Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2597 produtos de "Cromatina/Epigenética"
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BET bromodomain inhibitor 3
CAS:BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT.Fórmula:C18H17N3O4Pureza:98%Cor e Forma:SolidPeso molecular:339.35Angiogenesis agent 1
CAS:Compound C-31, a salidroside-based glycoside, activates HIF-1α and may aid in diabetic limb ischemia studies.Fórmula:C20H24O7Pureza:98%Cor e Forma:SolidPeso molecular:376.4Eleven-Nineteen-Leukemia Protein IN-1
CAS:ENL-IN-1: Potent ENL YEATS domain inhibitor with 14.5 nM IC50, enhances thermal stability in vitro.Fórmula:C27H33N7O2Pureza:98%Cor e Forma:SolidPeso molecular:487.6JAK-IN-30
CAS:JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50Fórmula:C19H26N8SPureza:98%Cor e Forma:SolidPeso molecular:398.53JAK-IN-28
CAS:JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Fórmula:C20H18ClN7OPureza:98%Cor e Forma:SolidPeso molecular:407.86TM6089
CAS:TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.Fórmula:C13H14N4O3SPureza:99.70%Cor e Forma:SolidPeso molecular:306.34Ref: TM-T17105
1mg52,00€5mg115,00€10mg167,00€25mg301,00€50mg452,00€100mg658,00€200mg884,00€1mL*10mM (DMSO)123,00€EPZ032597
CAS:EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and prevent and treat pancreatic cancerFórmula:C20H23N7OPureza:99.70%Cor e Forma:SolidPeso molecular:377.44(2R/S)-6-PNG
CAS:(2R/S)-6-PNG (6-Prenylnaringenin) from hops is a natural histone deacetylase inhibitor that blocks T-type calcium channels reducing neurogenicity in mice.Fórmula:C20H20O5Pureza:98%Cor e Forma:SolidPeso molecular:340.37DC_C66
CAS:DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.Fórmula:C28H22NO2Pureza:98%Cor e Forma:SolidPeso molecular:404.48AZD-1897
CAS:AZD-1897 is a highly efficient ATP-competitive pan-PIM inhibitor with anti-cancer and anti-leukemia activity, used in multiple myeloma research.Fórmula:C18H23N3O3SPureza:99.49%Cor e Forma:SolidPeso molecular:361.46M-110
CAS:M-110 selectively targets PIM kinases, best at PIM-3 (IC50=47nM), and inhibits prostate cancer cell growth (IC50=0.6-0.9μM).Fórmula:C22H28ClN5O3Pureza:99.55%Cor e Forma:SolidPeso molecular:445.94DDP-38003 dihydrochloride
CAS:DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).Fórmula:C21H28Cl2N4OPureza:99.76%Cor e Forma:SolidPeso molecular:423.38KDM5B-IN-3
CAS:KDM5B-IN-3 inhibits KDM5B/JARID1B with IC50 of 9.32 μM, useful in gastric cancer studies.Fórmula:C19H25ClN4O2Cor e Forma:SolidPeso molecular:376.88Guadecitabine sodium
CAS:Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .Fórmula:C18H24N9NaO10PPureza:98%Cor e Forma:SolidPeso molecular:580.407SC-9
CAS:SC-9 is a protein kinase C activator.Fórmula:C22H24ClNO2SPureza:98%Cor e Forma:SolidPeso molecular:401.95AMPK activator 9
CAS:AMPK activator 9 (ZM-6) is a potent α2β1γ1 agonist with an EC50 of 1.1 µM, potential for type 2 diabetes research.Fórmula:C31H28F4N4O4Cor e Forma:SolidPeso molecular:596.57BRD4-BD1/2-IN-1
CAS:BRD4-BD1/2-IN-1 efficiently blocks BRD4 BD-1/2 under 100 nM IC50 (US20150148375A1, cmpd 5).Fórmula:C21H14F2N4O2Cor e Forma:SolidPeso molecular:392.36PIM1-IN-7
CAS:PIM1-IN-7 inhibits PIM-1 (IC50: 0.67μM), toxic to HCT-116/MCF-7 cells (IC50: 42.9/7.68μM).Fórmula:C23H23N5OCor e Forma:SolidPeso molecular:385.46VE-465
CAS:VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.Fórmula:C22H28N8OSCor e Forma:SolidPeso molecular:452.58PRMT5-IN-17
CAS:PRMT5-IN-17 is a PRMT5-blocking compound with anticancer properties, linked to epigenetic changes.Fórmula:C26H33N7O2Cor e Forma:SolidPeso molecular:475.59
