Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2588 produtos de "Cromatina/Epigenética"
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Tankyrase-IN-2
CAS:Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectivelyFórmula:C17H14F2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:316.36(5H)-Phenanthridinone
CAS:6(5H)-Phenanthridinone suppresses PARP1/2, reduces RDM4 cell growth, downregulates pro-inflammatory genes, and alleviates EAE symptoms in rats.Fórmula:C13H9NOCor e Forma:SolidPeso molecular:195.22GNE-272
CAS:GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 μM for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300.Fórmula:C22H25FN6O2Cor e Forma:SolidPeso molecular:424.47MS-1020
CAS:MS-1020 inhibits JAK3/STAT3, blocks active JAK3, suppresses JAK3/STAT5 signaling, and targets STAT3 in certain cells.Fórmula:C21H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:346.38PB131
CAS:PB131, a selective and brain-permeable HDAC6 inhibitor, exhibits high binding affinity (IC50: 1.8 nM) and potent anti-inflammatory activity, making it suitableFórmula:C16H16FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:301.32SD-1029
CAS:SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.Fórmula:C25H32Br2Cl2N2O3Cor e Forma:SolidPeso molecular:639.25MPT0G211
CAS:MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for Alzheimer's.Fórmula:C17H15N3O2Pureza:99.93% - 99.98%Cor e Forma:SolidPeso molecular:293.32Ref: TM-T60616
1mg92,00€5mg222,00€10mg356,00€25mg560,00€50mg782,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)245,00€Jaspamycin
CAS:Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.Fórmula:C12H12N4O5Cor e Forma:SolidPeso molecular:292.25AC-93253 iodide
CAS:AC-93253 iodide is a selective inhibitor of SIRT2. It significantly enhances the acetylation of tubulin p53 and histone H4.Fórmula:C23H25IN2SPureza:98%Cor e Forma:SolidPeso molecular:488.43Ac-Lys-AMC
CAS:Ac-Lys-AMC (Hexanamide) is a fluorescent substrate for histone deacetylase HDACs.Fórmula:C18H23N3O4Pureza:98%Cor e Forma:SolidPeso molecular:345.39ZYJ-34v
CAS:ZYJ-34v is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.Fórmula:C27H35N3O6Pureza:98%Cor e Forma:SolidPeso molecular:497.58Exifone
CAS:Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increasedFórmula:C13H10O7Pureza:99.77% - 99.95%Cor e Forma:Yellow SolidPeso molecular:278.21(R)-UT-155
CAS:(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.Fórmula:C20H15F4N3O2Cor e Forma:SolidPeso molecular:405.35ARTD10/PARP10-IN-1
CAS:ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.Fórmula:C12H12N2O4Pureza:99.14%Cor e Forma:SolidPeso molecular:248.23PS315
CAS:PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.Fórmula:C23H19ClO2Pureza:98%Cor e Forma:SolidPeso molecular:362.85GS-626510
CAS:GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).Fórmula:C25H22N4OCor e Forma:SolidPeso molecular:394.47LW479
CAS:LW479 is a novel inhibitor of HDAC and is a promising candidate for the prevention of breast cancer.Fórmula:C21H23BrN2O4SCor e Forma:SolidPeso molecular:479.39KDM5A-IN-1
CAS:KDM5A-IN-1 is a pan-histidine lysine demethylase 5 KDM5 inhibitor that inhibits KDM5A, KDM5B, and KDM5C.Can be used in the study of cancer.Fórmula:C15H22N4O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:290.36
