS:<p>CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.</p>Fórmula:C26H25F3N8OPureza:99.49%Cor e Forma:SolidPeso molecular:522.52GKI-1
CAS:<p>GKI-1, a GWL kinase inhibitor: IC50 - 4.9 µM for hGWLFL, 2.5 µM for hGWL-KinDom, 11 µM for ROCK1; weak on PKA.</p>Fórmula:C15H12ClN3Pureza:99.96%Cor e Forma:SolidPeso molecular:269.73Elarofiban
CAS:<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Fórmula:C22H32N4O4Pureza:98.76%Cor e Forma:SolidPeso molecular:416.51CDK9-IN-10
CAS:<p>CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.</p>Fórmula:C22H16O5Pureza:99.8%Cor e Forma:SolidPeso molecular:360.36Galocitabine
CAS:<p>Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.</p>Fórmula:C19H22FN3O8Pureza:99.89%Cor e Forma:SolidPeso molecular:439.39Caracemide
CAS:<p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>Fórmula:C6H11N3O4Pureza:99.8%Cor e Forma:SolidPeso molecular:189.176RK73
CAS:<p>6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).</p>Fórmula:C13H17N5O2SPureza:99.91%Cor e Forma:SolidPeso molecular:307.37GS-6620 PM
CAS:<p>GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.</p>Fórmula:C13H15N5O4Pureza:98.52% - 98.7%Cor e Forma:SolidPeso molecular:305.29CHK1-IN-3
CAS:<p>CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).</p>Fórmula:C20H23N9OPureza:98.78%Cor e Forma:SolidPeso molecular:405.46
