Dano de DNA/Reparo de DNA

Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.

Subcategorias de "Dano de DNA/Reparo de DNA"

Exibir 3 mais subcategorias

Foram encontrados 958 produtos de "Dano de DNA/Reparo de DNA"

Pureza (%)

100

produtos por página.

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Elomotecan
CAS:
- 220998-10-7
Elomotecan (BN 80927 free base) is a potent inhibitor of topoisomerases I and II.Cost-effective and quality-assured.
Fórmula:C₂₉H₃₂ClN₃O₄
Cor e Forma:Solid
Peso molecular:522.04
Ref: TM-T68062
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(R)-VX-984
CAS:
- 2448475-19-0
(R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent inhibitor of DNA-PK.
Fórmula:C₂₃H₂₁D₂N₇O
Pureza:98%
Cor e Forma:Solid
Peso molecular:415.49
Ref: TM-T12648
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Prednimustine
CAS:
- 29069-24-7
Prednimustine (Leo 1031; NSC 134087), an ester of Prednisolone and Chlorambucil, is used in leukemia and lymphoma studies.
Fórmula:C₃₅H₄₅Cl₂NO₆
Cor e Forma:Solid
Peso molecular:646.64
Ref: TM-T74096
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GJ071 oxalate
CAS:
- 1216676-34-4
GJ071 oxalate is a Nonsense suppressor that induces readthrough by inserting amino acids at premature termination codons.
Fórmula:C₂₀H₂₉N₃O₇S
Pureza:99.97%
Cor e Forma:Solid
Peso molecular:455.53
Ref: TM-T31932
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Et-29
CAS:
- 2166487-23-4
Et-29 is a selective inhibitor of SIRT5 inhibitor with a Ki of 40 nM.
Fórmula:C₃₄H₄₆N₆O₆S
Pureza:99.52%
Cor e Forma:Solid
Peso molecular:666.83
Ref: TM-T35347
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PPAR agonist 6
PPAR agonist6 (compound 5a) acts as an agonist for PPAR, exhibiting EC50 values of 3.6 μM and 2.6 μM for PPARα and PPARβ/δ respectively. Additionally, PPAR agonist6 inhibits the transactivation of a TNFα-dependent NF-κB-driven reporter gene in L929 cells [1].
Cor e Forma:Odour Solid
Ref: TM-T206860
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Tibesaikosaponin V
CAS:
- 2319668-87-4
TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.
Fórmula:C₄₂H₆₈O₁₅
Cor e Forma:Solid
Peso molecular:812.98
Ref: TM-T75611
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PPARγ/GR modulator 1
PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibits
Fórmula:C₁₄H₁₀FNO₄
Cor e Forma:Solid
Peso molecular:275.23
Ref: TM-T75009
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TUG-499
CAS:
- 1206629-08-4
TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptors
Fórmula:C₁₆H₁₁Cl₂NO₂
Pureza:99.93%
Cor e Forma:Soild
Peso molecular:320.17
Ref: TM-T60184
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PARP/HDAC-IN-1
PARP/HDAC-IN-1 is a PARP and HDAC inhibitor that inhibits PARP1, PARP2, and HDAC1, and may be used to study pancreatic cancer.
Fórmula:C₃₆H₃₂F₂N₆O₃
Pureza:95.00%
Cor e Forma:Solid
Peso molecular:634.67
Ref: TM-T85321
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Sibiromycin
CAS:
- 12684-33-2
Sibiromycin: natural, potent antitumor PBD that binds DNA's minor groove at guanine NH2.
Fórmula:C₂₄H₃₃N₃O₇
Cor e Forma:Solid
Peso molecular:475.542
Ref: TM-T38673
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Hippeastrine Hydrobromide
CAS:
- 22352-41-6
Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.
Fórmula:C₁₇H₁₈BrNO₅
Cor e Forma:Solid
Peso molecular:396.237
Ref: TM-T32077
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AZD-5099
CAS:
- 907543-25-3
AZD-5099 is a DNA gyrase modulator potentially for the treatment of bacterial infection.
Fórmula:C₂₁H₂₇Cl₂N₅O₆S
Cor e Forma:Solid
Peso molecular:548.44
Ref: TM-T26717
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GSK3735967
CAS:
- 2170136-86-2
GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.
Fórmula:C₂₅H₃₁N₇OS
Cor e Forma:Solid
Peso molecular:477.62
Ref: TM-T74887
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Sulotroban
CAS:
- 72131-33-0
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
Fórmula:C₁₆H₁₇NO₅S
Pureza:98.86% - 99.88%
Cor e Forma:Solid
Peso molecular:335.37
Ref: TM-T68022
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Ciprofibrate impurity A
CAS:
- 1474058-89-3
Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate is a PPARα agonist[1].
Fórmula:C₁₂H₁₄O₃
Cor e Forma:Solid
Peso molecular:206.241
Ref: TM-T36076
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Antitumor agent-28
CAS:
- 2097499-67-5
Antitumor agent-28 inhibits ATM kinase, blocking ATM disease progression and showing anti-cancer effects.
Fórmula:C₂₅H₃₂N₆O₄S
Cor e Forma:Solid
Peso molecular:512.63
Ref: TM-T39523
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1-O-Hexadecyl-Rac-Glycerol
CAS:
- 6145-69-3
1-O-Hexadecyl-Rac-Glycerol (1-O-Hexadecylglycerol) is a marine derived natural products found in Tritoniella belli.
Fórmula:C₁₉H₄₀O₃
Pureza:99.94%
Cor e Forma:Solid
Peso molecular:316.52
Ref: TM-TN7182
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Z26395438
CAS:
- 2803-63-6
Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.
Fórmula:C₁₇H₁₅FN₂O
Pureza:99.63%
Cor e Forma:Solid
Peso molecular:282.31
Ref: TM-T77653
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Becatecarin
CAS:
- 119673-08-4
Becatecarin, water-soluble and anti-cancer, inhibits topoisomerases I/II and induces DNA cleavage and apoptosis; has myelosuppressive effects; ABCG2 substrate.
Fórmula:C₃₃H₃₄Cl₂N₄O₇
Cor e Forma:Solid
Peso molecular:669.56
Ref: TM-T36485