Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2615 produtos de "Cromatina/Epigenética"
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ZLD1039
CAS:ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.Fórmula:C36H48N6O3Pureza:99.5%Cor e Forma:SolidPeso molecular:612.8Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Fórmula:C13H11ClFN5Cor e Forma:SolidPeso molecular:291.71SC-10
CAS:SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Fórmula:C17H22ClNO2SPureza:99.24% - 99.58%Cor e Forma:SolidPeso molecular:339.88UMB-32
CAS:UMB-32: Potent, selective BRD4 inhibitor, Kd 550 nM, IC50 637 nM, also targets TAF1.Fórmula:C21H23N5OCor e Forma:SolidPeso molecular:361.44Bromodomain inhibitor-10
CAS:Bromodomain inhibitor-10 (compound 128) suppresses BRD4-1/2 with Kd 15 nM/2.5 μM and curbs IL12p40 production.Fórmula:C20H20N4O3Cor e Forma:SolidPeso molecular:364.4FNDR-20123 free base
CAS:FNDR-20123 is a safe, oral first-in-class anti-malarial HDAC inhibitor with low IC50s against Plasmodium and human HDACs.Fórmula:C21H23N5O2Cor e Forma:SolidPeso molecular:377.44K00135
CAS:K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.Fórmula:C18H18N4OPureza:98.16%Cor e Forma:SolidPeso molecular:306.36Tinostamustine HCl
CAS:Tinostamustine (EDO-S101) is an alkylating HDACi fusion molecule, enhancing potency and overcoming drug resistance.Fórmula:C19H29Cl3N4O2Cor e Forma:SolidPeso molecular:451.82CAY10669
CAS:CAY10669 inhibits PCAF (IC50 = 662 μM), is twice as potent as anacardic acid, and reduces H4 acetylation in HepG2 cells at 30-60 μM.Fórmula:C20H22O4Cor e Forma:SolidPeso molecular:326.39LT052
CAS:LT052 is a BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 signaling inflammatory pathway.Fórmula:C22H19N5O4SPureza:98.82%Cor e Forma:SolidPeso molecular:449.48UNC6212 (Kme2)
UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM .Fórmula:C39H53N7O11Cor e Forma:SolidPeso molecular:795.88OM-137
CAS:OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Fórmula:C13H14N4O3SCor e Forma:SolidPeso molecular:306.34TC-E 5001
CAS:dual tankyrase (TNKS) inhibitorFórmula:C20H19N5O3SPureza:98%Cor e Forma:SolidPeso molecular:409.46Givinostat hydrochloride
CAS:Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.Fórmula:C24H28ClN3O4Pureza:99.39%Cor e Forma:SolidPeso molecular:457.95Ref: TM-T6279L
1mg35,00€5mg75,00€1mL*10mM (DMSO)77,00€10mg120,00€25mg240,00€50mg416,00€100mg663,00€200mg888,00€OXF BD 02
CAS:OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity.Fórmula:C18H17NO3Pureza:98.25%Cor e Forma:SolidPeso molecular:295.33Raxofelast
CAS:Raxofelast (IRFI-016), a vitamin-like, hydrophilic antioxidant, mitigates ischemia-reperfusion in testis and may treat diabetic issues and atherosclerosis.Fórmula:C15H18O5Pureza:99.74% - 99.97%Cor e Forma:SolidPeso molecular:278.3JAK1-IN-8
CAS:JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
Fórmula:C22H23FN4O3SPureza:98.4%Cor e Forma:SolidPeso molecular:442.51DCPLA-ME
CAS:DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerativeFórmula:C21H38O2Pureza:99.80%Cor e Forma:SolidPeso molecular:322.53Ref: TM-T10980
1mg62,00€5mg126,00€1mL*10mM (DMSO)138,00€10mg172,00€25mg350,00€50mg572,00€100mg772,00€200mg1.054,00€Butyrolactone 3
CAS:Butyrolactone 3 (MB-3) is a Gcn5 inhibitor with weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and can be used in cancer.Fórmula:C9H12O4Pureza:98.99% - 99.5%Cor e Forma:SolidPeso molecular:184.19NSC 694623
CAS:NSC 694623: Potent HAT inhibitor, IC50=15.9 μM against PCAF, anti-cancer properties.Fórmula:C16H16N2OSPureza:99.9%Cor e Forma:SolidPeso molecular:284.38
