Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2440 produtos de "Cromatina/Epigenética"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ARN-3236
CAS:ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFórmula:C19H16N2O2SPureza:98.89% - 99.7%Cor e Forma:SolidPeso molecular:336.41Ref: TM-T5993
1mg60,00€5mg97,00€10mg160,00€25mg264,00€50mg354,00€100mg540,00€200mg777,00€1mL*10mM (DMSO)150,00€HNHA
CAS:HNHA is an inhibitor of HDAC.Fórmula:C17H21NO2SPureza:98.04%Cor e Forma:SolidPeso molecular:303.42Ref: TM-T21806
1mg44,00€5mg84,00€10mg135,00€25mg279,00€50mg445,00€100mg640,00€200mg879,00€1mL*10mM (DMSO)90,00€IOX2
CAS:IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.Fórmula:C19H16N2O5Pureza:98% - 99.59%Cor e Forma:SolidPeso molecular:352.34URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Fórmula:C27H27N5Pureza:99.32% - 99.98%Cor e Forma:SolidPeso molecular:421.544-Phenylbutyric acid
CAS:4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.Fórmula:C10H12O2Pureza:98.40% - 99.76%Cor e Forma:SolidPeso molecular:164.2Eicosapentaenoic Acid sodium
CAS:EPA sodium, an oral omega-3, demethylates DNA, reactivates tumor suppressors, and induces vasodilation.Fórmula:C20H29NaO2Cor e Forma:SolidPeso molecular:324.43TIQ-A
CAS:TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.Fórmula:C11H7NOSPureza:99.75%Cor e Forma:SolidPeso molecular:201.24Ref: TM-T50098
1mg50,00€5mg97,00€10mg170,00€25mg306,00€50mg437,00€100mg562,00€200mg777,00€1mL*10mM (DMSO)101,00€OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Fórmula:C25H27Cl2N5O2Cor e Forma:SolidPeso molecular:522.31SAR-20347
CAS:SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).Fórmula:C21H18ClFN4O4Pureza:98.99% - 99.77%Cor e Forma:SolidPeso molecular:444.84Ref: TM-T4210
1mg35,00€5mg80,00€10mg116,00€25mg227,00€50mg354,00€100mg588,00€200mg818,00€1mL*10mM (DMSO)88,00€4'-Methoxychalcone
CAS:4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.Fórmula:C16H14O2Pureza:99.86%Cor e Forma:SolidPeso molecular:238.28NCGC00244536
CAS:NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).Fórmula:C25H22N2O2Pureza:97.2% - 99.72%Cor e Forma:SolidPeso molecular:382.45Ref: TM-TQ0050
1mg96,00€5mg279,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)240,00€Perindopril
CAS:Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.Fórmula:C19H32N2O5Cor e Forma:White PowderPeso molecular:368.47Lomeguatrib
CAS:Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .Fórmula:C10H8BrN5OSPureza:99.26% - >99.99%Cor e Forma:SolidPeso molecular:326.17FG-2216
CAS:FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.Fórmula:C12H9ClN2O4Pureza:97.1% - >99.99%Cor e Forma:SolidPeso molecular:280.66TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Fórmula:C26H35N7O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:509.67GSK-J1
CAS:GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.Fórmula:C22H23N5O2Pureza:99.23% - 99.67%Cor e Forma:SolidPeso molecular:389.45BMS-P5
CAS:BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.Fórmula:C27H33ClN6O2Pureza:99.88%Cor e Forma:SolidPeso molecular:509.04Ref: TM-T22277
2mg47,00€5mg90,00€10mg143,00€25mg283,00€50mg505,00€100mg802,00€200mg1.074,00€1mL*10mM (DMSO)92,00€GSK-J4 Hydrochloride
CAS:GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Fórmula:C24H28ClN5O2Pureza:97.95% - 98.23%Cor e Forma:SolidPeso molecular:453.97Ref: TM-T4383
1mg40,00€2mg52,00€5mg88,00€10mg127,00€25mg217,00€50mg363,00€100mg533,00€200mg745,00€1mL*10mM (DMSO)139,00€PJ34 hydrochloride
CAS:PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.Fórmula:C17H18ClN3O2Pureza:98.87% - ≥95%Cor e Forma:SolidPeso molecular:331.8VX-11e
CAS:VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Fórmula:C24H20Cl2FN5O2Pureza:98.92% - ≥98%Cor e Forma:SolidPeso molecular:500.35
