CymitQuimica logo
Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

Exibir 10 mais subcategorias

Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • Logotipo do CymitQuimica
    Targetmol
    + Info

    FRα-targeting peptide C7 TFA

    <p>FRα-targeting peptide C7 TFA is a selective peptide ligand for the folate receptor alpha (FRα) that specifically binds to FRα-expressing cells and has tumor-targeting capabilities in vivo. It is applicable in research related to tumor diagnosis and therapy.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TP3238

  • CBR-2092
    Targetmol
    + Info

    CBR-2092

    CAS:
    <p>CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor.</p>
    Fórmula:C65H81FN6O15
    Cor e Forma:Solid
    Peso molecular:1205.388

    Ref: TM-T26963

  • SNX7
    Targetmol
    + Info

    SNX7

    CAS:
    <p>SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.</p>
    Fórmula:C15H14N2O
    Pureza:99.05%
    Cor e Forma:Solid
    Peso molecular:238.28

    Ref: TM-T77613

  • LY243246
    Targetmol
    + Info

    LY243246

    CAS:
    <p>LY249543, the S-isomer of lometrexol, is an inhibitor of Methylenetetrahydrofolate Dehydrogenase/Cycl.</p>
    Fórmula:C21H25N5O6
    Cor e Forma:Solid
    Peso molecular:443.45

    Ref: TM-T27933

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    HDAC-IN-85

    <p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>
    Fórmula:C24H27FN4O5
    Cor e Forma:Solid
    Peso molecular:470.49

    Ref: TM-T205411

  • Nusinersen
    Targetmol
    + Info

    Nusinersen

    CAS:
    <p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>
    Pureza:98.62%
    Cor e Forma:Solid

    Ref: TM-T38656

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Catumaxomab

    CAS:
    <p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>
    Pureza:95%
    Cor e Forma:Liquid

    Ref: TM-T78307

  • JAMM protein inhibitor 2 
    Targetmol
    + Info

    JAMM protein inhibitor 2 

    CAS:
    <p>JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.</p>
    Fórmula:C21H26N2O2
    Pureza:98.57%
    Cor e Forma:Solid
    Peso molecular:338.44

    Ref: TM-T9892

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    PROTAC CDK9 degrader-8

    <p>PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].</p>
    Fórmula:C44H52Cl2N10O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:903.85

    Ref: TM-T78928

  • UCK2 Inhibitor-3
    Targetmol
    + Info

    UCK2 Inhibitor-3

    CAS:
    <p>UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.</p>
    Fórmula:C19H13BrFN5O2S
    Cor e Forma:Solid
    Peso molecular:474.31

    Ref: TM-T72696

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Antibacterial agent 144

    <p>Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.</p>
    Fórmula:C26H23N7O3
    Cor e Forma:Solid
    Peso molecular:481.51

    Ref: TM-T79282

  • R-1479
    Targetmol
    + Info

    R-1479

    CAS:
    <p>R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.</p>
    Fórmula:C9H12N6O5
    Pureza:98.11% - 99.95%
    Cor e Forma:Solid
    Peso molecular:284.23

    Ref: TM-TQ0162

  • FF-10502
    Targetmol
    + Info

    FF-10502

    CAS:
    <p>FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.</p>
    Fórmula:C9H12FN3O3S
    Cor e Forma:Solid
    Peso molecular:261.27

    Ref: TM-T39290

  • Guanosine 5'-triphosphate trisodium salt hydrate
    Targetmol
    + Info

    Guanosine 5'-triphosphate trisodium salt hydrate

    CAS:
    <p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>
    Fórmula:C10H18N5NaO15P3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:564.185

    Ref: TM-T10178

  • Ac-MRGDH-NH2
    Targetmol
    + Info

    Ac-MRGDH-NH2

    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Fórmula:C25H41N11O8S
    Cor e Forma:Solid
    Peso molecular:655.727

    Ref: TM-TP3057

  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
    Targetmol
    + Info

    2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    <p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>
    Fórmula:C10H14N5Na2O8P
    Cor e Forma:Solid
    Peso molecular:409.202

    Ref: TM-T35652

  • SMS 121
    Targetmol
    + Info

    SMS 121

    CAS:
    <p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>
    Fórmula:C20H21NO5
    Pureza:98.29%
    Cor e Forma:Soild
    Peso molecular:355.38

    Ref: TM-T205876

  • 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
    Targetmol
    + Info

    6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS:
    <p>6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical and</p>
    Fórmula:C11H15N5O4
    Cor e Forma:Solid
    Peso molecular:281.27

    Ref: TM-T75185

  • RNA splicing modulator 1
    Targetmol
    + Info

    RNA splicing modulator 1

    CAS:
    <p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>
    Fórmula:C19H20N6OS
    Cor e Forma:Solid
    Peso molecular:380.47

    Ref: TM-T74884

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine

    <p>2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effective</p>
    Fórmula:C34H75FN9O12P3
    Cor e Forma:Solid
    Peso molecular:913.93

    Ref: TM-T75207