CymitQuimica logo
Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

Exibir 10 mais subcategorias

Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • Fibronectin CS1 Peptide
    Targetmol
    + Info

    Fibronectin CS1 Peptide

    CAS:
    <p>Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.</p>
    Fórmula:C38H64N8O15
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:872.96

    Ref: TM-TP1526

  • Lorutengitide
    Targetmol
    + Info

    Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Fórmula:C30H50N8O12
    Cor e Forma:Solid
    Peso molecular:714.764

    Ref: TM-TP3135

  • GS-443902 trisodium
    Targetmol
    + Info

    GS-443902 trisodium

    CAS:
    <p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>
    Fórmula:C12H16N5O13P3·xNa
    Cor e Forma:Solid

    Ref: TM-T38761

  • Rachelmycin
    Targetmol
    + Info

    Rachelmycin

    CAS:
    <p>Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.</p>
    Fórmula:C37H33N7O8
    Cor e Forma:Solid
    Peso molecular:703.712

    Ref: TM-T40810

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    N6-Methyl-2'-O-(2-methoxyethyl) adenosine

    <p>N6-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Fórmula:C14H21N5O5
    Cor e Forma:Solid
    Peso molecular:339.35

    Ref: TM-T75062

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Mps1-IN-6

    <p>Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].</p>
    Fórmula:C35H39N9O3
    Cor e Forma:Solid
    Peso molecular:633.74

    Ref: TM-T78965

  • Garenoxacin
    Targetmol
    + Info

    Garenoxacin

    CAS:
    <p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>
    Fórmula:C23H20F2N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:426.41

    Ref: TM-T7179

  • Cytidine 5'-diphosphate trisodium salt
    Targetmol
    + Info

    Cytidine 5'-diphosphate trisodium salt

    CAS:
    <p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>
    Fórmula:C9H15N3Na3O11P2
    Pureza:99.55%
    Cor e Forma:White Crystalline Powder
    Peso molecular:472.15

    Ref: TM-T40426

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Anti-EMMPRIN/CD147 Antibody

    <p>Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.</p>
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-803

  • 11H-Benzo[a]carbazole
    Targetmol
    + Info

    11H-Benzo[a]carbazole

    CAS:
    <p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>
    Fórmula:C16H11N
    Pureza:99.14%
    Cor e Forma:Solid
    Peso molecular:217.27

    Ref: TM-TN9686

  • Anticancer agent 263
    Targetmol
    + Info

    Anticancer agent 263

    <p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>
    Fórmula:C13H20N2O6
    Cor e Forma:Solid
    Peso molecular:300.308

    Ref: TM-T204102

  • MYC-IN-2
    Targetmol
    + Info

    MYC-IN-2

    CAS:
    <p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>
    Fórmula:C25H17N3O2S
    Cor e Forma:Solid
    Peso molecular:423.49

    Ref: TM-T39751

  • Cytarabine triphosphate
    Targetmol
    + Info

    Cytarabine triphosphate

    CAS:
    <p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>
    Fórmula:C9H16N3O14P3
    Cor e Forma:Solid
    Peso molecular:483.16

    Ref: TM-T38718

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    5-Aza-xylo-cytidine

    <p>5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>
    Fórmula:C8H12N4O5
    Cor e Forma:Solid
    Peso molecular:244.2

    Ref: TM-T75220

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    KIF2C-IN-1

    <p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>
    Fórmula:C36H39ClN4O9S
    Cor e Forma:Solid
    Peso molecular:738.21263

    Ref: TM-T207280

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Chrexanthomycin C

    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Fórmula:C31H24O15
    Cor e Forma:Solid
    Peso molecular:636.51

    Ref: TM-T75527

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    DHFR-IN-8

    <p>DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.</p>
    Fórmula:C18H14N6S
    Cor e Forma:Solid
    Peso molecular:346.41

    Ref: TM-T79734

  • Xanthosine-5'-Triphosphate
    Targetmol
    + Info

    Xanthosine-5'-Triphosphate

    CAS:
    <p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>
    Fórmula:C10H15N4O15P3
    Cor e Forma:Solid
    Peso molecular:524.164

    Ref: TM-T40714

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    CDK9-IN-25

    <p>CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.</p>
    Fórmula:C15H16FN5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:285.32

    Ref: TM-T79630

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    DSPE-PEG1000-cRGD

    <p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TCL-01160