Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2490 produtos de "Cromatina/Epigenética"
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PU141
CAS:PU141 is a novel inhibitor of histone acetyltransferase (HAT).Fórmula:C14H9F3N2OSPureza:98%Cor e Forma:SolidPeso molecular:310.29SRTCX1002
CAS:SRTCX1002 is a SIRT1 Activator Suppressing Inflammatory Responses through Promotion of p65 Deacetylation and NF-κB Activity inhibitor.Fórmula:C21H19N5O2SPureza:98%Cor e Forma:SolidPeso molecular:405.47LSD1-IN-12
CAS:LSD1-IN-12 (compound 2) is an effective inhibitor of LSD1, demonstrating inhibitory Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-BFórmula:C16H16N2OCor e Forma:SolidPeso molecular:252.31Bisindolylmaleimide II
CAS:protein kinase C (PKC) inhibitorFórmula:C27H26N4O2Pureza:98%Cor e Forma:SolidPeso molecular:438.52HIF-1α inhibitor-1
CAS:HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor.Fórmula:C15H11N3O4Cor e Forma:SolidPeso molecular:297.27OICR-0547
CAS:OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.Fórmula:C28H29F3N4O4Pureza:98%Cor e Forma:SolidPeso molecular:542.55DC-CPin7
CAS:DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].Fórmula:C19H22N2O5Cor e Forma:SolidPeso molecular:358.39YF479
CAS:YF479 is an inhibitor of histone deacetylase that acts by inhibiting breast tumor growth, metastasis, and recurrence.Fórmula:C22H27BrN2O5Pureza:98%Cor e Forma:SolidPeso molecular:479.36CD161
CAS:CD161: powerful, selective oral BET inhibitor; IC50: 28.2 nM (BRD4 BD1), 7.2 nM (BRD4 BD2); strong anticancer properties.Fórmula:C26H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:435.48PKC-IN-4
CAS:PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM.Fórmula:C21H25N5SCor e Forma:SolidPeso molecular:379.52SB-284851-BT
CAS:SB-284851-BT: BRD4/p38α/BRDT inhibitor; IC50: BRD4-BD1 1.7µM, BRDT 18µM, BRD4 3.7µM; Kd p38α 0.47nM; reduces IL-8, affects c-Myc/NF-κB.Fórmula:C26H26FN5OCor e Forma:SolidPeso molecular:443.522′-Deoxy-5-nitrocytidine
CAS:2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].Fórmula:C9H12N4O6Cor e Forma:SolidPeso molecular:272.21Sirt1/2-IN-1
CAS:Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.Fórmula:C22H13ClN2OS2Cor e Forma:SolidPeso molecular:420.93HDAC-IN-49
HDAC-IN-49: potent, broad HDAC inhibitor; IC50s: 10-1880 nM for HDAC1-6; strong anti-leukemic, low toxicity to healthy cells.Fórmula:C26H27FN4O4Cor e Forma:SolidPeso molecular:478.52IDO1 and HDAC1 Inhibitor
CAS:IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM).Fórmula:C25H22BrFN8O4Pureza:98%Cor e Forma:SolidPeso molecular:597.4JAK-IN-14
CAS:JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.Fórmula:C19H15FN4OPureza:98.27%Cor e Forma:SolidPeso molecular:334.35Ref: TM-T9764
1mg86,00€5mg180,00€10mg283,00€25mg587,00€50mg938,00€100mg1.491,00€200mg1.985,00€1mL*10mM (DMSO)188,00€RM65
CAS:RM65 is an arginine methyltransferase inhibitor.Fórmula:C34H32N2O4S2Pureza:98%Cor e Forma:SolidPeso molecular:596.76MDK8228
CAS:MDK8228 is an inhibitor of CBP/p300 and BRD4 bromodomain. MDK8228 downregulates IL-6, IL-ß and IFN-ß in macrophages.Fórmula:C31H41N5O3Cor e Forma:SolidPeso molecular:531.69EP009
CAS:EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies.Fórmula:C14H24O2Cor e Forma:SolidPeso molecular:224.34YM-53601 free base
CAS:YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.Fórmula:C21H21FN2OPureza:98%Cor e Forma:SolidPeso molecular:336.4
