Dano de DNA/Reparo de DNA
Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.
Subcategorias de "Dano de DNA/Reparo de DNA"
- ATM/ATR(71 produtos)
- Alquilação de DNA(11 produtos)
- DNA Metiltransferase(422 produtos)
- DNA girase(11 produtos)
- DNA-PK(51 produtos)
- MTH1(1 produtos)
- Nucleosídeo Antimetabólito/Análogo(1.388 produtos)
- Transcriptase reversa(43 produtos)
- Sirtuína(88 produtos)
- Telomerase(33 produtos)
- Topoisomerase(136 produtos)
Exibir 3 mais subcategorias
Foram encontrados 958 produtos de "Dano de DNA/Reparo de DNA"
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Antitumor agent-63
CAS:<p>Compound 40, a non-toxic 20(S)-O-CPT glycoconjugate, is stable, with low Topo I inhibition.</p>Fórmula:C38H46N4O18Cor e Forma:SolidPeso molecular:846.79Prednimustine
CAS:<p>Prednimustine (Leo 1031; NSC 134087), an ester of Prednisolone and Chlorambucil, is used in leukemia and lymphoma studies.</p>Fórmula:C35H45Cl2NO6Cor e Forma:SolidPeso molecular:646.64TAK1 inhibitor
CAS:<p>TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively.</p>Fórmula:C22H19ClN6O2SPureza:98%Cor e Forma:SoildPeso molecular:466.94Wistin
CAS:<p>Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .</p>Fórmula:C23H24O10Cor e Forma:SolidPeso molecular:460.43PR-104 sodium
CAS:<p>PR-104 sodium: hypoxia-activated, tumor-targeting pre-prodrug; turns into PR-104A for research.</p>Fórmula:C14H19BrN4NaO12PSCor e Forma:SolidPeso molecular:601.25AZD-5099
CAS:<p>AZD-5099 is a DNA gyrase modulator potentially for the treatment of bacterial infection.</p>Fórmula:C21H27Cl2N5O6SCor e Forma:SolidPeso molecular:548.44Topo I/II-IN-1
<p>Topo I/II-IN-1 (compound 7t) is an effective dual inhibitor of Topo I and Topo II. It exhibits significant cytotoxicity against the MCF-7 breast cancer cell line, with an IC50 value of 7.45 μM.</p>Fórmula:C15H13N3S2Cor e Forma:SolidPeso molecular:299.414PPARγ/GR modulator 1
<p>PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibits</p>Fórmula:C14H10FNO4Cor e Forma:SolidPeso molecular:275.23Elinafide
CAS:<p>Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays.</p>Fórmula:C31H28N4O4Pureza:97.29%Cor e Forma:SolidPeso molecular:520.58AuM1Phe
<p>AuM1Phe, an N-heterocyclic carbene (NHC) metal complex, inhibits both human topoisomerase I activity and actin polymerization.</p>Pureza:98%Cor e Forma:Odour SolidARN24139
<p>ARN24139: a topoisomerase II poison; IC50=7.3μM. Inhibits DU145, HeLa, A549 cell growth; IC50s=4.7, 3.8, 3.1μM.</p>Cor e Forma:SolidWAY-323061
CAS:<p>WAY-323061 is a SIRT2 inhibitor.</p>Fórmula:C25H21N5O2SPureza:99.33%Cor e Forma:SolidPeso molecular:455.53Elomotecan hydrochloride
CAS:<p>Elomotecan hydrochloride (BN 80927), a potent hCPT analog, inhibits topoisomerases I/II, outperforming other anticancer drugs.</p>Fórmula:C29H33Cl2N3O4Cor e Forma:SolidPeso molecular:558.5PARP1-IN-33
CAS:<p>PARP1-IN-33 (Example 6) is a PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates protective effects on retinal cells, exhibiting an EC50 of 0.02 nM in inhibiting hydrogen peroxide-induced MTS activity in human retinal pigment epithelial cells.</p>Fórmula:C23H24ClFN4OCor e Forma:SolidPeso molecular:426.91AuL1
<p>AuL1 is a topoisomerase IIα (Top II) inhibitor with DNA intercalating properties. It exhibits cytotoxic effects on tumor cells, making it a potential subject for anticancer agent research.</p>Fórmula:C29H50AuCl2N5Cor e Forma:SolidPeso molecular:736.61Sulotroban
CAS:<p>sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.</p>Fórmula:C16H17NO5SPureza:98.86% - 99.88%Cor e Forma:SolidPeso molecular:335.37PNU-142586
CAS:<p>PNU-142586 is a bio-active chemical.</p>Fórmula:C16H20FN3O6Cor e Forma:SolidPeso molecular:369.34Banoxantrone (D12)
CAS:<p>Banoxantrone D12, deuterium-labeled version, reduces to AQ4 - a stable DNA-targeting topoisomerase II inhibitor.</p>Fórmula:C22H28N4O6Pureza:98%Cor e Forma:SolidPeso molecular:456.55Amrubicin
CAS:<p>The compound is a synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II.</p>Fórmula:C25H25NO9Pureza:98%Cor e Forma:SolidPeso molecular:483.47Gimatecan HCl
<p>Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.</p>Fórmula:C25H26ClN3O5Pureza:97.04%Cor e Forma:SoildPeso molecular:483.94DNA Damage & Repair Compound Library
<p>A unique collection of xnum DNA Damage &amp; Repair related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidATM Inhibitor-9
<p>ATM Inhibitor-9 (Compd 7a) is a potent inhibitor of ATM kinase, exhibiting an IC50 value of 5 nM, and is utilized in cancer research [1].</p>Fórmula:C25H32N6O2Pureza:98%Cor e Forma:SolidPeso molecular:448.56VH 032 amide-PEG1-acid
CAS:<p>VHL ligand for PROTAC R&D; E3 ligase with PEG1 linker and carboxylic acid for target conjugation.</p>Fórmula:C28H38N4O7SCor e Forma:SolidPeso molecular:574.69Ketopioglitazone
CAS:<p>Ketopioglitazone is an active metabolite of pioglitazone.</p>Fórmula:C19H18N2O4SCor e Forma:SolidPeso molecular:370.42CUDA disodium
<p>CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.</p>Cor e Forma:Odour SolidPericosine A
CAS:<p>Pericosine A, a fungal metabolite from P. byssoides, shows anticancer effects (GI50s = 0.05-24.55 μM) and EGFR inhibition (40-70% at 100 μg/ml).</p>Fórmula:C8H11ClO5Cor e Forma:SolidPeso molecular:222.62Silatecan
CAS:<p>Silatecan is a useful organic compound for research related to life sciences. The catalog number is T67968 and the CAS number is 220913-32-6.</p>Fórmula:C26H30N2O5SiCor e Forma:SoildPeso molecular:478.61HDAC-IN-64
<p>HDAC-IN-64 (Compound 13), an HDAC inhibitor, demonstrates potent inhibition of HDAC4/5/6/7/9 with IC50 values of 24, 45, 85, 31, and 37 nM, respectively.</p>Fórmula:C15H8ClF4N7OPureza:98%Cor e Forma:SolidPeso molecular:413.72GK718
<p>GK718, a selective HDAC1/3 inhibitor with IC50 values of 259 nM and 139 nM, respectively, elevates acetylated histone H3 levels in cells and mitigates Bleomycin</p>Pureza:98%Cor e Forma:Odour SolidNH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride
<p>Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride, is a topoisomerase I inhibitor that demonstrates effective antibody-drug conjugate (ADC)</p>Fórmula:C26H24ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:509.94FKB04
<p>FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanisms in hepatocellular carcinoma cells. This leads to T-loop defects, inducing telomere shortening and cellular senescence. Additionally, FKB04 inhibits tumor growth in a human liver cancer xenograft mouse model (by implanting Huh-7 cells in BALB/c mice). This compound is utilized in research focused on liver cancer.</p>Cor e Forma:Odour SolidYCH1899
<p>YCH1899, an orally active PARP inhibitor, demonstrates potent inhibition of PARP1/2 with an IC50 of less than 0.001 nM.</p>Fórmula:C25H18BrFN6O3Pureza:98%Cor e Forma:SolidPeso molecular:549.35CL2-MMT-SN38
CAS:<p>CL2-MMT-SN38 is a derivative of SN-38, which is a potent anticancer agent and the active metabolite of Irinotecan (CPT-11), a Topoisomerase I inhibitor.</p>Fórmula:C102H122N12O24Cor e Forma:SolidPeso molecular:1900.158GW 1929 hydrochloride
CAS:<p>Oral PPARγ agonist with pEC50 of 8.05; low affinity for PPARα, PPARδ. Reduces blood glucose, fatty acids, triglycerides in vivo.</p>Fórmula:C30H30ClN3O4Cor e Forma:SolidPeso molecular:532.0415-LOX-IN-2
<p>15-LOX-IN-2 (Compound 2a) is an orally active inhibitor of COX-2/15-LOX and a partial agonist of PPARγ. It exhibits anti-inflammatory activity by inhibiting levels of 20-HETE, IL-1β, and TNF-α in LPS-treated RAW 264.7 cells. Additionally, it significantly enhances glucose uptake without the presence of insulin and is applicable in metabolic disease research.</p>Cor e Forma:Odour Solid20-carboxy Arachidonic Acid
CAS:<p>20-COOH-AA, 20-HETE metabolite, inhibits kidney ion transport, relaxes constricted vessels, and activates PPARα/γ.</p>Fórmula:C20H30O4Cor e Forma:SolidPeso molecular:334.456HDAC6-IN-23
<p>HDAC6-IN-23 (compound 9), an orally active inhibitor of HDAC6 [1], displays selective enzymatic inhibition.</p>Fórmula:C15H10F2N8OPureza:98%Cor e Forma:SolidPeso molecular:356.29HDAC-IN-61
<p>HDAC-IN-61 (compound 12k) is a potent, orally active inhibitor of histone deacetylase (HDAC) with anticancer activity, exhibiting an IC50 of 30 nM against Bel-</p>Fórmula:C28H27N3O5Pureza:98%Cor e Forma:SolidPeso molecular:485.53DNMT1/HDAC-IN-1
<p>DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory effects specifically on HDAC1 (HDAC1:IC50=0.05 μM), a major HDAC isoform that interacts with DNMT1 across multiple protein complexes involved in the transcriptional silencing of TSGs. This compound has been shown to remodel the tumor immune microenvironment and induce tumor regression, effectively reversing cancer-specific epigenetic abnormalities.</p>Cor e Forma:Odour SolidHeliotrine N-oxide
CAS:<p>Heliotrine N-oxide, a PA N-oxide, triggers pyrrolic DNA adducts and may cause liver tumors.</p>Fórmula:C16H27NO6Cor e Forma:SolidPeso molecular:329.393Topoisomerase I/II inhibitor 5
<p>TopoisomeraseI/II inhibitor 5 (compound 1) stabilizes G4 structures through binding and concurrently inhibits the relaxation activities of TopoI and II.</p>Cor e Forma:Odour SolidSIRT-IN-5
<p>SIRT-IN-5, a selective inhibitor of SIRT3 with an IC50 of 2.88 μM, facilitates the differentiation of multiple myeloma cells. This differentiation is associated with increased expression of the differentiation antigens CD49e and human immunoglobulin light chains λ and κ.</p>Cor e Forma:Odour Solid1-Methyladenosine-d3
<p>1-Methyladenosine-d3 hydrochloride is the hydrochloride salt form of deuterium-labeled 1-Methyladenosine. This compound is a modification of RNA that serves as a biomarker for tumors, with elevated levels in the body linked to cancer development. Upon methylation, 1-Methyladenosine upregulates the expression of PPARδ, regulates cholesterol metabolism, and activates the Hedgehog signaling pathway, thereby driving the onset of liver tumors.</p>Cor e Forma:Odour SolidIC 86621
CAS:<p>IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM for repair.</p>Fórmula:C12H15NO3Pureza:99.68%Cor e Forma:SolidPeso molecular:221.25PARP/HDAC-IN-1
<p>PARP/HDAC-IN-1 is a PARP and HDAC inhibitor that inhibits PARP1, PARP2, and HDAC1, and may be used to study pancreatic cancer.</p>Fórmula:C36H32F2N6O3Pureza:95.00%Cor e Forma:SolidPeso molecular:634.67Gemfibrozil 1-O-β-glucuronide
CAS:<p>Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil , is a potent and competitive P450 (CYP) isoform CYP2C8 inhibitor with an IC50 of 4.07 μM.</p>Fórmula:C21H30O9Pureza:98%Cor e Forma:SolidPeso molecular:426.46Anticancer agent 177
<p>Anticanceragent 177 (Compound 11b) is an NAMPT inhibitor and DNA alkylating agent with antitumor activity both in vitro and in vivo.</p>Fórmula:C28H36Cl2N4O2Peso molecular:530.22153Stearolic acid
CAS:<p>Stearolic acid is a useful organic compound for research related to life sciences. The catalog number is T124753 and the CAS number is 506-24-1.</p>Fórmula:C18H32O2Cor e Forma:SolidPeso molecular:280.45223-epi-26-Deoxyactein
CAS:<p>23-epi-26-Deoxyactein is a naturally occurring compound exhibiting anti-obesity and anti-cancer properties when administered orally [1] [2] [3].</p>Fórmula:C37H56O10Cor e Forma:SolidPeso molecular:660.83Murrayanol
<p>Murrayanol is a useful organic compound for research related to life sciences and the catalog number is T125851.</p>Fórmula:C24H29NO2Cor e Forma:SolidPeso molecular:363.501Colibactin 742
CAS:<p>Colibactin 742, a stable derivative of colibactin, efficiently induces DNA interstrand cross-links, activates the Fanconi Anemia DNA repair pathway, and leads</p>Fórmula:C37H42N8O5S2Cor e Forma:SolidPeso molecular:742.91BML-278
CAS:<p>BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and</p>Fórmula:C24H25NO4Pureza:99.53%Cor e Forma:SolidPeso molecular:391.46SCR7
CAS:<p>SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).</p>Fórmula:C18H14N4OSPureza:98%Cor e Forma:SolidPeso molecular:334.4(±)9-HEPE
CAS:<p>(±)9-HEPE is produced by non-enzymatic oxidation of EPA.</p>Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.457Tibesaikosaponin V
CAS:<p>TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.</p>Fórmula:C42H68O15Cor e Forma:SolidPeso molecular:812.98Melphalan
CAS:<p>Melphalan is an alkylating agent. It has been used in combination with the HDAC inhibitor as a drug for the treatment of multiple myeloma (MM) cell lines and as a chemotherapy agent for breast cancer cell lines.</p>Fórmula:C13H18Cl2N2O2Peso molecular:305.21Leriglitazone hydrochloride
CAS:<p>Leriglitazone hydrochloride, a pioglitazone metabolite, is a PPARγ agonist with Ki of 1.2 μM and EC50 of 680 nM.</p>Fórmula:C19H21ClN2O4SCor e Forma:SolidPeso molecular:408.90MS9024
<p>MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299). Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 μM.</p>Cor e Forma:Odour SolidPhosphoramide mustard
CAS:<p>Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage.</p>Fórmula:C4H11Cl2N2O2PPureza:93.00%Cor e Forma:SolidPeso molecular:221.02GSK3735967
CAS:<p>GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.</p>Fórmula:C25H31N7OSCor e Forma:SolidPeso molecular:477.62BRD7586
CAS:<p>BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.</p>Fórmula:C17H14ClN3O3S2Pureza:97.70% - 99.03%Cor e Forma:SolidPeso molecular:407.89VK-1727
<p>VK-1727 inhibits EBNA1 DNA binding, reducing proliferation of EBV-positive cells while sparing EBV-negative cells, useful for multiple sclerosis research.</p>Fórmula:C29H25NO4Pureza:98.074%Cor e Forma:SolidPeso molecular:451.512'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS:<p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>Fórmula:C9H13ClFN3O4Pureza:99.69%Cor e Forma:SolidPeso molecular:281.67(4-NH2)-Exatecan
CAS:<p>(4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).</p>Fórmula:C23H21N3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:403.43O6BTG-octylglucoside
CAS:O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).Fórmula:C24H34BrN5O7SPureza:98%Cor e Forma:SolidPeso molecular:616.53Banoxantrone dihydrochloride
CAS:<p>Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.</p>Fórmula:C22H30Cl2N4O6Pureza:99.88%Cor e Forma:SolidPeso molecular:517.45'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
CAS:<p>5'-O-DMT-dU, a dUTPase inhibitor (Ki > 1 mM) for E. coli, is used in DNA synthesis.</p>Fórmula:C30H30N2O7Cor e Forma:SolidPeso molecular:530.57Heptaplatin
CAS:<p>Heptaplatin, an anticancer platinum compound, counters many cancers, including cisplatin-resistant types, with a 17% response rate and tolerable toxicity.</p>Fórmula:C11H20N2O6PtCor e Forma:White Crystalline PowderPeso molecular:471.36HDAC-IN-4
CAS:<p>HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.</p>Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.4SIRT5 inhibitor 3
CAS:<p>SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .</p>Fórmula:C22H12FN3O4Pureza:98%Cor e Forma:SolidPeso molecular:401.35Methyl methanesulfonate (Standard)
CAS:<p>Methyl methanesulfonate (Standard) is a standard material used in the analysis of methyl methanesulfonate, typically referenced in its research and analysis.</p>Fórmula:C2H6O3SCor e Forma:SolidPeso molecular:110.13Balaglitazone
CAS:<p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>Fórmula:C20H17N3O4SPureza:99.74%Cor e Forma:SolidPeso molecular:395.43CP-868388 free base
CAS:<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Fórmula:C26H33NO5Pureza:99.84%Cor e Forma:SolidPeso molecular:439.54(R)-(+)-Bay-K-8644
CAS:<p>(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.</p>Fórmula:C16H15F3N2O4Pureza:96.51% - 96.51%Cor e Forma:SolidPeso molecular:356.3Gepotidacin
CAS:<p>Gepotidacin is a triazaacenaphthylene antibacterial inhibiting bacterial type II topoisomerase with lower resistance potential than fluoroquinolones.</p>Fórmula:C24H28N6O3Pureza:99.88%Cor e Forma:SolidPeso molecular:448.52AMA-37
CAS:<p>AMA-37 is a selective, reversible, and ATP-competitive DNA-PK inhibitor.</p>Fórmula:C17H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:283.32Daun02
CAS:<p>Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.</p>Fórmula:C41H44N2O20Pureza:98%Cor e Forma:SolidPeso molecular:884.79Gancaonin L
CAS:<p>Gancaonin L is a natural product that can be used as a reference standard. The CAS number of Gancaonin L is 129145-50-2.</p>Fórmula:C20H18O6Cor e Forma:SolidPeso molecular:354.3589-Hydroxyellipticin free base
CAS:<p>9-hydroxyellipticine is a potent cytotoxic and antitumor agent. 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine.</p>Fórmula:C17H14N2OCor e Forma:SolidPeso molecular:262.31Phosphoramide mustard cyclohexanamine
CAS:<p>Phosphoramide mustard cyclohexanamine is active metabolite of cyclophosphamide, an alkylating agent that cross-links DNA strands,causes cell death, antitumor.</p>Fórmula:C10H24Cl2N3O2PPureza:95%Cor e Forma:SolidPeso molecular:320.2RPR121056
CAS:<p>RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.</p>Fórmula:C33H38N4O8Pureza:98%Cor e Forma:SolidPeso molecular:618.68Gatifloxacin mesylate
CAS:<p>Gatifloxacin mesylate, a 4th-gen fluoroquinolone antibiotic, inhibits DNA gyrase and topoisomerase IV.</p>Fórmula:C20H26FN3O7SPureza:98%Cor e Forma:SolidPeso molecular:471.5Gatifloxacin sesquihydrate
CAS:<p>Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia.</p>Fórmula:C19H24FN3O5Cor e Forma:SolidPeso molecular:393.41Telomerase-IN-3
CAS:<p>Telomerase-IN-3 is an inhibitor of telomerase.</p>Fórmula:C19H16ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:397.82Epitalon
CAS:<p>Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.</p>Fórmula:C14H22N4O9Pureza:98%Cor e Forma:SolidPeso molecular:390.35(R)-GSK-3685032
CAS:<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Fórmula:C22H24N6OSCor e Forma:SolidPeso molecular:420.54Ciprofloxacin hydrochloride monohydrate
CAS:<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Fórmula:C17H21ClFN3O4Pureza:99.23% - 99.85%Cor e Forma:White Or Yellowish Crystalline PowderPeso molecular:385.82PTGR2-IN-1
CAS:<p>PTGR2-IN-1 is a potent inhibito of PTGR2r. PTGR2-IN-1 increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.</p>Fórmula:C19H22N2O2Pureza:99.13%Cor e Forma:SolidPeso molecular:310.39YK-3-237
CAS:<p>YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative</p>Fórmula:C19H21BO7Pureza:99.47%Cor e Forma:SolidPeso molecular:372.18Pentamidine dihydrochloride
CAS:<p>Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (</p>Fórmula:C19H26Cl2N4O2Pureza:99.80%Cor e Forma:SolidPeso molecular:413.34Pixantrone dimaleate
CAS:<p>Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.</p>Fórmula:C25H27N5O10Pureza:98.70% - 99.11%Cor e Forma:SolidPeso molecular:557.21Silver sulfadiazine
CAS:<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Fórmula:C10H9AgN4O2SPureza:99.04% - 99.58%Cor e Forma:SolidPeso molecular:357.14BYK204165
CAS:<p>BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)</p>Fórmula:C15H12N2O2Pureza:99.61%Cor e Forma:SolidPeso molecular:252.27AK-7
CAS:<p>AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.</p>Fórmula:C19H21BrN2O3SPureza:98.43% - 99.34%Cor e Forma:SolidPeso molecular:437.35Voxtalisib
CAS:<p>Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.</p>Fórmula:C13H14N6OPureza:98.21% - 99.69%Cor e Forma:SolidPeso molecular:270.29Remetinostat
CAS:<p>Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell</p>Fórmula:C16H21NO6Pureza:98.67%Cor e Forma:SolidPeso molecular:323.34Pixantrone hydrochloride
CAS:<p>Pixantrone hydrochloride is a topoisomerase II inhibitor and DNA intercalator with anti-tumor properties.</p>Fórmula:C17H20ClN5O2Cor e Forma:SolidPeso molecular:361.83PJ34
CAS:<p>PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.</p>Fórmula:C17H17N3O2Pureza:95.05% - 99.85%Cor e Forma:SolidPeso molecular:295.34Resminostat hydrochloride
CAS:<p>Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent</p>Fórmula:C16H20ClN3O4SPureza:97.63% - 99.68%Cor e Forma:SolidPeso molecular:385.86L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Cor e Forma:SolidPeso molecular:486.11
