Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2624 produtos de "Cromatina/Epigenética"
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HDAC/HSP90-IN-3
CAS:HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.Fórmula:C26H33N5O6Cor e Forma:SolidPeso molecular:511.57PARP7-IN-16
CAS:PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively.Fórmula:C25H26FN4NaO4Pureza:98%Cor e Forma:SolidPeso molecular:488.49BChE/HDAC6-IN-1
CAS:BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor that exhibits potent and selective inhibition with IC50 values of 4 nM for BChE and 8.9 nM for HDAC6.Fórmula:C34H43N5O5Pureza:98%Cor e Forma:SolidPeso molecular:601.74NSC756093
CAS:NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies.Fórmula:C20H19NO4Pureza:99.92%Cor e Forma:SolidPeso molecular:337.37Ref: TM-T24557
1mg44,00€5mg96,00€1mL*10mM (DMSO)111,00€10mg148,00€25mg313,00€50mg465,00€100mg662,00€500mg1.333,00€KP-544
CAS:KP-544 is an agent of neurotrophin potentiator.Fórmula:C18H19ClN4OPureza:98%Cor e Forma:SolidPeso molecular:342.82JAK-IN-17
"JAK-IN-17: Potent JAK inhibitor for studying ocular, skin, and respiratory diseases."Fórmula:C33H38F2N6O8Cor e Forma:SolidPeso molecular:684.69GSK-A
CAS:GSK-A is a Histone Lysine Methyltransferase EZH2 inhibitor.Fórmula:C21H25N5O2Cor e Forma:SolidPeso molecular:379.46KDM2B-IN-1
CAS:KDM2B-IN-1: Potent, specific KDM2B histone demethylase inhibitor for hyperproliferative disease research.Fórmula:C21H30N4O2SCor e Forma:SolidPeso molecular:402.56PHD-IN-1
CAS:PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of ≤5 nM.Fórmula:C24H23N7O2Pureza:98%Cor e Forma:SolidPeso molecular:441.49Bisegliptin
CAS:Bisegliptin(KRP-104) is a small molecule compound with anti-diabetic activity.Fórmula:C18H26FN3O3Pureza:98%Cor e Forma:SolidPeso molecular:351.42GNE-955
CAS:GNE-955 is a potent and orally active inhibitor of pan Pim kinase (Kis: 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively).Fórmula:C22H24N8OPureza:98%Cor e Forma:SolidPeso molecular:416.48Tyk2-IN-9
CAS:Tyk2-IN-9: selective Tyk-2 inhibitor, IC50 of 0.076 nM (TYK2-JH2), 1.8 nM (JAK1-JH2), for inflammation/autoimmune research.Fórmula:C20H17N9Pureza:98%Cor e Forma:SolidPeso molecular:383.41NMS-P515
CAS:NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity.Fórmula:C21H29N3O2Pureza:98%Cor e Forma:SolidPeso molecular:355.47SIRT5 inhibitor 7
CAS:SIRT5 inhibitor 7 , a substrate-competitive and selective SIRT5 inhibitor, significantly attenuated renal dysfunction and pathological damage in AKI mice.Fórmula:C28H32ClN7O3SPureza:99.77%Cor e Forma:SolidPeso molecular:582.12GNE-207
CAS:GNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM).Fórmula:C29H30N6O3Pureza:98%Cor e Forma:SolidPeso molecular:510.59JAK-IN-26
CAS:JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with favorable pharmacokinetic properties, exhibiting potency inFórmula:C22H24N6O3Pureza:98%Cor e Forma:SolidPeso molecular:420.46FT895
CAS:FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity that inhibits HDAC11 expression and limits EV71 replication in vitro.Fórmula:C16H15F3N4O2Pureza:98.95% - >99.99%Cor e Forma:SolidPeso molecular:352.31Ref: TM-T11329
1mg92,00€5mg219,00€1mL*10mM (DMSO)241,00€10mg339,00€25mg570,00€50mg795,00€100mg1.108,00€AMPK-α1β1γ1 activator 1
CAS:AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, selectively activates the β1Fórmula:C25H24ClNO9Pureza:98%Cor e Forma:SolidPeso molecular:517.91PARP1-IN-7
CAS:PARP1-IN-7 functions as an anticancer agent by inhibiting poly(ADP-ribose) polymerase-1 (PARP1).Fórmula:C24H23N5OCor e Forma:SolidPeso molecular:397.47Ro 32-0432 hydrochloride
CAS:Ro 32-0432 is a selective, ATP-competitive, oral pan-PKC inhibitor exhibiting inhibitory effects on PKCα, PKCβI, PKCβII, PKCγ, and PKCε.Fórmula:C28H28N4O2Pureza:98%Cor e Forma:SolidPeso molecular:452.55
