Dano de DNA/Reparo de DNA

Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.

Subcategorias de "Dano de DNA/Reparo de DNA"

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Foram encontrados 958 produtos de "Dano de DNA/Reparo de DNA"

Pureza (%)

100

produtos por página.

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Ganciclovir sodium
CAS:
- 107910-75-8
Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.
Fórmula:C₉H₁₃N₅NaO₄
Pureza:99.93%
Cor e Forma:Solid
Peso molecular:278.22
Ref: TM-T22337
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Clofibrate
CAS:
- 637-07-0
Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.
Fórmula:C₁₂H₁₅ClO₃
Pureza:98.77%
Cor e Forma:Oil Liquid
Peso molecular:242.70
Ref: TM-T1298
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Azemiglitazone
CAS:
- 1133819-87-0
Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.
Fórmula:C₁₉H₁₇NO₅S
Pureza:98.29% - 99.6%
Cor e Forma:Solid
Peso molecular:371.41
Ref: TM-T4639
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LMK-235
CAS:
- 1418033-25-6
LMK-235 is a potent HDAC inhibitor, and is used in cancer research.
Fórmula:C₁₅H₂₂N₂O₄
Pureza:98.18% - 99.68%
Cor e Forma:Solid
Peso molecular:294.35
Ref: TM-T6061
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Altretamine hydrochloride
CAS:
- 2975-00-0
Altretamine hydrochloride is an alkylating antineoplastic agent.
Fórmula:C₉H₁₉ClN₆
Cor e Forma:Solid
Peso molecular:246.74
Ref: TM-T72217
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Ensulizole
CAS:
- 27503-81-7
Ensulizole, a water-soluble UV absorber, damages DNA by generating ROS under UV light, and absorbs UVB and some UVA.
Fórmula:C₁₃H₁₀N₂O₃S
Pureza:99.79%
Cor e Forma:White To Pale Beige Solid Powder
Peso molecular:274.30
Ref: TM-T19310
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NU1025
CAS:
- 90417-38-2
NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.
Fórmula:C₉H₈N₂O₂
Pureza:99.86%
Cor e Forma:Solid
Peso molecular:176.17
Ref: TM-T6912
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T0070907
CAS:
- 313516-66-4
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
Fórmula:C₁₂H₈ClN₃O₃
Pureza:98.25% - 99.98%
Cor e Forma:Solid
Peso molecular:277.66
Ref: TM-T6689
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UBCS039
CAS:
- 358721-70-7
UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)
Fórmula:C₁₆H₁₃N₃
Pureza:98.31%
Cor e Forma:Solid
Peso molecular:247.29
Ref: TM-T7679
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Belotecan hydrochloride
CAS:
- 213819-48-8
Belotecan hydrochloride (CKD-602) is a synthetic water-soluble camptothecin derivative and topoisomerase I inhibitor with potential antitumor activity
Fórmula:C₂₅H₂₈ClN₃O₄
Pureza:99.63% - ≥95%
Cor e Forma:Solid
Peso molecular:469.96
Ref: TM-T7551
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2',3',5'-triacetyl-5-Azacytidine
CAS:
- 10302-78-0
2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.
Fórmula:C₁₄H₁₈N₄O₈
Pureza:98.34%
Cor e Forma:Solid
Peso molecular:370.31
Ref: TM-T7840
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PI-3065
CAS:
- 955977-50-1
PI-3065 is a novel potent and selective PI3K p110δ inhibitor.
Fórmula:C₂₇H₃₁FN₆OS
Pureza:99.84% - ≥95%
Cor e Forma:Solid
Peso molecular:506.64
Ref: TM-T2083
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SRT 1720
CAS:
- 925434-55-5
SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.
Fórmula:C₂₅H₂₃N₇OS
Pureza:98.84%
Cor e Forma:Solid
Peso molecular:469.56
Ref: TM-T5096
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Tasquinimod
CAS:
- 254964-60-8
Tasquinimod (ABR-215050) is an oral antiangiogenic agent and S100A9 inhibitor that binds to the HDAC4Zn2+ binding structural domain with Kd values ranging from 10 to 30 nM.Cost-effective and quality-assured.
Fórmula:C₂₀H₁₇F₃N₂O₄
Pureza:99.22% - >99.99%
Cor e Forma:Solid
Peso molecular:406.36
Ref: TM-T6695
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TH34
CAS:
- 2196203-96-8
TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.
Fórmula:C₁₅H₁₆N₂O₂
Pureza:98.32%
Cor e Forma:Solid
Peso molecular:256.3
Ref: TM-T5332
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M344
CAS:
- 251456-60-7
M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.
Fórmula:C₁₆H₂₅N₃O₃
Pureza:98.18%
Cor e Forma:Solid
Peso molecular:307.39
Ref: TM-T2157
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KU60019
CAS:
- 925701-49-1
Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.
Fórmula:C₃₀H₃₃N₃O₅S
Pureza:95.9% - 99.36%
Cor e Forma:Solid
Peso molecular:547.67
Ref: TM-T2474
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KCC-07
CAS:
- 315702-75-1
KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.
Fórmula:C₁₄H₁₁N₃OS
Pureza:98.86% - 99.01%
Cor e Forma:Solid
Peso molecular:269.32
Ref: TM-T8554
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CM-579 trihydrochloride
CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.
Fórmula:C₂₉H₄₃Cl₃N₄O₃
Cor e Forma:Solid
Peso molecular:602.04
Ref: TM-T72277
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Garenoxacin mesylate
CAS:
- 223652-82-2
Garenoxacin mesylate: potent oral antibiotic for respiratory pathogens, including resistant, Gram-negative, and Gram-positive bacteria.
Fórmula:C₂₄H₂₄F₂N₂O₇S
Cor e Forma:Solid
Peso molecular:522.52
Ref: TM-T7804L