Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2437 produtos de "Cromatina/Epigenética"
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GSK2801
CAS:GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.Fórmula:C20H21NO4SPureza:97.78% - 99.45%Cor e Forma:SolidPeso molecular:371.455-Methyl-2'-deoxycytidine
CAS:5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.Fórmula:C10H15N3O4Pureza:99.18% - 99.69%Cor e Forma:SolidPeso molecular:241.242-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one
CAS:2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.Fórmula:C10H11NOSPureza:99.68%Cor e Forma:SolidPeso molecular:193.275-Fluoro-2'-deoxycytidine
CAS:5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .Fórmula:C9H12FN3O4Pureza:97.91%Cor e Forma:Fine White PowderPeso molecular:245.21A-366
CAS:A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.Fórmula:C19H27N3O2Pureza:97.28% - 99.8%Cor e Forma:SolidPeso molecular:329.44UNC3866 TFA(1872382-47-2 free base)
CAS:UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Fórmula:C45H67F3N6O10Pureza:98.43%Cor e Forma:SolidPeso molecular:909.046-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Fórmula:C5H5N5SPureza:98.75% - >99.99%Cor e Forma:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecular:167.19IOX4
CAS:IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)Fórmula:C15H16N6O3Pureza:99.97%Cor e Forma:SolidPeso molecular:328.33NEO2734
CAS:NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).Fórmula:C22H24F3N3O3Pureza:98.72% - 98.8%Cor e Forma:SolidPeso molecular:435.44GSK343
CAS:GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFórmula:C31H39N7O2Pureza:98% - 99.9%Cor e Forma:SolidPeso molecular:541.69Panaxadiol
CAS:Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Fórmula:C30H52O3Pureza:98% - 99.9%Cor e Forma:SolidPeso molecular:460.73XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Fórmula:C22H31N9OPureza:99.07%Cor e Forma:SolidPeso molecular:437.54Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Fórmula:C23H28N8OSPureza:99.99%Cor e Forma:SolidPeso molecular:464.591-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS:1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).Fórmula:C17H19NOPureza:99.08%Cor e Forma:SolidPeso molecular:253.34GSK620
CAS:<p>GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.</p>Fórmula:C18H19N3O3Pureza:99.42% - 99.88%Cor e Forma:SolidPeso molecular:325.36Talazoparib
CAS:Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).Fórmula:C19H14F2N6OPureza:97.02% - 99.92%Cor e Forma:SolidPeso molecular:380.35Solcitinib
CAS:<p>Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.</p>Fórmula:C22H23N5O2Pureza:99.61% - 99.82%Cor e Forma:SolidPeso molecular:389.45Dbet57
CAS:dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.Fórmula:C34H31ClN8O5SPureza:99.36% - 99.52%Cor e Forma:SolidPeso molecular:699.18MAT2A inhibitor 4
CAS:MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancerFórmula:C16H15ClFNPureza:99.17%Cor e Forma:SolidPeso molecular:275.75Mivebresib
CAS:Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.Fórmula:C22H19F2N3O4SPureza:98.74% - 99.32%Cor e Forma:SolidPeso molecular:459.47
