Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2440 produtos de "Cromatina/Epigenética"
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AdipoR agonist 1
CAS:AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.Fórmula:C26H35N3O3Cor e Forma:SolidPeso molecular:437.57BG47
CAS:BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.Fórmula:C25H22N4O2SCor e Forma:SolidPeso molecular:442.54I-BET787
CAS:I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.Fórmula:C16H20ClN3O2Cor e Forma:SolidPeso molecular:321.80KAT6-IN-1
CAS:KAT6-IN-1 (compound E) is a selective, orally available inhibitor of histone acetyltransferases KAT6A and KAT6B, exhibiting antitumour activity for cancer.Fórmula:C19H18N4O5SPureza:99.86%Cor e Forma:SolidPeso molecular:414.43CrBKA
CAS:CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .Fórmula:C28H31N3O6Cor e Forma:SolidPeso molecular:505.56(3S,4S)-Tofacitinib
CAS:(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.Fórmula:C16H20N6OPureza:98%Cor e Forma:SolidPeso molecular:312.37BG48
CAS:BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.Fórmula:C25H23N5OSCor e Forma:SolidPeso molecular:441.55HDAC6-IN-27
CAS:HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].Fórmula:C15H15N3O4Cor e Forma:SolidPeso molecular:301.3MY-1B
CAS:MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.Fórmula:C22H18BrN3O2Pureza:99.81% - >99.99%Cor e Forma:SoildPeso molecular:436.3E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Fórmula:C21H30O6Pureza:99.52%Cor e Forma:SolidPeso molecular:378.46GW843682X
CAS:GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Fórmula:C22H18F3N3O4SPureza:99.92%Cor e Forma:SolidPeso molecular:477.46UNC0224
CAS:UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.Fórmula:C26H43N7O2Pureza:99.80%Cor e Forma:SolidPeso molecular:485.67Ref: TM-T17203
1mg51,00€2mg73,00€5mg97,00€10mg159,00€25mg354,00€50mg558,00€100mg797,00€500mg1.634,00€1mL*10mM (DMSO)107,00€TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Fórmula:C26H25ClF3N5O3Pureza:99.73%Cor e Forma:SolidPeso molecular:547.96Ref: TM-T6039
1mg38,00€5mg80,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)96,00€GSK-1268997
CAS:GSK-1268997 is a bio-active chemical.Fórmula:C21H23N7O3SPureza:99.33% - 99.81%Cor e Forma:SolidPeso molecular:453.52TMPA
CAS:TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.Fórmula:C21H32O6Pureza:99.21%Cor e Forma:SolidPeso molecular:380.48Ref: TM-T13173
1mg80,00€5mg167,00€10mg274,00€25mg465,00€50mg655,00€100mg1.017,00€1mL*10mM (DMSO)170,00€KF 13218
CAS:KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.Fórmula:C20H20N2O3Pureza:98%Cor e Forma:SolidPeso molecular:336.38JAK-IN-20
CAS:JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.Fórmula:C28H30FN7O2Cor e Forma:SolidPeso molecular:515.58HAT-IN-1
CAS:HAT-IN-1 is an inhibitor of HAT used in the research of cancer.Fórmula:C23H18BrF4N3O4Pureza:98%Cor e Forma:SolidPeso molecular:556.3BRM/BRG1 ATP Inhibitor-4
CAS:BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders.Fórmula:C25H32N6O3SCor e Forma:SolidPeso molecular:496.62Piribedil dihydrochloride
CAS:dopamine agonistFórmula:C16H20Cl2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:371.26
