Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2573 produtos de "Cromatina/Epigenética"
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BF1
CAS:BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.Fórmula:C12H12ClN3SCor e Forma:SolidPeso molecular:265.76TM6089
CAS:TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.Fórmula:C13H14N4O3SPureza:99.70%Cor e Forma:SolidPeso molecular:306.34Ref: TM-T17105
1mg52,00€5mg115,00€10mg167,00€25mg301,00€50mg452,00€100mg658,00€200mg884,00€1mL*10mM (DMSO)123,00€ARTD10/PARP10-IN-1
CAS:ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.Fórmula:C12H12N2O4Pureza:99.14%Cor e Forma:SolidPeso molecular:248.23LP99
CAS:LP99 is an epigenetic probe.Fórmula:C26H30ClN3O4SPureza:99.74%Cor e Forma:SolidPeso molecular:516.05Ref: TM-T15784
1mg43,00€5mg96,00€10mg145,00€25mg305,00€50mg442,00€100mgA consultar1mL*10mM (DMSO)97,00€CM-579
CAS:CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.Fórmula:C29H40N4O3Pureza:99.23%Cor e Forma:SolidPeso molecular:492.65Ref: TM-T10840L
1mg52,00€5mg90,00€10mg131,00€25mg207,00€50mg303,00€100mg447,00€1mL*10mM (DMSO)117,00€Tripolin A
CAS:Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)Fórmula:C15H11NO3Pureza:98%Cor e Forma:SolidPeso molecular:253.25PB131
CAS:PB131, a selective and brain-permeable HDAC6 inhibitor, exhibits high binding affinity (IC50: 1.8 nM) and potent anti-inflammatory activity, making it suitableFórmula:C16H16FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:301.32LW479
CAS:LW479 is a novel inhibitor of HDAC and is a promising candidate for the prevention of breast cancer.Fórmula:C21H23BrN2O4SCor e Forma:SolidPeso molecular:479.39MPT0G211
CAS:MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for Alzheimer's.Fórmula:C17H15N3O2Pureza:99.93% - 99.98%Cor e Forma:SolidPeso molecular:293.32Ref: TM-T60616
1mg92,00€5mg222,00€10mg356,00€25mg560,00€50mg782,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)245,00€Farnesylthiotriazole
CAS:Farnesylthiotriazole is a persistent PKC activator agent.Fórmula:C17H27N3SPureza:98%Cor e Forma:SolidPeso molecular:305.48LSD1-IN-5
CAS:LSD1-IN-5, a reversible LSD1 inhibitor, boosts H3K4me2 without affecting LSD1 expression; IC50: 121 nM.Fórmula:C15H13BrN2O3Pureza:98%Cor e Forma:SolidPeso molecular:349.18Exifone
CAS:Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increasedFórmula:C13H10O7Pureza:99.77% - 99.95%Cor e Forma:Yellow SolidPeso molecular:278.21GS-626510
CAS:GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).Fórmula:C25H22N4OCor e Forma:SolidPeso molecular:394.47DC_C66
CAS:DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.Fórmula:C28H22NO2Pureza:98%Cor e Forma:SolidPeso molecular:404.48SIRT1-IN-3
CAS:SIRT1-IN-3 (compound 3j) is a potent and selective inhibitor of silent information regulator 1 (SIRT1) with an IC 50 of 4.2 μM [1].Fórmula:C13H15BrN2OCor e Forma:SolidPeso molecular:295.17Tyk2-IN-7
CAS:Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).Fórmula:C18H15D3N6O3SPureza:98%Cor e Forma:SolidPeso molecular:401.46ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Fórmula:C27H28FN3O2Pureza:97.84% - 98.20%Cor e Forma:SolidPeso molecular:445.53ZLD1039
CAS:ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.Fórmula:C36H48N6O3Pureza:99.5%Cor e Forma:SolidPeso molecular:612.8SGC6870
CAS:SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.Fórmula:C23H21BrN2O2SCor e Forma:SolidPeso molecular:469.39
