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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

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  • Orbofiban acetate
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    Orbofiban acetate

    CAS:
    <p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>
    Fórmula:C19H27N5O6
    Cor e Forma:Solid
    Peso molecular:421.45

    Ref: TM-T73643

  • 2'-OMe-Ac-C Phosphoramidite
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    2'-OMe-Ac-C Phosphoramidite

    CAS:
    <p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>
    Fórmula:C42H52N5O9P
    Cor e Forma:Solid
    Peso molecular:801.86

    Ref: TM-T75265

  • JH-XVI-178
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    JH-XVI-178

    CAS:
    <p>JH-XVI-178: potent CDK8/19 inhibitor with good pharmacokinetics, low clearance, moderate oral bioavailability.</p>
    Fórmula:C22H22ClN7O
    Cor e Forma:Solid
    Peso molecular:435.92

    Ref: TM-T40280

  • T-2513
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    T-2513

    CAS:
    <p>T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.</p>
    Fórmula:C25H27N3O5
    Cor e Forma:Solid
    Peso molecular:449.507

    Ref: TM-T40365

  • 5'-O-DMT-rI
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    5'-O-DMT-rI

    CAS:
    <p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>
    Fórmula:C31H30N4O7
    Cor e Forma:Solid
    Peso molecular:570.59

    Ref: TM-T37140

  • Logotipo do CymitQuimica
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    6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    <p>6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, boasts a broad spectrum of biochemical and</p>
    Fórmula:C10H17N7O3
    Cor e Forma:Solid
    Peso molecular:283.29

    Ref: TM-T75187

  • Logotipo do CymitQuimica
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    STX-100

    <p>PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.</p>
    Pureza:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-062

  • Py-MAA-Val-Cit-PAB-DX8951
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    Py-MAA-Val-Cit-PAB-DX8951

    CAS:
    <p>Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].</p>
    Fórmula:C57H66FN11O13S
    Cor e Forma:Solid
    Peso molecular:1164.26

    Ref: TM-T75117

  • Logotipo do CymitQuimica
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    PP-C8

    <p>PP-C8: PROTAC CDK12-Cyclin K degrader with DC50s 416/412 nM; synergizes with PARP inhibitor against TNBC.</p>
    Fórmula:C43H51FN12O7
    Cor e Forma:Solid
    Peso molecular:866.94

    Ref: TM-T74359

  • Logotipo do CymitQuimica
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    1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine

    <p>1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine is an adenosine analog.</p>
    Fórmula:C18H18F3N5O4
    Cor e Forma:Solid
    Peso molecular:425.36

    Ref: TM-T75042

  • CDK12-IN-6
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    CDK12-IN-6

    CAS:
    <p>CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 &gt;20 μM).</p>
    Fórmula:C20H21F2N9
    Cor e Forma:Solid
    Peso molecular:425.448

    Ref: TM-T40289

  • LXY3
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    LXY3

    CAS:
    <p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>
    Fórmula:C32H43N11O15S2
    Cor e Forma:Solid
    Peso molecular:885.88

    Ref: TM-TP3270

  • Heliquinomycin
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    Heliquinomycin

    CAS:
    <p>Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.</p>
    Fórmula:C33H30O17
    Cor e Forma:Solid
    Peso molecular:698.586

    Ref: TM-T36748

  • Logotipo do CymitQuimica
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    5'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite

    <p>5’-O-DMTr-2’-O-MOE inosine 3’-P-methyl phosphonamidite, a purine nucleoside analog, exhibits extensive antitumor activity specific to indolent lymphoid</p>
    Fórmula:C41H52N5O8P
    Cor e Forma:Solid
    Peso molecular:773.85

    Ref: TM-T75229

  • (1S,3R,5R)-PIM447 dihydrochloride
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    (1S,3R,5R)-PIM447 dihydrochloride

    <p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>
    Fórmula:C24H25Cl2F3N4O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:513.38

    Ref: TM-T13425

  • Logotipo do CymitQuimica
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    Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester

    <p>Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.</p>
    Fórmula:C24H24N2O9
    Cor e Forma:Solid
    Peso molecular:484.46

    Ref: TM-T75087

  • Logotipo do CymitQuimica
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    N1-Methyl-2'-O-(2-methoxyethyl) guanosine

    <p>N1-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>
    Fórmula:C14H21N5O6
    Cor e Forma:Solid
    Peso molecular:355.35

    Ref: TM-T75059

  • Anticancer agent 84
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    Anticancer agent 84

    CAS:
    <p>Anticancer agent 84 inhibits c-MYC transcription by stabilizing G4 structures, aiding cancer research.</p>
    Fórmula:C57H67N7O9
    Cor e Forma:Solid
    Peso molecular:994.18

    Ref: TM-T74961

  • 5-Iminodaunorubicin
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    5-Iminodaunorubicin

    CAS:
    <p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>
    Fórmula:C27H30N2O9
    Cor e Forma:Solid
    Peso molecular:526.54

    Ref: TM-T72467

  • 6-Thioguanosine
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    6-Thioguanosine

    CAS:
    <p>6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.</p>
    Fórmula:C10H13N5O4S
    Pureza:97.05%
    Cor e Forma:Yellow-Green Powder
    Peso molecular:299.31

    Ref: TM-T20511