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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

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  • 5'-O-DMT-PAC-dA
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    5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Fórmula:C39H37N5O7
    Cor e Forma:Solid
    Peso molecular:687.74

    Ref: TM-T37139

  • LDV FITC
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    LDV FITC

    CAS:
    <p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>
    Fórmula:C69H81N11O17S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1368.53

    Ref: TM-T23568

  • Erythromycin A dihydrate
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    Erythromycin A dihydrate

    CAS:
    <p>Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.</p>
    Fórmula:C37H69NO14
    Cor e Forma:Solid
    Peso molecular:751.94

    Ref: TM-T40676

  • AV-153
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    AV-153

    CAS:
    <p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>
    Fórmula:C14H19NNaO6
    Cor e Forma:Solid
    Peso molecular:320.297

    Ref: TM-T40345

  • 8-NH2-ATP
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    8-NH2-ATP

    CAS:
    <p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>
    Fórmula:C10H17N6O13P3
    Cor e Forma:Solid
    Peso molecular:522.20

    Ref: TM-T40455

  • Logotipo do CymitQuimica
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    5-Caroxy uracil-1-yl acetic acid benzyl ester

    <p>5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>
    Fórmula:C14H12N2O6
    Cor e Forma:Solid
    Peso molecular:304.25

    Ref: TM-T75189

  • Isocytosine
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    Isocytosine

    CAS:
    <p>Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Fórmula:C4H5N3O
    Cor e Forma:White To Off-White Solid
    Peso molecular:111.1

    Ref: TM-PDK0016

  • IV-361
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    IV-361

    CAS:
    <p>IV-361, an orally active and selective CDK7 inhibitor with a Ki value of less than or equal to 50 nM, demonstrates potent anti-cancer activity (US20190256531A1</p>
    Fórmula:C23H32FN5O2Si
    Cor e Forma:Solid
    Peso molecular:457.625

    Ref: TM-T39456

  • Logotipo do CymitQuimica
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    Rev 2'-O-MOE-C(Bz)-5'-amidite

    <p>'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>
    Fórmula:C49H58N5O10P
    Cor e Forma:Solid
    Peso molecular:907.99

    Ref: TM-T75206

  • Logotipo do CymitQuimica
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    Dafsolimab

    CAS:
    <p>Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is</p>
    Cor e Forma:Liquid

    Ref: TM-T80597

  • SR15006
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    SR15006

    CAS:
    <p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>
    Fórmula:C16H20ClN3O4S
    Pureza:99.87%
    Cor e Forma:Soild
    Peso molecular:385.87

    Ref: TM-T60037

  • Nogalamycin
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    Nogalamycin

    CAS:
    <p>Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.</p>
    Fórmula:C39H49NO16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:787.812

    Ref: TM-T28185

  • Logotipo do CymitQuimica
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    Chrexanthomycin C

    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Fórmula:C31H24O15
    Cor e Forma:Solid
    Peso molecular:636.51

    Ref: TM-T75527

  • Ac-MRGDH-NH2
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    Ac-MRGDH-NH2

    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Fórmula:C25H41N11O8S
    Cor e Forma:Solid
    Peso molecular:655.727

    Ref: TM-TP3057

  • Logotipo do CymitQuimica
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    DHFR-IN-8

    <p>DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.</p>
    Fórmula:C18H14N6S
    Cor e Forma:Solid
    Peso molecular:346.41

    Ref: TM-T79734

  • Logotipo do CymitQuimica
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    N1-Methylpseudouridine-5′-triphosphate tetralithium

    <p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>
    Fórmula:C10H13Li4N2O15P3
    Cor e Forma:Solid
    Peso molecular:521.9

    Ref: TM-T73736

  • GRGDSP
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    GRGDSP

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>
    Fórmula:C22H37N9O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:587.58

    Ref: TM-TP1421

  • Logotipo do CymitQuimica
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    3'-β-C-Methyl-N6-isopentenyl adenosine

    <p>3’-Beta-C-Methyl-N6-isopentenyl adenosine is an adenosine analog.</p>
    Fórmula:C16H23N5O4
    Cor e Forma:Solid
    Peso molecular:349.38

    Ref: TM-T75046

  • Logotipo do CymitQuimica
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    Brr2-IN-2

    <p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>
    Fórmula:C21H25FN4O2
    Cor e Forma:Solid
    Peso molecular:384.45

    Ref: TM-T205260

  • Logotipo do CymitQuimica
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    3'-Deoxy-GTP trisodium

    <p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, functions as an RNA chain terminator, thereby inhibiting RNA synthesis. It is capable of suppressing dengue virus DENV NS5 RdRp with an IC50 value of 0.02 μM.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T206808