Dano de DNA/Reparo de DNA
Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.
Subcategorias de "Dano de DNA/Reparo de DNA"
- ATM/ATR(71 produtos)
- Alquilação de DNA(11 produtos)
- DNA Metiltransferase(422 produtos)
- DNA girase(11 produtos)
- DNA-PK(50 produtos)
- MTH1(1 produtos)
- Nucleosídeo Antimetabólito/Análogo(1.388 produtos)
- Transcriptase reversa(43 produtos)
- Sirtuína(88 produtos)
- Telomerase(33 produtos)
- Topoisomerase(136 produtos)
Exibir 3 mais subcategorias
Foram encontrados 963 produtos de "Dano de DNA/Reparo de DNA"
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PARP/HDAC-IN-1
<p>PARP/HDAC-IN-1 is a PARP and HDAC inhibitor that inhibits PARP1, PARP2, and HDAC1, and may be used to study pancreatic cancer.</p>Fórmula:C36H32F2N6O3Pureza:95.00%Cor e Forma:SolidPeso molecular:634.671-Methyladenosine-d3
<p>1-Methyladenosine-d3 hydrochloride is the hydrochloride salt form of deuterium-labeled 1-Methyladenosine. This compound is a modification of RNA that serves as a biomarker for tumors, with elevated levels in the body linked to cancer development. Upon methylation, 1-Methyladenosine upregulates the expression of PPARδ, regulates cholesterol metabolism, and activates the Hedgehog signaling pathway, thereby driving the onset of liver tumors.</p>Cor e Forma:Odour SolidPARP-1-IN-13
<p>PARP-1-IN-13 (Compound 19c) is a potent PARP-1 inhibitor with an IC50 of 26 nM, hindering DNA single-strand break repair and exacerbating DNA double-strand</p>Fórmula:C20H17N5O2SPureza:98%Cor e Forma:SolidPeso molecular:391.45Epitalon
CAS:<p>Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.</p>Fórmula:C14H22N4O9Pureza:98%Cor e Forma:SolidPeso molecular:390.35Banoxantrone dihydrochloride
CAS:<p>Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.</p>Fórmula:C22H30Cl2N4O6Pureza:99.88%Cor e Forma:SolidPeso molecular:517.4HDAC-IN-4
CAS:HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.42'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS:<p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>Fórmula:C9H13ClFN3O4Pureza:99.69%Cor e Forma:SolidPeso molecular:281.67O6BTG-octylglucoside
CAS:O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).Fórmula:C24H34BrN5O7SPureza:98%Cor e Forma:SolidPeso molecular:616.53(R)-(+)-Bay-K-8644
CAS:<p>(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.</p>Fórmula:C16H15F3N2O4Pureza:96.51% - 96.51%Cor e Forma:SolidPeso molecular:356.3Gatifloxacin mesylate
CAS:<p>Gatifloxacin mesylate, a 4th-gen fluoroquinolone antibiotic, inhibits DNA gyrase and topoisomerase IV.</p>Fórmula:C20H26FN3O7SPureza:98%Cor e Forma:SolidPeso molecular:471.5Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Fórmula:C20H17N3O4SPureza:99.74%Cor e Forma:SolidPeso molecular:395.43Methyl methanesulfonate (Standard)
CAS:<p>Methyl methanesulfonate (Standard) is a standard material used in the analysis of methyl methanesulfonate, typically referenced in its research and analysis.</p>Fórmula:C2H6O3SCor e Forma:SolidPeso molecular:110.13Heptaplatin
CAS:<p>Heptaplatin, an anticancer platinum compound, counters many cancers, including cisplatin-resistant types, with a 17% response rate and tolerable toxicity.</p>Fórmula:C11H20N2O6PtCor e Forma:White Crystalline PowderPeso molecular:471.36CP-868388 free base
CAS:<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Fórmula:C26H33NO5Pureza:99.84%Cor e Forma:SolidPeso molecular:439.545'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
CAS:5'-O-DMT-dU, a dUTPase inhibitor (Ki > 1 mM) for E. coli, is used in DNA synthesis.Fórmula:C30H30N2O7Cor e Forma:SolidPeso molecular:530.57SIRT5 inhibitor 3
CAS:<p>SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .</p>Fórmula:C22H12FN3O4Pureza:98%Cor e Forma:SolidPeso molecular:401.35(R)-GSK-3685032
CAS:<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Fórmula:C22H24N6OSCor e Forma:SolidPeso molecular:420.54Gancaonin L
CAS:<p>Gancaonin L is a natural product that can be used as a reference standard. The CAS number of Gancaonin L is 129145-50-2.</p>Fórmula:C20H18O6Cor e Forma:SolidPeso molecular:354.3589-Hydroxyellipticin free base
CAS:<p>9-hydroxyellipticine is a potent cytotoxic and antitumor agent. 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine.</p>Fórmula:C17H14N2OCor e Forma:SolidPeso molecular:262.31Gepotidacin
CAS:Gepotidacin is a triazaacenaphthylene antibacterial inhibiting bacterial type II topoisomerase with lower resistance potential than fluoroquinolones.Fórmula:C24H28N6O3Pureza:99.88%Cor e Forma:SolidPeso molecular:448.52
