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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

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  • Ceftriaxone
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    Ceftriaxone

    CAS:
    <p>Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.</p>
    Fórmula:C18H18N8O7S3
    Pureza:96.08%
    Cor e Forma:Solid
    Peso molecular:554.58

    Ref: TM-T75295

  • Logotipo do CymitQuimica
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    Endo-1,4-β-xylanase

    CAS:
    <p>Endo-1,4-β-xylanase (CtXyn11A) is a type of xylan hydrolase that hydrolyzes the β-1,4-glycosidic bond of the xylan molecule.</p>
    Cor e Forma:Solid

    Ref: TM-T76179

  • Logotipo do CymitQuimica
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    N3-[(Pyrid-4-yl)methyl]uridine

    <p>N3-[(Pyrid-4-yl)methyl]uridine, a uridine analog, may have antiepileptic properties and aid in researching anticonvulsants and anxiolytics.</p>
    Fórmula:C15H17N3O6
    Cor e Forma:Solid
    Peso molecular:335.31

    Ref: TM-T75237

  • Cytarabine triphosphate
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    Cytarabine triphosphate

    CAS:
    <p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>
    Fórmula:C9H16N3O14P3
    Cor e Forma:Solid
    Peso molecular:483.16

    Ref: TM-T38718

  • c-Myc inhibitor 7
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    c-Myc inhibitor 7

    CAS:
    <p>c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.</p>
    Fórmula:C35H30N6O5
    Cor e Forma:Soild
    Peso molecular:614.65

    Ref: TM-T72040

  • 5'-O-DMT-PAC-dA
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    5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Fórmula:C39H37N5O7
    Cor e Forma:Solid
    Peso molecular:687.74

    Ref: TM-T37139

  • Logotipo do CymitQuimica
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    3'-Deoxy-GTP trisodium

    <p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, functions as an RNA chain terminator, thereby inhibiting RNA synthesis. It is capable of suppressing dengue virus DENV NS5 RdRp with an IC50 value of 0.02 μM.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T206808

  • CDK4/6-IN-23
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    CDK4/6-IN-23

    <p>CDK4/6-IN-23 (Compound 42) is a potent and selective inhibitor of CDK4/6, displaying an IC50 of 11 nM for CDK6. This compound significantly activates immune cells and enhances IL-3 production. In mice undergoing 5-FU chemotherapy, CDK4/6-IN-23 demonstrates dual bone marrow protection and immunomodulatory effects.</p>
    Fórmula:C32H34FN7O4
    Cor e Forma:Solid
    Peso molecular:599.655

    Ref: TM-T204550

  • Logotipo do CymitQuimica
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    PP-C8

    <p>PP-C8: PROTAC CDK12-Cyclin K degrader with DC50s 416/412 nM; synergizes with PARP inhibitor against TNBC.</p>
    Fórmula:C43H51FN12O7
    Cor e Forma:Solid
    Peso molecular:866.94

    Ref: TM-T74359

  • Gly-Arg-Gly-Asp-Ser
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    Gly-Arg-Gly-Asp-Ser

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>
    Fórmula:C17H30N8O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:490.47

    Ref: TM-TP1459

  • Ficellomycin
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    Ficellomycin

    CAS:
    <p>Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.</p>
    Fórmula:C13H24N6O3
    Cor e Forma:Solid
    Peso molecular:312.37

    Ref: TM-T24063

  • 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine
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    5-O-TBDMS-N4-Benzoyl-2-deoxycytidine

    CAS:
    <p>5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.</p>
    Fórmula:C22H31N3O5Si
    Cor e Forma:Solid
    Peso molecular:445.58

    Ref: TM-T36972

  • Logotipo do CymitQuimica
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    Anti-MRSA agent 7

    <p>Compound 12: a potent anti-MRSA, inhibits S. aureus/E. coli DNA gyrases/topo IV; IC50: 0.185-0.365/0.341-0.059 μM.</p>
    Fórmula:C22H20BrF2N3O4
    Cor e Forma:Solid
    Peso molecular:508.31

    Ref: TM-T74810

  • 5-Methylcytidine 5′-triphosphate
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    5-Methylcytidine 5′-triphosphate

    CAS:
    <p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>
    Fórmula:C10H18N3O14P3
    Cor e Forma:Solid
    Peso molecular:497.18

    Ref: TM-T74584

  • Tirandamycin A
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    Tirandamycin A

    <p>Tirandamycin A is a useful organic compound for research related to life sciences and the catalog number is T124996.</p>
    Fórmula:C22H27NO7
    Cor e Forma:Solid
    Peso molecular:417.458

    Ref: TM-T124996

  • Logotipo do CymitQuimica
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    DG1

    <p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>
    Fórmula:C19H17N5O5S
    Cor e Forma:Solid
    Peso molecular:427.43

    Ref: TM-T78751

  • Logotipo do CymitQuimica
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    Methylcarbamyl PAF C-8

    <p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T206879

  • 5'-O-DMT-N2-DMF-dG
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    5'-O-DMT-N2-DMF-dG

    CAS:
    <p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>
    Fórmula:C34H36N6O6
    Cor e Forma:Solid
    Peso molecular:624.698

    Ref: TM-T40500

  • Barasertib
    Targetmol
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    Barasertib

    CAS:
    <p>AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.</p>
    Fórmula:C26H31FN7O6P
    Pureza:99.63% - 99.92%
    Cor e Forma:Solid
    Peso molecular:587.54

    Ref: TM-T14371

  • CCT241533 dihydrochloride
    Targetmol
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    CCT241533 dihydrochloride

    CAS:
    <p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>
    Fórmula:C23H29Cl2FN4O4
    Cor e Forma:Solid
    Peso molecular:515.41

    Ref: TM-T36704