CymitQuimica logo
Cromatina/Epigenética

Cromatina/Epigenética

Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.

Subcategorias de "Cromatina/Epigenética"

Foram encontrados 2490 produtos de "Cromatina/Epigenética"

Ordenar por

Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • EXQ-2d


    EXQ-2d is an inhibitor of tankyrase, effectively targeting TNKS1 and TNKS2 with IC50 values of 48.8 nM and 13.8 nM (pIC50=7.31 and 7.86), respectively. Additionally, EXQ-2d suppresses the WNT/β-catenin signaling pathway with an IC50 of 515 nM. It demonstrates antiproliferative activity in cancer cells COLO 320DM and RKO, with GI50 values of 4.9 μM and 77 μM, respectively.
    Fórmula:C18H17N3O3
    Cor e Forma:Solid
    Peso molecular:323.35

    Ref: TM-T205739

    10mg
    A consultar
    50mg
    A consultar
  • HD-TAC7

    CAS:
    HD-TAC7 is a PROTAC HDAC degrader; IC50s: HDAC1 (3.6μM), HDAC2 (4.2μM), HDAC3 (1.1μM); reduces NF-κB p65; researched for asthma, COPD.
    Fórmula:C33H32FN7O7
    Cor e Forma:Solid
    Peso molecular:657.65

    Ref: TM-T74514

    5mg
    A consultar
    50mg
    A consultar
  • (R)-SKBG-1

    CAS:
    (R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, effectively downregulating androgen receptor expression by targeting both AR-FL mRNA and AR-V7 mRNA
    Fórmula:C22H26ClN3O6S
    Pureza:97.25%
    Cor e Forma:Solid
    Peso molecular:495.98

    Ref: TM-T79156

    1mg
    79,00€
    5mg
    150,00€
    10mg
    268,00€
    25mg
    590,00€
    1mL*10mM (DMSO)
    164,00€
  • Ep300/CREBBP-IN-3

    CAS:
    Ep300/CREBBP-IN-3 inhibits Ep300 & CREBBP (IC50: 0.056 & 0.095 μM respectively); potential for cancer research.
    Fórmula:C26H25F4N5O3
    Cor e Forma:Solid
    Peso molecular:531.50

    Ref: TM-T73922

    5mg
    A consultar
    50mg
    A consultar
  • PROTAC BET degrader-2

    CAS:
    PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins (IC50 of 9.6 nM ).
    Fórmula:C41H42N10O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:770.84

    Ref: TM-T12559

    5mg
    379,00€
    10mg
    600,00€
    25mg
    1.111,00€
    50mg
    A consultar
    100mg
    A consultar
    1mL*10mM (DMSO)
    605,00€
  • BRD4-IN-4

    CAS:
    BRD4-IN-4 is a selective BRD4 inhibitor with an IC50 value of 6.83 μM for BRD4.BRD4-IN-4 selectively inhibits the proliferation of the MV4-11 cell line and
    Fórmula:C17H18N2O3S
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:330.4

    Ref: TM-T77339

    10mg
    34,00€
    25mg
    52,00€
    50mg
    77,00€
  • PRMT3-IN-4


    PRMT3-IN-4 (intermediate 15) is an inhibitor of Protein arginine methyltransferase 3 (PRMT3) and serves as the active control for SGC707. It can be utilized in the synthesis of PROTACs targeting PRMT3 and is applicable in research related to leukemia.
    Cor e Forma:Odour Solid

    Ref: TM-T200459

    10mg
    A consultar
    50mg
    A consultar
  • HDAC6-IN-42


    HDAC6-IN-42 (compound 2b) is an HDAC6 inhibitor with an IC50 of 0.009 μM, demonstrating significant anti-leukemia activity and synergistic effects with Decitabine, indicating its potential use in the research of Acute Myeloid Leukemia (AML).
    Fórmula:C24H28FN3O4
    Peso molecular:441.20638

    Ref: TM-T209868

    10mg
    A consultar
    50mg
    A consultar
  • PAD2-IN-2 TFA


    PAD2-IN-2 (cis-isomer of 1) TFA is an inhibitor of protein arginine deiminase 2 (PAD2). This molecule features an azobenzene photoswitch, enabling the optical regulation of PAD activity. Additionally, PAD2-IN-2 TFA inhibits the citrullination of histone H3.
    Fórmula:C28H27ClF3N7O3
    Cor e Forma:Solid
    Peso molecular:602.01

    Ref: TM-T203630

    10mg
    A consultar
    50mg
    A consultar
  • UNC10142


    UNC10142 (Compound 44) is a small-molecule antagonist of CHD1, with a binding IC50 value of 1.7 μM. It induces a dose-dependent reduction in the viability of PTEN-deficient prostate cancer cells.
    Fórmula:C33H52N6O3
    Cor e Forma:Solid
    Peso molecular:580.8

    Ref: TM-T203332

    10mg
    A consultar
    50mg
    A consultar
  • MAK683-CH2CH2COOH hydrochloride


    MAK683-CH2CH2COOH, an EED binder, was key in crafting PROTAC EED degrader-1 and -2 targeting VHL-E3 ligase.
    Fórmula:C23H22ClFN6O3
    Cor e Forma:Solid
    Peso molecular:484.91

    Ref: TM-T73945

    5mg
    A consultar
    50mg
    A consultar
  • (rel)-Tranylcypromine D5 hydrochloride

    CAS:
    (rel)-Tranylcypromine D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride.
    Fórmula:C9H12ClN
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:174.682

    Ref: TM-T12701

    100mg
    A consultar
    500mg
    A consultar
  • SJ46420


    SJ46420, a potent and selective precursor variant of SJ46421, functions as a BRD3 PROTAC degrader through a KLHDC2-dependent mechanism. This compound specifically degrades BRD3, which concurrently results in the partial reduction of BRD2 or BRD4 levels.
    Fórmula:C43H43ClN8O5S2
    Cor e Forma:Solid
    Peso molecular:851.44

    Ref: TM-T201117

    10mg
    A consultar
    50mg
    A consultar
  • mUNO

    CAS:
    mUNO is a tumor-homing peptide (mUNO, sequence: "CSPGAK") that specifically binds to murine CD206, targeting tumor-associated macrophages that express CD206/MRC1. Additionally, mUNO can interact with human recombinant CD206.
    Fórmula:C22H39N7O8S
    Cor e Forma:Solid
    Peso molecular:561.652

    Ref: TM-TP3071

    10mg
    A consultar
    50mg
    A consultar
  • MRS2698

    CAS:
    MRS2698: potent P2Y2 agonist, EC50 8 nM, >300x selectivity over P2Y4/P2Y6.
    Fórmula:C9H16N3O13P3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:499.22

    Ref: TM-T16139

    25mg
    A consultar
    50mg
    A consultar
    100mg
    A consultar
  • HDAC1/2-IN-3

    CAS:
    HDAC1/2-IN-3 is an inhibitor of both HDAC1 and HDAC2, demonstrating IC50 values of 0-5 nM and 5-10 nM, respectively.
    Fórmula:C24H25N5OS
    Cor e Forma:Solid
    Peso molecular:431.56

    Ref: TM-T39567

    5mg
    873,00€
  • TYK2 activator-1


    TYK2activator-1 (16b) is a TYK2 activator with an EC50 value of 1.78 μM. It inhibits JAK2 and JAK3 with IC50 values of 6.8 μM and 6.3 μM, respectively.
    Fórmula:C23H21FN4O2
    Cor e Forma:Solid
    Peso molecular:404.16485

    Ref: TM-T207637

    10mg
    A consultar
    50mg
    A consultar
  • UNC4976


    UNC4976 is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids.
    Fórmula:C47H70N6O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:847.09

    Ref: TM-T13255

    100mg
    A consultar
    500mg
    A consultar
  • HDAC/CD13-IN-1


    HDAC/CD13-IN-1 (Compound 12) is an inhibitor of both HDAC and CD13, with IC50 values of 0.34 μM for hCD13, 0.53 μM for porcine CD13, and 0.03, 0.06, and 0.02 μM
    Fórmula:C27H41Cl2N5O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:570.55

    Ref: TM-T79683

    5mg
    A consultar
    50mg
    A consultar
  • Flindersine

    CAS:
    Flindersine is a useful organic compound for research related to life sciences. The catalog number is T124718 and the CAS number is 523-64-8.
    Fórmula:C14H13NO2
    Cor e Forma:Solid
    Peso molecular:227.263

    Ref: TM-T124718

    1mg
    A consultar
    5mg
    A consultar