RAAS
Os inibidores do sistema renina-angiotensina-aldosterona (RAAS) são compostos que têm como alvo a via RAAS, conhecida principalmente por seu papel na regulação da pressão arterial e do equilíbrio de fluidos, mas que também influencia a angiogênese. A via RAAS pode contribuir para o desenvolvimento de novos vasos sanguíneos em tumores, apoiando assim seu crescimento. Inibir componentes do RAAS pode, portanto, ter efeitos antiangiogênicos, tornando esses inibidores valiosos no tratamento de certos tipos de câncer e distúrbios vasculares. Na CymitQuimica, oferecemos uma gama de inibidores de alta qualidade do RAAS para apoiar sua pesquisa em biologia cardiovascular, oncologia e angiogênese.
Foram encontrados 90 produtos de "RAAS"
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Angiotensin I/II (1-5)
CAS:Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.Fórmula:C30H48N8O9Pureza:>99.99%Cor e Forma:SolidPeso molecular:664.75Saralasin acetate(34273-10-4 free base)
CAS:Saralasin acetate is a Non-selective angiotensin II antagonist.Fórmula:C44H71N13O13Pureza:99.74%Cor e Forma:SolidPeso molecular:990.11PD 123319
CAS:PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.Fórmula:C31H32N4O3Pureza:98.61% - 99.65%Cor e Forma:SolidPeso molecular:508.61Olodanrigan sodium
CAS:Olodanrigan sodium (EMA-401 sodium) is an AT2R antagonist, used for neurological disease research.Fórmula:C32H28NNaO5Pureza:98.14%Cor e Forma:SolidPeso molecular:529.56Olodanrigan
CAS:Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation.Fórmula:C32H29NO5Pureza:98.33%Cor e Forma:SolidPeso molecular:507.58Azilsartan Medoxomil
CAS:Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adultsFórmula:C30H24N4O8Pureza:99.83%Cor e Forma:SolidPeso molecular:568.53VTP-27999 TFA
CAS:VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).Fórmula:C28H42ClF3N4O7Pureza:98.84%Cor e Forma:SolidPeso molecular:639.1SSAA09E2
CAS:<p>SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-</p>Fórmula:C16H20N4O2Pureza:99.41%Cor e Forma:SolidPeso molecular:300.36Acein acetate
<p>ACE ligand with Kd 2.79 nM, inactive on ACE up to 500 nM. Boosts NMDA/D-serine-induced dopamine release in striatum.</p>Fórmula:C45H72N10O15Pureza:99.43%Cor e Forma:SolidPeso molecular:993.11Azilsartan Methyl Ester
CAS:<p>Azilsartan Methyl Ester, an angiotensin II blocker, inhibits [125I]AII binding to adrenal cortex; IC50: 0.44uM.</p>Fórmula:C26H22N4O5Pureza:99.87%Cor e Forma:SolidPeso molecular:470.48Methyl candesartan
CAS:Methyl candesartan (Candesartan Methyl Ester) 是一种有效的血管紧张素2受体拮抗剂，可用于研究高血压。Fórmula:C25H22N6O3Pureza:98.82%Cor e Forma:SolidPeso molecular:454.48Faricimab
CAS:Faricimab,Bispecific antibody targeting Ang-2/VEGF-A. Prevents retinal I/R injury. Improves vision in w-AMD, DME, RVO.Pureza:>95% (SDS-PAGE); >95% (SEC-HPLC) - >95% (SDS-PAGE); >95% (SEC-HPLC)Cor e Forma:LiquidLosartan D4
CAS:Losartan D4 (DuP-753 D4) is a deuterated isotope of Losartan for isotopic tracing. Losartan is an angiotensin II receptor antagonist (IC50=20 nM).Fórmula:C22H23ClN6OPureza:98%Cor e Forma:SolidPeso molecular:426.94VTP-27999
CAS:VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.Fórmula:C26H41ClN4O5Pureza:98%Cor e Forma:SolidPeso molecular:525.08UR-7247
CAS:UR-7247 is an orally active AT1 receptor antagonist with long-lasting effects, high protein binding, and potential application in cardiovascular pharmacology studies.Fórmula:C24H26N6O2Pureza:100% - 98.88%Cor e Forma:SolidPeso molecular:430.5CGP48369
CAS:<p>CGP48369 is a potent angiotensin II receptor antagonist with antihypertensive effects that enhances endothelium-dependent relaxation of coronary arteries in</p>Fórmula:C26H30N6OPureza:99.27%Cor e Forma:SolidPeso molecular:442.56Pomisartan
CAS:Pomisartan (BIBR-363) is a small molecule angiotensin type 1 receptor (AT1R) antagonist that is used in the treatment of cardiovascular disease, studying heartFórmula:C31H30N4O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:490.6L162441
CAS:L162441 is an antagonist of Angiotensin type 1 receptor.Fórmula:C34H43N5O5SPureza:98%Cor e Forma:SolidPeso molecular:633.8Pratosartan
CAS:Pratosartan is a selective antagonist of angiotensin II receptor.Fórmula:C25H26N6OPureza:98%Cor e Forma:SolidPeso molecular:426.51BMS 183920
CAS:BMS 183920 is a potent Angiotensin II Receptor antagonist that improves improves Caco-2 cell permeability in vivo.Fórmula:C26H19N5O3Pureza:98.92%Cor e Forma:SolidPeso molecular:449.46
