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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

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  • Isocytosine
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    Isocytosine

    CAS:
    <p>Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Fórmula:C4H5N3O
    Cor e Forma:White To Off-White Solid
    Peso molecular:111.1

    Ref: TM-PDK0016

  • Ac-MRGDH-NH2
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    Ac-MRGDH-NH2

    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Fórmula:C25H41N11O8S
    Cor e Forma:Solid
    Peso molecular:655.727

    Ref: TM-TP3057

  • Ac-dA Phosphoramidite
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    Ac-dA Phosphoramidite

    CAS:
    <p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Fórmula:C42H50N7O7P
    Cor e Forma:Solid
    Peso molecular:795.878

    Ref: TM-T38425

  • CDK6/9-IN-1
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    CDK6/9-IN-1

    CAS:
    <p>CDK6/9-IN-1, an oral dual inhibitor of CDK6/9, has IC50s of 40.5nM (CDK6) and 39.5nM (CDK9).</p>
    Fórmula:C22H25ClN8O
    Cor e Forma:Solid
    Peso molecular:452.95

    Ref: TM-T40047

  • 5'-O-DMT-ibu-dC
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    5'-O-DMT-ibu-dC

    CAS:
    <p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>
    Fórmula:C34H37N3O7
    Cor e Forma:Solid
    Peso molecular:599.67

    Ref: TM-T38405

  • Logotipo do CymitQuimica
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    5-Methylcytidine 5′-triphosphate trisodium

    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Fórmula:C10H15N3Na3O14P3
    Cor e Forma:Solid
    Peso molecular:563.13

    Ref: TM-T74585

  • Logotipo do CymitQuimica
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    Obtustatin

    <p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>
    Fórmula:C184H284N52O57S8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4393.07

    Ref: TM-TP1974

  • Logotipo do CymitQuimica
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    UnyLinker 12 TEA

    <p>UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.</p>
    Fórmula:C39H35NO10C6H15N
    Cor e Forma:Solid
    Peso molecular:778.34655

    Ref: TM-TSW-00947

  • WAY-647802
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    WAY-647802

    CAS:
    <p>WAY-647802 is a CDK inhibitor.</p>
    Fórmula:C11H14N4O3
    Pureza:99.53%
    Cor e Forma:Solid
    Peso molecular:250.25

    Ref: TM-T9971

  • 3'-Deoxyuridine-5'-triphosphate trisodium
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    3'-Deoxyuridine-5'-triphosphate trisodium

    <p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>
    Fórmula:C9H12N2Na3O14P3
    Cor e Forma:Soild
    Peso molecular:534.08

    Ref: TM-T35658

  • 5'-O-DMT-N4-Bz-2'-F-dC
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    5'-O-DMT-N4-Bz-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>
    Fórmula:C37H34FN3O7
    Cor e Forma:Solid
    Peso molecular:651.68

    Ref: TM-T37137

  • α2β1 Integrin Ligand Peptide
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    α2β1 Integrin Ligand Peptide

    CAS:
    <p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>
    Fórmula:C14H22N4O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:390.35

    Ref: TM-TP1484

  • Logotipo do CymitQuimica
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    N7-Methyl-2'-O-(2-methoxyethyl) guanosine

    <p>N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Fórmula:C14H21N5O6
    Cor e Forma:Solid
    Peso molecular:355.35

    Ref: TM-T75060

  • Pseudouridimycin
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    Pseudouridimycin

    CAS:
    <p>Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.</p>
    Fórmula:C17H26N8O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:486.44

    Ref: TM-T16673

  • Logotipo do CymitQuimica
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    TC113

    <p>TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.</p>
    Fórmula:C37H50F2N12O13
    Cor e Forma:Solid
    Peso molecular:908.86

    Ref: TM-T74400

  • Anticancer agent 263
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    Anticancer agent 263

    <p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>
    Fórmula:C13H20N2O6
    Cor e Forma:Solid
    Peso molecular:300.308

    Ref: TM-T204102

  • CDK7-IN-5
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    CDK7-IN-5

    CAS:
    <p>CDK7-IN-5, a CDK7 inhibitor with an IC 50 value of less than 100 nM, exhibits potent anticancer properties (WO2015154022A1, Compound 104).</p>
    Fórmula:C34H45N9O2
    Cor e Forma:Solid
    Peso molecular:611.795

    Ref: TM-T39247

  • PROTAC CDK9 degrader-2
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    PROTAC CDK9 degrader-2

    CAS:
    <p>PROTAC CDK9 degrader-2, potent, selective, IC50 17 μM in MCF-7, wogonin-derived, targets CRBN.</p>
    Fórmula:C39H36N6O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:748.74

    Ref: TM-T17728

  • Barasertib
    Targetmol
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    Barasertib

    CAS:
    <p>AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.</p>
    Fórmula:C26H31FN7O6P
    Pureza:99.63% - 99.92%
    Cor e Forma:Solid
    Peso molecular:587.54

    Ref: TM-T14371

  • Logotipo do CymitQuimica
    Targetmol
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    GK13S

    <p>G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.</p>
    Fórmula:C21H22N6O2
    Cor e Forma:Solid
    Peso molecular:390.44

    Ref: TM-T75182