Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(116 produtos)
- CDK(548 produtos)
- Ciclo celular/Parada(5 produtos)
- Chk(48 produtos)
- DYRK(46 produtos)
- Dinamina(27 produtos)
- Ferroptose(233 produtos)
- HSP(180 produtos)
- Integrinas(276 produtos)
- Cinesina(87 produtos)
- LIM Quinase(21 produtos)
- Microtúbulo associado(273 produtos)
- PKC(128 produtos)
- PLK(25 produtos)
- ROCK(61 produtos)
- Rho(6 produtos)
- Wee1(14 produtos)
- c-Myc(77 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3936 produtos de "Ciclo celular/Ponto de verificação"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
DYRKi
CAS:DYRKi is a nontoxic, DYRK1-selective inhibitor.Fórmula:C20H13F3N4O2SCor e Forma:SolidPeso molecular:430.4RUC-1
CAS:RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.Fórmula:C11H15N5OSPureza:98%Cor e Forma:SolidPeso molecular:265.33Homocarbonyltopsentin
CAS:Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.Fórmula:C21H14N4O3Pureza:98%Cor e Forma:SolidPeso molecular:370.36Guanoctine hydrochloride
CAS:Guanoctine hydrochloride has antihypertensive activity.Fórmula:C9H22ClN3Cor e Forma:SolidPeso molecular:207.74Zelpolib
CAS:Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.Fórmula:C22H21N3O5S2Pureza:98.79%Cor e Forma:SolidPeso molecular:471.55Cyclapolin 9
CAS:Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.Fórmula:C9H4F3N3O4SPureza:99.64%Cor e Forma:SolidPeso molecular:307.21Ref: TM-T22700
1mg96,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg319,00€25mg512,00€50mg707,00€100mg964,00€500mg1.935,00€XL-188
CAS:XL-188: Potent, selective USP7 inhibitor, IC50 = 193 nM (domain), 90 nM (full). Boosts p53, p21; degrades HDM2. Unique among DUB inhibitors.Fórmula:C32H42N6O4Cor e Forma:SolidPeso molecular:574.71BIPM
CAS:BIPM inhibits ROCK2, alters SH-SY5Y cell migration, actin fibers, neurite length, and reduces cofilin phosphorylation.Fórmula:C23H22N2O3Cor e Forma:SolidPeso molecular:374.43HIV-1 inhibitor-43
CAS:HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.Fórmula:C24H21ClN2O4SCor e Forma:SolidPeso molecular:468.95RP-106
CAS:RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3.Fórmula:C17H19N3OPureza:98%Cor e Forma:SolidPeso molecular:281.35c-Myc inhibitor 9
CAS:c-Myc inhibitor 9 (compound 332) with logEC50 ≥6, suppresses tumors in mice, useful for cancer research.Fórmula:C27H31N5OSCor e Forma:SolidPeso molecular:473.63Cdc7-IN-4
CAS:Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.Fórmula:C22H24F3N5O4Pureza:98%Cor e Forma:SolidPeso molecular:479.45Valategrast
CAS:Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.Fórmula:C30H32Cl3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:604.95hDHODH-IN-3
CAS:hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Fórmula:C18H19BrN4O2Pureza:99.871%Cor e Forma:SolidPeso molecular:403.27Ref: TM-T11025
500mgA consultar1mg60,00€2mg88,00€5mg133,00€1mL*10mM (DMSO)142,00€10mg203,00€25mg335,00€50mg474,00€100mg623,00€Zaurategrast ethyl ester
CAS:Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.Fórmula:C28H29BrN4O3Pureza:98%Cor e Forma:SolidPeso molecular:549.46BI8622
CAS:BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.Fórmula:C25H26N6OPureza:98.28% - 98.28%Cor e Forma:SolidPeso molecular:426.51PV-1115
CAS:PV-1115 is an effective and highly selective inhibitor of the Chk2.Fórmula:C20H19N7O3Pureza:98%Cor e Forma:SolidPeso molecular:405.41PF-4950834
CAS:PF-4950834, a ATP-competitive, selective Rho kinase inhibitor, provides therapeutic benefits in chronic inflammatory diseases.Fórmula:C21H19N3O2Pureza:98%Cor e Forma:SolidPeso molecular:345.39P18IN003
CAS:P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion ofFórmula:C17H16N2O3Pureza:99%Cor e Forma:SolidPeso molecular:296.32CDK7-IN-20
CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.Fórmula:C30H26N6O3Cor e Forma:SolidPeso molecular:518.57Integrin modulator 1
CAS:Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.Fórmula:C13H14N2O4Pureza:99.61%Cor e Forma:SolidPeso molecular:262.26hDHODH-IN-5
CAS:hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).Fórmula:C21H21F3N2O2Pureza:99.55%Cor e Forma:SolidPeso molecular:390.4Ref: TM-T11029
1mg80,00€5mg158,00€1mL*10mM (DMSO)172,00€10mg221,00€25mg356,00€50mg530,00€100mg755,00€Synucleozid
CAS:Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.Fórmula:C22H20N6Pureza:98%Cor e Forma:SolidPeso molecular:368.43HBV-IN-21
CAS:HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).Fórmula:C17H17FN4OS2Cor e Forma:SolidPeso molecular:376.47FAK/aurora kinase-IN-1
CAS:FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Fórmula:C23H24ClN7O3Cor e Forma:SolidPeso molecular:481.93AS-136A
CAS:AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Fórmula:C17H19F3N4O3SPureza:98.52%Cor e Forma:SolidPeso molecular:416.42Ref: TM-T62160
1mg215,00€5mg537,00€1mL*10mM (DMSO)590,00€10mg802,00€25mg1.369,00€50mg1.783,00€100mg2.395,00€TCS 2314
CAS:TCS 2314, Selective VLA-4 antagonist (IC50=4.4 nM), high clearance/low oral bioavailability, for asthma research.Fórmula:C28H34N4O6Pureza:99.86%Cor e Forma:SolidPeso molecular:522.59Braco-19 trihydrochloride
CAS:BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.Fórmula:C35H46Cl3N7O2Pureza:98.74%Cor e Forma:SolidPeso molecular:703.14Sibrafiban
CAS:Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.Fórmula:C20H28N4O6Cor e Forma:SolidPeso molecular:420.46Trimetrexate glucuronate
CAS:Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.Fórmula:C25H33N5O10Cor e Forma:SolidPeso molecular:563.564CDK9-IN-14
CAS:CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.Fórmula:C21H23F2N3O4Cor e Forma:SolidPeso molecular:419.42BMVC
CAS:BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.Fórmula:C28H25I2N3Cor e Forma:SolidPeso molecular:657.33CDK4/6-IN-7
CAS:CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.Fórmula:C18H18ClN5O3Cor e Forma:SolidPeso molecular:387.82FD-IN-1
CAS:FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Fórmula:C23H23NO4Pureza:98.85%Cor e Forma:SolidPeso molecular:377.43Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Fórmula:C30H33Cl4N3O4Pureza:98%Cor e Forma:SolidPeso molecular:641.41XU1
CAS:XU1（Benzo[c][1,8]naphthyridin-6(5h)-One） is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition, regulation orFórmula:C12H8N2OPureza:97.81% - 99.59%Cor e Forma:SolidPeso molecular:196.2AZD7762 HCl
CAS:AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.Fórmula:C17H20ClFN4O2SPureza:98%Cor e Forma:SolidPeso molecular:398.88DENV-IN-4
CAS:DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.Fórmula:C28H32N4O4SiCor e Forma:SolidPeso molecular:516.66Chrysotobibenzyl
CAS:Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.Fórmula:C19H24O5Cor e Forma:SolidPeso molecular:332.391-Methylcytosine
CAS:1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired withFórmula:C5H7N3OPureza:99.88%Cor e Forma:SolidPeso molecular:125.13WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Fórmula:C13H15BrCl2N2O4SPureza:98.09%Cor e Forma:SolidPeso molecular:446.14Ref: TM-T73295
1mg71,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg236,00€25mg485,00€50mg782,00€100mg1.305,00€KIF18A-IN-4
CAS:KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.Fórmula:C22H27N3O3SCor e Forma:SolidPeso molecular:413.53TP1287
CAS:TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib.Fórmula:C21H21ClNO8PCor e Forma:SolidPeso molecular:481.82Aloisine A
CAS:Aloisine A, a CDK/GSK-3 inhibitor with IC50: Cdk1/B-150nM, Cdk2/A-120nM, Cdk2/E-400nM, Cdk5/25-200nM, Cdk5/35-160nM, GSK-3α-500nM, GSK-3β-650nM, JNK-3-10μM.Fórmula:C16H17N3OPureza:98%Cor e Forma:SolidPeso molecular:267.33DHX9-IN-1
CAS:DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].Fórmula:C21H21F2N5O3SCor e Forma:SolidPeso molecular:461.49Ref: TM-T82569
1mg205,00€5mg528,00€1mL*10mM (DMSO)537,00€10mg782,00€25mg1.161,00€50mg1.558,00€100mg2.322,00€TDRL-551
CAS:TDRL-551 is a novel and potent replication protein A (RPA) inhibitor (IC50=18 µM) with potential anticancer activity.TDRL-551 inhibits RPA-DNA interaction andFórmula:C25H23ClIN3O4Pureza:98.09%Cor e Forma:SolidPeso molecular:591.83Ref: TM-T28935
1mg73,00€5mg160,00€1mL*10mM (DMSO)202,00€10mg250,00€25mg505,00€50mg803,00€100mg1.288,00€BPKDi
CAS:BPKDi is a potent and selective inhibitor of PKD (protein kinase D).Fórmula:C21H28N6OPureza:98%Cor e Forma:SolidPeso molecular:380.49Enocitabine
CAS:Enocitabine is a nucleoside analog.Fórmula:C31H55N3O6Pureza:97.22%Cor e Forma:SolidPeso molecular:565.788RK64
CAS:8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .Fórmula:C14H16N8O2SCor e Forma:SolidPeso molecular:360.4CDK7-IN-16
CAS:CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.Fórmula:C19H21F3N6O2SCor e Forma:SolidPeso molecular:454.47ANI-7
CAS:ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).Fórmula:C13H8Cl2N2Pureza:99.07%Cor e Forma:SolidPeso molecular:263.12Ref: TM-T10325
1mL*10mM (DMSO)33,00€5mg38,00€10mg62,00€25mg105,00€50mg164,00€100mg222,00€200mg330,00€CDK7-IN-10
CAS:CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)Fórmula:C29H35N7O3Cor e Forma:SolidPeso molecular:529.63Piposulfan
CAS:Piposulfan, a water-insoluble alkylating agent, is used as an antineoplastic and anti-tumor agent.Fórmula:C12H22N2O8S2Cor e Forma:SolidPeso molecular:386.44MMV688844
CAS:MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.Fórmula:C23H25ClN4O2Cor e Forma:SolidPeso molecular:424.92Valomaciclovir
CAS:Valomaciclovir is a DNA polymerase inhibitor potentially for treatment of acute herpes zoster and EB virus infection.Fórmula:C15H24N6O4Cor e Forma:SolidPeso molecular:352.39IDD388
CAS:IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Fórmula:C16H12BrClFNO4Pureza:99.56%Cor e Forma:SolidPeso molecular:416.63Thiarabine
CAS:Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.Fórmula:C9H13N3O4SPureza:98%Cor e Forma:SolidPeso molecular:259.28REV7/REV3L-IN-1
CAS:REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),Fórmula:C19H21N3O3SPureza:98%Cor e Forma:SolidPeso molecular:371.45CH-1504
CAS:CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.Fórmula:C23H23N5O5Cor e Forma:SolidPeso molecular:449.46ATB107
CAS:ATB107 is a potent and novel inhibitor of indole-3-glycerol phosphate synthase (IGPS, KD: 3 μM).Fórmula:C21H28N8Pureza:98%Cor e Forma:SolidPeso molecular:392.5NSC47924
CAS:NSC47924 is a laminin receptor (LR) inhibitor.Fórmula:C18H17NO2Pureza:98%Cor e Forma:SolidPeso molecular:279.33AB-182
CAS:AB-182 is an aziridine derivative with antitumor activity.Fórmula:C11H22N3O4PCor e Forma:SolidPeso molecular:291.28GW8510
CAS:GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.Fórmula:C21H15N5O3S2Pureza:99.32%Cor e Forma:SolidPeso molecular:449.51CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Fórmula:C16H18N2O7SPureza:99.95%Cor e Forma:SolidPeso molecular:382.39Ro 43-5054
CAS:Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.Fórmula:C24H27N5O7Pureza:98%Cor e Forma:SolidPeso molecular:497.5ROCK-IN-D1
CAS:ROCK-IN-D1 is an effective and selective inhibitor of ROCK.Fórmula:C22H27N5O2SPureza:98%Cor e Forma:SolidPeso molecular:425.55DHODH-IN-4
CAS:DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Fórmula:C17H12Cl2N2O2Pureza:99.34%Cor e Forma:SolidPeso molecular:347.2Ref: TM-T11027
1mg109,00€2mg163,00€5mg243,00€1mL*10mM (DMSO)248,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mg2.035,00€PD 130883
CAS:PD 130883 is a potent lipophilic quinazoline antifolate.Fórmula:C18H15N5O3Pureza:98%Cor e Forma:SolidPeso molecular:349.34Mycro2
CAS:Mycro2 is an inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max.Fórmula:C17H11F3N4OS2Cor e Forma:SolidPeso molecular:408.42Nitracrine dihydrochloride
CAS:Nitracrine dihydrochloride is an acridine antineoplastic agent used in mammary and ovarian tumors. It inhibits RNA synthesis.Fórmula:C18H22Cl2N4O2Cor e Forma:SolidPeso molecular:397.3SNX2-1-108
CAS:SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.Fórmula:C21H16N4Pureza:98%Cor e Forma:SolidPeso molecular:324.38SPC-839
CAS:SPC-839 is an IKK-2 Inhibitor with oral activity.Fórmula:C18H14N4O3SCor e Forma:SolidPeso molecular:366.39APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Fórmula:C22H28N6O4Pureza:99.8%Cor e Forma:SolidPeso molecular:440.5ARN22089
CAS:ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.Fórmula:C23H27N5Pureza:98.37%Cor e Forma:SolidPeso molecular:373.49Ref: TM-T85727
1mg109,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg385,00€25mg647,00€50mg964,00€100mg1.431,00€200mg1.963,00€Metralindole
CAS:Metralindole is a reversible inhibitor of monoamine oxidase A (RIMA).Fórmula:C15H17N3OCor e Forma:SolidPeso molecular:255.32CDK2-IN-11
CAS:CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.Fórmula:C18H14ClN7O2SCor e Forma:SolidPeso molecular:427.87MTH1-IN-2
CAS:MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.Fórmula:C24H27N3O5SPureza:98%Cor e Forma:SolidPeso molecular:469.55CBL 0100 free base
CAS:CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Fórmula:C24H26N2O2Pureza:98.18% - 98.86%Cor e Forma:SolidPeso molecular:374.48LIMK-IN-14
CAS:LIMK-IN-14 is an effective and selective inhibitor of LIMK.Fórmula:C22H27N7O3Pureza:98%Cor e Forma:SolidPeso molecular:437.49Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Fórmula:C7H4O3S2Pureza:98.50%Cor e Forma:White To Off-White PowderPeso molecular:200.23TDRL-X80
CAS:TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).Fórmula:C23H15ClN2O6Cor e Forma:SolidPeso molecular:450.83Laromustine
CAS:Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Fórmula:C6H14ClN3O5S2Pureza:≥98%Cor e Forma:SolidPeso molecular:307.78Tripolin A
CAS:Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)Fórmula:C15H11NO3Pureza:98%Cor e Forma:SolidPeso molecular:253.25CLK1-IN-2
CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.Fórmula:C16H12Cl2N2O2SCor e Forma:SolidPeso molecular:367.25hDHODH-IN-4
CAS:hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.Fórmula:C21H24N4O2Pureza:99.87%Cor e Forma:SolidPeso molecular:364.44Akt1&PKA-IN-1
CAS:Akt1&PKA-IN-1 inhibits Akt/PKA: IC50 = 0.03μM (PKAa), 0.11μM (Akt), 9.8μM (CDK2); selective for CDK2.Fórmula:C20H17Cl2N3OCor e Forma:SolidPeso molecular:386.27BMH-22
CAS:BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Fórmula:C16H17N3Cor e Forma:SolidPeso molecular:251.33Codon readthrough inducer 1
CAS:Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.Fórmula:C15H11N3O5Pureza:98%Cor e Forma:SolidPeso molecular:313.26BMS-986463
CAS:BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD). BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC).Fórmula:C32H33FN4O5Cor e Forma:SolidPeso molecular:572.63Cylindrospermopsin
CAS:Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.Fórmula:C15H21N5O7SCor e Forma:SolidPeso molecular:415.42MS0017509
CAS:MS0017509 is a DNA damage repair inhibitor.Fórmula:C11H10N4Pureza:98%Cor e Forma:SolidPeso molecular:198.22DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Fórmula:C17H13ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:312.75LCAHA
CAS:LCAHA is a USP2a inhibitor. LCAHA inhibits growth of cyclin D1-dependent cells.Fórmula:C24H41NO3Cor e Forma:SolidPeso molecular:391.59Fosteabine
CAS:Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.Fórmula:C27H50N3O8PPureza:98%Cor e Forma:SolidPeso molecular:575.67WF-536 Hydrochloride
CAS:WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.Fórmula:C14H16ClN3OCor e Forma:SolidPeso molecular:277.75CRT-0105446
CAS:CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Fórmula:C20H18F3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:421.44AnnH31
CAS:AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm theFórmula:C15H13N3OPureza:99.99%Cor e Forma:SolidPeso molecular:251.282'-Deoxy-L-guanosine
CAS:2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death.Fórmula:C10H13N5O4Cor e Forma:SolidPeso molecular:267.24Flurocitabine
CAS:Flurocitabine is a therapeutic agent with antineoplastic activity.Fórmula:C9H10FN3O4Pureza:98%Cor e Forma:SolidPeso molecular:243.19Crozbaciclib fumarate
CAS:Crozbaciclib fumarate is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively.Fórmula:C32H34F2N6O4Cor e Forma:SolidPeso molecular:604.65
