Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2547 produtos de "Cromatina/Epigenética"
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BiBET
CAS:BiBET is a potent, selective, bivalent inhibitor of BET bromodomains.Fórmula:C26H30N10O3Cor e Forma:SolidPeso molecular:530.58MS453
CAS:MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.Fórmula:C20H27N5O3Cor e Forma:SolidPeso molecular:385.46HDAC-IN-30
CAS:HDAC-IN-30 is a potent HDAC inhibitor targeting HDAC1, 2, 3, 6, and 8 with strong antitumor efficacy.
Fórmula:C22H23N5O3Cor e Forma:SolidPeso molecular:405.45JAK3-IN-1
CAS:JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Fórmula:C26H30ClN7O2Cor e Forma:SolidPeso molecular:508.02CK2/PIM1-IN-1
CAS:CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.Fórmula:C15H9NO4S2Pureza:98%Cor e Forma:SolidPeso molecular:331.37EZH2-IN-3
CAS:EZH2-IN-3 is an inhibitor of EZH2 and EZH1 with selective impact on diffuse large B cell lymphoma cell growth.Fórmula:C27H28ClN5O2Pureza:98%Cor e Forma:SolidPeso molecular:490KDM2/7-IN-1
CAS:KDM2/7-IN-1 is a selective histone demethylase inhibitor (IC50s: 0.2–>120 μM) that inhibits HeLa and KYSE-150 cell proliferation, epigenetic and cancer.Fórmula:C15H27NO4Pureza:99.87%Cor e Forma:SolidPeso molecular:285.38BRM/BRG1 ATP Inhibitor-4
CAS:BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders.Fórmula:C25H32N6O3SCor e Forma:SolidPeso molecular:496.62DPQ
CAS:DPQ inhibits PARP-1, aids in neuroprotection, restores ATP, and lessens neuronal injury from NMDA.
Fórmula:C18H26N2O2Pureza:98%Cor e Forma:SolidPeso molecular:302.41FAK/aurora kinase-IN-1
CAS:FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Fórmula:C23H24ClN7O3Cor e Forma:SolidPeso molecular:481.93JNJ-7925476 free base
CAS:JNJ-7925476 is an TRI antidepressant agent.Fórmula:C20H19NPureza:98%Cor e Forma:SolidPeso molecular:273.37K00135
CAS:K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.Fórmula:C18H18N4OPureza:98.16%Cor e Forma:SolidPeso molecular:306.36SHP2/HDAC-IN-1
CAS:SHP2/HDAC-IN-1: dual SHP2/HDAC inhibitor, IC50: 20.4 nM/25.3 nM, boosts antitumor immunity, aids cancer immunotherapy research.Fórmula:C34H35Cl2N7O3Cor e Forma:SolidPeso molecular:660.59G9a-IN-2
CAS:G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).Fórmula:C30H42N4O4Cor e Forma:SolidPeso molecular:522.68J1075
CAS:J1075 is an histone deacetylase 8 (HDAC8) inhibitor.Fórmula:C9H6ClNO2SPureza:98%Cor e Forma:SolidPeso molecular:227.67S-Aristeromycinylhomocysteine
CAS:S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.Fórmula:C15H22N6O4SCor e Forma:SolidPeso molecular:382.44(R)-OR-S1
CAS:(R)-OR-S1 is a SAM-competitive, highly selective, orally bioavailable dual inhibitor of EZH1/2.Fórmula:C26H34BrN3O4Pureza:98%Cor e Forma:SolidPeso molecular:532.475-Aza-4'-thio-2'-deoxycytidine
CAS:5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].Fórmula:C8H12N4O3SCor e Forma:SolidPeso molecular:244.27ZLD10A
CAS:ZLD10A is a highly potent and selective small molecule inhibitor of EZH2.Fórmula:C37H48N4O4Pureza:98%Cor e Forma:SolidPeso molecular:612.8WAY-260022
CAS:WAY-260022 is the norepinephrine transporter inhibitor.Fórmula:C21H31F3N2O2Pureza:97.61% - 99.41%Cor e Forma:SolidPeso molecular:400.48
