Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(94 produtos)
- CDK(500 produtos)
- Ciclo celular/Parada(4 produtos)
- Chk(42 produtos)
- DYRK(48 produtos)
- Dinamina(23 produtos)
- Ferroptose(215 produtos)
- HSP(169 produtos)
- Integrinas(224 produtos)
- Cinesina(66 produtos)
- LIM Quinase(19 produtos)
- Microtúbulo associado(261 produtos)
- PKC(102 produtos)
- PLK(28 produtos)
- ROCK(70 produtos)
- Rho(2 produtos)
- Wee1(15 produtos)
- c-Myc(69 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PD-1/PD-L1-IN-51
<p>PD-1/PD-L1-IN-51 (Compound III-4) is an inhibitor of PD-1/PD-L1 (IC50: hPD-L1 at 2.9 nM). It binds directly to PD-L1, blocking the interaction between PD-1 and PD-L1, and enhancing the release of IFN-γ. Additionally, PD-1/PD-L1-IN-51 exhibits antitumor activity.</p>Cor e Forma:Odour SolidLB80317
CAS:<p>LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.</p>Fórmula:C10H14N5O5PCor e Forma:SolidPeso molecular:315.22Ceftriaxone
CAS:<p>Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.</p>Fórmula:C18H18N8O7S3Pureza:96.08%Cor e Forma:SolidPeso molecular:554.585'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine
<p>5’-O-Benzoyl-3’-O-(4-methoxybenzyl)-2’-O,4’-C-methyleneuridine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolent</p>Fórmula:C25H24N2O8Cor e Forma:SolidPeso molecular:480.47Orbofiban acetate
CAS:<p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>Fórmula:C19H27N5O6Cor e Forma:SolidPeso molecular:421.452'-OMe-Ac-C Phosphoramidite
CAS:<p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>Fórmula:C42H52N5O9PCor e Forma:SolidPeso molecular:801.86LXY3
CAS:<p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>Fórmula:C32H43N11O15S2Cor e Forma:SolidPeso molecular:885.88CCT241533 dihydrochloride
CAS:<p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>Fórmula:C23H29Cl2FN4O4Cor e Forma:SolidPeso molecular:515.41m7GpppGpG
CAS:<p>m7GpppGpG, a trinucleotide cap, protects mRNA from 5′ exonucleases & aids splicing and translation.</p>Fórmula:C31H41N15O25P4Cor e Forma:SolidPeso molecular:1147.642'-O-Methyladenosine 5'-monophosphate triethyl ammonium
<p>2’-O-Methyladenosine 5’-monophosphate triethyl ammonium is an adenosine analog.</p>Fórmula:C11H14N5O7P2Cor e Forma:SolidPeso molecular:359.23Ribonuclease T1
CAS:<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Cor e Forma:SolidGS-443902 trisodium
CAS:<p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>Fórmula:C12H16N5O13P3·xNaCor e Forma:SolidDNA Gyrase-IN-12
<p>DNA Gyrase-IN-12 (Compound 6d) is an inhibitor of DNA gyrase. It exhibits antibacterial activity with MIC values ranging from 0.031 to 0.0625 μg/mL against Vancomycin-Intermediate Staphylococcus aureus (VISA) and Enterococcus faecium.</p>Cor e Forma:Odour SolidCDK7-IN-2 hydrochloride hydrate
CAS:<p>CDK7-IN-2 HCl hydrate is a potent, specific CDK7 enzyme inhibitor with significant anti-cancer effects.</p>Fórmula:C26H42ClN7O4Cor e Forma:SolidPeso molecular:552.12Apcin A HCL
CAS:<p>Apcin A HCL is an Apcin-derived APC inhibitor that binds Cdc20 and hinders ubiquitination, useful for synthesizing PROTAC CP5V.</p>Fórmula:C10H15Cl4N5O2Pureza:99.59%Cor e Forma:SolidPeso molecular:379.07N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine
<p>N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoid</p>Fórmula:C16H16FN3O5Cor e Forma:SolidPeso molecular:349.318-Chloro-2'-deoxy-2'-fluoro-arabino adenosine
<p>8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine, a purine nucleoside analog, demonstrates broad antitumor activity against indolent lymphoid malignancies.</p>Fórmula:C10H11ClFN5O3Cor e Forma:SolidPeso molecular:303.68TFMU-ADPr triethylamine
<p>TFMU-ADPr triethylamine is a substrate for PARG activity measurement, releasing a fluorophore to indicate PAR hydrolase activity.</p>Fórmula:C25H26F3N5O16P2·5C6H15NCor e Forma:SolidPeso molecular:1024.42IRE1-IN-2
<p>IRE1-IN-2 (compound G15) functions as a potent inhibitor of IRE1. It effectively suppresses lipid accumulation induced by FFA, exhibiting an IC50 value of 2.06 μM.</p>Fórmula:C16H20O6Cor e Forma:SolidPeso molecular:308.12599huATN-658
<p>huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting the urokinase-type plasminogen activator receptor (uPAR). It effectively disrupts the interaction between uPAR and integrins, thereby inhibiting tumor cell proliferation, invasion, and migration. huATN-658 shows potential for research in breast cancer, particularly in cases of triple-negative breast cancer.</p>Cor e Forma:Odour Liquid
