RAAS
Os inibidores do sistema renina-angiotensina-aldosterona (RAAS) são compostos que têm como alvo a via RAAS, conhecida principalmente por seu papel na regulação da pressão arterial e do equilíbrio de fluidos, mas que também influencia a angiogênese. A via RAAS pode contribuir para o desenvolvimento de novos vasos sanguíneos em tumores, apoiando assim seu crescimento. Inibir componentes do RAAS pode, portanto, ter efeitos antiangiogênicos, tornando esses inibidores valiosos no tratamento de certos tipos de câncer e distúrbios vasculares. Na CymitQuimica, oferecemos uma gama de inibidores de alta qualidade do RAAS para apoiar sua pesquisa em biologia cardiovascular, oncologia e angiogênese.
Foram encontrados 93 produtos para "RAAS".
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BIBS 39
CAS:BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.Fórmula:C32H36N4O3Pureza:99.28%Cor e Forma:White SolidPeso molecular:524.65UR-7247
CAS:UR-7247 is an orally active AT1 receptor antagonist with long-lasting effects, high protein binding, and potential application in cardiovascular pharmacology studies.Fórmula:C24H26N6O2Pureza:100% - 98.88%Cor e Forma:SolidPeso molecular:430.5Terlakiren
CAS:Terlakiren (CP-80,794) is a renin inhibitor that inhibits the potency of human renin and can be used to study neurological disorders of the hypertensive type.Fórmula:C31H48N4O7SPureza:99.38%Cor e Forma:SolidPeso molecular:620.8Buloxibutid
CAS:Buloxibutid: a novel AT2 receptor agonist, Ki=0.4 nM (AT2), 10 μM (AT1).Fórmula:C23H29N3O4S2Pureza:98.10% - 98.24%Cor e Forma:Yellow SolidPeso molecular:475.62Ref: TM-T14337
1mg47,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg145,00€25mg260,00€50mg409,00€100mg708,00€500mg1.423,00€Ripisartan
CAS:Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.Fórmula:C23H22N8OPureza:98.52%Cor e Forma:SolidPeso molecular:426.47L-162,313
CAS:L-162,313 is an ANG II receptor agonist, a nonpeptide that mimics the biological actions of angiotensin II and induces an increase in MAP.Fórmula:C30H38N4O4S2Pureza:98.21%Cor e Forma:White SolidPeso molecular:582.78ZD-6888 Hydrochloride
CAS:ZD-6888 Hydrochloride, an angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension.Fórmula:C25H26ClN5OPureza:99.43% - 99.60%Cor e Forma:White SolidPeso molecular:447.96CL-329167
CAS:CL-329167 (compound 12) is an orally active, competitive angiotensin II receptor antagonist (IC50=6 nM) suitable for hypertension research.Fórmula:C30H32N6O2Pureza:99.08% - 99.42%Cor e Forma:SolidPeso molecular:508.61SPH3127
CAS:SPH3127 (DRI 18) is a direct renin inhibitor used in blood pressure and renin–angiotensin system research.Fórmula:C22H32N6O4Pureza:99.88%Cor e Forma:SolidPeso molecular:444.53KR31173
CAS:KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. When labeled with the 11C isotope, KR31173 can be used as a tracer for positron emission tomography (PET). In mice, KR31173 exhibits favorable biodistribution and pharmacological characteristics. It selectively binds to organs in CD-1 mice known to have a high density of AT1 angiotensin receptors.Fórmula:C31H30N8O2Cor e Forma:SolidPeso molecular:546.62ACT 178882
CAS:ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).Fórmula:C33H38Cl3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:647.03L162389
CAS:L162389 is an angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor and stimulates the conversion of phosphatidylinositol.Fórmula:C31H38N4O4SPureza:98.11% - 99.11%Cor e Forma:White SolidPeso molecular:562.72ZD 7155 hydrochloride
CAS:ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.Fórmula:C26H27ClN6OPureza:99.8%Cor e Forma:White SolidPeso molecular:474.98Ref: TM-T13390
1mg39,00€5mg84,00€1mL*10mM (DMSO)86,00€10mg128,00€25mg222,00€50mg375,00€100mg602,00€200mg840,00€
