Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2588 produtos de "Cromatina/Epigenética"
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HDAC6-IN-5
CAS:HDAC6-IN-5 (11b), potent HDAC6 blocker, crosses BBB, IC50: 0.025μM, hinders Aβ1-42/AChE aggregation, boosts neurites, low toxicity.Fórmula:C20H14BrN3O2Cor e Forma:SolidPeso molecular:408.25HDAC6-IN-6
CAS:HDAC6-IN-6: Potent HDAC6 blocker, BBB-permeable, IC50: 0.025μM; inhibits AChE, Aβ 1-42 aggregation; promotes neurite growth, low neurotoxicity.Fórmula:C20H15N3O2Cor e Forma:SolidPeso molecular:329.35AMPK activator 1
CAS:AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).Fórmula:C32H33F3N4O3Pureza:98%Cor e Forma:SolidPeso molecular:578.62CTPB
CAS:CTPB is a potent p300 histone acetyltransferase (HAT) activator that can be used in the preparation of hair growth promoters and/or hair loss treatments.Fórmula:C31H43ClF3NO2Pureza:99.51%Cor e Forma:SolidPeso molecular:554.13JAK3-IN-12
CAS:JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.Fórmula:C19H19N5O4SCor e Forma:SolidPeso molecular:413.45NV03
CAS:NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM) for cancer research. a ligand for E3 ligases in PROTAC synthesis.Fórmula:C19H27N5O2SPureza:99.88%Cor e Forma:SolidPeso molecular:389.52M122
CAS:M122 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.Fórmula:C24H25N5OS2Cor e Forma:SolidPeso molecular:463.62CTK7A
CAS:CTK7A is a water-soluble inhibitor of p300. CTK7A inhibits tumor growth in xenografted mice.Fórmula:C28H24N2NaO6Pureza:98%Cor e Forma:SolidPeso molecular:507.498MAT2A inhibitor 1
CAS:MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 < l00 nM).Fórmula:C31H22N6OSCor e Forma:SolidPeso molecular:526.61SB-429201
CAS:SB-429201 is an effective, selective inhibitor of HDAC1.Fórmula:C28H24N2O3Pureza:98%Cor e Forma:SolidPeso molecular:436.5JAK3-IN-9
CAS:JAK3-IN-9, potent JAK3 inhibitor, IC50 of 1.7 nM, highly selective, low toxicity, orally bioavailable, shows anti-arthritis activity.Fórmula:C17H23N5O4SCor e Forma:SolidPeso molecular:393.46LB-205
CAS:LB-205 is a Zn 2+ dependent pan-inhibitor of class I and class II HDACs. It also has a long half-life in vivo.Fórmula:C18H21N3O2SCor e Forma:SolidPeso molecular:343.44INCB16562
CAS:INCB16562: oral JAK1/2 inhibitor, halts IL-6/STAT3 in myeloma cells, boosts drug efficacy, stunts myeloma in mice.Fórmula:C19H11Cl2N5Cor e Forma:SolidPeso molecular:380.23Guadecitabine
CAS:Guadecitabine is a second-generation DNA methyltransferases inhibitor. It is used for research on acute myeloid leukemia and myelodysplastic syndromes.Fórmula:C18H24N9O10PPureza:98%Cor e Forma:SolidPeso molecular:557.41Bromodomain inhibitor-8
CAS:Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.Fórmula:C26H25ClN2O3Cor e Forma:SolidPeso molecular:448.94HDAC-IN-5
CAS:HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.Fórmula:C26H24F3N5O2SPureza:98%Cor e Forma:SolidPeso molecular:527.56CPI-455 HCl
CAS:CPI-455: specific KDM5A inhibitor, IC50=10±1nM, increases H3K4me3, reduces DTPs in cancer cells.Fórmula:C16H15ClN4OPureza:98%Cor e Forma:SolidPeso molecular:314.77ZL0454
CAS:ZL0454 is an effective and selective Bromodomain-containing protein 4 inhibitors (IC50: 49 and 32 nM for BD1 and BD2).Fórmula:C18H22N4O3SPureza:98%Cor e Forma:SolidPeso molecular:374.46Bromodomain inhibitor-9
CAS:Bromodomain inhibitor-9 selectively targets BRD4-1 (Kd 12 nM), used in metabolic, inflammatory, fibrotic, and autoimmune disease studies.Fórmula:C24H28N4O5SCor e Forma:SolidPeso molecular:484.571,2,3,4,5,6-Hexabromocyclohexane
CAS:Inhibits JAK2 autophosphorylation; non-cytotoxic at 100μM; 1μM reduces activity by 50%, 50μM nearly abolishes it.Fórmula:C6H6Br6Pureza:98%Cor e Forma:SolidPeso molecular:557.54
