RAAS

Os inibidores do sistema renina-angiotensina-aldosterona (RAAS) são compostos que têm como alvo a via RAAS, conhecida principalmente por seu papel na regulação da pressão arterial e do equilíbrio de fluidos, mas que também influencia a angiogênese. A via RAAS pode contribuir para o desenvolvimento de novos vasos sanguíneos em tumores, apoiando assim seu crescimento. Inibir componentes do RAAS pode, portanto, ter efeitos antiangiogênicos, tornando esses inibidores valiosos no tratamento de certos tipos de câncer e distúrbios vasculares. Na CymitQuimica, oferecemos uma gama de inibidores de alta qualidade do RAAS para apoiar sua pesquisa em biologia cardiovascular, oncologia e angiogênese.

Foram encontrados 97 produtos para "RAAS".

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produtos por página.

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BMS 183920
CAS:
- 153072-33-4
BMS 183920 is a potent Angiotensin II Receptor antagonist that improves improves Caco-2 cell permeability in vivo.
Fórmula:C₂₆H₁₉N₅O₃
Pureza:98.92%
Cor e Forma:Yellow Solid
Peso molecular:449.46
Ref: TM-T30491
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Pratosartan
CAS:
- 153804-05-8
Pratosartan is a selective antagonist of angiotensin II receptor.
Fórmula:C₂₅H₂₆N₆O
Pureza:98%
Cor e Forma:Solid
Peso molecular:426.51
Ref: TM-T16573
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L162441
CAS:
- 154512-46-6
L162441 is an antagonist of Angiotensin type 1 receptor.
Fórmula:C₃₄H₄₃N₅O₅S
Pureza:98%
Cor e Forma:Solid
Peso molecular:633.8
Ref: TM-T11809
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Pomisartan
CAS:
- 144702-17-0
Pomisartan (BIBR-363) is a small molecule angiotensin type 1 receptor (AT1R) antagonist that is used in the treatment of cardiovascular disease, studying heart
Fórmula:C₃₁H₃₀N₄O₂
Pureza:>99.99%
Cor e Forma:Solid
Peso molecular:490.5955
Ref: TM-T28437
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Tolonidine
CAS:
- 4201-22-3
Tolonidine is an alpha-adrenergic receptor agonist that exerts antihypertensive effects by reducing vascular resistance and modulating cardiac function.
Fórmula:C₁₀H₁₂ClN₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:209.675
Ref: TM-T17113
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CGP48369
CAS:
- 135689-23-5
CGP48369 is a potent angiotensin II receptor antagonist with antihypertensive effects that enhances endothelium-dependent relaxation of coronary arteries in
Fórmula:C₂₆H₃₀N₆O
Pureza:99.27%
Cor e Forma:White Solid
Peso molecular:442.56
Ref: TM-T14942
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Buloxibutid
CAS:
- 477775-14-7
Buloxibutid: a novel AT2 receptor agonist, Ki=0.4 nM (AT2), 10 μM (AT1).
Fórmula:C₂₃H₂₉N₃O₄S₂
Pureza:98.10% - 98.24%
Cor e Forma:Yellow Solid
Peso molecular:475.624
Ref: TM-T14337
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Terlakiren
CAS:
- 119625-78-4
Terlakiren (CP-80,794) is a renin inhibitor that inhibits the potency of human renin and can be used to study neurological disorders of the hypertensive type.
Fórmula:C₃₁H₄₈N₄O₇S
Pureza:99.38%
Cor e Forma:Solid
Peso molecular:620.8
Ref: TM-T28950
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Ripisartan
CAS:
- 148504-51-2
Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.
Fórmula:C₂₃H₂₂N₈O
Pureza:98.52%
Cor e Forma:Solid
Peso molecular:426.4738
Ref: TM-T28540
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ZD-6888 Hydrochloride
CAS:
- 138620-17-4
ZD-6888 Hydrochloride, an angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension.
Fórmula:C₂₅H₂₆ClN₅O
Pureza:99.43% - 99.60%
Cor e Forma:White Solid
Peso molecular:447.96
Ref: TM-T29211
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L-162,313
CAS:
- 151488-11-8
L-162,313 is an ANG II receptor agonist, a nonpeptide that mimics the biological actions of angiotensin II and induces an increase in MAP.
Fórmula:C₃₀H₃₈N₄O₄S₂
Pureza:98.21%
Cor e Forma:White Solid
Peso molecular:582.777
Ref: TM-T27762
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CL-329167
CAS:
- 143945-39-5
CL-329167 (compound 12) is an orally active, competitive angiotensin II receptor antagonist (IC50=6 nM) suitable for hypertension research.
Fórmula:C₃₀H₃₂N₆O₂
Pureza:99.08% - 99.42%
Cor e Forma:Solid
Peso molecular:508.61
Ref: TM-T27037
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SPH3127
CAS:
- 1399849-02-5
SPH3127 (DRI 18) is a direct renin inhibitor used in blood pressure and renin–angiotensin system research.
Fórmula:C₂₂H₃₂N₆O₄
Pureza:99.88%
Cor e Forma:Solid
Peso molecular:444.53
Ref: TM-T62618
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L162389
CAS:
- 169281-53-2
L162389 is an angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor and stimulates the conversion of phosphatidylinositol.
Fórmula:C₃₁H₃₈N₄O₄S
Pureza:98.11% - 99.11%
Cor e Forma:White Solid
Peso molecular:562.72
Ref: TM-T11808
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KR31173
CAS:
- 260554-07-2
KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. When labeled with the 11C isotope, KR31173 can be used as a tracer for positron emission tomography (PET). In mice, KR31173 exhibits favorable biodistribution and pharmacological characteristics. It selectively binds to organs in CD-1 mice known to have a high density of AT1 angiotensin receptors.
Fórmula:C₃₁H₃₀N₈O₂
Cor e Forma:Solid
Peso molecular:546.62
Ref: TM-T207150
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ACT 178882
CAS:
- 1007392-69-9
ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).
Fórmula:C₃₃H₃₈Cl₃N₃O₄
Pureza:98%
Cor e Forma:Solid
Peso molecular:647.03
Ref: TM-T14123
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ZD 7155 hydrochloride
CAS:
- 146709-78-6
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
Fórmula:C₂₆H₂₇ClN₆O
Pureza:99.8%
Cor e Forma:White Solid
Peso molecular:474.985
Ref: TM-T13390

RAAS

Foram encontrados 97 produtos para "RAAS".

BMS 183920

Ref: TM-T30491

Pratosartan

Ref: TM-T16573

L162441

Ref: TM-T11809

Pomisartan

Ref: TM-T28437

Tolonidine

Ref: TM-T17113

CGP48369

Ref: TM-T14942

Buloxibutid

Ref: TM-T14337

Terlakiren

Ref: TM-T28950

Ripisartan

Ref: TM-T28540

ZD-6888 Hydrochloride

Ref: TM-T29211

L-162,313

Ref: TM-T27762

CL-329167

Ref: TM-T27037

SPH3127

Ref: TM-T62618

L162389

Ref: TM-T11808

KR31173

Ref: TM-T207150

ACT 178882

Ref: TM-T14123

ZD 7155 hydrochloride

Ref: TM-T13390