Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2592 produtos de "Cromatina/Epigenética"
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G9a-IN-2
CAS:G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).Fórmula:C30H42N4O4Cor e Forma:SolidPeso molecular:522.68BRD4884
CAS:BRD4884 is a highly selective and efficient HDAC1 and HDAC2 inhibitor that also inhibits HDAC3, used in research on neurological disorders.Fórmula:C18H19FN2O2Pureza:99.19% - 99.21%Cor e Forma:SolidPeso molecular:314.35CPI703
CAS:CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.Fórmula:C17H22N4OPureza:98%Cor e Forma:SolidPeso molecular:298.385-Aza-4'-thio-2'-deoxycytidine
CAS:5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].Fórmula:C8H12N4O3SCor e Forma:SolidPeso molecular:244.27UNC2327
CAS:UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).Fórmula:C14H17N5O2SPureza:98%Cor e Forma:SolidPeso molecular:319.38Tripartin
CAS:Tripartin specifically inhibits the histone H3 lysine 9 demethylase KDM4 in HeLa cells.Fórmula:C10H8Cl2O4Cor e Forma:SolidPeso molecular:263.07CCT077791
CAS:CCT077791 is a potent inhibitor of p300 and PCAF histone acetyltransferase activity for cancer research.Fórmula:C9H5ClN2O3SPureza:98.60%Cor e Forma:SolidPeso molecular:256.67EZH2-IN-7
CAS:EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.Fórmula:C31H37D2N5O3SCor e Forma:SolidPeso molecular:563.75CPI-905
CAS:CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.Fórmula:C18H20N2O5Cor e Forma:SolidPeso molecular:344.36iBRD4-BD1
CAS:iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.Fórmula:C29H30F3N5OCor e Forma:SolidPeso molecular:521.58BAY1238097
CAS:BAY1238097 is a BET inhibitor with anticancer activity and antiproliferative activity for the study of advanced refractory malignancies.Fórmula:C25H33N5O3Pureza:98.1% - 98.79%Cor e Forma:SolidPeso molecular:451.56Ref: TM-T12660L
1mg49,00€5mg101,00€10mg172,00€25mg355,00€50mg620,00€100mg1.044,00€200mg1.404,00€1mL*10mM (DMSO)113,00€CMP-5 hydrochloride
CAS:CMP-5 hydrochloride: potent, selective PRMT5 inhibitor; inactive against PRMT1/4/7; blocks S2Me-H4R3 on histones.Fórmula:C21H22ClN3Pureza:98%Cor e Forma:SolidPeso molecular:351.87Dimethyl-bisphenol A
CAS:DMBPA inhibits HIF-1α, promotes its degradation by detaching Hsp90, and reduces Vegfa mRNA expression.Fórmula:C17H20O2Cor e Forma:SolidPeso molecular:256.34p32 Inhibitor M36
CAS:p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.Fórmula:C23H28N8O2Pureza:98%Cor e Forma:SolidPeso molecular:448.52KF 13218
CAS:KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.Fórmula:C20H20N2O3Pureza:98%Cor e Forma:SolidPeso molecular:336.38HDAC6-IN-46
CAS:HDAC6-IN-46 (compound 12) is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 6.2 nM. It is utilized in research related to Alzheimer's disease.Fórmula:C26H21N3O4Cor e Forma:SolidPeso molecular:439.46JNJ-9350
CAS:JNJ-9350: SMOX inhibitor (IC50 0.01 μM), PAO inhibitor (IC50 0.79 μM), for cancer research.Fórmula:C25H22N6OCor e Forma:SolidPeso molecular:422.48Sirtuin modulator 4
CAS:Sirtuin modulator 4 inhibits SIRT1 (EC50: 51-100 μM), may extend cell life and prevent diseases like diabetes and cancer.Fórmula:C18H10N2O2SCor e Forma:SolidPeso molecular:318.35aPKC-I
CAS:aPKC-I specifically inhibits PKCζ/i, blocks VEGF effects, and prevents IR-induced permeability in cells and live models.Fórmula:C15H17NO4SCor e Forma:SolidPeso molecular:307.36MC4343
MC4343, a potent dual inhibitor targeting both EZH2 and histone deacetylase, presents promising potential for cancer research applications.Fórmula:C36H41N5O4Cor e Forma:SolidPeso molecular:607.74
