RAAS
Os inibidores do sistema renina-angiotensina-aldosterona (RAAS) são compostos que têm como alvo a via RAAS, conhecida principalmente por seu papel na regulação da pressão arterial e do equilíbrio de fluidos, mas que também influencia a angiogênese. A via RAAS pode contribuir para o desenvolvimento de novos vasos sanguíneos em tumores, apoiando assim seu crescimento. Inibir componentes do RAAS pode, portanto, ter efeitos antiangiogênicos, tornando esses inibidores valiosos no tratamento de certos tipos de câncer e distúrbios vasculares. Na CymitQuimica, oferecemos uma gama de inibidores de alta qualidade do RAAS para apoiar sua pesquisa em biologia cardiovascular, oncologia e angiogênese.
Foram encontrados 91 produtos para "RAAS".
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[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Fórmula:C48H77N13O12Pureza:99.36%Cor e Forma:SolidPeso molecular:1028.2Ref: TM-T7575L1
2mg34,00€5mg46,00€10mg60,00€1mL*10mM (DMSO)90,00€25mg119,00€50mg192,00€100mg289,00€200mg415,00€Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Fórmula:C54H101N15O12SPureza:98%Cor e Forma:SolidPeso molecular:1184.54Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Fórmula:C30H23N4O8·KPureza:99.99%Cor e Forma:SolidPeso molecular:606.62TRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Fórmula:C52H74N14O13Cor e Forma:SolidPeso molecular:1103.249[Sar1, Ile8]-Angiotensin II TFA
[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.Fórmula:C48H74F3N13O12Pureza:98%Cor e Forma:SolidPeso molecular:1082.18Evazarsen sodium
CAS:Evazarsen sodium, an angiotensinogen synthesis inhibitor, possesses antihypertensive properties [1].Fórmula:C296H414N86O146P20S19Na20Cor e Forma:SolidPeso molecular:9201.6TRV120055
CAS:TRV120055 is a Gq-biased agonist with 10x more efficacy on AT1R-Gq than AT1R-βarr2.Fórmula:C34H54N12O7Peso molecular:742.883Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Fórmula:C42H55F3N8O10Pureza:98%Cor e Forma:SolidPeso molecular:888.93Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Fórmula:C26H38F3N7O10Pureza:98%Cor e Forma:SolidPeso molecular:665.62A 779
CAS:A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Fórmula:C39H60N12O11Pureza:98%Cor e Forma:SolidPeso molecular:872.97Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Fórmula:C24H37N7O8Pureza:98%Cor e Forma:SolidPeso molecular:551.59PRO20
PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.Cor e Forma:Odour SolidCGP-42112 acetate
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.Fórmula:C54H73N13O13Pureza:99.06% - 99.92%Cor e Forma:SolidPeso molecular:1112.24Ref: TM-T14939L
1mg93,00€5mg279,00€10mg403,00€1mL*10mM (DMSO)622,00€25mg623,00€50mg837,00€100mg1.108,00€200mg1.504,00€Aliskiren-D6 hydrochloride
CAS:Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).Fórmula:C30H54ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:594.26[Sar1, Ile8]-Angiotensin II
CAS:[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Fórmula:C46H73N13O10Pureza:98%Cor e Forma:SolidPeso molecular:968.15Angiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Fórmula:C78H125N25O23Cor e Forma:SolidPeso molecular:1780.98Losartan (D4 Carboxylic Acid)
CAS:Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.Fórmula:C22H21ClN6O2Pureza:98%Cor e Forma:SolidPeso molecular:440.919PD 123319 ditrifluoroacetate
CAS:PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.Fórmula:C35H34F6N4O7Pureza:98%Cor e Forma:White SolidPeso molecular:736.66Valsartan-D9
CAS:Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.Fórmula:C24H29N5O3Pureza:98%Cor e Forma:SolidPeso molecular:444.574Spirapril hydrochloride
CAS:Spirapril hydrochloride (SCH 33844 hydrochloride) is a potent angiotensin converting enzyme inhibitor with antihypertensive activity that competitively blocks the conversion of angiotensin I to angiotensin II, functions as an orally active proagent of spiraprilat, and is extensively utilized in cardiovascular research focused on hypertension and congestive heart failure pathophysiology and therapeutic intervention.Fórmula:C22H31ClN2O5S2Pureza:99.78%Peso molecular:503.07
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