Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2441 produtos de "Cromatina/Epigenética"
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Gintemetostat
CAS:Gintemetostat (KTX-1001) is a potent NSD2 inhibitor (IC50=0.001-0.01μM) for treating NSD2-dysregulated cancers.Fórmula:C25H26F4N8O2Cor e Forma:SolidPeso molecular:546.52INO-1001
CAS:INO-1001: potent PARP inhibitor with antitumor properties, enhances radiosensitivity & radiation-induced cell death.Fórmula:C23H25N3O4SCor e Forma:SolidPeso molecular:439.537-Chloro-4-(piperazin-1-yl)quinoline
CAS:7-Cl-4-(piperazin-1-yl)quinolone: sirtuin inhibitor, serotonin uptake blocker, antimalarial (D10 IC50 1.18µM, K1 IC50 0.97µM).Fórmula:C13H14ClN3Pureza:99.52%Cor e Forma:Light Yellow SolidPeso molecular:247.72AMI-1 free acid
CAS:<p>AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.</p>Fórmula:C21H16N2O9S2Pureza:97.8%Cor e Forma:SolidPeso molecular:504.49WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Fórmula:C17H14BrN3OPureza:98.92% - 99.73%Cor e Forma:SolidPeso molecular:356.22PJ34 hydrochloride
CAS:PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.Fórmula:C17H18ClN3O2Pureza:98.87% - ≥95%Cor e Forma:SolidPeso molecular:331.8NCGC00244536
CAS:NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).Fórmula:C25H22N2O2Pureza:97.2% - 99.72%Cor e Forma:SolidPeso molecular:382.45Ref: TM-TQ0050
1mg96,00€5mg279,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)240,00€TCS PIM-1 1
CAS:TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.Fórmula:C18H11BrN2O2Pureza:97% - 97.98%Cor e Forma:SolidPeso molecular:367.2Ref: TM-T2253
1mg35,00€5mg64,00€10mg88,00€25mg187,00€50mg284,00€100mg424,00€200mg612,00€1mL*10mM (DMSO)97,00€BI-7273
CAS:BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.Fórmula:C20H23N3O3Pureza:97.37% - 99.57%Cor e Forma:SolidPeso molecular:353.41Rucaparib monocamsylate
CAS:<p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>Fórmula:C29H34FN3O5SPureza:99.82%Cor e Forma:SolidPeso molecular:555.66PF-CBP1
CAS:PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).Fórmula:C29H36N4O3Pureza:99.45%Cor e Forma:SolidPeso molecular:488.62BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Fórmula:C28H38N6O2Pureza:98.58% - 99.64%Cor e Forma:SolidPeso molecular:490.64Ref: TM-T7697
1mg40,00€5mg85,00€10mg117,00€25mg207,00€50mg311,00€100mg472,00€200mg642,00€1mL*10mM (DMSO)131,00€PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Fórmula:C22H26N4O3Pureza:98.82%Cor e Forma:SolidPeso molecular:394.473-methyl-1,2-dihydroquinolin-2-one
CAS:3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.Fórmula:C10H9NOPureza:99.62%Cor e Forma:SolidPeso molecular:159.18Ref: TM-T50035
1mg38,00€5mg81,00€10mg108,00€25mg178,00€50mg264,00€100mg374,00€200mg507,00€1mL*10mM (DMSO)65,00€GSK-J1
CAS:GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.Fórmula:C22H23N5O2Pureza:99.23% - 99.67%Cor e Forma:SolidPeso molecular:389.45SAR-20347
CAS:SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).Fórmula:C21H18ClFN4O4Pureza:98.99% - 99.77%Cor e Forma:SolidPeso molecular:444.84Ref: TM-T4210
1mg35,00€5mg80,00€10mg116,00€25mg227,00€50mg354,00€100mg588,00€200mg818,00€1mL*10mM (DMSO)88,00€Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Fórmula:C21H18F3N5OPureza:98.91%Cor e Forma:SolidPeso molecular:413.4Ref: TM-T5524
1mg70,00€2mg95,00€5mg160,00€10mg250,00€25mg424,00€50mg612,00€100mg842,00€200mg1.159,00€1mL*10mM (DMSO)170,00€HJ-PI01
CAS:<p>HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.</p>Fórmula:C14H11NO2Pureza:98.92%Cor e Forma:SolidPeso molecular:225.24NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Fórmula:C11H6N4O4SPureza:99.84%Cor e Forma:SolidPeso molecular:290.25Ref: TM-T6908
2mg35,00€5mg50,00€10mg66,00€25mg124,00€50mg188,00€100mg354,00€200mg495,00€1mL*10mM (DMSO)52,00€653-47
CAS:653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).Fórmula:C20H19ClN2O3Cor e Forma:SolidPeso molecular:370.83
