Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(116 produtos)
- CDK(548 produtos)
- Ciclo celular/Parada(5 produtos)
- Chk(49 produtos)
- DYRK(46 produtos)
- Dinamina(27 produtos)
- Ferroptose(233 produtos)
- HSP(180 produtos)
- Integrinas(278 produtos)
- Cinesina(87 produtos)
- LIM Quinase(21 produtos)
- Microtúbulo associado(274 produtos)
- PKC(128 produtos)
- PLK(25 produtos)
- ROCK(61 produtos)
- Rho(6 produtos)
- Wee1(14 produtos)
- c-Myc(77 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3939 produtos de "Ciclo celular/Ponto de verificação"
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LY 207702
CAS:LY 207702, a difluorinated purine nucleoside, exhibits antitumor activity in preclinical models.Fórmula:C10H12F2N6O3Pureza:98%Cor e Forma:SolidPeso molecular:302.24CDK7-IN-2
CAS:CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.Fórmula:C26H39N7O3Cor e Forma:SolidPeso molecular:497.63CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Fórmula:C16H18N2O7SPureza:99.95%Cor e Forma:SolidPeso molecular:382.39XVA143
CAS:XVA143 is an integrin α/β I-like allosteric antagonist, inhibits LFA-1 (αLβ2 integrin)-dependent firm adhesion, induces extended conformations of integrins.Fórmula:C25H21Cl2N3O8Pureza:99.94%Cor e Forma:SolidPeso molecular:562.36BAY-958
CAS:BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.Fórmula:C17H16FN5O3SPureza:98%Cor e Forma:SolidPeso molecular:389.4CDK8-IN-7
CAS:CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.Fórmula:C30H40N2Cor e Forma:SolidPeso molecular:428.65CB10-277
CAS:CB10-277 is a synthetic anti-cancer drug related to dacarbazine that alkylates DNA, inhibits DNA replication and repair, and may block DNA synthesis.Fórmula:C9H11N3O2Cor e Forma:SolidPeso molecular:193.2BMVC
CAS:BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.Fórmula:C28H25I2N3Cor e Forma:SolidPeso molecular:657.333'-Deoxyuridine-5'-triphosphate
CAS:3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Fórmula:C9H15N2O14P3Cor e Forma:SolidPeso molecular:468.14WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Fórmula:C13H15BrCl2N2O4SPureza:98.09%Cor e Forma:SolidPeso molecular:446.14Ref: TM-T73295
1mg71,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg236,00€25mg485,00€50mg782,00€100mg1.305,00€Edatrexate
CAS:Edatrexate (CGP 30694), a Methotrexate analog, combats MTX-resistant tumors and researches various cancers.Fórmula:C22H25N7O5Cor e Forma:SolidPeso molecular:467.48HBV-IN-21
CAS:HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).Fórmula:C17H17FN4OS2Cor e Forma:SolidPeso molecular:376.47Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Fórmula:C30H33Cl4N3O4Pureza:98%Cor e Forma:SolidPeso molecular:641.41Codon readthrough inducer 1
CAS:Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.Fórmula:C15H11N3O5Pureza:98%Cor e Forma:SolidPeso molecular:313.26CDK4/6-IN-7
CAS:CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.Fórmula:C18H18ClN5O3Cor e Forma:SolidPeso molecular:387.82MS0017509
CAS:MS0017509 is a DNA damage repair inhibitor.Fórmula:C11H10N4Pureza:98%Cor e Forma:SolidPeso molecular:198.22GR 144053 trihydrochloride
CAS:platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFórmula:C18H30Cl3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:454.82CAY10760
CAS:CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.Fórmula:C28H24ClN3O3Cor e Forma:SolidPeso molecular:485.96UR-2922
CAS:UR-2922: Oral GPIIb/IIIa blocker with <1 nM affinity, slow 90 min k(off), no LIBS or prothrombotic effects.Fórmula:C25H25N7O6Pureza:98%Cor e Forma:SolidPeso molecular:519.51SAR156497
CAS:SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Fórmula:C27H24N4O4Cor e Forma:SolidPeso molecular:468.5DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Fórmula:C22H18ClF6N3O3Cor e Forma:SolidPeso molecular:521.84GSK3182571
CAS:GSK3182571 is a non-speci c kinase inhibitor[1].Fórmula:C25H31ClN8OCor e Forma:SolidPeso molecular:495.02GSK-3008348
CAS:GSK-3008348 is an antagonist of integrin alpha(v)beta6.Fórmula:C29H37N5O2Pureza:99.547%Cor e Forma:SolidPeso molecular:487.64Cdc7-IN-17
CAS:Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].Fórmula:C13H15N5OSCor e Forma:SolidPeso molecular:289.36TH470
CAS:TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,Fórmula:C30H31N5O5S2Cor e Forma:SolidPeso molecular:605.73cp028
CAS:cp028 inhibits pre-mRNA splicing in vitro.Fórmula:C23H17FN2O4Cor e Forma:SolidPeso molecular:404.39hDHODH-IN-3
CAS:hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Fórmula:C18H19BrN4O2Pureza:99.871%Cor e Forma:SolidPeso molecular:403.27Ref: TM-T11025
500mgA consultar1mg60,00€2mg88,00€5mg133,00€1mL*10mM (DMSO)142,00€10mg203,00€25mg335,00€50mg474,00€100mg623,00€CMX-521
CAS:CMX521: an antiviral for norovirus, effective against rotavirus; inhibits viral RNA polymerase.Fórmula:C13H17N5O5Pureza:99.57%Cor e Forma:SolidPeso molecular:323.3Netivudine
CAS:Netivudine, a potent NRTI with anti-varicella activity, treats HIV by inhibiting reverse transcriptase, reducing viral load.Fórmula:C12H14N2O6Pureza:99.78%Cor e Forma:SolidPeso molecular:282.25Antiviral agent 17
CAS:Antiviral agent 17, EC50 0.015 μM in human assay, effective against murine norovirus, may aid infectious/malignant disease research.Fórmula:C11H14N4O4Pureza:99.89%Cor e Forma:SolidPeso molecular:266.25CLK-IN-T3
CAS:CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.Fórmula:C28H30N6O2Pureza:99.61%Cor e Forma:SolidPeso molecular:482.58Ref: TM-T14980
1mg47,00€2mg62,00€5mg92,00€10mg160,00€25mg289,00€50mg505,00€100mg787,00€200mg1.063,00€CQ211
CAS:CQ211 is a potent selective RIOK2 inhibitor, Kd 6.1 nM, effectively inhibits cancer cell line proliferation.Fórmula:C26H22F3N7O2Pureza:97.01% - 98.31%Cor e Forma:SolidPeso molecular:521.49SJB3-019A
CAS:SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 timesFórmula:C16H8N2O3Pureza:99.72%Cor e Forma:SolidPeso molecular:276.25Ref: TM-T12926
1mg77,00€2mg101,00€5mg168,00€10mg253,00€25mg416,00€50mg580,00€100mg783,00€200mg1.054,00€L82
CAS:L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.Fórmula:C11H8ClN5O4Pureza:98.06% - 98.91%Cor e Forma:SolidPeso molecular:309.67Ref: TM-T60753
5mg70,00€1mL*10mM (DMSO)77,00€10mg103,00€25mg187,00€50mg298,00€100mg472,00€500mg1.026,00€6-Hydroxy-DOPA
CAS:6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.
Fórmula:C9H11NO5Pureza:97.78% - 97.95%Cor e Forma:SolidPeso molecular:213.19BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Fórmula:C14H16N2OSPureza:99.84%Cor e Forma:SolidPeso molecular:260.35Ref: TM-T36964
5mg48,00€1mL*10mM (DMSO)50,00€10mg80,00€25mg160,00€50mg264,00€100mg462,00€500mg982,00€CDK8-IN-1
CAS:CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).Fórmula:C11H8F3N3OPureza:98.48%Cor e Forma:SolidPeso molecular:255.2Ref: TM-T10740
1mg87,00€5mg216,00€1mL*10mM (DMSO)240,00€10mg311,00€25mg525,00€50mg707,00€100mg944,00€UMK57
CAS:UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Fórmula:C17H17N3SPureza:99.86%Cor e Forma:SolidPeso molecular:295.4Rho-Kinase-IN-1
CAS:Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.Fórmula:C20H24N4SPureza:99.8%Cor e Forma:SolidPeso molecular:352.5Ref: TM-T12721
1mg71,00€1mL*10mM (DMSO)105,00€5mg138,00€10mg205,00€25mg358,00€50mg502,00€100mg665,00€200mg893,00€Eprociclovir
CAS:Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention ofFórmula:C11H15N5O3Pureza:98.50% - 99.86%Cor e Forma:SolidPeso molecular:265.27Rhodblock 6
CAS:Rhodblock 6 is a Rho kinase inhibitor, blocking phosphorylated MRLC localization by targeting ROCK activity.Fórmula:C12H13N3OPureza:99.87%Cor e Forma:SolidPeso molecular:215.25BioE-1115
CAS:BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).Fórmula:C19H18FN3O2Pureza:97.54%Cor e Forma:SolidPeso molecular:339.36COH34
CAS:COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM.Fórmula:C18H15NOSPureza:99.57%Cor e Forma:SolidPeso molecular:293.38CHD1Li 6.11
CAS:CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.Fórmula:C21H22BrN5OSPureza:99.04%Cor e Forma:SolidPeso molecular:472.4Ref: TM-T63049
1mg96,00€5mg205,00€1mL*10mM (DMSO)215,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€500mg2.205,00€NR2F6 modulator-1
CAS:NR2F6 modulator-1, a potent agent for NR2F6, affects immune response and tumor stem cell activity.Fórmula:C23H17NO5SPureza:98.31%Cor e Forma:SolidPeso molecular:419.45Ref: TM-T62204
1mg87,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg268,00€25mg502,00€50mg703,00€100mg982,00€D-I03
CAS:D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.Fórmula:C23H36N6SPureza:99.65%Cor e Forma:SolidPeso molecular:428.64Ref: TM-T10936
1mg34,00€5mg73,00€1mL*10mM (DMSO)80,00€10mg119,00€25mg236,00€50mg353,00€100mg517,00€200mg737,00€SEL120-34A
CAS:SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.Fórmula:C15H18Br2N4Pureza:99.764% - 99.84%Cor e Forma:SolidPeso molecular:414.14Ref: TM-T10744
1mg612,00€5mg1.529,00€1mL*10mM (DMSO)1.835,00€10mg1.880,00€25mg2.178,00€50mg2.862,00€100mg3.870,00€YK-2-69
CAS:YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.Fórmula:C25H27FN8OSPureza:98.61% - 99.64%Cor e Forma:SolidPeso molecular:506.6DENV-IN-5
CAS:Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.Fórmula:C23H25ClF2N4OSPureza:99.42%Cor e Forma:SolidPeso molecular:478.99Ref: TM-T63143
1mg424,00€1mL*10mM (DMSO)898,00€5mg964,00€10mg1.288,00€25mg1.890,00€50mg2.322,00€100mg3.060,00€TTP-8307
CAS:TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.Fórmula:C27H21FN4OPureza:98.95%Cor e Forma:SolidPeso molecular:436.48Ref: TM-T13221
1mg100,00€5mg236,00€1mL*10mM (DMSO)286,00€10mg380,00€25mg740,00€50mg1.108,00€100mg1.791,00€200mg2.412,00€SB-747651A Dihydrochloride
CAS:SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.Fórmula:C16H24Cl2N8OPureza:98.05%Cor e Forma:SolidPeso molecular:415.32Ref: TM-T9652
500mgA consultar1mg70,00€5mg146,00€1mL*10mM (DMSO)160,00€10mg207,00€25mg349,00€50mg497,00€100mg675,00€10-Formylfolic acid
CAS:10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.Fórmula:C20H19N7O7Pureza:99.97%Cor e Forma:SolidPeso molecular:469.41EHT 1610
CAS:EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.Fórmula:C18H14FN5O2SPureza:98.43%Cor e Forma:SolidPeso molecular:383.4Cdc7-IN-7c
CAS:Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.Fórmula:C15H17N5OSPureza:98.19% - 99.22%Cor e Forma:SolidPeso molecular:315.39Ref: TM-T23867
1mg315,00€1mL*10mM (DMSO)600,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€SJ572403
CAS:SJ572403 inhibits p27 protein, Kd 2.2 mM at D2 subdomain of p27-KID; useful in disordered protein disease research.Fórmula:C13H17N5O2Pureza:99.93%Cor e Forma:SolidPeso molecular:275.31Ref: TM-T16889
1mg39,00€5mg86,00€1mL*10mM (DMSO)92,00€10mg119,00€25mg231,00€50mg371,00€100mg537,00€200mg710,00€(S)-PF-06873600
CAS:(S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.Fórmula:C20H27F2N5O4SPureza:98.59%Cor e Forma:SolidPeso molecular:471.52GRK6-IN-1
CAS:GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Fórmula:C22H23ClN6O2Pureza:99.37%Cor e Forma:SolidPeso molecular:438.91Ref: TM-T62518
1mg54,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€Haspin-IN-3
CAS:Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.
Fórmula:C16H10N2O3Pureza:98.78%Cor e Forma:SolidPeso molecular:278.26TC-S 7005
CAS:TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).Fórmula:C21H17N3O3Pureza:99.516%Cor e Forma:SolidPeso molecular:359.38Ref: TM-T17008
500mgA consultar1mg57,00€2mg84,00€5mg125,00€1mL*10mM (DMSO)138,00€10mg188,00€25mg354,00€50mg532,00€100mg712,00€HA-1004
CAS:HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.Fórmula:C12H15N5O2SPureza:99.56% - 99.63%Cor e Forma:SolidPeso molecular:293.34Caracemide
CAS:Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Fórmula:C6H11N3O4Pureza:99.8%Cor e Forma:SolidPeso molecular:189.17hDHODH-IN-7
CAS:hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Fórmula:C21H23FN4OPureza:99.87%Cor e Forma:SolidPeso molecular:366.43Ref: TM-T11031
1mg115,00€2mg172,00€5mg255,00€1mL*10mM (DMSO)266,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€CHK1-IN-3
CAS:CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).Fórmula:C20H23N9OPureza:98.78%Cor e Forma:SolidPeso molecular:405.46Ref: TM-T10791
1mg168,00€2mg231,00€5mg371,00€1mL*10mM (DMSO)423,00€10mg558,00€25mg868,00€50mg1.153,00€100mg1.575,00€200mg2.125,00€Cdk2 Inhibitor II
CAS:Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Fórmula:C14H11BrN4O3SPureza:97.27%Cor e Forma:SolidPeso molecular:395.236RK73
CAS:6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).Fórmula:C13H17N5O2SPureza:99.91%Cor e Forma:SolidPeso molecular:307.37Ref: TM-T10188
1mg137,00€5mg281,00€1mL*10mM (DMSO)310,00€10mg484,00€25mg782,00€50mg1.071,00€100mg1.431,00€500mg2.898,00€Elarofiban
CAS:Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Fórmula:C22H32N4O4Pureza:98.76%Cor e Forma:SolidPeso molecular:416.51Galocitabine
CAS:Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.Fórmula:C19H22FN3O8Pureza:99.89%Cor e Forma:SolidPeso molecular:439.39dCeMM2
CAS:dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.Fórmula:C16H11ClN6OSPureza:99.68%Cor e Forma:SolidPeso molecular:370.82Ref: TM-T61477
1mg34,00€5mg74,00€1mL*10mM (DMSO)104,00€10mg113,00€25mg236,00€50mg404,00€100mg600,00€500mg1.279,00€SMN-C2
CAS:SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.Fórmula:C24H27N5O2Pureza:99.14%Cor e Forma:SolidPeso molecular:417.5Ref: TM-T73475
1mg105,00€5mg250,00€1mL*10mM (DMSO)268,00€10mg401,00€25mg795,00€50mg982,00€100mg1.324,00€P22074
CAS:P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.Fórmula:C12H9NO3S2Pureza:>99.99%Cor e Forma:SolidPeso molecular:279.33Ref: TM-T28284
1mg137,00€1mL*10mM (DMSO)239,00€5mg314,00€10mg427,00€25mg600,00€50mg798,00€100mg1.099,00€200mg1.468,00€Cytembena
CAS:Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.Fórmula:C11H8BrNaO4Pureza:99.7%Cor e Forma:White PowderPeso molecular:307.07GKI-1
CAS:GKI-1, a GWL kinase inhibitor: IC50 - 4.9 µM for hGWLFL, 2.5 µM for hGWL-KinDom, 11 µM for ROCK1; weak on PKA.Fórmula:C15H12ClN3Pureza:99.96%Cor e Forma:SolidPeso molecular:269.73Ref: TM-T11402
1mg93,00€5mg200,00€1mL*10mM (DMSO)215,00€10mg299,00€25mg485,00€50mg658,00€100mg892,00€hSMG-1 inhibitor 11e
CAS:hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.Fórmula:C26H27N7O3SPureza:99.89%Cor e Forma:SolidPeso molecular:517.6116-9e
CAS:116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.Fórmula:C31H32N2O5Pureza:99.55%Cor e Forma:SolidPeso molecular:512.6Ref: TM-T25770
1mL*10mM (DMSO)34,00€1mg50,00€5mg105,00€10mg170,00€25mg355,00€50mg595,00€100mg862,00€200mg1.153,00€SRX3177
CAS:SRX3177 is a novel and potent inhibitor of BRD4, PI3K and CDK.SRX3177 has potential anticancer activity.Fórmula:C31H32N6O4SPureza:99.16%Cor e Forma:SolidPeso molecular:584.69Ref: TM-T69742
1mg70,00€5mg150,00€1mL*10mM (DMSO)178,00€10mg215,00€25mg358,00€50mg517,00€100mg707,00€DSS30
CAS:DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid secretion to help prevent Alzheimer's.Fórmula:C16H14ClNO3S2Pureza:99.19% - 99.4%Cor e Forma:SolidPeso molecular:367.87Poloxin-2
CAS:Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.Fórmula:C16H15NO3Pureza:99.67%Cor e Forma:SolidPeso molecular:269.3AS-0141
CAS:AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM)，具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶，在细胞周期中对 DNA 复制的启动至关重要。Fórmula:C21H22F3N5O4Pureza:99.97%Cor e Forma:SolidPeso molecular:465.43DIF-3
CAS:DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.Fórmula:C13H17ClO4Pureza:99.57%Cor e Forma:SolidPeso molecular:272.72Ref: TM-T60485
1mg96,00€1mL*10mM (DMSO)205,00€5mg222,00€10mg333,00€25mg557,00€50mg795,00€100mg1.071,00€500mg2.187,00€9-Isopropylolomoucine
CAS:9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.Fórmula:C17H22N6OPureza:99.82%Cor e Forma:SolidPeso molecular:326.4Ref: TM-T23589
1mg315,00€1mL*10mM (DMSO)607,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€AGX51
CAS:AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.Fórmula:C27H29NO4Pureza:97.65%Cor e Forma:OilPeso molecular:431.52Ref: TM-T10268
1mg96,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg334,00€25mg652,00€50mg858,00€100mg1.108,00€200mg1.504,00€Talotrexin ammonium
CAS:Talotrexin ammonium, a non-polyglutamic antifolate, inhibits cancer by targeting DHFR.
Fórmula:C27H30N10O6Pureza:97.49%Cor e Forma:SolidPeso molecular:590.59Ref: TM-T64295
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€Firategrast
CAS:Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFórmula:C27H27F2NO6Pureza:99.67%Cor e Forma:SolidPeso molecular:499.5Ref: TM-TQ0291
1mg44,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg133,00€25mg268,00€50mg439,00€100mg708,00€200mg964,00€Abemaciclib metabolite M20
CAS:Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂，可用于癌症治疗的相关研究。Fórmula:C27H32F2N8OPureza:98.1% - 99.08%Cor e Forma:SolidPeso molecular:522.59OTUB1/USP8-IN-1
CAS:OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung cancer.Fórmula:C22H16ClFN2O4Pureza:98.59%Cor e Forma:SoildPeso molecular:426.83DDRI-18
CAS:DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.Fórmula:C26H20N6Pureza:98%Cor e Forma:SolidPeso molecular:416.48ML 315
CAS:ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.Fórmula:C18H13Cl2N3O2Pureza:99.08%Cor e Forma:SolidPeso molecular:374.22Peldesine
CAS:Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Fórmula:C12H11N5OPureza:99.27% - 99.9%Cor e Forma:SolidPeso molecular:241.25Ref: TM-T12399
1mg108,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg416,00€25mg690,00€50mg964,00€100mg1.305,00€500mg2.592,00€RP-6685
CAS:RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.Fórmula:C22H14F7N5OPureza:99.65%Cor e Forma:SoildPeso molecular:497.37Ref: TM-T60187
1mg84,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg219,00€25mg358,00€50mg510,00€100mg715,00€AzddMeC
CAS:AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infectionFórmula:C10H14N6O3Pureza:97.14% - 99.62%Cor e Forma:SolidPeso molecular:266.26Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Fórmula:C27H21N3O3Pureza:99.22%Cor e Forma:SolidPeso molecular:435.47Ref: TM-T35570
1mg66,00€5mg144,00€1mL*10mM (DMSO)157,00€10mg245,00€25mg492,00€50mg710,00€100mg973,00€ERCC1-XPF-IN-2
CAS:ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).
Fórmula:C15H13Cl2NO3Pureza:98.21%Cor e Forma:SolidPeso molecular:326.17Ref: TM-T60904
2mg40,00€5mg60,00€10mg96,00€25mg187,00€50mg311,00€100mg472,00€200mg658,00€500mg1.026,00€ZIM
CAS:ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.Fórmula:C20H19N3O3Pureza:99.85%Cor e Forma:SolidPeso molecular:349.38CRT0066854 hydrochloride
CAS:CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.Fórmula:C24H27Cl2N5SPureza:99.63%Cor e Forma:SolidPeso molecular:488.48Ref: TM-T10888
1mg57,00€5mg122,00€1mL*10mM (DMSO)146,00€10mg192,00€25mg324,00€50mg459,00€100mg642,00€200mg888,00€ITX3
CAS:ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.Fórmula:C22H17N3OSPureza:97.28%Cor e Forma:SolidPeso molecular:371.45AS 1892802
CAS:AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.Fórmula:C20H19N3O2Pureza:99.86%Cor e Forma:SolidPeso molecular:333.38Ref: TM-T22037
1mg49,00€5mg92,00€1mL*10mM (DMSO)109,00€10mg166,00€25mg358,00€50mg530,00€100mg758,00€200mg1.044,00€CDK9-IN-10
CAS:CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.Fórmula:C22H16O5Pureza:99.8%Cor e Forma:SolidPeso molecular:360.36PCSK9-IN-10
CAS:PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.Fórmula:C18H23N5O4Pureza:99.06%Cor e Forma:SoildPeso molecular:373.41Ref: TM-T72025
2mg39,00€5mg60,00€1mL*10mM (DMSO)62,00€10mg96,00€25mg170,00€50mg266,00€100mg391,00€200mg555,00€CD532
CAS:CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Fórmula:C26H25F3N8OPureza:99.99%Cor e Forma:SolidPeso molecular:522.52CRT-0105950
CAS:CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Fórmula:C21H16ClN3OSPureza:99.78% - 99.86%Cor e Forma:SolidPeso molecular:393.89Ref: TM-T23917
1mg62,00€5mg133,00€1mL*10mM (DMSO)147,00€10mg205,00€25mg416,00€50mg670,00€100mg1.071,00€
