Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(94 produtos)
- CDK(500 produtos)
- Ciclo celular/Parada(4 produtos)
- Chk(42 produtos)
- DYRK(48 produtos)
- Dinamina(23 produtos)
- Ferroptose(215 produtos)
- HSP(169 produtos)
- Integrinas(224 produtos)
- Cinesina(66 produtos)
- LIM Quinase(19 produtos)
- Microtúbulo associado(261 produtos)
- PKC(102 produtos)
- PLK(28 produtos)
- ROCK(70 produtos)
- Rho(2 produtos)
- Wee1(15 produtos)
- c-Myc(69 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"
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DENV-IN-2
CAS:<p>DENV-IN-2 inhibits dengue virus replication (EC50: 0.016 nM), affects all serotypes (EC50: 0.013-0.029 nM). Derived from WO2018215315A1 6AB.</p>Fórmula:C29H26ClF3N2O6Cor e Forma:SolidPeso molecular:590.98TMX-2138
CAS:<p>TMX-2138 is a CDKs PROTAC degrader, with IC50 values of 8.7 nM for CDK1/cyclinB, 10.9 nM for CDK2/cyclinA, 7.0 nM for CDK5/p25, and 25.7 nM for CDK9/cyclinT1. It enhances the ubiquitination and degradation of CDKs and is utilized for ovarian cancer research.</p>Fórmula:C40H43BrFN9O11SCor e Forma:SolidPeso molecular:956.791Uridine triphosphate 13C9,15N2 sodium
CAS:<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Fórmula:C9H1415N2NaO15P3Cor e Forma:SolidPeso molecular:517.04Activated Protein C (390-404), human TFA
<p>APC's 390-404 peptide region key to anticoagulation, binds antibodies/proteins, inactivates cofactors Va/VIIIa.</p>Fórmula:C93H131F3N22O25Pureza:98%Cor e Forma:SolidPeso molecular:2014.165-Caroxy uracil-1-yl acetic acid benzyl ester
<p>5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>Fórmula:C14H12N2O6Cor e Forma:SolidPeso molecular:304.25Etrolizumab
CAS:<p>MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.</p>Pureza:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Cor e Forma:LiquidBesufetamig
CAS:<p>Besufetamig is a bispecific antibody targeting programmed cell death protein 1 (PD-1) and the CD3ε chain. It modulates immune cell activity, exerting both immunosuppressive and antitumor effects. Besufetamig holds promise for cancer research.</p>Cor e Forma:Liquid2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Fórmula:C10H14N5Na2O8PCor e Forma:SolidPeso molecular:409.202DSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Cor e Forma:Odour SolidCDK9-IN-25
<p>CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.</p>Fórmula:C15H16FN5Pureza:98%Cor e Forma:SolidPeso molecular:285.32Risuteganib
CAS:<p>Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.</p>Fórmula:C22H39N9O11SPureza:98%Cor e Forma:SolidPeso molecular:637.66TH1085
CAS:<p>TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).</p>Fórmula:C17H21N3Pureza:99.99%Cor e Forma:SolidPeso molecular:267.37DHODH-IN-16
CAS:<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Fórmula:C24H25FN4O3Pureza:99.64%Cor e Forma:SolidPeso molecular:436.487-TFA-ap-7-Deaza-ddG
CAS:<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Fórmula:C16H16F3N5O4Cor e Forma:SolidPeso molecular:399.33Cotylenin A
CAS:<p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>Fórmula:C33H50O11Cor e Forma:SolidPeso molecular:622.744Erythromycin A dihydrate
CAS:<p>Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.</p>Fórmula:C37H69NO14Cor e Forma:SolidPeso molecular:751.94CDK2-IN-7
CAS:<p>CDK2-IN-7 is a CDK2 inhibitor for treating cancer ( IC 50 < 50 nM).</p>Fórmula:C24H30N6O4SCor e Forma:SolidPeso molecular:498.6wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Cor e Forma:Odour SolidEmicoron
CAS:<p>Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.</p>Fórmula:C52H58N6O4Pureza:98%Cor e Forma:SolidPeso molecular:831.055'-DMT-3'-TBDMS-Bz-rA
CAS:<p>5'-DMT-3'-TBDMS-Bz-rA is a nucleoside with protective and modification effects.</p>Fórmula:C44H49N5O7SiCor e Forma:SolidPeso molecular:787.975-O-benzoyl-1,2-O-isopropylidene-α-D-erythro-pent-3-ulofuranose
CAS:<p>5-O-benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose is a Carbohydrate; Used for modified nucleoside.</p>Fórmula:C15H16O6Cor e Forma:SolidPeso molecular:292.282',3'-Dideoxy-3'-fluorouridine
CAS:<p>Nucleoside Derivatives - 2’,3’-Dideoxy nucleosides, Fluoro-modified nucleosides, 3’-Modified nucleosides; Drugs and Inhibitors; Anti-HIV agent</p>Fórmula:C9H11FN2O4Cor e Forma:SolidPeso molecular:230.193'-O-(2-Azidoethyl)adenosine
<p>Nucleoside Derivatives - 3’-Modified nucleosides; Azido-nucleosides</p>Cor e Forma:Soild3'-O-t-Bulyldimethylsilyl thymidine
CAS:<p>Nucleosides - 2’-deoxynucleoside</p>Fórmula:C16H28N2O5SiCor e Forma:SolidPeso molecular:356.492'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine
CAS:<p>2'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine is a Nucleoside Derivative - 6-Aza-uridine; Fluoro-modified nucleoside; Arabino nucleoside.</p>Fórmula:C8H10FN3O5Cor e Forma:SolidPeso molecular:247.18N6-Acetyl adenosine
CAS:<p>Nucleoside Derivatives –Naturally modified ribo-nucleosides;Other modified nucleosides</p>Fórmula:C12H15N5O5Cor e Forma:SolidPeso molecular:309.28N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine
<p>N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine is a Nucleoside Derivative - 2'-Modified nucleoside, N-Methylated/alkylated nucleoside, Fluoro-modified nucleoside.</p>Cor e Forma:Soild2'-O-(2-Methoxyethyl) inosine
CAS:<p>2'-O-(2-Methoxyethyl) inosine is a Nucleoside Derivative - 2'-Modified nucleoside.</p>Fórmula:C13H18N4O6Cor e Forma:SolidPeso molecular:326.312'-O-Acetyl-3'-azido-5'-O-(p-Toluoyl))-3'-deoxyuridine
CAS:<p>Nucleoside Derivatives - 3’-Modified nucleoside, Azido-nucleosides</p>Fórmula:C19H19N5O7Cor e Forma:SolidPeso molecular:429.382'-β-C-Methyl inosine
CAS:<p>2'-beta-C-Methyl inosine (2'-C-Methyl inosine) is an HCV RNA polymerase inhibitor with antiviral activity and may be used in studies to treat hcv infections.</p>Fórmula:C11H14N4O5Cor e Forma:SolidPeso molecular:282.252'-Deoxy-5,N4-dimethylcytidine
CAS:<p>2'-Deoxy-5,N4-dimethylcytidine is a Nucleoside Derivative - N-Methylated nucleoside.</p>Fórmula:C11H17N3O4Cor e Forma:SolidPeso molecular:255.275-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine
CAS:<p>Nucleoside Derivatives - C-Nucleosides, Pyridine nucleosides</p>Fórmula:C39H39NO5Cor e Forma:SolidPeso molecular:601.736-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine
CAS:<p>6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine is a Nucleoside Derivative - Other modified nucleoside.</p>Fórmula:C10H13N5O3Cor e Forma:SolidPeso molecular:251.248-Nitroguanosine
CAS:<p>8-Nitroguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.</p>Fórmula:C10H12N6O7Cor e Forma:SolidPeso molecular:328.243'-deoxy-3'-fluoro-β-D-xylo-inosine
CAS:<p>Nucleoside Derivatives - Fluoro-modified nucleosides; 3’-Modified nucleosides; Xylo-nucleosides</p>Fórmula:C10H11FN4O4Cor e Forma:SolidPeso molecular:270.222'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine
CAS:<p>2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-</p>Fórmula:C19H18F2N2O7Cor e Forma:SolidPeso molecular:424.352'-Deoxy-2'-fluoro-5-hydroxymethyl arabinouridine
CAS:<p>Nucleoside Derivatives - Fluoro-modified nucleosides; 2’-Modified nucleosides; 5-Modified pyrimidine nucleosides; Metabolite of FMAU</p>Fórmula:C10H13FN2O6Cor e Forma:SolidPeso molecular:276.222'-Deoxy-6-azauridine
CAS:<p>2’-Deoxy-6-azauridine is a useful organic compound for research related to life sciences. The catalog number is TNU1081 and the CAS number is 20500-29-2.</p>Fórmula:C8H11N3O5Cor e Forma:SolidPeso molecular:229.192',3',5'-Tri-O-Benzoyl-4'-thiouridine
CAS:<p>2',3',5'-Tri-O-Benzoyl-4'-thiouridine is a Thio-nucleoside.</p>Fórmula:C30H24N2O8SCor e Forma:SolidPeso molecular:572.593'-O-t-Butyldimethylsilyl adenosine
CAS:<p>3'-O-t-Butyldimethylsilyl adenosine is a Nucleoside; Used for special nucleoside modification.</p>Fórmula:C16H27N5O4SiCor e Forma:SolidPeso molecular:381.56-Deoxo-8-oxo-3'-deoxy-guanosine
<p>6-Deoxo-8-oxo-3’-deoxy-guanosine is a useful organic compound for research related to life sciences and the catalog number is TNU1451.</p>Cor e Forma:Soild(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol
CAS:<p>(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is a Nucleoside Derivative - C-nucleoside; Fluoro-modified nucleoside.</p>Fórmula:C11H12F2O4Cor e Forma:SolidPeso molecular:246.21DMTr-LNA-G(iBu)-3'-CED-phosphoramidite
CAS:<p>Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phosphoramidites</p>Fórmula:C45H54N7O9PCor e Forma:SolidPeso molecular:867.935-(Aminomethyl)-2-thiouridine
CAS:<p>Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Thio-nucleosides; Amino nucleosides; Naturally modified ribo-nucleosides</p>Fórmula:C10H15N3O5SCor e Forma:SolidPeso molecular:289.31N6-Methyl-xylo-adenosine
CAS:<p>N6-Methyl-xylo-adenosine is a Nucleoside Derivative - Xylo-nucleoside;6-Substituted purine nucleoside.</p>Fórmula:C11H15N5O4Cor e Forma:SolidPeso molecular:281.272-Deoxy-2'-deoxyuridine
CAS:<p>2-Deoxy-2'-deoxyuridine is a Nucleoside Derivative - 2-Deoxy uridine.</p>Fórmula:C9H12N2O4Cor e Forma:SolidPeso molecular:212.22-Methoxy-2'-deoxyadenosine
CAS:<p>2-Methoxy-2'-deoxyadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.</p>Fórmula:C11H15N5O4Cor e Forma:SolidPeso molecular:281.272'-Deoxy-2'-iodouridine
CAS:<p>2'-Deoxy-2'-iodouridine is a Halo-nucleoside.</p>Fórmula:C9H11IN2O5Cor e Forma:SolidPeso molecular:354.1DHPS-IN-1
CAS:<p>DHPS-IN-1, a chemical compound, demonstrates exceptional inhibitory potency against melanoma cells, as evidenced by its IC50 value of 0.014 μM.</p>Fórmula:C17H13BrClN3O2Cor e Forma:SolidPeso molecular:406.668-Chloroguanosine
CAS:<p>8-Chloroguanosine is a Nucleoside Derivative - Halo-nucleoside, 8-Modified purine nucleoside.</p>Fórmula:C10H12ClN5O5Cor e Forma:SolidPeso molecular:317.69
![6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTNU1427.webp&w=3840&q=75)
