Dano de DNA/Reparo de DNA

Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.

Subcategorias de "Dano de DNA/Reparo de DNA"

Exibir 3 mais subcategorias

Foram encontrados 959 produtos de "Dano de DNA/Reparo de DNA"

Pureza (%)

100

produtos por página.

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Palifosfamide tromethamine
CAS:
- 1070409-31-2
Palifosfamide, a less toxic ifosfamide metabolite, is a DNA-alkylating anticancer agent.
Fórmula:C₈H₂₂Cl₂N₃O₅P
Cor e Forma:Solid
Peso molecular:342.16
Ref: TM-T71500
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Azemiglitazone
CAS:
- 1133819-87-0
Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.
Fórmula:C₁₉H₁₇NO₅S
Pureza:98.29% - 99.6%
Cor e Forma:Solid
Peso molecular:371.41
Ref: TM-T4639
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NMS-P118
CAS:
- 1262417-51-5
NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.
Fórmula:C₂₀H₂₄F₃N₃O₂
Pureza:98.79%
Cor e Forma:Solid
Peso molecular:395.42
Ref: TM-T4472
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Zebularine
CAS:
- 3690-10-6
Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.
Fórmula:C₉H₁₂N₂O₅
Pureza:99.04% - >99.99%
Cor e Forma:Solid
Peso molecular:228.2
Ref: TM-T2169
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Thymidine
CAS:
- 50-89-5
Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.
Fórmula:C₁₀H₁₄N₂O₅
Pureza:99.64% - 99.86%
Cor e Forma:White To Off-White Solid Crystalline
Peso molecular:242.23
Ref: TM-TWP2911
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T0070907
CAS:
- 313516-66-4
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
Fórmula:C₁₂H₈ClN₃O₃
Pureza:98.25% - 99.98%
Cor e Forma:Solid
Peso molecular:277.66
Ref: TM-T6689
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SW-100
CAS:
- 2126744-35-0
SW-100 is a potent HDAC6 inhibitor with 2.3 nM IC50, highly selective (>1000-fold), can cross blood-brain-barrier.
Fórmula:C₁₇H₁₇ClN₂O₂
Pureza:98.34% - 98.47%
Cor e Forma:Solid
Peso molecular:316.78
Ref: TM-T16962
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Pirarubicin
CAS:
- 72496-41-4
Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.
Fórmula:C₃₂H₃₇NO₁₂
Pureza:97.80% - 99.15%
Cor e Forma:Red Crystalline Powder
Peso molecular:627.64
Ref: TM-T6628
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GSK3685032
CAS:
- 2170137-61-6
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).
Fórmula:C₂₂H₂₄N₆OS
Pureza:98.56% - 99.49%
Cor e Forma:Solid
Peso molecular:420.53
Ref: TM-T9573
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Senaparib
CAS:
- 1401682-78-7
Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.
Fórmula:C₂₄H₂₀F₂N₆O₃
Pureza:99.8%
Cor e Forma:Solid
Peso molecular:478.45
Ref: TM-T9593
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L-778123 hydrochloride
CAS:
- 253863-00-2
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
Fórmula:C₂₂H₂₁Cl₂N₅O
Pureza:93.93% - 98.51%
Cor e Forma:Solid
Peso molecular:442.34
Ref: TM-T3182
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Prulifloxacin
CAS:
- 123447-62-1
Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.
Fórmula:C₂₁H₂₀FN₃O₆S
Pureza:99.47%
Cor e Forma:Yellow Or Slightly Yellow Power
Peso molecular:461.46
Ref: TM-T5394
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Ceralasertib
CAS:
- 1352226-88-0
Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib has antitumor activity. Cost effective and quality assured.
Fórmula:C₂₀H₂₄N₆O₂S
Pureza:98% - 99.99%
Cor e Forma:Solid
Peso molecular:412.51
Ref: TM-T3338
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VE-821
CAS:
- 1232410-49-9
VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).
Fórmula:C₁₈H₁₆N₄O₃S
Pureza:97.19% - 99.97%
Cor e Forma:Solid
Peso molecular:368.41
Ref: TM-T3032
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Indotecan
CAS:
- 915303-09-2
Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).
Fórmula:C₂₆H₂₆N₂O₇
Pureza:97% - 98%
Cor e Forma:Solid
Peso molecular:478.49
Ref: TM-T15578
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γ-Oryzanol
CAS:
- 11042-64-1
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the
Fórmula:C₄₀H₅₈O₄
Pureza:mixture - mixture
Cor e Forma:White Or White Crystalline Powder Odourless
Peso molecular:602.9
Ref: TM-T3606
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Thiomyristoyl
CAS:
- 1429749-41-6
Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.
Fórmula:C₃₄H₅₁N₃O₃S
Pureza:99.16%
Cor e Forma:Solid
Peso molecular:581.85
Ref: TM-T3447
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AGK7
CAS:
- 304896-21-7
AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.
Fórmula:C₂₃H₁₃Cl₂N₃O₂
Pureza:98.31%
Cor e Forma:Solid
Peso molecular:434.27
Ref: TM-T22026
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Hinokitiol
CAS:
- 499-44-5
Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.
Fórmula:C₁₀H₁₂O₂
Pureza:99.49% - 99.67%
Cor e Forma:Solid
Peso molecular:164.2
Ref: TM-T3717
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UBCS039
CAS:
- 358721-70-7
UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)
Fórmula:C₁₆H₁₃N₃
Pureza:98.31%
Cor e Forma:Solid
Peso molecular:247.29
Ref: TM-T7679