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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3936 produtos de "Ciclo celular/Ponto de verificação"

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produtos por página.
  • Firategrast

    CAS:
    Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous
    Fórmula:C27H27F2NO6
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:499.5

    Ref: TM-TQ0291

    1mg
    44,00€
    1mL*10mM (DMSO)
    92,00€
    5mg
    93,00€
    10mg
    133,00€
    25mg
    268,00€
    50mg
    439,00€
    100mg
    708,00€
    200mg
    964,00€
  • Cytembena

    CAS:
    Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.
    Fórmula:C11H8BrNaO4
    Pureza:99.7%
    Cor e Forma:White Powder
    Peso molecular:307.07

    Ref: TM-T27112

    1mg
    88,00€
    5mg
    190,00€
    10mg
    279,00€
    25mg
    527,00€
    50mg
    702,00€
    100mg
    982,00€
    500mg
    1.963,00€
  • Rho-Kinase-IN-1

    CAS:
    Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.
    Fórmula:C20H24N4S
    Pureza:99.8%
    Cor e Forma:Solid
    Peso molecular:352.5

    Ref: TM-T12721

    1mg
    71,00€
    1mL*10mM (DMSO)
    105,00€
    5mg
    138,00€
    10mg
    205,00€
    25mg
    358,00€
    50mg
    502,00€
    100mg
    665,00€
    200mg
    893,00€
  • AzddMeC

    CAS:
    AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infection
    Fórmula:C10H14N6O3
    Pureza:97.14% - 99.62%
    Cor e Forma:Solid
    Peso molecular:266.26

    Ref: TM-T26726

    1mg
    48,00€
    5mg
    96,00€
    10mg
    156,00€
    25mg
    304,00€
    50mg
    482,00€
    100mg
    803,00€
  • YK-2-69

    CAS:
    YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.
    Fórmula:C25H27FN8OS
    Pureza:98.61% - 99.64%
    Cor e Forma:Solid
    Peso molecular:506.6

    Ref: TM-T69564

    1mg
    264,00€
    5mg
    650,00€
    10mg
    888,00€
  • ITX3

    CAS:
    ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.
    Fórmula:C22H17N3OS
    Pureza:97.28%
    Cor e Forma:Solid
    Peso molecular:371.45

    Ref: TM-T15602

    5mg
    39,00€
    10mg
    67,00€
    25mg
    133,00€
    50mg
    251,00€
    100mg
    353,00€
  • CD532

    CAS:
    CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.
    Fórmula:C26H25F3N8O
    Pureza:99.99%
    Cor e Forma:Solid
    Peso molecular:522.52

    Ref: TM-T50110

    50mg
    A consultar
    1mg
    37,00€
    5mg
    79,00€
    10mg
    113,00€
    25mg
    215,00€
  • AS 1892802

    CAS:
    AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.
    Fórmula:C20H19N3O2
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:333.38

    Ref: TM-T22037

    1mg
    49,00€
    5mg
    92,00€
    1mL*10mM (DMSO)
    109,00€
    10mg
    166,00€
    25mg
    358,00€
    50mg
    530,00€
    100mg
    758,00€
    200mg
    1.044,00€
  • AS-0141

    CAS:
    AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM),具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶,在细胞周期中对 DNA 复制的启动至关重要。
    Fórmula:C21H22F3N5O4
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:465.43

    Ref: TM-T10728

    1mg
    60,00€
    5mg
    138,00€
    10mg
    200,00€
    25mg
    335,00€
  • 9-Isopropylolomoucine

    CAS:
    9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.
    Fórmula:C17H22N6O
    Pureza:99.82%
    Cor e Forma:Solid
    Peso molecular:326.4

    Ref: TM-T23589

    1mg
    315,00€
    1mL*10mM (DMSO)
    607,00€
    5mg
    745,00€
    10mg
    1.018,00€
    25mg
    1.431,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
    500mg
    4.410,00€
  • (S)-PF-06873600

    CAS:
    (S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.
    Fórmula:C20H27F2N5O4S
    Pureza:98.59%
    Cor e Forma:Solid
    Peso molecular:471.52

    Ref: TM-T12809

    2mg
    37,00€
    5mg
    57,00€
    10mg
    90,00€
    25mg
    154,00€
    50mg
    248,00€
    100mg
    393,00€
  • DS18561882

    CAS:
    DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.
    Fórmula:C28H31F3N4O6S
    Pureza:98.19% - >99.99%
    Cor e Forma:Solid
    Peso molecular:608.63

    Ref: TM-T11103

    1mg
    109,00€
    5mg
    260,00€
    1mL*10mM (DMSO)
    358,00€
    10mg
    409,00€
    25mg
    737,00€
    50mg
    1.198,00€
    100mg
    1.611,00€
  • INDY

    CAS:
    INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.
    Fórmula:C12H13NO2S
    Pureza:99.26%
    Cor e Forma:Solid
    Peso molecular:235.3

    Ref: TM-T15579

    5mg
    57,00€
    1mL*10mM (DMSO)
    62,00€
    10mg
    75,00€
    25mg
    105,00€
    50mg
    149,00€
  • NSC16168

    CAS:
    NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.
    Fórmula:C17H15NO9S3
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:473.5

    Ref: TM-T16351

    1mg
    60,00€
    5mg
    130,00€
    1mL*10mM (DMSO)
    135,00€
    10mg
    200,00€
    25mg
    338,00€
    50mg
    497,00€
    100mg
    708,00€
    200mg
    964,00€
  • 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

    CAS:
    5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits hybridization and mismatch discrimination capabilities similar to LNA, and shows resistance to exonuclease digestion [1].
    Fórmula:C49H54N7O8P
    Cor e Forma:Solid
    Peso molecular:899.97

    Ref: TM-T74702

    1mg
    288,00€
    5mg
    702,00€
    10mg
    1.000,00€
    25mg
    1.478,00€
    50mg
    1.941,00€
    100mg
    2.617,00€
  • WEE1-IN-4

    CAS:
    Wee1 Inhibitor I is an ATP-binding site-targeting Wee1 inhibitor.
    Fórmula:C20H11ClN2O3
    Cor e Forma:Solid
    Peso molecular:362.77

    Ref: TM-T23869

    1mg
    852,00€
  • CCT251455

    CAS:
    CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.
    Fórmula:C26H26ClN7O2
    Pureza:99.1% - 99.79%
    Cor e Forma:Solid
    Peso molecular:503.98

    Ref: TM-T14906

    1mg
    154,00€
    5mg
    371,00€
    1mL*10mM (DMSO)
    413,00€
    10mg
    620,00€
    25mg
    1.341,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • WRN inhibitor 5

    CAS:
    WRN Inhibitor 5 (Example 157), a cyclic vinyl sulfone-based compound, serves as an inhibitor of Werner Syndrome ATP-dependent helicase enzyme (WRN).
    Fórmula:C23H20N2O6S
    Cor e Forma:Solid
    Peso molecular:452.48

    Ref: TM-T80772

    5mg
    A consultar
    50mg
    A consultar
  • GSK2163632A

    CAS:
    GSK2163632A is an insulin-like growth factor 1 receptor inhibitor that acts by binding to a novel region of the GRK active site cleft.
    Fórmula:C27H32N8O3S
    Cor e Forma:Solid
    Peso molecular:548.66

    Ref: TM-T24106

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • LDC3140

    CAS:
    LDC3140 is a potent inhibitor of Cyclin-dependent kinase 7 (CDK7).
    Fórmula:C23H33N7O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:423.55

    Ref: TM-T27805

    25mg
    1.872,00€
    50mg
    2.452,00€
    100mg
    3.230,00€
  • 5,6,7,8-Tetrahydro-8-deazahomofolic acid

    CAS:
    5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.
    Fórmula:C21H26N6O6
    Cor e Forma:Solid
    Peso molecular:458.47

    Ref: TM-T24981

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • KM05382

    CAS:
    KM05382 inhibits CDK9 and the transcription of GAPDH.
    Fórmula:C20H19ClN2O3S2
    Cor e Forma:Solid
    Peso molecular:434.96

    Ref: TM-T27735

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • CT1113

    CAS:
    CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX
    Fórmula:C25H29N5O2S
    Cor e Forma:Solid
    Peso molecular:463.6

    Ref: TM-T79187

    5mg
    A consultar
    50mg
    A consultar
  • Methotrexate-γ-aspartate

    CAS:
    Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.
    Fórmula:C24H27N9O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:569.53

    Ref: TM-T24457

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Antifolate C1

    CAS:
    Antifolate C1 blocks purine creation, favors uptake via folate receptors/PCFT over RFC.
    Fórmula:C19H21N5O6S
    Cor e Forma:Solid
    Peso molecular:447.46

    Ref: TM-T26635

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • 5-DACTHF

    CAS:
    5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.
    Fórmula:C19H24N6O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:432.43

    Ref: TM-T24980

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Diazoketone methotrexate

    CAS:
    Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.
    Fórmula:C21H22N10O4
    Cor e Forma:Solid
    Peso molecular:478.46

    Ref: TM-T25322

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • IIIM-290

    CAS:
    IIIM-290 is an oral CDK inhibitor (IC50s: 90 and 94 nM for CDK2/A and CDK9/T1).
    Fórmula:C23H21Cl2NO5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:462.32

    Ref: TM-T11632

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • TAS-114

    CAS:
    TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.
    Fórmula:C21H29N3O6S
    Pureza:99.76%
    Cor e Forma:Solid
    Peso molecular:451.54

    Ref: TM-T13089

    2mg
    269,00€
  • Spirofylline

    CAS:
    Spirofylline is an agent of bronchodilator, has the potential for asthma and bronchitis and emphysema treatment.
    Fórmula:C24H28N6O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:480.52

    Ref: TM-T13899

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • BVDU 5′-Triphosphate

    CAS:
    BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.
    Fórmula:C11H16BrN2O14P3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:573.08

    Ref: TM-T80655

    5mg
    A consultar
    50mg
    A consultar
  • Zaurategrast

    CAS:
    Zaurategrast (CDP323) is an oral α4-integrin antagonist that blocks VCAM-1 interactions and is used to study immune cell trafficking.
    Fórmula:C26H25BrN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:521.41

    Ref: TM-T17286

    1mg
    72,00€
    5mg
    166,00€
  • ROCK-IN-7

    CAS:
    ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].
    Fórmula:C17H17N3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:327.4

    Ref: TM-T79080

    5mg
    A consultar
    50mg
    A consultar
  • DNA polymerase-IN-1

    CAS:
    DNA polymerase-IN-1 exhibits antiproliferative activity against tumor cells and inhibits Taq DNA polymerase as a DNA polymerase inhibitor.
    Fórmula:C10H7ClO4
    Pureza:99.16%
    Cor e Forma:Solid
    Peso molecular:226.61

    Ref: TM-T80644

    1mg
    175,00€
    5mg
    434,00€
    10mg
    622,00€
    25mg
    973,00€
    50mg
    1.341,00€
    100mg
    1.773,00€
  • Lamifiban

    CAS:
    Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.
    Fórmula:C24H28N4O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:468.5

    Ref: TM-T25607

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • ROCK2-IN-6 hydrochloride

    CAS:
    ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂,适用于研究ROCK介导的疾病、自身免疫性病症与炎症。
    Fórmula:C26H22ClF2N7O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:521.95

    Ref: TM-T78205

    2mg
    263,00€
  • NVS-SM2

    CAS:
    NVS-SM2 boosts SMN2 splicing, enhances exon 7 inclusion, and raises SMN protein levels orally.
    Fórmula:C23H30N6O
    Cor e Forma:Solid
    Peso molecular:406.52

    Ref: TM-T33764

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • PLK1/p38γ-IN-1

    CAS:
    PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular
    Fórmula:C21H26ClN3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:387.9

    Ref: TM-T81441

    5mg
    A consultar
    50mg
    A consultar
  • NTRC 0066-0

    CAS:
    NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.
    Fórmula:C33H39N7O2
    Pureza:98.30%
    Cor e Forma:Solid
    Peso molecular:565.71

    Ref: TM-T28216

    2mg
    139,00€
  • SC-52012

    CAS:
    SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.
    Fórmula:C25H30N4O6
    Pureza:97.20%
    Cor e Forma:Solid
    Peso molecular:482.53

    Ref: TM-T12857

    1mg
    630,00€
    5mg
    1.620,00€
  • Chroman 1

    CAS:
    Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).
    Fórmula:C24H28N4O4
    Pureza:99.67% - 99.84%
    Cor e Forma:Solid
    Peso molecular:436.5

    Ref: TM-T14960

    1mg
    73,00€
    5mg
    160,00€
    1mL*10mM (DMSO)
    173,00€
    10mg
    250,00€
    25mg
    430,00€
    50mg
    645,00€
    100mg
    888,00€
  • UNC-2170

    CAS:
    UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.
    Fórmula:C14H21BrN2O
    Pureza:97.44%
    Cor e Forma:Solid
    Peso molecular:313.23

    Ref: TM-T24925

    5mg
    46,00€
    1mL*10mM (DMSO)
    57,00€
    10mg
    71,00€
    25mg
    138,00€
    50mg
    200,00€
    100mg
    284,00€
    200mg
    391,00€
  • SB-267268

    CAS:
    SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).
    Fórmula:C22H24F3N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:451.44

    Ref: TM-T16851

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • 5'-ODMT cEt m5U Phosphoramidite (Amidite)

    CAS:
    5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].
    Fórmula:C42H51N4O9P
    Cor e Forma:Solid
    Peso molecular:786.85

    Ref: TM-T74705

    10mg
    36,00€
    25mg
    49,00€
    50mg
    68,00€
    100mg
    101,00€
  • m-Se3

    CAS:
    m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].
    Fórmula:C29H23IN2Se
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:605.37

    Ref: TM-T79872

    5mg
    A consultar
    50mg
    A consultar
  • Fosfluridine tidoxil

    CAS:
    Fosfluridine tidoxil, a thymidylate synthase inhibitor, is used potentially for the treatment of colorectal cancer, and breast cancer.
    Fórmula:C34H62FN2O10PS
    Cor e Forma:Solid
    Peso molecular:740.9

    Ref: TM-T27349

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • DCB-3503

    CAS:
    DCB-3503, a tylophorine analog, may fight cancer and aid immunosuppression by hindering protein synthesis and modulating HSC70 ATPase function.
    Fórmula:C24H27NO5
    Cor e Forma:Solid
    Peso molecular:409.47

    Ref: TM-T27128

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • 3-Cyanovinylcarbazole phosphoramidite

    CAS:
    3-Cyanovinylcarbazole phosphoramidite: an antiviral, hinders viral DNA synthesis, modifies ribonucleotides.
    Fórmula:C50H53N4O6P
    Cor e Forma:Solid
    Peso molecular:836.95

    Ref: TM-T74188

    5mg
    873,00€
    50mg
    1.665,00€
    100mg
    2.250,00€
  • L 738167

    CAS:
    L 738167 is a potent antagonist of the long-acting fibrinogen receptor.
    Fórmula:C25H34N6O6S
    Cor e Forma:Solid
    Peso molecular:546.64

    Ref: TM-T24353

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • JNJ-26076713

    CAS:
    JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.
    Fórmula:C29H38N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:490.64

    Ref: TM-T27670

    25mg
    4.374,00€