Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2633 produtos de "Cromatina/Epigenética"
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HDAC6-IN-8
CAS:Compound 12C, with altered cap groups, shows wide-range enzyme inhibition; 9m and 9q target HDAC6 specifically.Fórmula:C23H17BrFN5O3Pureza:98%Cor e Forma:SolidPeso molecular:510.32Sirtuin modulator 1
CAS:Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.Fórmula:C31H32ClN5O2S2Pureza:99.63%Cor e Forma:SolidPeso molecular:606.2CBB1007 hydrochloride
CAS:CBB1007 Hcl inhibits LSD1 selectively (IC50=5.27μM), blocks H3K4 demethylation, activates genes; less effect on other cells/tissues.Fórmula:C27H39Cl5N8O4Cor e Forma:SoildPeso molecular:716.91JAK-IN-25
CAS:JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3.Fórmula:C19H17N5O4Pureza:98%Cor e Forma:SolidPeso molecular:379.37EPZ-030456
CAS:EPZ-030456 is an effective and selective inhibitor of the SMYD3.Fórmula:C28H34ClN5O4SCor e Forma:SolidPeso molecular:572.12XDM-CBP
CAS:XDM-CBP is an effective and selective CBP/p300 bromodomain inhibitor.Fórmula:C21H22N2O4Pureza:98%Cor e Forma:SolidPeso molecular:366.41KH-3
CAS:KH-3: HuR inhibitor, IC50 0.35 μM, halts cell growth, blocks HuR-FOXQ1 mRNA, curbs breast cancer invasion, slows lung colony growth.Fórmula:C21H22N2O4S2Cor e Forma:SolidPeso molecular:430.54T-448 free base
CAS:T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).Fórmula:C17H20N4OSPureza:98%Cor e Forma:SolidPeso molecular:328.43TCS 21311
CAS:TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Fórmula:C27H25F3N4O4Pureza:99.39% - ≥98%Cor e Forma:SolidPeso molecular:526.51JAK-IN-31
CAS:JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and ≤0.01 µM for Tyk2,Fórmula:C21H19N7O2S2Pureza:98%Cor e Forma:SolidPeso molecular:465.55MARK-IN-1
CAS:MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor, (IC50<0.25 nM).Fórmula:C22H23F2N7OSPureza:98%Cor e Forma:SolidPeso molecular:471.53TCS HDAC6 20b
CAS:TCS HDAC6 20b (HDAC6-IN-7) is an HDAC6 inhibitor that blocks the growth of breast cancer cells and can be used in cancer research.Fórmula:C26H44N2O4SPureza:>99.99%Cor e Forma:SolidPeso molecular:480.7QC6352
CAS:QC6352 is a selective and effective KDM4C inhibitor (IC50: 35 nM).Fórmula:C24H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:387.47CLB-016
CAS:CLB-016 is an inhibitor of hypoxia-inducible factor (HIF)-1.Fórmula:C17H20N6O3Pureza:98%Cor e Forma:SolidPeso molecular:356.38CBP/p300-IN-17
CAS:CBP/p300-IN-17 (compound 7) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.18 μM) and LK2 H3K27 (IC50: 0.69 μM).Fórmula:C25H28N4O3Cor e Forma:SolidPeso molecular:432.51Vafidemstat
CAS:Vafidemstat (ORY-2001) is a lysine-histone demethylase (LSD1)/MAO-B inhibitor for the study of neurological disorders.Fórmula:C19H20N4O2Pureza:99.53%Cor e Forma:SolidPeso molecular:336.39TC-A 2317 hydrochloride
CAS:TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.Fórmula:C19H29ClN6OPureza:98%Cor e Forma:SolidPeso molecular:392.93AAPK-25
CAS:AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.Fórmula:C21H13Cl2N3O2SPureza:97.05%Cor e Forma:SolidPeso molecular:442.32Ref: TM-T10215
1mg54,00€5mg118,00€1mL*10mM (DMSO)131,00€10mg172,00€25mg313,00€50mg469,00€100mg680,00€KDM5-C70
CAS:KDM5-C70 is an ethyl ester derivative of KDM5-C49.Fórmula:C17H28N4O3Pureza:97.63% - 99.86%Cor e Forma:SolidPeso molecular:336.43Ref: TM-T15648
2mg42,00€5mg58,00€1mL*10mM (DMSO)70,00€10mg84,00€25mg133,00€50mg233,00€100mg464,00€200mg663,00€500mg1.018,00€Bocodepsin hydrochloride
CAS:Bocodepsin hydrochloride (OKI-179) is a selective HDAC inhibitor with antitumor properties, efficacious via oral administration.Fórmula:C26H40ClN5O6S2Pureza:98%Cor e Forma:SolidPeso molecular:618.21
