Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2476 produtos de "Cromatina/Epigenética"
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CBP/p300-IN-10
CAS:CBP/p300-IN-10, potent EP300/CREBBP inhibitor; IC50: 26 nM/39 nM. Potential for cancer research.Fórmula:C25H24F5N5O3Cor e Forma:SolidPeso molecular:537.48DCE_254
CAS:DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Fórmula:C21H17N9OSPureza:98%Cor e Forma:SolidPeso molecular:443.48Langkamide
CAS:Langkamide is a HIF-2 inhibitor with EC₅₀ values of 14.0 uM.Fórmula:C16H17NO5Pureza:98%Cor e Forma:SolidPeso molecular:303.31SGC6870
CAS:SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.Fórmula:C23H21BrN2O2SCor e Forma:SolidPeso molecular:469.39BF1
CAS:BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.Fórmula:C12H12ClN3SCor e Forma:SolidPeso molecular:265.76Farnesylthiotriazole
CAS:Farnesylthiotriazole is a persistent PKC activator agent.Fórmula:C17H27N3SPureza:98%Cor e Forma:SolidPeso molecular:305.48Tenovin-D3
CAS:Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.Fórmula:C22H27Cl3N4O3SPureza:98%Cor e Forma:SolidPeso molecular:533.9ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Fórmula:C27H28FN3O2Pureza:97.84% - 98.20%Cor e Forma:SolidPeso molecular:445.53Ref: TM-T24484
1mgA consultar5mg730,00€10mgA consultar25mg1.539,00€50mg1.941,00€100mg2.451,00€150mg2.565,00€PF-00956980
CAS:PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.Fórmula:C18H26N6OCor e Forma:SolidPeso molecular:342.44HIF-IN-33
CAS:HIF-IN-33 is an inhibitor of HIF pathway.Fórmula:C21H17F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:414.38NVS-BET-1
CAS:NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.Fórmula:C22H21ClN4O2Cor e Forma:SolidPeso molecular:408.88ZLD2218
CAS:ZLD2218, a potent inhibitor of BRD4 with an IC50 value of 107 nM, has been demonstrated to mitigate kidney injury and fibrosis through extensive studies.Fórmula:C22H18N4OCor e Forma:SolidPeso molecular:354.4BET-BAY 002
CAS:BET-BAY 002 is an effective BET bromodomain inhibitor demonstrating efficacy in vivo and in vitro against multiple myeloma and leukaemia models.Fórmula:C22H18ClN5OCor e Forma:SolidPeso molecular:403.86Fagaronine chloride
CAS:Fagaronine chloride is a potent inhibitor of Topoisomerases I.Fórmula:C21H20ClNO4Cor e Forma:SolidPeso molecular:385.84DCE_42
CAS:DCE_42 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Fórmula:C22H19N9O2SPureza:98%Cor e Forma:SolidPeso molecular:473.51Lobelane Hydrochloride
CAS:Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.Fórmula:C22H30ClNCor e Forma:SolidPeso molecular:343.93HDAC/CK2-IN-1
CAS:HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Fórmula:C15H18Br4N4O2Cor e Forma:SolidPeso molecular:605.951,2-Didecanoylglycerol
CAS:1,2-Didecanoylglycerol has functions as bioregulator of protein kinase C in human platelets.Fórmula:C23H44O5Cor e Forma:SolidPeso molecular:400.59SirReal-1
CAS:SirReal-1 is an effective and selective inhibitor of Sirt2.Fórmula:C18H18N4OS2Pureza:98%Cor e Forma:SolidPeso molecular:370.49Prospasmine
CAS:Prospasmine is an anticholinergic.Fórmula:C17H28ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:313.87
