Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(116 produtos)
- CDK(548 produtos)
- Ciclo celular/Parada(5 produtos)
- Chk(49 produtos)
- DYRK(46 produtos)
- Dinamina(27 produtos)
- Ferroptose(233 produtos)
- HSP(180 produtos)
- Integrinas(276 produtos)
- Cinesina(87 produtos)
- LIM Quinase(21 produtos)
- Microtúbulo associado(274 produtos)
- PKC(128 produtos)
- PLK(25 produtos)
- ROCK(61 produtos)
- Rho(6 produtos)
- Wee1(14 produtos)
- c-Myc(77 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3937 produtos de "Ciclo celular/Ponto de verificação"
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Mps-BAY2b
CAS:Mps-BAY2b is a novel MPS1 inhibitor.Fórmula:C20H23N5OCor e Forma:SolidPeso molecular:349.43Indirubin-5-sulfonate
CAS:Indirubin-5-sulfonate inhibits GSK-3β & CDKs with IC50: 55/35/150/300/65 nM for CDK1/B, 2/A&E, 4/D1, 5/p35.Fórmula:C16H10N2O5SPureza:98%Cor e Forma:SolidPeso molecular:342.33DDD100097
CAS:DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.Fórmula:C22H30Cl2F2N4O2SPureza:98.89%Cor e Forma:SolidPeso molecular:523.47NSC 109555 ditosylate
CAS:Chk2 inhibitor,ATP-competitiveFórmula:C26H32N10O4SPureza:98%Cor e Forma:SolidPeso molecular:580.6614α-Demethylase/DNA Gyrase-IN-2
CAS:14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.Fórmula:C24H22N4O4Cor e Forma:SolidPeso molecular:430.46BDM44768
CAS:BDM44768 is an insulin-degrading enzyme (IDE) inhibitor that acts by inducing glucose intolerance.Fórmula:C24H22FN5O3Cor e Forma:SolidPeso molecular:447.46Lysine-methotrexate
CAS:Lysine-methotrexate is an anticancer drug. It is an inhibitor of dihydrofolate reductase.Fórmula:C21H27N9O3Pureza:98%Cor e Forma:SolidPeso molecular:453.5Mps1-IN-4
CAS:Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.Fórmula:C26H31F3N6O2Cor e Forma:SolidPeso molecular:516.56CDK7-IN-8
CAS:CDK7-IN-8 is a potent inhibitor of CDK7 (IC50: 54.29 nM) and exhibits inhibitory activity against several cancer cells and in vivo tumor models.Fórmula:C25H38N8O3Cor e Forma:SolidPeso molecular:498.622'-Deoxy-L-guanosine
CAS:2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death.Fórmula:C10H13N5O4Cor e Forma:SolidPeso molecular:267.24ProTAME
CAS:ProTAME inhibits APC/CFzr & APC/CCdc20, enhances cell death with doxorubicin/etoposide in primary/MM cells, especially after TOPIIα upregulation.Fórmula:C34H38N4O12SPureza:98%Cor e Forma:SolidPeso molecular:726.75USP28-IN-3
CAS:USP28-IN-3 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.Fórmula:C23H20Cl2N2O3SPureza:99.92%Cor e Forma:SolidPeso molecular:475.39Nitracrine
CAS:Nitracrine: a 1-nitroacridine, hypoxia-selective, anti-tumor agent; inhibits RNA synthesis, binds DNA reversibly and forms covalent adducts.Fórmula:C18H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:324.38GR 144053 trihydrochloride
CAS:platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFórmula:C18H30Cl3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:454.82SRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Fórmula:C27H21FN2O3SPureza:98%Cor e Forma:SolidPeso molecular:472.53Levoleucovorin disodium
CAS:Levoleucovorin disodium is the sodium salt of the enantiomerically active form of Folinic Acid.Fórmula:C20H21N7Na2O7Pureza:98%Cor e Forma:SolidPeso molecular:517.41VE-465
CAS:VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.Fórmula:C22H28N8OSCor e Forma:SolidPeso molecular:452.58Antitumor agent-85
Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.Fórmula:C24H33N7Cor e Forma:SolidPeso molecular:419.57USP28-IN-4
CAS:USP28-IN-4 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.Fórmula:C22H18Cl2N2O3SPureza:98.48%Cor e Forma:SolidPeso molecular:461.36FT827
CAS:FT827 is a covalent inhibitor of USP7 that targets the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research.Fórmula:C27H28N6O5SPureza:98.76%Cor e Forma:SolidPeso molecular:548.61I-138
CAS:I-138 is an orally active and reversible inhibitor of USP1-UAF1.I-138 induces mono-ubiquitination of FANCD2 and PCNA and inhibits USP1 auto-cleavage in cells.Fórmula:C26H23F3N6OPureza:99.41%Cor e Forma:SolidPeso molecular:492.5Ref: TM-T73560
1mg170,00€5mg349,00€1mL*10mM (DMSO)384,00€10mg492,00€25mg707,00€50mg982,00€100mg1.468,00€Cdc7-IN-9
CAS:Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].Fórmula:C15H17N5OSCor e Forma:SolidPeso molecular:315.39HBV-IN-15
CAS:HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.Fórmula:C24H23ClO6Cor e Forma:SolidPeso molecular:442.89LIMK1 inhibitor BMS-4
CAS:BMS-4 is a LIMK inhibitor targeting LIMK1/2, reduces cofilin phosphorylation, noncytotoxic to A549 cells.Fórmula:C23H23N7O2SCor e Forma:SolidPeso molecular:461.54Bofumustine
CAS:Bofumustine is a chloroethyl nitrosourea with anti tumor properties.Fórmula:C18H21ClN4O9Cor e Forma:SolidPeso molecular:472.83CB 3717
CAS:CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.Fórmula:C24H23N5O6Cor e Forma:SolidPeso molecular:477.47(S)-LY3177833 hydrate
CAS:(S)-LY3177833 ((S)-Example 2) hydrate, an orally active CDC7 kinase inhibitor, exhibits extensive in vitro anticancer efficacy.Fórmula:C16H14FN5O2Cor e Forma:SolidPeso molecular:327.31CDK2-IN-11
CAS:CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.Fórmula:C18H14ClN7O2SCor e Forma:SolidPeso molecular:427.87BMVC
CAS:BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.Fórmula:C28H25I2N3Cor e Forma:SolidPeso molecular:657.33Sibrafiban
CAS:Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.Fórmula:C20H28N4O6Cor e Forma:SolidPeso molecular:420.46hDHODH-IN-3
CAS:hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Fórmula:C18H19BrN4O2Pureza:99.871%Cor e Forma:SolidPeso molecular:403.27Ref: TM-T11025
500mgA consultar1mg60,00€2mg88,00€5mg133,00€1mL*10mM (DMSO)142,00€10mg203,00€25mg335,00€50mg474,00€100mg623,00€(S)-CR8
CAS:(S)-CR8 is an effective second-generation cyclin-dependent kinase inhibitor.Fórmula:C24H29N7OCor e Forma:SolidPeso molecular:431.53IACS-4759
CAS:IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.Fórmula:C10H17N3O2Cor e Forma:SolidPeso molecular:211.26FINDY
CAS:FINDY selectively inhibits DYRK1A at 35 μM IC50, blocking Ser97 autophosphorylation, useful for neurological disorder research.Fórmula:C16H17NO2S2SiCor e Forma:SolidPeso molecular:347.53DHODH-IN-13
CAS:DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.Fórmula:C10H6F3N3O3Pureza:99.66%Cor e Forma:SolidPeso molecular:273.17hDHODH-IN-5
CAS:hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).Fórmula:C21H21F3N2O2Pureza:99.55%Cor e Forma:SolidPeso molecular:390.4Ref: TM-T11029
1mg80,00€5mg158,00€1mL*10mM (DMSO)172,00€10mg221,00€25mg356,00€50mg530,00€100mg755,00€MtTMPK-IN-6
CAS:MtTMPK-IN-6 inhibits M. tuberculosis thymidylate kinase with IC50 of 29 μM, promising for TB research.Fórmula:C23H25N3O3Cor e Forma:SolidPeso molecular:391.46CCT068127
CAS:CCT068127 is a potent CDK2 and CDK9 inhibitor.Fórmula:C19H27N7OCor e Forma:SolidPeso molecular:369.46Digeranyl bisphosphonate
CAS:Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.DigeranylFórmula:C21H34Na4O6P2Pureza:98.5%Cor e Forma:SolidPeso molecular:536.4ERCC1-XPF-IN-1
CAS:ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.Fórmula:C28H32ClN5O2Cor e Forma:SolidPeso molecular:506.04IRE1α kinase-IN-3
CAS:IRE1α kinase-IN-3 is a potent, ATP-competitive inhibitor of IRE1α (Ki: 480 nM).Fórmula:C29H32N6O3SCor e Forma:SolidPeso molecular:544.67ML372
CAS:ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.Fórmula:C18H20N2O4SCor e Forma:SolidPeso molecular:360.43BMS-587101
CAS:BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.Fórmula:C26H20Cl2N4O4SCor e Forma:SolidPeso molecular:555.43L-Fd4A
CAS:L-Fd4A (compound 36) is an adenine derivative with anti-HIV (EC50=1.5μM) and anti-HBV (EC50=1.7μM) effects, low cytotoxicity.Fórmula:C10H10FN5O2Cor e Forma:SolidPeso molecular:251.22Nucleoside-Analog-1
CAS:Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.Fórmula:C9H9N5O5Pureza:98%Cor e Forma:SolidPeso molecular:267.2Nucleoside-Analog-2
CAS:Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.Fórmula:C9H11N5O6Pureza:98%Cor e Forma:SolidPeso molecular:285.21XL-188
CAS:XL-188: Potent, selective USP7 inhibitor, IC50 = 193 nM (domain), 90 nM (full). Boosts p53, p21; degrades HDM2. Unique among DUB inhibitors.Fórmula:C32H42N6O4Cor e Forma:SolidPeso molecular:574.71c-Myc inhibitor 9
CAS:c-Myc inhibitor 9 (compound 332) with logEC50 ≥6, suppresses tumors in mice, useful for cancer research.Fórmula:C27H31N5OSCor e Forma:SolidPeso molecular:473.63CDK7-IN-20
CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.Fórmula:C30H26N6O3Cor e Forma:SolidPeso molecular:518.57Integrin modulator 1
CAS:Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.Fórmula:C13H14N2O4Pureza:99.61%Cor e Forma:SolidPeso molecular:262.26Chrysotobibenzyl
CAS:Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.Fórmula:C19H24O5Cor e Forma:SolidPeso molecular:332.398RK64
CAS:8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .Fórmula:C14H16N8O2SCor e Forma:SolidPeso molecular:360.45,10-Dideazafolic acid
CAS:5,10-Dideazafolic acid is an antileukemic drug.Fórmula:C21H21N5O6Cor e Forma:SolidPeso molecular:439.42TC-Mps1-12
CAS:TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .Fórmula:C17H20N6OPureza:98%Cor e Forma:SolidPeso molecular:324.38CDK7-IN-13
CAS:CDK7-IN-13 (compound 1) is an effective CDK7 inhibitor for investigating cancers associated with transcriptional dysregulation.Fórmula:C20H23F3N6OSPureza:99.22%Cor e Forma:SolidPeso molecular:452.5Indirubin-3'-monoxime-5-sulphonic acid
CAS:Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.Fórmula:C16H11N3O5SPureza:98%Cor e Forma:SolidPeso molecular:357.34Levofloxacin sodium
CAS:Levofloxacin sodium: synthetic antibacterial, stops DNA replication by inhibiting bacterial DNA gyrase.Fórmula:C18H20FN3NaO4Pureza:98%Cor e Forma:SolidPeso molecular:384.363Datelliptium chloride
CAS:Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.Fórmula:C23H28ClN3OPureza:98%Cor e Forma:SolidPeso molecular:397.94Antibacterial agent 89
CAS:Antibacterial agent 89 blocks bacterial transcription and clostridial cytotoxins, inhibiting β'CH-σ interactions.Fórmula:C21H10Cl2F3NO5SCor e Forma:SolidPeso molecular:516.27P1788
CAS:P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].Fórmula:C15H17NO3Cor e Forma:SolidPeso molecular:259.3DENV-IN-7
CAS:DENV-IN-7, a flavone analog, inhibits dengue virus at 70 nM EC50 with low toxicity to normal cells.Fórmula:C24H22O8Cor e Forma:SolidPeso molecular:438.43BSJ-01-175
CAS:BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.Fórmula:C30H33ClN6O2Cor e Forma:SolidPeso molecular:545.08CDK4/6-IN-12
CAS:CDK4/6-IN-12 inhibits CDK4/6 with IC50s of 592.3 nM & 3090 nM, useful in cancer research.Fórmula:C12H10N6Cor e Forma:SolidPeso molecular:238.25DNA Gyrase-IN-5
CAS:DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.Fórmula:C25H15BrClN5Cor e Forma:SolidPeso molecular:500.78Syntelin
CAS:Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.Fórmula:C21H20N6O2S3Cor e Forma:SolidPeso molecular:484.62Kira8 Hydrochloride
CAS:Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.Fórmula:C31H30Cl2N6O3SPureza:98%Cor e Forma:SolidPeso molecular:637.58SC-203885
CAS:SC-203885 is a checkpoint kinase 2 inhibitor.Fórmula:C15H13N5O2Pureza:98%Cor e Forma:SolidPeso molecular:295.3Zalunfiban
CAS:RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.Fórmula:C16H18N8O2SCor e Forma:SolidPeso molecular:386.43MDK6204
CAS:MDK6204 is a selective inhibitor of CLK1 and CLK2.Fórmula:C20H20N6OPureza:98%Cor e Forma:SolidPeso molecular:360.41hDHODH-IN-4
CAS:hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.Fórmula:C21H24N4O2Pureza:99.87%Cor e Forma:SolidPeso molecular:364.44Cylindrospermopsin
CAS:Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.Fórmula:C15H21N5O7SCor e Forma:SolidPeso molecular:415.42AnnH31
CAS:AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm theFórmula:C15H13N3OPureza:99.99%Cor e Forma:SolidPeso molecular:251.28CAY10746
CAS:CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.Fórmula:C26H23N3O5Pureza:99.71%Cor e Forma:SolidPeso molecular:457.48Ref: TM-T36196
2mg34,00€5mg54,00€1mL*10mM (DMSO)54,00€10mg86,00€25mg172,00€50mg260,00€100mg411,00€200mg552,00€CLT-28643
CAS:CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.Fórmula:C19H17N3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:351.36PFM03
CAS:PFM03 is a endonuclease inhibitor that specifically blocks Mre11,reduce MRN endonuclease activity, blocking hMRN-mediated endonucleotomy and nuclear exocytosis.Fórmula:C14H15NO2S2Pureza:99.81% - 99.98%Cor e Forma:SolidPeso molecular:293.4Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Fórmula:C13H11ClFN5Cor e Forma:SolidPeso molecular:291.71IRE1α kinase-IN-7
CAS:IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmicFórmula:C28H25F3N6OCor e Forma:SolidPeso molecular:518.53WF-536 Hydrochloride
CAS:WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.Fórmula:C14H16ClN3OCor e Forma:SolidPeso molecular:277.75BA-1049
CAS:BA-1049 is a selective ROCK2 inhibitor.Fórmula:C16H21N3O2SCor e Forma:SolidPeso molecular:319.42XMD-12
CAS:XMD-12 is a selective pan-Aurora Kinase inhibitor, with an IC50 of 5.6/18.4/24.6 nM for Aurora A/B/C, anti-tumor, promote the apoptosis of cancer cells.Fórmula:C24H26N6O2Pureza:99.94%Cor e Forma:SolidPeso molecular:430.5CDK8-IN-10
CAS:CDK8-IN-10 is a selective and potent inhibitor of cell cycle protein-dependent kinase (CDK8) (IC50: 8.25 nM) that can be used to study cancer.Fórmula:C25H15ClF3N5O3Cor e Forma:SolidPeso molecular:525.87A 65282
CAS:A 65282: antibacterial isothiazoloquinolone, inhibits P4-unknotting, causes DNA breaks via topoisomerase II.Fórmula:C17H16F2N4O2SPureza:98%Cor e Forma:SolidPeso molecular:378.4XIE18-6
CAS:XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.Fórmula:C18H15NO6SPureza:99.712%Cor e Forma:SolidPeso molecular:373.38CI-898 HCl
CAS:CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.Fórmula:C19H26Cl3N5O3Cor e Forma:SolidPeso molecular:478.8CDK4/6-IN-14
CAS:CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.Fórmula:C24H27ClFN7OCor e Forma:SolidPeso molecular:483.97Trimetrexate glucuronate
CAS:Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.Fórmula:C25H33N5O10Cor e Forma:SolidPeso molecular:563.564TCS 2314
CAS:TCS 2314, Selective VLA-4 antagonist (IC50=4.4 nM), high clearance/low oral bioavailability, for asthma research.Fórmula:C28H34N4O6Pureza:99.86%Cor e Forma:SolidPeso molecular:522.59RP-106
CAS:RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3.Fórmula:C17H19N3OPureza:98%Cor e Forma:SolidPeso molecular:281.35PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Fórmula:C29H36ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:554.08ROCK-IN-4
CAS:ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.Fórmula:C20H26ClFN4O7SCor e Forma:SolidPeso molecular:520.96USP28-IN-2
CAS:USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.Fórmula:C23H20Cl2N2O3SCor e Forma:SolidPeso molecular:475.39PD 130883
CAS:PD 130883 is a potent lipophilic quinazoline antifolate.Fórmula:C18H15N5O3Pureza:98%Cor e Forma:SolidPeso molecular:349.34Apricitabine
CAS:Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-Fórmula:C8H11N3O3SPureza:99.45%Cor e Forma:SolidPeso molecular:229.26Ref: TM-T14313
1mg283,00€5mg507,00€1mL*10mM (DMSO)592,00€10mg628,00€25mg962,00€50mg1.601,00€100mg2.682,00€Cyclapolin 9
CAS:Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.Fórmula:C9H4F3N3O4SPureza:99.64%Cor e Forma:SolidPeso molecular:307.21Ref: TM-T22700
1mg96,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg319,00€25mg512,00€50mg707,00€100mg964,00€500mg1.935,00€1-Methylcytosine
CAS:1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired withFórmula:C5H7N3OPureza:99.88%Cor e Forma:SolidPeso molecular:125.13ANI-7
CAS:ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).Fórmula:C13H8Cl2N2Pureza:99.07%Cor e Forma:SolidPeso molecular:263.12Ref: TM-T10325
1mL*10mM (DMSO)33,00€5mg38,00€10mg62,00€25mg105,00€50mg164,00€100mg222,00€200mg330,00€ROCK-IN-D2
CAS:ROCK-IN-D2 is an effective and selective inhibitor of ROCK.Fórmula:C22H28N6OPureza:98%Cor e Forma:SolidPeso molecular:392.5JH-XIV-68-3
CAS:JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.Fórmula:C21H17F3N8OCor e Forma:SolidPeso molecular:454.41Akt1&PKA-IN-2
CAS:Akt1&PKA-IN-2 ((R)-29) inhibits AKT1, PKAα, CDK2 with IC50s: 0.007, 0.01, 0.69 µM respectively.Fórmula:C20H17Cl2N3OCor e Forma:SolidPeso molecular:386.27CDK1-IN-1
CAS:CDK1-IN-7 inhibits CDK1 at 161.2 nM, triggers p53-dependent apoptosis, and selectively targets tumor growth.Fórmula:C27H23N5O3Cor e Forma:SolidPeso molecular:465.5
