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Dano de DNA/Reparo de DNA

Dano de DNA/Reparo de DNA

Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.

Subcategorias de "Dano de DNA/Reparo de DNA"

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Foram encontrados 959 produtos de "Dano de DNA/Reparo de DNA"

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  • Rubitecan
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    Rubitecan

    CAS:
    <p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>
    Fórmula:C20H15N3O6
    Pureza:97.54%
    Cor e Forma:Yellow Amorphous Powder
    Peso molecular:393.35

    Ref: TM-T5853

  • SW-100
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    SW-100

    CAS:
    <p>SW-100 is a potent HDAC6 inhibitor with 2.3 nM IC50, highly selective (&gt;1000-fold), can cross blood-brain-barrier.</p>
    Fórmula:C17H17ClN2O2
    Pureza:98.34% - 98.47%
    Cor e Forma:Solid
    Peso molecular:316.78

    Ref: TM-T16962

  • Adenine hemisulfate
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    Adenine hemisulfate

    CAS:
    <p>Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry</p>
    Fórmula:(C5H5N5)·H2SO4
    Pureza:99.48%
    Cor e Forma:White To Light Yellow Crystal Powder
    Peso molecular:368.33

    Ref: TM-T6369

  • L-778123 hydrochloride
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    L-778123 hydrochloride

    CAS:
    <p>The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.</p>
    Fórmula:C22H21Cl2N5O
    Pureza:93.93% - 98.51%
    Cor e Forma:Solid
    Peso molecular:442.34

    Ref: TM-T3182

  • Indotecan
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    Indotecan

    CAS:
    <p>Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).</p>
    Fórmula:C26H26N2O7
    Pureza:97% - 98%
    Cor e Forma:Solid
    Peso molecular:478.49

    Ref: TM-T15578

  • AG-494
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    AG-494

    CAS:
    <p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>
    Fórmula:C16H12N2O3
    Pureza:98.69%
    Cor e Forma:Solid
    Peso molecular:280.28

    Ref: TM-T4205

  • BIBR 1532
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    BIBR 1532

    CAS:
    <p>BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).</p>
    Fórmula:C21H17NO3
    Pureza:98.49% - 98.90%
    Cor e Forma:Solid
    Peso molecular:331.36

    Ref: TM-T2380

  • Deoxycytidine triphosphate
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    Deoxycytidine triphosphate

    CAS:
    <p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>
    Fórmula:C9H16N3O13P3
    Pureza:99.68%
    Cor e Forma:Solid
    Peso molecular:467.16

    Ref: TM-T7520

  • PI3K-IN-1
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    PI3K-IN-1

    CAS:
    <p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>
    Fórmula:C31H29N5O6S
    Pureza:97.03% - 98%
    Cor e Forma:Solid
    Peso molecular:599.66

    Ref: TM-T1826

  • SRT 1720
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    SRT 1720

    CAS:
    <p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is &gt;230-fold less potent for SIRT2 and SIRT3.</p>
    Fórmula:C25H23N7OS
    Pureza:98.84%
    Cor e Forma:Solid
    Peso molecular:469.56

    Ref: TM-T5096

  • Prexasertib
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    Prexasertib

    CAS:
    <p>Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50&lt;1 nM). antitumor activity. High-Quality, Low-Cost!</p>
    Fórmula:C18H19N7O2
    Pureza:97.3% - 98.23%
    Cor e Forma:Solid
    Peso molecular:365.39

    Ref: TM-T4310

  • RK-287107
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    RK-287107

    CAS:
    <p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>
    Fórmula:C22H26F2N4O2
    Pureza:99.64%
    Cor e Forma:Solid
    Peso molecular:416.46

    Ref: TM-T16761

  • GW9662
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    GW9662

    CAS:
    <p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>
    Fórmula:C13H9ClN2O3
    Pureza:98% - 99.95%
    Cor e Forma:Off-White Solid
    Peso molecular:276.68

    Ref: TM-T2260

  • Garenoxacin mesylate
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    Garenoxacin mesylate

    CAS:
    <p>Garenoxacin mesylate: potent oral antibiotic for respiratory pathogens, including resistant, Gram-negative, and Gram-positive bacteria.</p>
    Fórmula:C24H24F2N2O7S
    Cor e Forma:Solid
    Peso molecular:522.52

    Ref: TM-T7804L

  • Seladelpar sodium salt
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    Seladelpar sodium salt

    CAS:
    <p>Seladelpar sodium (MBX-8025) is a potent oral PPARδ agonist, EC50 of 2 nM, &gt;750x selective over PPARα, &gt;2500x over PPARγ.</p>
    Fórmula:C21H22F3NaO5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:466.45

    Ref: TM-T12876

  • PI-3065
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    PI-3065

    CAS:
    <p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>
    Fórmula:C27H31FN6OS
    Pureza:99.84% - ≥95%
    Cor e Forma:Solid
    Peso molecular:506.64

    Ref: TM-T2083

  • KU-57788
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    KU-57788

    CAS:
    <p>NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).</p>
    Fórmula:C25H19NO3S
    Pureza:98% - >99.99%
    Cor e Forma:Solid
    Peso molecular:413.49

    Ref: TM-T6276

  • Deoxythymidine-5'-triphosphate trisodium
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    Deoxythymidine-5'-triphosphate trisodium

    CAS:
    <p>dTTP trisodium salt, a natural deoxynucleotide for DNA synthesis by DNA polymerase and reverse transcriptase.</p>
    Fórmula:C10H14N2Na3O14P3
    Pureza:97.47%
    Cor e Forma:Solid
    Peso molecular:548.11

    Ref: TM-T9086

  • 1,4-Naphthoquinone
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    1,4-Naphthoquinone

    CAS:
    <p>1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.</p>
    Fórmula:C10H6O2
    Pureza:99.24% - 99.56%
    Cor e Forma:Solid
    Peso molecular:158.15

    Ref: TM-T7048

  • Tasquinimod
    Targetmol
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    Tasquinimod

    CAS:
    <p>Tasquinimod (ABR-215050) is an oral antiangiogenic agent and S100A9 inhibitor that binds to the HDAC4Zn2+ binding structural domain with Kd values ranging from 10 to 30 nM.Cost-effective and quality-assured.</p>
    Fórmula:C20H17F3N2O4
    Pureza:99.22% - >99.99%
    Cor e Forma:Solid
    Peso molecular:406.36

    Ref: TM-T6695