
Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2441 produtos de "Cromatina/Epigenética"
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ARN-3236
CAS:ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFórmula:C19H16N2O2SPureza:98.89% - 99.7%Cor e Forma:SolidPeso molecular:336.41Ref: TM-T5993
1mg60,00€5mg97,00€10mg160,00€25mg264,00€50mg354,00€100mg540,00€200mg777,00€1mL*10mM (DMSO)150,00€6-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).Fórmula:C9H9BrN2OPureza:99.28%Cor e Forma:SolidPeso molecular:241.08Ref: TM-T8609
1mg62,00€5mg123,00€10mg180,00€25mg298,00€50mg419,00€100mg567,00€200mg752,00€1mL*10mM (DMSO)113,00€Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Fórmula:C51H82O21Pureza:99.51% - 99.63%Cor e Forma:SolidPeso molecular:1031.18UNC1079
CAS:<p>UNC1079 is an selective L3MBTL3 domain inhibitor</p>Fórmula:C28H42N4O2Pureza:99.48%Cor e Forma:SolidPeso molecular:466.66Senaparib
CAS:Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.Fórmula:C24H20F2N6O3Pureza:99.8%Cor e Forma:SolidPeso molecular:478.45Ref: TM-T9593
1mg46,00€2mg59,00€5mg87,00€10mg153,00€25mg274,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)96,00€Senaparib hydrochloride
CAS:Senaparib hydrochloride is a potent and selective oral PARP1/2 inhibitor with strong antitumor activity.Fórmula:C24H21ClF2N6O3Cor e Forma:SolidPeso molecular:514.92NCGC00244536
CAS:NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).Fórmula:C25H22N2O2Pureza:97.2% - 99.72%Cor e Forma:SolidPeso molecular:382.45Ref: TM-TQ0050
1mg96,00€5mg279,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)240,00€KDM4D-IN-1
CAS:KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).Fórmula:C11H7N5OPureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:225.21Ref: TM-T4214
1mg77,00€5mg166,00€10mg259,00€25mg522,00€50mg838,00€100mg1.225,00€1mL*10mM (DMSO)177,00€Glucosamine sulfate
CAS:Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.Fórmula:C6H13NO5·H2SO4Pureza:99.64%Cor e Forma:White CrystalPeso molecular:277.25EPZ015666
CAS:EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity.Fórmula:C20H25N5O3Pureza:98% - 99.64%Cor e Forma:SolidPeso molecular:383.44SAR-20347
CAS:SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).Fórmula:C21H18ClFN4O4Pureza:98.99% - 99.77%Cor e Forma:SolidPeso molecular:444.84Ref: TM-T4210
1mg35,00€5mg80,00€10mg116,00€25mg227,00€50mg354,00€100mg588,00€200mg818,00€1mL*10mM (DMSO)88,00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Cor e Forma:SolidPeso molecular:419.48GSK-J1
CAS:GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.Fórmula:C22H23N5O2Pureza:99.23% - 99.67%Cor e Forma:SolidPeso molecular:389.45LLY-507
CAS:LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.Fórmula:C36H42N6OPureza:99.58% - 99.93%Cor e Forma:SolidPeso molecular:574.76Ref: TM-T6879
1mg44,00€2mg55,00€5mg85,00€10mg138,00€25mg304,00€50mg552,00€100mg787,00€1mL*10mM (DMSO)110,00€PJ34 hydrochloride
CAS:PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.Fórmula:C17H18ClN3O2Pureza:98.87% - ≥95%Cor e Forma:SolidPeso molecular:331.8Lomeguatrib
CAS:Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .Fórmula:C10H8BrN5OSPureza:99.26% - >99.99%Cor e Forma:SolidPeso molecular:326.17JNJ-42041935
CAS:JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.Fórmula:C12H6ClF3N4O3Pureza:99.58% - ≥95%Cor e Forma:SolidPeso molecular:346.65Ref: TM-T3180
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg210,00€50mg354,00€100mg567,00€500mg1.198,00€1mL*10mM (DMSO)87,00€UPF 1069
CAS:UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.Fórmula:C17H13NO3Pureza:98.80% - 99.88%Cor e Forma:SolidPeso molecular:279.293,6-Dihydroxyflavone
CAS:3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Fórmula:C15H10O4Pureza:99.92%Cor e Forma:SolidPeso molecular:254.244-amino-1,8-Naphthalimide
CAS:4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nMFórmula:C12H8N2O2Pureza:95.13%Cor e Forma:Yellow Solid PowderPeso molecular:212.2
