Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2597 produtos de "Cromatina/Epigenética"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
IACS-9571 hydrochloride
CAS:IACS-9571 hydrochloride: potent TRIM24/BRPF1 inhibitor; IC50 = 8 nM (TRIM24); Kd = 31 nM (TRIM24), 14 nM (BRPF1).Fórmula:C32H43ClN4O8SCor e Forma:SolidPeso molecular:679.22JAK1-IN-4
CAS:JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).Fórmula:C26H32FN9O2Pureza:98%Cor e Forma:SolidPeso molecular:521.59PBRM1-BD2-IN-1
CAS:PBRM1-BD2-IN-1: Selective PBRM1 inhibitor with Kd 0.7μM, IC50 0.2μM, useful in cancer research.Fórmula:C17H19ClN2OCor e Forma:SolidPeso molecular:302.8MC-1353
CAS:MC-1353 is a potent, selective inhibitor of HDAC class I.Fórmula:C16H16N2O3Cor e Forma:SolidPeso molecular:284.31KDM2B-IN-4
CAS:KDM2B-IN-4, from patent WO2016112284A1 as 182b, is a potent KDM2B inhibitor used in cancer research.Fórmula:C24H28N2O2Cor e Forma:SolidPeso molecular:376.49DC-BPi-11
CAS:DC-BPi-11 inhibits BPTF at IC50 698 nM and significantly reduces leukemia cell growth.Fórmula:C20H23N5O2SCor e Forma:SolidPeso molecular:397.49EZH2-IN-11
CAS:EZH2-IN-11, a potent E2HZ inhibitor with potential for cancer treatment, is highlighted in patent WO2019204490A1.Fórmula:C28H36ClN3O5SCor e Forma:SolidPeso molecular:562.12EZH2-IN-9
CAS:EZH2-IN-9 inhibits EZH2, targeting SET mutations linked to cancer by reducing H3K27me3 levels.Fórmula:C28H32ClF2N3O5SCor e Forma:SolidPeso molecular:596.09NN-390
CAS:NN-390: selective HDAC6 inhibitor, IC50 9.8 μM, blood-brain barrier penetrant, potential for metastatic group 3 neural tube cancer research.Fórmula:C17H16F4N2O4SCor e Forma:SolidPeso molecular:420.38AA-CW236
CAS:AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).Fórmula:C17H16ClF3N4O2Cor e Forma:SolidPeso molecular:400.78Antiproliferative agent-17
CAS:Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1].Fórmula:C26H28N2OSCor e Forma:SolidPeso molecular:416.58103D5R
CAS:103D5R selectively inhibits hif-1α, reducing its levels in hypoxia or with cobalt ions, dose- and time-dependently.Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.4Dihydro-5-azacytidine acetate
CAS:Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1Fórmula:C10H18N4O7Pureza:98%Cor e Forma:SolidPeso molecular:306.27TYK2-IN-11
CAS:TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.Fórmula:C18H17N5O3SCor e Forma:SolidPeso molecular:383.42AChE/HDAC-IN-1
CAS:COX-2-IN-23 (A10) inhibits AChE & HDAC (IC50s: 0.12 & 0.23 nM), has antioxidant/metal-binding traits, and is used in Alzheimer's research.Fórmula:C26H27ClN4O3Cor e Forma:SolidPeso molecular:478.97DNMT3A-IN-1
CAS:DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).Fórmula:C30H38N6O4Cor e Forma:SolidPeso molecular:546.66CAY10685
CAS:CAY10685, a CPTH2 analog with an alkyne for click reactions, inhibits NAT10 to study cancer-related chromatin changes.Fórmula:C17H16ClN3SPureza:99.61%Cor e Forma:SolidPeso molecular:329.85BRD4 Inhibitor-25
BRD4 Inhibitor-25 blocks BRD4 (BD1: IC50 0.82 μM, BD2: 1.94 μM), induces cell death in ovarian cancer, used in cancer research.Fórmula:C29H27N5O6SCor e Forma:SolidPeso molecular:573.62BETi-211
CAS:BETi-211 is a selective inhibitor BET bromodomain.Fórmula:C26H29N7O3Cor e Forma:SolidPeso molecular:487.55J1038
CAS:J1038 is a novel Histone Deacetylase 8 (HDAC8) Inhibitor .Fórmula:C10H10N2O3SCor e Forma:SolidPeso molecular:238.26
