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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

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Foram encontrados 3486 produtos de "Ciclo celular/Ponto de verificação"

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produtos por página.
  • Antiangiogenic agent 2


    <p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>
    Fórmula:C26H26FN3O4
    Cor e Forma:Solid
    Peso molecular:463.5
  • Dyrk1A-IN-8

    CAS:
    <p>Dyrk1A-IN-8 is an active molecule that can be used in life science related research. The CAS number of Dyrk1A-IN-8 is 101578-13-6.</p>
    Fórmula:C17H21N3O
    Cor e Forma:Solid
    Peso molecular:283.37
  • 2'-(2-Nitrobenzyl)-ATP

    CAS:
    <p>2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.</p>
    Fórmula:C17H21N6O15P3
    Cor e Forma:Solid
    Peso molecular:642.30
  • Ladirubicin

    CAS:
    <p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>
    Fórmula:C29H31NO11S
    Cor e Forma:Solid
    Peso molecular:601.62
  • CHK1-IN-11

    CAS:
    <p>CHK1-IN-11 (Compound 1) is an orally active inhibitor of checkpoint kinase 1 (CHK1). It is utilized in research focused on cancers with oncogene amplification.</p>
    Fórmula:C20H22N8O2
    Cor e Forma:Solid
    Peso molecular:406.44
  • CDK9-IN-11

    CAS:
    <p>CDK9-IN-11 is a potent CDK9 inhibitor that is the ligand for the PROTAC CDK9 Degrader-1 [1].</p>
    Fórmula:C20H25N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:371.43
  • MtTMPK-IN-8


    <p>MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.</p>
    Fórmula:C24H24N6O7
    Cor e Forma:Solid
    Peso molecular:508.48
  • CDK4/6-IN-3

    CAS:
    <p>CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: &lt;0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.</p>
    Fórmula:C25H31FN8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:462.57
  • CD 10899

    CAS:
    <p>CD 10899, a hydroxylated metabolite of Volasertib, is pharmacologically active against Polo-like kinase 1 (PLK1) with an IC50 of 6 nM. Volasertib is an orally active, highly potent, and ATP-competitive PLK1 inhibitor. CD 10899 can be used for cancer research [1].</p>
    Fórmula:C34H50N8O4
    Cor e Forma:Solid
    Peso molecular:634.81
  • iPAF1C

    CAS:
    <p>iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].</p>
    Fórmula:C27H26BrFN4O
    Cor e Forma:Solid
    Peso molecular:521.42
  • DHX9-IN-19

    CAS:
    <p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>
    Fórmula:C20H21ClN4O4S2
    Cor e Forma:Solid
    Peso molecular:480.988
  • DNA polymerase-IN-6

    CAS:
    <p>DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.</p>
    Fórmula:C26H28ClFN8O4
    Cor e Forma:Solid
    Peso molecular:571.003
  • Mps1-IN-8

    CAS:
    <p>Mps1-IN-8, a Mps1 inhibitor, can be utilized in the study of various tumors [1].</p>
    Fórmula:C35H47N8O6P
    Cor e Forma:Solid
    Peso molecular:706.77
  • LIMK-IN-2

    CAS:
    <p>LIMK-IN-2 (Compound 52), an LIMK inhibitor, has demonstrated potential anti-angiogenic activity by suppressing the cell migration of osteosarcoma and cervical cancer cells [1].</p>
    Fórmula:C28H27N5O2
    Cor e Forma:Solid
    Peso molecular:465.55
  • LIMK1 inhibitor 1

    CAS:
    <p>LIMK1 inhibitor1 (compound 24) is a LIMK1 inhibitor, potentially useful for cancer research.</p>
    Fórmula:C12H15N3S2
    Cor e Forma:Solid
    Peso molecular:265.398
  • PLK1-IN-11

    CAS:
    <p>PLK1-IN-11 (Cluster 4, 16953209) is a PLK1 inhibitor with an IC50 of 1 μM. It is applicable in research on various cancers such as pancreatic, ovarian, breast, and non-small cell lung cancer.</p>
    Fórmula:C12H11N5O
    Cor e Forma:Solid
    Peso molecular:241.249
  • DNA Gyrase-IN-13

    CAS:
    <p>DNA Gyrase-IN-13 (compound 1b) is an inhibitor of DNA gyrase with bacteriostatic properties. It exhibits an IC50 of 1.81 μM against Staphylococcus aureus DNA gyrase.</p>
    Fórmula:C15H21N3O3S
    Cor e Forma:Solid
    Peso molecular:323.41
  • LNA-CTP

    CAS:
    <p>LNA-CTP is a nucleotide analog utilized in the synthesis of oligonucleotides.</p>
    Fórmula:C10H16N3O14P3
    Cor e Forma:Solid
    Peso molecular:495.17
  • Lobucavir

    CAS:
    <p>Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).</p>
    Fórmula:C11H15N5O3
    Cor e Forma:Solid
    Peso molecular:265.27
  • WRN inhibitor 11

    CAS:
    <p>WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.</p>
    Fórmula:C34H35ClF3N9O5
    Cor e Forma:Solid
    Peso molecular:742.15
  • WRN inhibitor 12

    CAS:
    WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.
    Fórmula:C33H33ClF3N9O5
    Cor e Forma:Solid
    Peso molecular:728.12
  • Xanthosine-5'-Triphosphate trisodium

    CAS:
    <p>Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).</p>
    Fórmula:C10H12N4Na3O15P3
    Cor e Forma:Solid
    Peso molecular:590.111
  • WEE1-IN-11

    CAS:
    WEE1-IN-11 (Compound 13) serves as a potent CDK2 inhibitor with an IC50 of 2.0 nM. It exhibits inhibitory effects on several cell lines, including NCI-H446, A427, OVCAR3, C33A, and WiDr, with respective IC50 values of 93.9, 34.5, 86.7, 23.1, and 85 nM.
    Fórmula:C26H29FN8OS2
    Cor e Forma:Solid
    Peso molecular:552.69
  • CDK2-IN-31

    CAS:
    <p>CDK2-IN-31 (compound I-125A) is an inhibitor of CDK2 and is utilized in cancer research.</p>
    Fórmula:C37H52N6O5
    Cor e Forma:Solid
    Peso molecular:660.85
  • Dyrk1A-IN-4

    CAS:
    <p>Dyrk1A-IN-4, compound 48, is an oral DYRK1A/DYRK2 inhibitor with IC50s: 2 nM (DYRK1A), 6 nM (DYRK2), anticancer properties.</p>
    Fórmula:C14H13F3N6
    Cor e Forma:Solid
    Peso molecular:322.29
  • BWC0977

    CAS:
    <p>BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.</p>
    Fórmula:C22H21FN6O5
    Cor e Forma:Solid
    Peso molecular:468.44
  • SGC-CLK-1

    CAS:
    <p>SGC-CLK-1 is a potent and selective inhibitor of Cdc2-like kinases CLK1, CLK2, and CLK4. It effectively inhibits the growth of melanoma and glioblastoma cells.</p>
    Fórmula:C19H15F3N6O2
    Cor e Forma:Solid
    Peso molecular:416.36
  • Polθ-IN-6

    CAS:
    <p>Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.</p>
    Fórmula:C25H23N3O3S
    Cor e Forma:Solid
    Peso molecular:445.53
  • Polθ-IN-5

    CAS:
    <p>Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.</p>
    Fórmula:C23H18ClF2N7O3S
    Cor e Forma:Solid
    Peso molecular:545.95
  • CDK12/13 ligand 1

    CAS:
    <p>ALK-IN-29 (compound 4c) exhibits notable inhibitory activity against tyrosine kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, showing a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is useful for cancer research.</p>
    Fórmula:C26H26BrN5O
    Cor e Forma:Solid
    Peso molecular:504.42
  • Bersiporocin

    CAS:
    <p>Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.</p>
    Fórmula:C15H19Cl2N3O
    Pureza:98.88% - 99.79%
    Cor e Forma:Solid
    Peso molecular:328.24
  • 2′-F-UDP

    CAS:
    <p>2′-F-UDP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C9H13FN2O11P2
    Cor e Forma:Solid
    Peso molecular:406.15
  • CYP2C19-IN-1


    <p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>
    Fórmula:C26H26N2O6S
    Cor e Forma:Solid
    Peso molecular:494.56
  • Polθ-IN-7

    CAS:
    <p>Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.</p>
    Fórmula:C28H35F3N6O2
    Cor e Forma:Solid
    Peso molecular:544.612
  • 12(S)-HETE

    CAS:
    <p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>
    Fórmula:C20H32O3
    Cor e Forma:Solid
    Peso molecular:320.47
  • Methyl 3-oxodecanoate

    CAS:
    <p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>
    Fórmula:C11H20O3
    Cor e Forma:Solid
    Peso molecular:200.275
  • CDK2-IN-30

    CAS:
    <p>CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.</p>
    Fórmula:C18H25N7O3S
    Cor e Forma:Solid
    Peso molecular:419.50
  • PD-1/PD-L1-IN-53

    CAS:
    <p>PD-1/PD-L1-IN-53 (compound B3) serves as an inhibitor targeting both the PD-1/PD-L1 and VISTA signaling pathways. It is utilized in cancer research.</p>
    Fórmula:C31H37N3O4
    Cor e Forma:Solid
    Peso molecular:515.64
  • PD-L1-IN-7

    CAS:
    <p>PD-L1-IN-7 (compound CB31) serves as a PD-L1 inhibitor, effectuating PD-L1 internalization and retention within cells. It restrains the PD-1/PD-L1 interaction (IC 50: 0.2 nM), alters glycosylation patterns, and facilitates PD-L1 degradation. Additionally, PD-L1-IN-7 enhances T cell infiltration, boosts T cell function, and augments the capacity to destroy tumor cells.</p>
    Fórmula:C46H50N6O7
    Cor e Forma:Solid
    Peso molecular:798.93
  • WEE1-IN-10

    CAS:
    <p>WEE1-IN-10 is a Wee1 kinase inhibitor that inhibits the growth of LOVO cells, such as pancreatic cancer, malignant melanoma, and malignant glioma.</p>
    Fórmula:C28H30Cl2N8O
    Pureza:98.18%
    Cor e Forma:Solid
    Peso molecular:565.5
  • GTSE1-IN-1

    CAS:
    <p>GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.</p>
    Fórmula:C21H24FN7
    Cor e Forma:Solid
    Peso molecular:393.46
  • CDK1-IN-3


    <p>CDK1-IN-3 is a selective inhibitor targeting CDK1 (36.8 nM), CDK2 (305.17 nM), CDK5 (369.37 nM); used in cancer research.</p>
    Fórmula:C28H25ClF3N5O2
    Cor e Forma:Solid
    Peso molecular:555.98
  • Z4P

    CAS:
    <p>Z4P, an IRE1 inhibitor with blood-brain barrier permeability (BBB), inhibited glioblastoma growth and recurrence in combination with Temozolomide.</p>
    Fórmula:C19H24N2O2
    Pureza:98.99%
    Cor e Forma:Solid
    Peso molecular:312.41
  • DDO-6079

    CAS:
    <p>DDO-6079 is an efficient CDC37 inhibitor. It suppresses the HSP90-CDC37 and CDC37-CDK4/6 chaperone complexes by binding to an allosteric site on CDC37. Additionally, DDO-6079 reduces the thermal stability of CDK6.</p>
    Fórmula:C18H13ClN2O3
    Cor e Forma:Solid
    Peso molecular:340.76
  • TY-011

    CAS:
    <p>TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 μM. It is utilized in research focused on gastric cancer.</p>
    Fórmula:C18H16ClN5
    Cor e Forma:Solid
    Peso molecular:337.81
  • 3'-Deoxy-GTP

    CAS:
    <p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) is an analog of GTP and serves as an RNA chain terminator, effectively inhibiting RNA synthesis. It can inhibit dengue virus DENV NS5 RdRp with an IC50 of 0.02 μM.</p>
    Fórmula:C10H16N5O13P3
    Cor e Forma:Solid
    Peso molecular:507.181
  • 2-CEES

    CAS:
    <p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>
    Fórmula:C4H9ClS
    Cor e Forma:Solid
    Peso molecular:124.632
  • APE1-IN-3

    CAS:
    <p>APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.</p>
    Fórmula:C17H16O4
    Cor e Forma:Solid
    Peso molecular:284.31
  • CHK-IN-1

    CAS:
    <p>CHK-IN-1 is a dual inhibitor of CHK1 and CHK2 with antiproliferative activity.</p>
    Fórmula:C18H19ClFN5OS
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:407.89
  • WRN inhibitor 13

    CAS:
    <p>WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.</p>
    Fórmula:C16H20N2O5S
    Cor e Forma:Solid
    Peso molecular:352.405
  • PCNA-IN-1

    CAS:
    <p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>
    Fórmula:C19H18I3NO3
    Cor e Forma:Solid
    Peso molecular:689.065
  • WEE1/PKMYT1-IN-1

    CAS:
    <p>WEE1/PKMYT1-IN-1 (compound 75) is an effective and orally bioavailable inhibitor of WEE1 and PKMYT1. It demonstrates antiproliferative activity.</p>
    Fórmula:C16H16N4O3
    Cor e Forma:Solid
    Peso molecular:312.323
  • LNA-AMP

    CAS:
    <p>LNA-AMP is a nucleotide analog used in the synthesis of oligonucleotides.</p>
    Fórmula:C11H14N5O7P
    Cor e Forma:Solid
    Peso molecular:359.23
  • CDK8-IN-9


    <p>CDK8-IN-9, potent CDK8 inhibitor (IC50: 48.6 nM), curbs tumor growth, useful for colorectal cancer research.</p>
    Cor e Forma:Solid
  • TASIN-30

    CAS:
    <p>TASIN-30 is an inhibitor of EBP, exhibiting a competitive EC50 value of 0.097 μM, and possesses a competitive EC50 value of 50 μM against DHCR7.</p>
    Fórmula:C18H30N2O3S
    Cor e Forma:Solid
    Peso molecular:354.51
  • Antiviral agent 67

    CAS:
    <p>Antiviralagent 67 (compound PC6) is an inhibitor of DENVNS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM.</p>
    Fórmula:C19H19N3O
    Cor e Forma:Solid
    Peso molecular:305.374
  • 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine

    CAS:
    <p>5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside synthesized through oxime ring-opening at the 5' position and methylation at the 2' position. In chemotaxis assays, 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine demonstrates tissue affinity.</p>
    Fórmula:C36H39N5O8
    Cor e Forma:Solid
    Peso molecular:669.724
  • GSK_WRN4

    CAS:
    <p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>
    Fórmula:C16H20N2O4S
    Pureza:99.95%
    Cor e Forma:Solid
    Peso molecular:336.41
  • Cimpuciclib tosylate

    CAS:
    <p>Cimpuciclib tosylate, a selective CDK4 inhibitor (IC50: 0.49 nM), exhibits anti-tumor activity.</p>
    Fórmula:C37H43FN8O4S
    Cor e Forma:Solid
    Peso molecular:714.85
  • GFB-12811

    CAS:
    <p>GFB-12811 is an orally active, selective, and potent CDK5 inhibitor, used in the study of autosomal dominant polycystic kidney disease.</p>
    Fórmula:C22H23F4N5O
    Pureza:98.88%
    Cor e Forma:Solid
    Peso molecular:449.44
  • HRO761

    CAS:
    <p>HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.</p>
    Fórmula:C31H31ClF3N9O5
    Pureza:98.74% - 99.62%
    Cor e Forma:Solid
    Peso molecular:702.08
  • Elacytarabine

    CAS:
    <p>Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.</p>
    Fórmula:C27H45N3O6
    Pureza:97.69%
    Cor e Forma:Solid
    Peso molecular:507.66
  • CTPS1-IN-1

    CAS:
    <p>CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.</p>
    Fórmula:C21H22N6O4S2
    Pureza:99.46%
    Cor e Forma:Solid
    Peso molecular:486.57
  • LY3143921 hydrate

    CAS:
    <p>LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].</p>
    Fórmula:C16H14FN5O2
    Pureza:98.43%
    Cor e Forma:Solid
    Peso molecular:327.31
  • SR 11302

    CAS:
    <p>SR 11302 is an inhibitor of activator protein-1 (AP-1).</p>
    Fórmula:C26H32O2
    Pureza:98.65%
    Cor e Forma:Solid
    Peso molecular:376.53
  • INCB086550

    CAS:
    <p>INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 &lt;= 10 nM.</p>
    Fórmula:C41H39N7O4
    Pureza:98.49%
    Cor e Forma:Solid
    Peso molecular:693.79
  • Troxacitabine

    CAS:
    <p>Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious against Panc-01.</p>
    Fórmula:C8H11N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:213.19

    Ref: TM-T17175

    1mg
    Descontinuado
    Produto descontinuado
  • Bicyclomycin benzoate

    CAS:
    <p>Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.</p>
    Fórmula:C19H22N2O8
    Cor e Forma:Solid
    Peso molecular:406.39

    Ref: TM-T10541

    1mg
    Descontinuado
    Produto descontinuado
  • Deoxypseudouridine

    CAS:
    <p>Deoxypseudouridine is a nucleotide analog.</p>
    Fórmula:C9H12N2O5
    Cor e Forma:Solid
    Peso molecular:228.2

    Ref: TM-T13645

    1mg
    Descontinuado
    1ml*10 (DMSO)
    Descontinuado
    Produto descontinuado
  • PLK1-IN-6


    <p>PLK1-IN-6: potent, selective PLK1 inhibitor, IC50 = 0.45 nM, hinders cancer cell growth.</p>
    Fórmula:C28H37N9O3
    Cor e Forma:Solid
    Peso molecular:547.65

    Ref: TM-T74777

    5mg
    Descontinuado
    50mg
    Descontinuado
    Produto descontinuado
  • Ethynylcytidine

    CAS:
    <p>Ethynylcytidine is a nucleoside antimetabolite.</p>
    Fórmula:C11H13N3O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:267.24

    Ref: TM-TQ0006

    50mg
    Descontinuado
    100mg
    Descontinuado
    Produto descontinuado
  • 5'-DMT-3'-TBDMS-ibu-rG

    CAS:
    <p>5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.</p>
    Fórmula:C41H51N5O8Si
    Cor e Forma:Solid
    Peso molecular:769.96

    Ref: TM-T40919

    Produto descontinuado
  • Tanuxiciclib

    CAS:
    <p>Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor, specifically designed to interfere with cell cycle progression by inhibiting the activity of CDKs, which are crucial regulators of cell division.</p>
    Fórmula:C15H13FN6O
    Cor e Forma:Solid
    Peso molecular:312.308

    Ref: TM-T39404

    Produto descontinuado
  • NSC639828

    CAS:
    <p>NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.</p>
    Fórmula:C18H13BrClN5O3
    Cor e Forma:Solid
    Peso molecular:462.69

    Ref: TM-T38742

    Produto descontinuado
  • GSK-3/CDK5/CDK2-IN-1

    CAS:
    <p>GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].</p>
    Fórmula:C21H22N4O2
    Cor e Forma:Solid
    Peso molecular:362.433

    Ref: TM-T35555

    Produto descontinuado
  • N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine

    CAS:
    <p>N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine, catalog number T66118 and CAS number 64325-78-6, is a valuable organic compound for life sciences research.</p>
    Fórmula:C38H35N5O6
    Cor e Forma:Solid
    Peso molecular:657.727

    Ref: TM-T66118

    Produto descontinuado
  • 5'-O-DMT-N6-ibu-dA

    CAS:
    <p>5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.</p>
    Fórmula:C35H37N5O6
    Cor e Forma:Solid
    Peso molecular:623.71

    Ref: TM-T39332

    Produto descontinuado
  • Formycin A

    CAS:
    <p>Formycin A shows antitumor and antiviral activities. Formycin A , a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM.</p>
    Fórmula:C10H13N5O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:267.24

    Ref: TM-T11312

    5mg
    Descontinuado
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  • 5'-O-TBDMS-dT

    CAS:
    <p>5’-O-TBDMS-dT is a nucleoside with protective and modification effects.</p>
    Fórmula:C16H28N2O5Si
    Cor e Forma:Solid
    Peso molecular:356.49

    Ref: TM-T37145

    1ml*10 (DMSO)
    Descontinuado
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  • 2'-Deoxy-2'-fluoro-5-iodouridine

    CAS:
    <p>2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside, specifically a fluoro-modified and halo-nucleoside.</p>
    Fórmula:C9H10FIN2O5
    Cor e Forma:Solid
    Peso molecular:372.09

    Ref: TM-TNU0622

    Produto descontinuado
  • 6-Amino-5-nitropyridin-2-one

    CAS:
    <p>6-Amino-5-nitropyridin-2-one, a pyridine derivative, serves as a nucleobase within hachimoji DNA, where it is specifically paired with 5-aza-7-deazaguanine.</p>
    Fórmula:C5H5N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:155.11

    Ref: TM-T19157

    50mg
    Descontinuado
    100mg
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  • Ribocil-C

    CAS:
    <p>Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.</p>
    Fórmula:C21H21N7OS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:419.5

    Ref: TM-T12722L

    50mg
    Descontinuado
    100mg
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  • MitoE10

    CAS:
    <p>MitoE10 is an effective mitochondrial targeting antioxidant.</p>
    Fórmula:C42H55O5PS
    Cor e Forma:Solid
    Peso molecular:702.92

    Ref: TM-T33406

    25mg
    Descontinuado
    50mg
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  • Tibremciclib

    CAS:
    <p>Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].</p>
    Fórmula:C28H32F2N8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:518.6

    Ref: TM-T79863

    5mg
    Descontinuado
    50mg
    Descontinuado
    Produto descontinuado
  • PHI-101

    CAS:
    <p>PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.</p>
    Fórmula:C19H19FN4O2S
    Pureza:99.4%
    Cor e Forma:Solid
    Peso molecular:386.44

    Ref: TM-T81490

    1mg
    Descontinuado
    5mg
    Descontinuado
    10mg
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    25mg
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    100mg
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    200mg
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  • YK-2168

    CAS:
    <p>YK-2168 is a differentiated selective inhibitor of CDK9.</p>
    Fórmula:C16H18ClN5
    Cor e Forma:Solid
    Peso molecular:315.80

    Ref: TM-T200769

    10mg
    Descontinuado
    25mg
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    50mg
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    100mg
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