Topoisomerase
As topoisomerases são enzimas que regulam a topologia do DNA durante processos como replicação, transcrição e segregação cromossômica, introduzindo quebras temporárias nas fitas de DNA para aliviar o estresse torsional. Os inibidores de topoisomerase interferem nesse processo, levando ao acúmulo de quebras de DNA e à indução da morte celular, particularmente em células de rápida divisão. Esses inibidores são amplamente utilizados como agentes quimioterápicos no tratamento do câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de topoisomerase de alta qualidade para apoiar sua pesquisa em replicação de DNA, terapia do câncer e regulação do ciclo celular.
Foram encontrados 132 produtos de "Topoisomerase"
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Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Fórmula:C27H29NO11·HClPureza:98% - 99.52%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99Teniposide
CAS:Teniposide (VM26), a semisynthetic derivative of podophyllotoxin with antitumor activity, inhibits DNA synthesis by forming a complex with topoisomerase II andFórmula:C32H32O13SPureza:97.7% - 99.45%Cor e Forma:White Or Off-White Crystalline PowderPeso molecular:656.65Moxifloxacin hydrochloride
CAS:Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria and atypical pathogens.Fórmula:C21H25ClFN3O4Pureza:99.91% - >99.99%Cor e Forma:SolidPeso molecular:437.89Enoxacin hydrate
CAS:Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.Fórmula:C15H17FN4O3H2OPureza:99.50%Cor e Forma:SolidPeso molecular:347.34Nalidixic acid
CAS:Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal range.Fórmula:C12H12N2O3Pureza:99.9% - 99.95%Cor e Forma:Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)Peso molecular:232.24Lurtotecan
CAS:Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.
Fórmula:C28H30N4O6Pureza:99.18%Cor e Forma:SoildPeso molecular:518.56Epirubicin hydrochloride
CAS:Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.Fórmula:C27H30ClNO11Pureza:98.13% - 99.79%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.98Ref: TM-T0125
2mg37,00€5mg52,00€10mg84,00€25mg142,00€50mg226,00€100mg308,00€500mg745,00€1mL*10mM (DMSO)70,00€Nalidixic acid sodium salt
CAS:Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.Fórmula:C12H11N2NaO3Pureza:99.72% - 99.95%Cor e Forma:White To Off-White PowderPeso molecular:254.22Daunorubicin hydrochloride
CAS:Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFórmula:C27H29NO10·HClPureza:96.21% - 99.53%Cor e Forma:Cancer DrugPeso molecular:563.99Ref: TM-T1511
5mg34,00€10mg52,00€25mg87,00€50mg113,00€100mg177,00€200mg281,00€500mg442,00€1mL*10mM (DMSO)59,00€Berberine chloride
CAS:Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.Fórmula:C20H18ClNO4Pureza:99.47% - 99.93%Cor e Forma:Yellow Crystalline PowderPeso molecular:371.80Mitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Fórmula:C22H30Cl2N4O6Pureza:97.05% - >99.99%Cor e Forma:Blue-Black Solid From Water Ethanol SolidPeso molecular:517.4Ciprofloxacin monohydrochloride
CAS:Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.Fórmula:C17H18FN3O3·HClPureza:99.5% - 99.73%Cor e Forma:White Or Light Yellow Crystalline PowderPeso molecular:367.80Ciprofloxacin
CAS:Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!Fórmula:C17H18FN3O3Pureza:98.77% - 99.91%Cor e Forma:White PowderPeso molecular:331.34Topotecan hydrochloride
CAS:Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.Fórmula:C23H24ClN3O5Pureza:97.88% - 99.41%Cor e Forma:White Crystalline SolidPeso molecular:457.92Irinotecan hydrochloride trihydrate
CAS:Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Fórmula:C33H45ClN4O9Pureza:98.22% - >99.99%Cor e Forma:Pale Yellow To Yellow Crystalline PowderPeso molecular:677.18Oxaquin TEA
Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that can be used to study Clostridium difficile infections and
Fórmula:C37H48F2N5O11PPureza:99.79%Cor e Forma:SolidPeso molecular:807.77Irinotecan Hydrochloride
CAS:Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Fórmula:C33H39ClN4O6Pureza:98% - 99.94%Cor e Forma:Yellow Crystalline PowderPeso molecular:623.14Ref: TM-T0486L
10mg34,00€25mg49,00€50mg65,00€100mg89,00€200mg129,00€500mg254,00€1mL*10mM (DMSO)71,00€Gatifloxacin
CAS:Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.Fórmula:C19H22FN3O4Pureza:99.50% - 99.85%Cor e Forma:White PowderPeso molecular:375.39Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.
Fórmula:C20H24N2O2SPureza:98.78%Cor e Forma:Yellow-Orange Powder (Ntp 1992)Peso molecular:356.48Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Fórmula:C18H20FN3O4H2OPureza:98.26%Cor e Forma:Pale Yellow SolidPeso molecular:370.38
