Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2441 produtos de "Cromatina/Epigenética"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
CP 46665
CAS:CP 46665 is a bio-active chemical.Fórmula:C35H66Cl2N2O2Cor e Forma:SolidPeso molecular:617.82BRD9 Degrader-1
<p>BRD9 Degrader-1 functions as a BRD9 degrader, demonstrating micromolar binding affinity towards BRD9 and nanomolar affinity for the ternary complex involving</p>Pureza:98%Cor e Forma:Odour SolidMS9715
MS9715 is a potent and selective NSD3-targeting PROTAC, designed by leveraging BI-9321, which targets the PWWP1 domain of NSD3, in conjunction with an E3 ligaseFórmula:C58H74FN9O5SPureza:98%Cor e Forma:SolidPeso molecular:1028.33Cath-L-dBET1
Cath-L-dBET1 is a PROTAC degrader targeting BRD4. It has an IC50 value of 2.8 μM in MDA-MB-231 cells. Activated by cathepsin L (Cath-L), Cath-L-dBET1 recruits E3 ubiquitin ligase to degrade BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable for antitumor research.Cor e Forma:Odour SolidBET-IN-17
<p>BET-IN-17, also known as compound 16, serves as a pan-inhibitor for BET, exhibiting inhibitory potencies (pIC50) of 7.8 for BET BD1 and 7.6 for BET BD2 [1].</p>Fórmula:C30H36N4O2Pureza:98%Cor e Forma:SolidPeso molecular:484.63MC4171
MC4171 is a selective KAT8 inhibitor with antiproliferative activity and can be used to study cancer.Fórmula:C21H15N3O3Pureza:99.56%Cor e Forma:SolidPeso molecular:357.36PCAF-IN-1
CAS:PCAF-IN-1 is a highly selective PCAF inhibitor with potential anti-tumor, anti-inflammatory, and anti-heart disease effects.Fórmula:C15H11ClN6Cor e Forma:SolidPeso molecular:310.74KDM4C-IN-1
CAS:KDM4C-IN-1 is aKDM4C inhibitor withial anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.Fórmula:C15H14N4O3Pureza:99.33%Cor e Forma:SolidPeso molecular:298.3GSK778
CAS:GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.Fórmula:C30H33N5O3Pureza:98.42%Cor e Forma:SolidPeso molecular:511.61Ref: TM-T9703
1mg160,00€5mg311,00€10mg502,00€25mg1.008,00€50mg1.596,00€100mg2.213,00€1mL*10mM (DMSO)47,00€TPOP146
CAS:TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).Fórmula:C27H35N3O5Pureza:98%Cor e Forma:SolidPeso molecular:481.58DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Fórmula:C26H35N7O5Cor e Forma:SolidPeso molecular:525.6T-448
CAS:T-448 is a lysine-specific demethylase 1 inhibitor (IC50: 22 nM) that improves learning function in mice.T-448 can be used to study memory deficits.Fórmula:C19H22N4O3SPureza:97% - 98.63%Cor e Forma:SolidPeso molecular:386.47GSK2879552
CAS:GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.Fórmula:C23H28N2O2Pureza:99.22%Cor e Forma:SolidPeso molecular:364.48AZ505 ditrifluoroacetate
CAS:AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).Fórmula:C33H40Cl2F6N4O8Cor e Forma:SolidPeso molecular:805.59KDM4-IN-3
CAS:KDM4-IN-3 is a KDM4 inhibitor that is cell-permeable and kills prostate cancer cells at low micromolar concentrations.Fórmula:C17H14N4OCor e Forma:SolidPeso molecular:290.32(2R)-Octyl-α-hydroxyglutarate
CAS:(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.Fórmula:C13H24O5Cor e Forma:SolidPeso molecular:260.33AS-85
CAS:AS-85 is an ASH1L inhibitor with anti-leukemic activity that inhibits leukemic cell growth and increases cLogP.Fórmula:C26H28F3N5O3S2Pureza:98.96%Cor e Forma:SolidPeso molecular:579.66SGC-iMLLT
CAS:SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular targetFórmula:C22H24N6OPureza:99.21% - 99.92%Cor e Forma:SolidPeso molecular:388.47PROTAC EZH2 Degrader-1
CAS:PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.Fórmula:C54H67N7O8Cor e Forma:SolidPeso molecular:942.15Itacitinib adipate
CAS:Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.Fórmula:C32H33F4N9O5Cor e Forma:SolidPeso molecular:699.66
