Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2595 produtos de "Cromatina/Epigenética"
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HDAC6-IN-10
CAS:HDAC6-IN-10 is a potent HDAC6 inhibitor with 0.73 nM IC50, highly selective, and hinders multiple myeloma cell growth.Fórmula:C21H20N4O4Cor e Forma:SolidPeso molecular:392.41HMS607P03
CAS:HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway.Fórmula:C26H19ClN4O3S2Cor e Forma:SolidPeso molecular:535.04MAT2A-IN-4
CAS:MAT2A-IN-4 can be used for the cancer research that is an inhibitor of methionine adenosyltransferase 2A (MAT2A)[1].Fórmula:C18H16ClN3OCor e Forma:SolidPeso molecular:325.79MI-3
CAS:MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).Fórmula:C18H25N5S2Pureza:98.66% - 99.61%Cor e Forma:SolidPeso molecular:375.55GDC-4379
CAS:GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Fórmula:C21H18ClF2N7O3Cor e Forma:SolidPeso molecular:489.86Setin-1
CAS:Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.Fórmula:C29H21F3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:486.48Depudecin
CAS:Depudecin, a polyketide from Alternaria brassicicola, has an 11-carbon chain with two epoxides and six stereocenters, inhibits HDAC, and is anti-angiogenic.Fórmula:C11H16O4Cor e Forma:SolidPeso molecular:212.24PRMT5-IN-10
CAS:PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex.Fórmula:C13H17N5O4Cor e Forma:SolidPeso molecular:307.31Cercosporamide
CAS:Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.Fórmula:C16H13NO7Pureza:98%Cor e Forma:SolidPeso molecular:331.285-Octyl-α-ketoglutarate
CAS:In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes.Fórmula:C13H22O5Cor e Forma:SolidPeso molecular:258.31AMPK activator 6
CAS:AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.Fórmula:C25H28O5Cor e Forma:SolidPeso molecular:408.49HAT-IN-1
CAS:HAT-IN-1 is an inhibitor of HAT used in the research of cancer.Fórmula:C23H18BrF4N3O4Pureza:98%Cor e Forma:SolidPeso molecular:556.3GSK 525768A
CAS:GSK 525768A, the inactive enantiomer of GSK525762A, exhibits no activity towards BET.Fórmula:C22H22ClN5O2Cor e Forma:SolidPeso molecular:423.9Bizine dihydrochloride
CAS:Bizine dihydrochloride is a potent LSD1 inhibitor in vitro, being selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2.Fórmula:C18H25Cl2N3OCor e Forma:SolidPeso molecular:370.32OXFBD03
CAS:OXFBD03 is the bromodomain and extra terminal domain bromodomain family member BRD4(1) inhibitor.Fórmula:C20H19NO4Pureza:98%Cor e Forma:SolidPeso molecular:337.37CBP/p300-IN-10
CAS:CBP/p300-IN-10, potent EP300/CREBBP inhibitor; IC50: 26 nM/39 nM. Potential for cancer research.Fórmula:C25H24F5N5O3Cor e Forma:SolidPeso molecular:537.48PF-00956980
CAS:PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.Fórmula:C18H26N6OCor e Forma:SolidPeso molecular:342.44Furamidine
CAS:Furamidine is a PRMT1-selective, cell-permeable inhibitor (IC50: 9.4μM), also targeting TDP-1, and is an antiparasitic bisbenzamidine derivative.Fórmula:C18H16N4OPureza:98%Cor e Forma:SolidPeso molecular:304.35HDAC ligand-1
CAS:HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].Fórmula:C7H8N2OPureza:98%Cor e Forma:SolidPeso molecular:136.15BET bromodomain inhibitor 2
CAS:BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).Fórmula:C23H30N2O5SCor e Forma:SolidPeso molecular:446.56
